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Methacycline (0):
Recent article
Methacycline
Abstract
The fluorescence of metacycline enhanced by the synergetic effect of beta-cyclodextrin with anion surfactant sodium dodecylbenzene sulfonate (DBS) was studied. It was found that the fluorescence intensity of metacycline was greatly enhanced in the system of beta-CD-DBS. Based on this a new sensitive...
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PMID: 19271508
PDF is available here.
PDF is available here.
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Journal of Chromatography A (1195)1-2 2008
Abstract
Eight antibiotics, chlortetracycline, demeclocycline, doxycycline, methacycline, minocycline, oxytetracycline, tetracycline and rolitetracycline, were separated and quantified in Spanish honey extracts of different floral origin using a commercial RP-C18 HPLC column and two different on-line detecto...
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PMID: 18501371
PDF is available here.
PDF is available here.
Abstract
An automated system using on-line solid-phase extraction (SPE) high-performance liquid chromatography (HPLC) with ultraviolet (UV) detection was developed for the determination of tetracyclines (TCs), such as tetracycline (TC), oxytetracycline (OTC), chlortetracycline (CTC), metacycline (MC), and do...
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PMID: 18585209
PDF is available here.
PDF is available here.
Analytical Sciences (23)2 2007
Abstract
An internal solid contact sensor (ISCS) for the determination of methacycline hydrochloride (MC.Cl), Pt/PPy/PVC(MC-PT), is described, based on the use of conducting poly(pyrrole) (PPy) as solid contact material and MC-phosphotungstate (PT) as the ion exchanger and dibutyl phthalate (DBP) as the plas...
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PMID: 17297239
PDF is available here.
PDF is available here.
Abstract
A new synchronous-derivative fluorimetric method for the determination of metacycline (MTC) in the presence of oxytetracycline (OTC) is proposed. The degradation products of MTC in 0.1 mol x L(-1) NaOH are strongly fluorescent. The addition of cetyltrimethylammonium bromide (CTMAB) enhances the fluo...
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PMID: 17058964
PDF is available here.
PDF is available here.
Electrophoresis (27)12 2006
Abstract
A CE method for metacycline (MTC) determination was investigated in an inter-laboratory experiment. Many problems were encountered in this study, most of which were related to the transfer of the method to different CE equipment. The reported problems could be classified into differe...
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PMID: 16718715
PDF is available here.
PDF is available here.
Analytical Sciences (21)5 2005
Abstract
A new spectrofluorometric method is described for the determination of metacycline (MC), based on modified enzyme-amplified lanthanide luminescence. Under the optimum conditions, Eu3+-MC forms a ternary complex with lysozyme in close proximity. Then lysozyme can remarkably enhance the characteristic...
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PMID: 15913144
PDF is available here.
PDF is available here.
Abstract
Demeclocycline (DM) and methacycline (MT) have been determined by europium-sensitized fluorescence, using EDTA as co-ligand and cetyltrimethylammonium chloride as surfactant. The methods have been developed in slightly alkaline solutions, with the formation of a new chelate where the lanthanide ion...
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PMID: 15862691
PDF is available here.
PDF is available here.
Abstract
There are a number of drug interactions reported for tetracyclines with many other drugs. In present study in vitro release of five different tetracyclines i.e., tetracycline, demeclocycline, oxytetracycline, methacycline and doxycycline in presence of cimetidine and ranitidine has been studied by U...
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PMID: 16431401
PDF is available here.
PDF is available here.
Stomatologiia (82)5 2003
Abstract
The efficiency of preventive oral antibiotic therapy before the root channel filling was evaluated in 78 patients with granulating and granulomatous chronic periodontitis. Positive clinical changes were observed after lincomycin or rondomycin therapy (p = 0.017). The number of complaints was also le...
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PMID: 14608343
PDF is available here.
PDF is available here.
Electrophoresis (22)3 2001
Abstract
The development and validation of an optimized capillary electrophoresis method for the determination of metacycline in the presence of its related substances by capillary electrophoresis is shown. The influence of methanol as organic modifier, buffer pH, buffer concentration, capillary length, colu...
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PMID: 11258761
PDF is available here.
PDF is available here.
Abstract
The serine proteinase tissue-type plasminogen activator (t-PA) and the metalloproteinase gelatinase B (MMP-9) have recently been demonstrated in MS lesions. Both enzymes are interconnected in an enzyme cascade which contributes to destruction of the blood brain barrier and demyelination and both enz...
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PMID: 9599337
PDF is available here.
PDF is available here.
Abstract
A sensitive high-performance liquid chromatographic technique with amperometric detection has been developed for the determination of seven commercially used tetracyclines in bulk powders and pharmaceutical preparations. The technique is based on the oxidation of these compounds and their contaminan...
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PMID: 9502164
PDF is available here.
PDF is available here.
Abstract
We implemented an algorithm named OSPOP 1.0, based on non-adaptive random search (RS) followed by stochastic gradient to determine optimal sampling times for parameter estimation in various pharmacokinetic models according to ED, EID and API criteria. Prior distributions are allowed to be uniform, n...
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PMID: 8835836
PDF is available here.
PDF is available here.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoi i mikrobiologicheskoi promyshlennosti SSSR (39)5 1994
Abstract
MICs and MBcCs of minocycline, doxycycline, methacycline and chlortetracycline for 8 strains of Pseudomonas mallei were determined. The chemotherapeutic efficacy of minocycline and doxycycline was studied on golden hamsters and their efficacy indices were estimated in comparison with those of chlort...
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PMID: 7857158
PDF is available here.
PDF is available here.
Abstract
A new continuous separation method was developed for the determination of five different tetracyclines (oxytetracycline, tetracycline, chlortetracycline, methacycline and doxycycline). A bioassay using minimum medium (MM) seeded with Bacillus subtilis ATCC 6633 was carried out for the detection, wit...
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PMID: 8073177
PDF is available here.
PDF is available here.
Abstract
Use of optimal sampling theory (OST) in pharmacokinetic studies allows the number of sampling times to be greatly reduced without loss in parameter estimation precision. OST has been applied to the determination of the bioavailability parameters (area under the curve (AUC), maximal concentration (Cm...
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PMID: 7815309
PDF is available here.
PDF is available here.
Abstract
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoi i mikrobiologicheskoi promyshlennosti SSSR (38)1 1993
Abstract
Abstract
Chemiluminescence (CL) appearing during autoxidation of tetracycline (TC) antibiotics has been studied. The CL spectrum consists of four emission bands with maxima at 520, 585, 640 and 700 nm. The bands at 585, 640 and 700 nm are similar to those observed for singlet molecular oxygen (1O2). The effe...
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PMID: 1328577
PDF is available here.
PDF is available here.
Abstract
Endometrial, endocervical, and urethral specimens were obtained from 16 nonpregnant women with a history of habitual abortions. Chlamydia were isolated from the endometria of 4 women, but only in one case chlamydial intracytoplasmic incorporations in endometrial cells were detectable by the Romanovs...
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PMID: 1476220
PDF is available here.
PDF is available here.
Journal of Chromatography A (586)1 1991
Abstract
Isocratic column liquid chromatography on poly(styrene-divinylbenzene) copolymer allowed complete separation of metacycline, 4-epimetacycline, oxytetracycline, doxycycline and 6-epidoxycycline. 2-Acetyl-2-decarboxamidometacycline was eluted on the tail of metacycline. The mobile phase was 2-methyl-2...
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PMID: 1806556
PDF is available here.
PDF is available here.
Journal of Chromatography A (586)1 1991
Abstract
Isolation of doxycycline, 6-epidoxycycline and 2-acetyl-2-decaboxamidometacycline from commercial metacycline was achieved by preparative column liquid chromatography on silica gel, previously impregnated with edetate (EDTA). Careful control of the pH of EDTA allowed fine tuning of the separation. T...
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PMID: 1666895
PDF is available here.
PDF is available here.
Abstract
An examination of 163 females suffering from habitual miscarriage revealed chlamydia in 41.7%. The miscarriage rate was 59.1% inChlamydia infection. All the females recovered from Chlamydia infection delivered in term. Antichlamydial agents should be supplemented as part of combined therapy of habit...
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PMID: 1951968
PDF is available here.
PDF is available here.
Abstract
A thin-layer chromatographic (TLC) method involving UV and fluorescence densitometry is described for the assay and purity control of metacycline. With a mobile phase dichloromethane-methanol-water (58:35:7, v/v/v) and a silica gel thin-layer, previously sprayed with 10% sodium edetate solution adju...
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PMID: 1821148
PDF is available here.
PDF is available here.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] / Ministerstvo meditsinskoi i mikrobiologicheskoi promyshlennosti SSSR (35)9 1990
Abstract
Antibiotic binding by leukocytes from patients with chronic brucellosis was studied in vitro. The pathogens were located intracellularly. The specimens were collected during the disease aggravation prior to the treatment and at the beginning of the remission after the routine therapy. It was found t...
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PMID: 2275592
PDF is available here.
PDF is available here.
Abstract
Sixty-nine patients suffering from acute necrotic cutaneous leishmaniasis have been effectively treated with methacycline, 60 ones with doxycycline. Many parameters of these drug's efficacies are similar to those of monomycin, the most active drug for cutaneous leishmaniasis. Therapy with the afore-...
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PMID: 2741550
PDF is available here.
PDF is available here.
Abstract
Abstract
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology / Ministerstvo meditsinskoi promyshlennosti SSSR (32)10 1987
Abstract
It was shown that combined use of the polyene antibiotic amphoglucamine (AMG) and 5-fluorocytosine (5-FC), rifampicin, or methacycline was much more efficient in therapy of experimental generalized candidiasis. Combination of AMG with 5-FC or rifampicin proved to be the most favourable. The use of t...
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PMID: 3426181
PDF is available here.
PDF is available here.
Vutreshni bolesti (26)6 1987
Abstract
A case of a male patient with bronchopneumonia incorrectly treated for a long time with methacycline (rondomycin), an oxytetracycline drug, is reported. methacycline was applied in a dose of 8 capsules daily (2 capsules 4 times) in the course of 2 1/2 months, the total dose amounting to about 150 g....
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PMID: 3439145
PDF is available here.
PDF is available here.
Abstract
Archives of Dermatology (122)1 1986
Abstract
Pediatria Polska (60)6 1985
Abstract
Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology / Ministerstvo meditsinskoi promyshlennosti SSSR (30)3 1985
Abstract
Interaction of rabbit alveolar macrophages with morphocycline, tetracycline and methacycline was studied. The use of the membrane microfiltration technique in investigation of the antibiotic absorption by the macrophages provided description of the time course of the drug interaction with the cells...
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PMID: 3160300
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Antibiotiki (29)3 1984
Abstract
The combined effect of amphotericin B, a polyene antibiotic, and metacycline, a tetracycline antibiotic, on the cells of C. albicans was studied. The method of square titration followed by quantitative plating of the samples was used for estimation of the combination efficiency. An attempt was also...
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PMID: 6375550
PDF is available here.
PDF is available here.
Antibiotiki (28)9 1983
Abstract
Bioavailability of methacycline capsules manufactured by two different firms was studied and it was shown that they had statistically significant differences. Conditions for investigation of the rate of methacycline transfer from the pharmaceutical form into solution were developed with the use of a...
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PMID: 6638980
PDF is available here.
PDF is available here.
Abstract
Abstract
Drug induced esophageal ulcers are more frequent than supposed. Four ulcerative lesions of the esophagus, two after ingestion of doxycycline-hydrochloride, one after metacycline-hydrochloride, and one after emeproniumbromide were detected at the department of Internal Medicine of a medium-sized stan...
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PMID: 7157902
PDF is available here.
PDF is available here.
Abstract
Abstract
Antibiotiki (25)5 1980
Abstract
Complex formation of metacycline (Pv) with beryllium, aluminium, magnesium, calcium and zinc ions in aqueous solutions was studied fluorometrically. The antibiotic formed the following compounds: CaPv2 (pH 9.45), MgPv (pH 10.40), Be Pv (pH 7.0 and 11), Ca Pv (pH 13.5), Zn Pv (pH 7.15) and Al Pv (pH...
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PMID: 7387127
PDF is available here.
PDF is available here.
Abstract
Abstract
A five-year follow-up is presented of a unique material of patients who acquired a greyish black hyperpigmentation during long-term methacycline therapy for chronic bronchitis. The melanosis disappeared in cases in which tetracycline therapy was discontinued during the observation period but not in...
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PMID: 6162334
PDF is available here.
PDF is available here.
Abstract
Abstract
Antibiotiki (24)8 1979
Abstract
Desintegration and dissolution of capsules and tablets of methacycline hydrochloride were studied. The study on solubility of methacycline hydrochliride capsules filled with methacycline granulate or powder according to the same formula showed that the rate of the antibiotic liberation from the caps...
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PMID: 485108
PDF is available here.
PDF is available here.
Abstract
Abstract
The author reports a 50-year-old woman with haemorrhagic lesion to the sciatic nerve during a chronic infectious process and treatment with chemotherapeutic agents. The nerve was damaged by pressure exerted by extravasated blood or haemorrhage from vasa nervorum.
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PMID: 224332
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Studies of flexible plates made of plastic have shown that less osteoporosis develops beneath them than beneath rigid metal plates. However, to date plastic plates of appropriate physical properties and biocompatibility are not available for use in humans. To determine if a similar beneficial effect...
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PMID: 100500
PDF is available here.
PDF is available here.
Abstract
Antibiotiki (23)6 1978
Abstract
The acute toxicity parameters of oxytetracycline and its semisynthetic derivatives was determined on laboratory animals of various species. The three antibiotics were described as belonging to the group of low toxic compounds according to the classification adopted in industrial toxicology. However,...
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PMID: 677841
PDF is available here.
PDF is available here.
Abstract
This paper describes the high performance liquid chromatographic (HPLC) analysis of eight parent tetracycline standards: tetracycline, chlortetracycline, rolitetracycline, oxitetracycline, minocycline, doxycycline, democlocycline, methacycline; and three tetracycline epimers: epitetracycline, epianh...
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PMID: 641134
PDF is available here.
PDF is available here.
L' Information dentaire (60)7 1978
Abstract