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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Naphthalenes (17):
Recent article
Naphthalenes
Transplantation (92)8 2011
Abstract
We examined 10 stable kidney transplant patients (mean estimated glomerular filtration rate 51±10 mL/min/1.73 m(2)) who received cinacalcet daily for persistent hyperparathyroidism. Urine specimens were collected at baseline and every 2 hr for a total study period of 6 hr after ingestion of 30 mg c...
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PMID: 21876476
PDF is available here.
PDF is available here.
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Abstract
Abstract
BINOL-derived phosphoric acids have emerged during the last five years as powerful chiral Brønsted acid catalysts in many enantioselective processes. The most successful transformations carried out with chiral BINOL phosphates include C-C bond formation reactions. The recent advances have been revi...
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PMID: 20820680
PDF is available here.
PDF is available here.
Critical Care Medicine (38)12 2010
Abstract
Critical Care Medicine (38)12 2010
Abstract
To investigate whether hypothermia could be induced pharmacologically after resuscitation with the cannabinoid CB1/CB2 receptor agonist in a rat model and its effects on outcomes of cardiopulmonary resuscitation.
Prospective, randomized, placebo-controlled experimental study.
University-affiliated a...
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PMID: 20890199
PDF is available here.
PDF is available here.
Clinical Nephrology (74)6 2010
Abstract
We prospectively studied renal transplant recipients with secondary hyperparathyroidism who were receiving cinacalcet before transplantation and continued treatment afterwards (n = 29) at a dose of 30 mg/day. Cinacalcet dose was titrated to serum calcium. Patients were followed for 6 months. Inciden...
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PMID: 21084046
PDF is available here.
PDF is available here.
Anesthesiology (113)6 2010
Abstract
Although hypoxic late preconditioning (LPC) limits ischemia-reperfusion injury in vitro, its cardioprotective effect is not established in vivo.
In part 1, rats were exposed to 4 h of hypoxia (16%, 12%, 8% oxygen) before 24 h of reoxygenation. In part 2, normoxic rats received early preconditioning...
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PMID: 21068657
PDF is available here.
PDF is available here.
Environmental Pollution (158)11 2010
Abstract
The influence of PAH chemical structure and concentration, added in either single (75 or 300 mg kg(-1)) or multiple (2 × 75, 2 × 150 or 4 × 75 mg kg(-1)) applications as single- or multiple-contaminant systems, on the development of PAH biodegradation in a pristine soil was investigated. Developm...
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PMID: 20801563
PDF is available here.
PDF is available here.
Arthritis & Rheumatism (62)11 2010
Abstract
The activity of p38 MAPK regulates lipopolysaccharide (LPS)-stimulated production of key proinflammatory cytokines such as tumor necrosis factor α (TNFα). Consequently, p38 MAPK inhibitors have attracted considerable interest as potential treatments of rheumatoid arthritis (RA), and studies in mur...
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PMID: 20589681
PDF is available here.
PDF is available here.
Abstract
We show that non-muscle myosin heavy chain IIA (NMHC-IIA), a subunit of non-muscle myosin IIA (NM-IIA), functions as an HSV-1 entry receptor by interacting with gB. A cell line that is relatively resistant to HSV-1 infection became highly susceptible to infection by this virus when NMHC-IIA was over...
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PMID: 20944748
PDF is available here.
PDF is available here.
European Journal of Pharmacology (644)1-3 2010
Abstract
We have investigated the cardiovascular actions of thalidomide in vivo and in vitro. Blood pressure was recorded in pentobarbitone anaesthetized rats. Isometric contractions were examined in rings of rat tail artery and aorta. Radioligand binding studies of alpha(1A)- and alpha(1B)-adrenoceptor site...
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PMID: 20615401
PDF is available here.
PDF is available here.
Abstract
These results suggest that (1) ETS is a significant source of inhalation exposure to the carcinogen 1,3-butadiene and high molecular weight PAHs, many of which are carcinogenic, and (2) that for lower molecular weight PAHs such as naphthalene, exposure by routes other than inhalation predominate, si...
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PMID: 20591483
PDF is available here.
PDF is available here.
Abstract
We have evaluated a novel cannabinoid antagonist (AM6545) designed to have limited CNS penetration, to see if it would inhibit food intake in rodents, without aversive effects.
Cannabinoid receptor binding studies, cAMP assays, brain penetration studies and gastrointestinal motility studies were car...
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PMID: 20880401
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Abstract
The synthesis and Zn(2+) coordination properties of a new macrocycle (L1) obtained by dipodal (2 + 2) condensation of the polyamine 3-(naphthalen-2-ylmethyl)pentane-1,5-diamine with 1H-pyrazole-3,5-dicarbaldehyde are reported. pH-metric studies show that L1 bears five measurable protonation steps in...
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PMID: 20661509
PDF is available here.
PDF is available here.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (21)5 2010
Abstract
We studied its effect on 20 patients (13 males) on maintenance hemodialysis (HD), 80% of them have persistent high PTH levels (i.e. more than 80 pmol/L), the remaining patients had PTH levels more than 60 pmol/L. Five of 20 (25%) patients dropped out from the study (2 because of severe GIT upset, on...
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PMID: 20814122
PDF is available here.
PDF is available here.
Fitoterapia (81)6 2010
Abstract
From propolis samples from Kenya, two new arylnaphtalene lignans were isolated, tetrahydrojusticidin B 1 and 6-methoxydiphyllin 2, along with four known phenolic compounds 5-8, found for the first time in propolis. The structures of the compounds were elucidated based on their spectral properties. T...
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PMID: 20079813
PDF is available here.
PDF is available here.
Mycopathologia (170)3 2010
Abstract
Involvement of the nose and subcutaneous tissues of the face in Basidiobolomycosis is rare. The infection is more common in children, but the case presented here is an adult. Its occurrence in a native of North India is also uncommon. Previous studies have mostly reported good response to potassium...
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PMID: 20373026
PDF is available here.
PDF is available here.
Abstract
A prospective randomized controlled study was performed to compare the clinical effects of naftopidil and tamsulosin. Men complaining of lower urinary tract symptoms due to benign prostatic hyperplasia were randomized into two groups : one receiving 50mg naftopidil once daily (Naf group, n=36 patien...
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PMID: 20940522
PDF is available here.
PDF is available here.
Abstract
We used a series of molecules known to inactivate various elements of the pathway. W-7 prevents CaM from interacting with other molecules. Neomycin isolates PIP(2) from PLC. U-73122 directly inactivates PLC. 2-APB blocks IP(3) receptors which would otherwise cause release of Ca(2+). Verapamil and Cd...
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PMID: 20416320
PDF is available here.
PDF is available here.
Abstract
We evaluate the environmental literature on naphthalene published since 1990, drawing on nearly 150 studies that report emissions and concentrations in indoor, outdoor and personal air. While naphthalene is both a volatile organic compound and a polycyclic aromatic hydrocarbon, concentrations and ex...
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PMID: 20717549
PDF is available here.
PDF is available here.
Nature Chemistry (2)7 2010
Abstract
Nature Chemistry (2)7 2010
Abstract
We prepared a collection of monomeric, cyclic and rod-shaped naphthalenediimide transporters. Their ability to exert anion-pi interactions was demonstrated by electrospray tandem mass spectrometry in combination with theoretical calculations. To relate this structural evidence to transport activity...
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PMID: 20571570
PDF is available here.
PDF is available here.
FASEB Journal (24)7 2010
Abstract
We have capitalized on this phenomenon of nature to identify new gamma-secretase inhibitors. Here we show that 2-hydroxy naphthyl derivatives, a previously identified subclass of NAD(+) analog inhibitors of sirtuin 2 (SIRT2), are direct gamma-secretase inhibitors. Subsequent structure-activity relat...
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PMID: 20237298
PDF is available here.
PDF is available here.
Cell Calcium (48)1 2010
Abstract
We implicate a novel BEL-sensitive mechanism which regulates both SOCE and phenotype modulation, independently.
Copyright 2010 Elsevier Ltd. All rights reserved....
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PMID: 20619453
PDF is available here.
PDF is available here.
Abstract
IMPORTANCE OF THE FIELD: Premature ejaculation (PE) is a common male sexual disorder which is associated with substantial personal and interpersonal negative psychological factors. Drug treatment of PE with an off-label antidepressant selective serotonin reuptake inhibitor (SSRI) drug is common. The...
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PMID: 20540653
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to evaluate rheological properties and release of terbinafine (an antifungal drug) from chitosan hydrogels, and test some additives as possible solvents, preservatives and potential chemical penetration enhancers. The release of terbinafine was better from hydrogel with gly...
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PMID: 20662323
PDF is available here.
PDF is available here.
Urologia Internationalis (85)1 2010
Abstract
We examined the tolerability of dosage methods of naftopidil in the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH/male LUTS).
A total of 80 patients with BPH/male LUTS who had an International Prostate Symptom Score (IPSS) >or=8 and IPSS quality of...
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PMID: 20516676
PDF is available here.
PDF is available here.
Clinical calcium (20)7 2010
Abstract
It has been recognized that deranged mineral metabolism in CKD results not only in bone diseases but also in a higher risk of mortality, Accordingly, instead of the classic term "Renal Osteodystrophy (ROD) , "a new term, "CKD-Mineral and Bone Disorders (CKD-MBD), "has recently been proposed as a sys...
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PMID: 20585179
PDF is available here.
PDF is available here.
Clinical calcium (20)7 2010
Abstract
The final goal of CKD-MBD (chronic kidney disease, mineral and bone disorder) is to reduce the risk of death in uremic patients. To achieve this objective, it is of importance to manage laboratory abnormalities, bone abnormalities, and vascular calcification appropriately. Many observation studies s...
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PMID: 20585187
PDF is available here.
PDF is available here.
Clinical calcium (20)7 2010
Abstract
Cinacalcet, a calcium receptor modulator, reduces serum phosphate levels as well as parathyroid hormone (PTH) and serum calcium levels, and improve the control of mineral metabolic disorder, which is a major problem by the active vitamin D sterols in the treatment of secondary hyperparathyroidism. I...
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PMID: 20585188
PDF is available here.
PDF is available here.
Clinical calcium (20)7 2010
Abstract
We should expect more effective management of CKD-MBD, leading to the improvement of morbidity and mortality in this patient population. In this part, we consider indication of parathyroid interventions surround the present condition....
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PMID: 20585190
PDF is available here.
PDF is available here.
Abstract
We categorized the samples as: more smoke exposure (MSE), more dust exposure (MDE), less smoke exposure (LSE), and less dust exposure (LDE). Mean concentrations of PCDDs were 1070, 223, 3690, and 732 pg/g lipid wt, and mean concentrations of PCDFs were 910, 1520, 230, and 117 pg/g lipid wt, for the...
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PMID: 20455569
PDF is available here.
PDF is available here.
Abstract
This study investigated the efficacy of terutroban, a specific thromboxane/prostaglandin endoperoxide receptor antagonist, on stroke incidence in spontaneously hypertensive stroke-prone rats (SHRSP). The effects of terutroban were compared with those of aspirin, another antiplatelet...
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PMID: 20332187
PDF is available here.
PDF is available here.
Abstract
These results show that the discriminative stimulus effects of rimonabant in Delta(9)-THC-treated monkeys are a more pharmacologically selective measure of cannabinoid withdrawal than rimonabant-induced head shaking. These results suggest that cannabinoid and noncannabinoid (alpha(2)-adrenergic) ago...
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PMID: 20375197
PDF is available here.
PDF is available here.
Abstract
We tested WIN 55212-2 [(R)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de)-1,4-benzoxazin-6-yl]-1-napthalenylmethanone], a cannabinoid receptor agonist, and genetic deletion or pharmacological inhibition of FAAH in the lipopolysaccharide (LPS) mouse model of inflammatory pain. WIN...
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PMID: 20375198
PDF is available here.
PDF is available here.
Abstract
Science of the Total Environment (408)14 2010
Abstract
The aim of this work was to evaluate urinary benzene, toluene, ethylbenzene, m+p-xylene, o-xylene (BTEX), methyl tert-butyl ether (MTBE), ethyl tert-butyl ether (ETBE), and naphthalene (NAP) as biomarkers of exposure to environmental pollutants. Personal air and urine samples from 108 subjects belon...
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PMID: 20417546
PDF is available here.
PDF is available here.
Journal of Hazardous Materials (178)1-3 2010
Abstract
Carbon nanotubes (CNTs) exhausted with dye reactive red 3BS were regenerated by microwave irradiation under N(2) atmosphere. High regeneration efficiency was achieved and the regeneration efficiency reached 92.8% after four cycles regeneration. The decrease in adsorption capacity was suggested to be...
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PMID: 20153112
PDF is available here.
PDF is available here.
Journal of Hazardous Materials (178)1-3 2010
Abstract
The toxicity of naphthalene to Chlorella vulgaris was studied under nitrogen (N)-, phosphorus (P)-enriched and N,P-starved condition. Results showed that naphthalene was less toxic under N,P-starved condition. The inhibitory rates were less than 15.3% to C. vulgaris during 7 days exposure with the i...
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PMID: 20133058
PDF is available here.
PDF is available here.
Abstract
To determine pharmacokinetic parameters of orally administered terbinafine hydrochloride for potential treatment of aspergillosis in raptors, 10 adult red-tailed hawks (Buteo jamaicensis) were used in single dose trials by using 15, 30, and 60 mg/kg doses with a 2-week washout period between trials....
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PMID: 20806657
PDF is available here.
PDF is available here.
Pediatric Emergency Care (26)6 2010
Abstract
Medical Mycology (48)4 2010
Abstract
We report two cases of onychomycosis caused by Aspergillus persii, a recently described new Aspergillus species. After ten and three years respectively, both patients showed relapsing nail infections, and mycological tests were still positive for A. persii. In vitro antifungal susceptibility tests d...
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PMID: 20055738
PDF is available here.
PDF is available here.
Chemical Communications (46)20 2010
Abstract
A novel compound, (5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide), was prepared and characterized; it shows dual functional roles as an effective antitumor and a two-photon induced bio-imaging agent.
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PMID: 20379581
PDF is available here.
PDF is available here.
Abstract
The adsorption behavior of naphthalene onto naturally hydrophobic talc from aqueous solution was investigated in this study. The natural talc was first pretreated by sonication to improve the surface characteristics and enhance the uptake capacity by increasing the specific surface area (SSA) of tal...
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PMID: 20163977
PDF is available here.
PDF is available here.
Abstract
The results of this research confirm previous findings about the efficacy of terbinafine. The drug was shown to be highly effective to treat dermatophyte infections. The disk-diffusion method was easy to use and is a suitable technique for routine use in clinical laboratories....
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PMID: 20676465
PDF is available here.
PDF is available here.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia (145)3 2010
Abstract
Terbinafine, a synthetic antifungal of allylamine class, has fungicidal activity against dermatophytes, moulds and certain dimorphic fungi and fungistatic activity against Candida albicans. Following oral administration the terbinafine is absorbed rapidly (>70%) and reaches within 2 hours the peak p...
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PMID: 20461049
PDF is available here.
PDF is available here.
Melanoma Research (20)3 2010
Abstract
We tested the effect of PDBu and Ca dependent activation of PKC-alpha as well as treatment with the PKC-alpha inhibitors calphostin C and Go6976. Furthermore, we transfected siRNA targeted against PKC-alpha into human melanoma cells and performed time-lapse analysis of cell migration followed by wes...
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PMID: 20216103
PDF is available here.
PDF is available here.
Abstract
The role of sediment-living meiofauna, benthic invertebrates smaller than 1000 μm such as nematodes and ostracods, on the mineralization of naphthalene, a common polycyclic aromatic hydrocarbon (PAH) in marine sediments, was studied in microcosms using radiorespirometry. A method to extract live...
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PMID: 20463764
PDF is available here.
PDF is available here.
Abstract
By a strategy featuring perfluoroalkylation of the highly soluble intermediates and their further efficient transformations to target compounds, a versatile synthesis of core-perfluoroalkylated perylene diimides (PDIs) and naphthalene diimides (NDIs) was developed, and PDIs perfluoroalkylated at 1-p...
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PMID: 20364870
PDF is available here.
PDF is available here.
Brain research (1328) 2010
Abstract
We aim to see if diabetic hyperalgesia is related to changes in Transient Receptor Potential Vanilloid 1 (TRPV1) or Cannabinoid CB1 receptors of periaqueductal gray (PAG). Activation of glutamatergic projecting neurons in midbrain ventrolateral periaqueductal gray (VL-PAG) induces antinociception. A...
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PMID: 20211611
PDF is available here.
PDF is available here.
Neuropsychopharmacology (35)6 2010
Abstract
We generated a mouse with a disruption of GASP1. In wild-type mice, repeated administration of the cannabinoid agonist WIN55,212-2 promoted downregulation of CB1 receptor levels and concomitant tolerance to the effects of drug on antinociception, motor incoordination, and locomotor hypoactivity. In...
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PMID: 20164830
PDF is available here.
PDF is available here.
Abstract
We report a case of disseminated Scedosporium/Pseudallescheria infection due to Pseudallescheria boydii sensu stricto after lung transplantation in a patient with cystic fibrosis. Dissemination occurred under voriconazole. Despite surgery and combination therapy with voriconazole, caspofungin, and t...
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PMID: 20220160
PDF is available here.
PDF is available here.
Abstract
In this study we identified potential target proteins that may serve as markers closely associated with toxicity. The large differences in previously reported rates of naphthalene metabolism to water-soluble metabolites in dissected airways from mice and monkeys are not reflected in similar differen...
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PMID: 20435546
PDF is available here.
PDF is available here.
Biochemistry (New York) (75)5 2010
Abstract
The ability of Pseudomonas fluorescens 26K strain to utilize naphthalene at concentrations up to 600 mg/liter as the sole source of carbon and energy in mineral liquid media was shown. Using HPLC, TLC, and mass-spectrometry, the intermediates of naphthalene transformation by this strain were identif...
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PMID: 20632934
PDF is available here.
PDF is available here.
Abstract
Simple enantioselective routes to the two key intermediates shown above (at center) for the synthesis of laurenditerpenol have been developed using a Diels-Alder step and the same catalyst system for each.
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PMID: 20337419
PDF is available here.
PDF is available here.
Abstract
These results suggest that the HNBA vesicles may be developed as a continuous monitoring and implantable fluorescence vesicular sensor, which might be applied in the practical field.
(c) 2010 Elsevier B.V. All rights reserved....
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PMID: 20188967
PDF is available here.
PDF is available here.
Abstract
In this study, as a continuation of our research for new (arylalkyl)imidazole anticonvulsant compounds, the design, synthesis and anticonvulsant/antimicrobial activity evaluation of a series of 2-acetylnaphthalene derivatives have been described. Molecular design of the compounds has been based on t...
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PMID: 20363141
PDF is available here.
PDF is available here.