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All › Organic Chemicals › Amidines › Benzamidines › Diminazene

Diminazene (0)

      Articles on Diminazene

      1. Validation of an HPLC method for the simultaneous determination of diminazene diaceturate and phenazone in injectable veterinary granules an...
        Lantider L Kassaye, Ariaya A Hymete, ... Getachew G Genete

        Pak J Pharm Sci 25(1):255-9 (2012) PMID 22186338

        A validated HPLC method for the simultaneous determination of diminazene diaceturate and phenazone has been established for the analysis of the compounds in veterinary granules for injection and in bulk powders. The compounds were separated using a Symmetry RP 18 analytical column an...
      2. The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Tryp...
        V U VU Omoja, A O AO Anaga, ... S M SM Anika

        Asian Pac J Trop Med 4(5):337-41 (2011) PMID 21771672

        To investigate the effects of combination therapy of methanolic leaf extract of Azadirachta indica (A. indica) and diminazene diaceturate (DDA) in the treatment of experimental Trypanosoma brucei brucei (T. brucei brucei) infection in rats. Acute toxicity study of the...
      3. Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro.
        Shiang-Jyi SJ Hwang, Masahiro M Yamasaki, ... Mitsuyoshi M Takiguchi

        J Vet Med Sci 72(6):765-71 (2010) PMID 20160418

        We attempted to develop a strain of Babesia gibsoni resistant to diminazene aceturate (DA), an anti-babesial drug, in vitro. Since the DA-sensitive B. gibsoni strain could survive and proliferate in culture medium containing 1 ng/m l DA, the concentration of DA was gradually increased from 1 to 200...
      4. Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.
        Mhairi L ML Stewart, Richard J S RJ Burchmore, ... Michael P MP Barrett

        Eukaryot Cell 9(2):336-43 (2010) PMID 19966032

      5. The intravenous pharmacokinetics of diminazene in healthy dogs.
        V V Naidoo, M S G MS Mulders, and G E GE Swan

        J S Afr Vet Assoc 80(4):215-9 (2009) PMID 20458860

        Diminazene remains one of South Africa's most commonly used antiprotozoal agents for the management of babesiosis in dogs. Although the drug has been on the market for over 40 years, its intravenous pharmacokinetics are poorly known. To better understand the pharmacokinetics of the drug Berenil, it...
      6. Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia
        Vincent Delespaux, Hunduma Dinka, ... Stanny Geerts

        Drug Resist Updat 11(6):5 (2008) PMID 18993109

        Two groups of Trypanosoma congolense isolates collected from cattle in 1996 (n = 39) and 2003 (n = 38) in the Eastern Province of Zambia were analyzed by BclI-PCR-RFLP to assess the evolution of diminazene aceturate (DA) resistance over a period of seven years. The results show a significant increase...
      7. Preparation of polyclonal antibodies to diminazene and its detection in animal blood plasma
        S A SA Staroverov, O A OA Vasilenko, ... L A LA Dykman

        Int Immunopharmacol 8(10):5 (2008) PMID 18573353

        This work was undertaken to examine the possibility of preparing polyclonal antibodies to diminazene by using colloidal gold nanoparticles as an antigen carrier and adjuvant. The antibodies prepared by us were used for immunodot determination of diminazene in calf-blood plasma. The immunochemical re...
      8. Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses.
        Hamad Bin HB Rashid, Mamoona M Chaudhry, ... Asim Khalid AK Mahmood

        Trop Anim Health Prod 40(6):463-7 (2008) PMID 18575975

        The present work was conducted to study the comparative efficacy of two anti-protozoan (babesicidal) drugs on the recovery and health of horses. A total of 80 horses, showing typical clinical symptoms of the disease, were selected for this study; the presence of babesiosis was confirmed through bloo...
      9. Enhancement of hydrophilic drug loading and release characteristics through micellization with new carboxymethyldextran-PEG block copolymers...
        Ghareb Mohamed Soliman and Françoise M Winnik

        Int J Pharm 356(1-2):11 (2008) PMID 18242897

        The micellization of a model cationic drug, diminazene diaceturate (DIM) and a series of new diblock copolymers, carboxymethyldextran-poly(ethylene glycols) (CMD-PEG), were evaluated as a function of the ionic charge density or degree of substitution (DS) of the carboxymethyldextran block and the mo...
      10. Assessment of the occurrence of trypanocidal drug resistance in trypanosomes of naturally infected cattle in the Adamaoua region of Cameroon...
        A A Mamoudou, V V Delespaux, ... S S Geerts

        Acta Trop 106(2):4 (2008) PMID 18355771

        From May to November 2005, a study was carried out to assess the occurrence of trypanocidal drug resistance (DR) in trypanosomes of naturally infected cattle of the Adamaoua region of Cameroon. Two distinct Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) procedures were...