Welcome to the Pubget Medical Subject Headings (MeSH) browser.
Click on a topic or subtopic below to explore related papers. You'll find the most recent paper about the current MeSH term along with other related papers below.
Articles on Raclopride
Effects of intraaccumbens amphetamine on production of 50kHz vocalizations in three lines of selectively bred Long-Evans rats
Effects of direct injections of amphetamine into the shell of the nucleus accumbens were studied in three lines of Long-Evans rats, two of which had been selected for low and high rates of 50 kHz calls in adolescence in response to a standard social stimulation, and compared to resul...
Noninvasive visualization of human dopamine dynamics from PET images
We recently introduced strategies for extracting temporal patterns of brain dopamine fluctuations from dynamic positron emission tomography (PET) data using the tracer [11C]-raclopride. Each of our methods yields a collection of time-concentration curves for endogenous dopamine. Given a spatially de...
Dopamine D2 receptor occupancy by perospirone: a positron emission tomography study in patients with schizophrenia and healthy subjects.
Dopamine D(2) receptor occupancy in the temporal cortex of patients ranged from 39.6% to 83.8%. Especially, occupancy in two patients who took 16 mg of perospirone 2.5 h before PET was over 70%. Mean occupancy in the striatum of healthy subjects was 74.8% at 1.5 h, 60.1% at 8 h, and 31.9% at 25.5 h...
Alterations of central dopamine receptors before and after gastric bypass surgery.
Brain available dopamine D2 binding appears to increase following GBP. This preliminary finding needs to be replicated in a larger population but suggests that diminished D2 binding in the obese may be due to D2 receptor downregulation. Changes in available dopamine receptor binding may play an impo...
Gap-filling for the high-resolution PET sinograms with a dedicated DCT-domain filter.
We aim to compensate the sinograms for the missing parts, i.e., gaps. For the gap filling, we propose an iterative discrete-cosine transform (DCT) domain method with two versions: 1) with basic DCT domain filter and 2) with dedicated and gap-dependent DCT domain filter. For the testing of the method...
Dopamine receptor antagonists impair place conditioning after acute stress in rats.
We recently showed conditioned place preference (CPP) induced by the acute application of a stressor such as being placed on an elevated stand or immobilized in a restraint holder. This study tested whether dopamine is involved in such CPP. The selective dopamine D1 and D2 receptor antagonists, SCH2...
Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.
We investigated in the mouse, a species suited for transgenic studies, the mechanisms of locomotor sensitization showed by the increased response to a second injection of drug (two-injection protocol of sensitization, TIPS). The first cocaine injection induced a locomotor sensitization that was comp...
Risperidone treatment increases CB1 receptor binding in rat brain.
No difference in body weight gained during treatment was observed between risperidone and vehicle treated rats, but plasma risperidone levels positively correlated with visceral fat mass. Risperidone treatment increased CB(1) receptor binding in the arcuate nucleus (40%), hippocampus (25-30%) and am...
Dopamine D1 and D2 antagonist effects on response likelihood and duration.
We investigated the dopamine receptor subtypes involved in regulating these two aspects of behavior. We examined the effects of D1 family (D1/D5) antagonist R(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (SCH23390; 0, 0.04, 0.08, or 0.16 mg/kg) and D2/D3...
Estradiol and song affect female zebra finch behavior independent of dopamine in the striatum
Female songbirds display preferences for certain song characteristics, but the neural and hormonal mechanisms mediating these preferences are not fully clear. The present study sought to further explore the role of estradiol, as well as assess potential roles of dopaminergic systems,...