Advanced search×

Welcome to the Pubget Medical Subject Headings (MeSH) browser.

Click on a topic or subtopic below to explore related papers. You'll find the most recent paper about the current MeSH term along with other related papers below.

All › Organic Chemicals › Hydrocarbons › Terpenes › Polyisoprenyl Phosphates

Polyisoprenyl Phosphates (2)

Articles on Polyisoprenyl Phosphates

  1. Computational identification of sweet wormwood (Artemisia annua) microRNA and their mRNA targets.
    Alok A Pani, Rajani Kanta RK Mahapatra, ... Pradeep Kumar PK Naik

    Genomics Proteomics Bioinformatics 9(6):200-10 (2011) PMID 22289476

    We used previously known miRNAs from Arabidopsis and rice against expressed sequence tag (EST) database of A. annua to search for potential miRNAs and their targets in A. annua. A total of six potential miRNAs were predicted, which belong to the miR414 and miR1310 families. Furthermore, eight potent...
  2. Donor simvastatin treatment abolishes rat cardiac allograft ischemia/reperfusion injury and chronic rejection through microvascular protecti...
    Raimo R Tuuminen, Simo S Syrjälä, ... Karl B KB Lemström

    Circulation 124(10):1138-50 (2011) PMID 21844074

    We report that rat cardiac allograft ischemia/reperfusion injury resulted in profound microvascular dysfunction that was prevented by donor treatment with peroral single-dose simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase and Rho GTPase inhibitor, 2 hours before graft procurement. Du...
  3. Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate.
    Brian M Wasko, Amel Dudakovic, and Raymond J Hohl

    J Pharmacol Exp Ther 337(2):540-6 (2011) PMID 21335425

    We hypothesized that inhibition of farnesyl diphosphate synthase (FDPS) and geranylgeranyl diphosphate synthase (GGDPS) by bisphosphonates would induce autophagy by depleting cellular geranylgeranyl diphosphate (GGPP) and impairing protein geranylgeranylation. Herein, we show that an inhibitor of FD...
  4. [Lactobacillus plantarum and phosprenyl competitively distinguish ovalbumin oligomannoside n-glycan].
    S M SM Sobolev, T N TN Nikolaeva, ... A V AV Pronin

    Zh Mikrobiol Epidemiol Immunobiol (2011) PMID 22308726

    Demonstration of the ability of native products of lactobacteria to bind mannose containing N-glycans as a display of one of the mechanisms of probiotic behavior of these symbiont microorganism in gastrointestinal tract (GIT). Lactobacillus plantarum 30 grown on selec...
  5. Analysis of protein prenylation in vitro and in vivo using functionalized phosphoisoprenoids.
    Uyen T T Nguyen, Yaowen Wu, ... Kirill Alexandrov

    Curr Protoc Protein Sci (2010) PMID 21104984

    I (GGTase I), and Rab geranylgeranyl transferase (also termed geranylgeranyltransferase type II - GGTase II). In this unit, synthetic isoprenoids conjugated to either a fluorophore or biotin group are used to assay the activity of protein prenyltransferases in vitro or to affinity tag prenylatable p...
  6. Quantum chemical dissection of the classic terpinyl/pinyl/bornyl/camphyl cation conundrum-the role of pyrophosphate in manipulating pathways...
    Young J Hong and Dean J Tantillo

    Org Biomol Chem 8(20):4589-600 (2010) PMID 20725661

    Based on quantum chemical studies, mechanisms to form bornyl diphosphate from geranyl diphosphate are suggested. While bornyl diphosphate is usually proposed to be generated via combination of the pyrophosphate group with a secondary bornyl cation, quantum chemical computations indicate that the bor...
  7. Molecular characterization of the cis-prenyltransferase of Giardia lamblia.
    Kariona A Grabińska, Jike Cui, ... John Samuelson

    Glycobiology 20(7):824-32 (2010) PMID 20308470

    We wondered how Giardia synthesizes dolichol phosphate (Dol-P), which is used to make N-glycans and glycosylphosphatidylinositol (GPI) anchors. Here we show that cultured Giardia makes an unsaturated polyprenyl pyrophosphate (dehydrodolichol), which contains 11 and 12 isoprene units and is reduced t...
    View PDF
  8. Total synthesis: towards artificial terpene cyclases.
    Matthieu M Willot and Mathias M Christmann

    Nat Chem 2(7):519-20 (2010) PMID 20571563

  9. Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isom...
    Fernando Lopez-Gallego, Sean A Agger, ... Claudia Schmidt-Dannert

    Chembiochem 11(8):1093-106 (2010) PMID 20419721

    Sesquiterpene synthases catalyze with different catalytic fidelity the cyclization of farnesyl pyrophosphate (FPP) into hundreds of known compounds with diverse structures and stereochemistries. Two sesquiterpene synthases, Cop4 and Cop6, were previously isolated from Coprinus cinere...
  10. Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
    S Kato, S Smalley, ... M Cuello

    J Cell Mol Med 14(5):1180-93 (2010) PMID 19432822