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Metabolic Diseases (17)
- Acid-Base Imbalance
- Brain Diseases, Metabolic
- Calcium Metabolism Disorders
- DNA Repair-Deficiency Disorders
- Glucose Metabolism Disorders
- Iron Metabolism Disorders
- Lipid Metabolism Disorders
- Malabsorption Syndromes
Articles on Metabolic Diseases
Weight loss and metabolic improvement in morbidly obese subjects implanted for 1 year with an endoscopic duodenal-jejunal bypass liner.
These results suggest that this device may be suitable for the treatment of morbid obesity and its related comorbidities. This study was registered at www.clinicaltrials.gov (NCT00985491)....
Roles of vitamin A status and retinoids in glucose and fatty acid metabolism.
The rising prevalence of metabolic diseases, such as obesity and diabetes, has become a public health concern. Vitamin A (VA, retinol) is an essential micronutrient for a variety of physiological processes, such as tissue differentiation, immunity, and vision. However, its role in gl...
Relationship between the Bertin index to estimate visceral adipose tissue from dual-energy X-ray absorptiometry and cardiometabolic risk fac...
We measured (i) VAT using CT scan, (ii) body composition (using DXA) from which the Bertin index was calculated, (iii) cardiometabolic risk factors such as insulin sensitivity (using the hyperinsulinenic-euglycemic clamp technique), peak oxygen consumption, blood pressure, plasma lipids, C-reactive...
Angiopoietin-like protein 4: health effects, modulating agents and structure-function relationships.
We will focus on: health issues associated with ANGPTL4 expression, including obesity, Type 2 diabetes, cardiovascular diseases and cancer; several modulators of ANGPTL4 of chemical, microbiological, food and host origin; and the correlation of the specific ANGPTL4 isoforms with these modulators and...
Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents.
Sparse data exist on the combined associations between physical activity and sedentary time with cardiometabolic risk factors in healthy children. To examine the independent and combined associations between objectively measured time in moderate- to vigorous-intensity...
Fatness, fitness, and cardiometabolic risk factors in middle-aged white men.
The objective was to test the hypothesis that traditional and novel cardiometabolic risk factors would be significantly different in groups of men of different fatness and fitness. Total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycer...
Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus.
We determined expression and regulation of mitochondrial enzymes including pyruvate dehydrogenase kinase (PDK) 4, PDK2, carnitine palmitoyltransferase 1b, and malonyl-coenzyme A decarboxylase in skeletal muscle from people with normal glucose tolerance (NGT) or type 2 diabetes mellitus (T2DM). Vastu...
Mitochondrial DNA and inflammatory diseases.
Increasing experimental evidence supports a connection between inflammation and mitochondrial dysfunction. Both acute and chronic inflammatory diseases course with elevated free radicals production that may affect mitochondrial proteins, lipids, and mtDNA. The subsequent mitochondria...
Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
To compare the characteristics of female versus male gout patients and assess urate-lowering efficacy and safety of febuxostat or allopurinol treatment in women with gout. This was a retrospective analysis of 4,101 hyperuricemic (serum urate [sUA] level ≥8.0 mg/dl)...