Abstract
We argue a shift from narrow single-disease approaches to malaria during pregnancy is required and document women's concerns about exposure to multiple vulnerabilities during pregnancy, including witchcraft, extramarital affairs, and multiple dangerous illnesses. Four dimensions are implicated in Ya...
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PMID: 20949843
PDF is available here.
Abstract
We investigated helminth parasitism in 2 South American rodent species, Ctenomys australis and C. talarum (Octodontidae), to determine whether the unusual solitary and subterranean nature of these hosts would impact their patterns of infection. We applied generalized linear models to infection data...
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PMID: 20500917
PDF is available here.
Abstract
The aim of the study was to identify risk factors for Toxoplasma gondii infection in pregnant women in FYR of Macedonia. Retrospective analysis of serological and epidemiological data in a series of 235 pregnant women from Macedonia, tested for Toxoplasma infection between January 2004 and December...
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PMID: 21073139
PDF is available here.
Abstract
Known for a century, Toxoplasma gondii has been studied in Serbia half this time, ever since the introduction of the Sabin-Feldman test at the Institute for Medical Research (IMR) in 1959. However, despite 50 years of continuous efforts, exact data on the frequency of acute clinical disease, acute i...
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PMID: 21073140
PDF is available here.
Abstract
Chagas disease is caused by the protozoan Trypanosoma cruzi and is an endemic zoonosis in the American continent. Thanks to the successful implementation of national programs for reducing the vectorial infestation and the strict control of blood-borne transmission of Chagas disease, the relative imp...
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PMID: 20695749
PDF is available here.
Abstract
Congenital malaria was documented in 13.6% of babies at delivery. Jaundice, irritability and poor feeding were most common symptoms associated with congenital malaria. Irritability and poor feeding had positive predictive values (PPV) of 100% on Day 14. CONCLUSION: Babies who present with poor feedi...
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PMID: 20499743
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Abstract
OBJECTIVE: To determine the factors affecting utilization of ITN by pregnant women in Etsako West LGA, Edo State. METHODOLOGY: A descriptive cross-sectional study design was employed. Using a systematic sampling method, a total of 385 respondents were selected from all ANC facilities in the LGA foll...
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PMID: 20499745
PDF is available here.
Abstract
A total of 179 pregnant women were studied. Almost 50.8% were between the ages of 25-30 years, 70.8% of the patients studied, had tertiary education. An assessment of the patients' status to anti-toxoplasmosis IgG showed 40.8% were positive while 59.2% were negative. Pet-keeping was a practice among...
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PMID: 20539334
PDF is available here.
Abstract
Among 4760 singleton deliveries, there were 103 stillbirths, yielding a stillbirth rate of 22 per 1000 deliveries. Over half (52.4%) of these stillbirths were macerated stillbirths. Maternal sociodemographic characteristics were not associated with stillbirth, while a history of maternal malaria in...
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PMID: 20096832
PDF is available here.
Abstract
Intermittent preventive treatment (IPT) against malaria is a malaria control strategy aimed at reducing the burden of malaria in certain high-risk groups, namely pregnant women and children. Three strategies - IPT in pregnancy (IPTp), infants (IPTi) and children (IPTc) - are reviewed here focusing o...
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PMID: 20455687
PDF is available here.
Abstract
Microfilariae were detected in 14 cases (11.8%), whereas the Og4C3 assay could detect filarial antigen in 44.5% of pregnant mothers. Interestingly, 24.5% of samples born from CFA-positive mothers were found positive for CFA. None of the cord samples from CFA-negative mothers were found positive for...
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PMID: 19849889
PDF is available here.
Abstract
We report the occurrence of congenital toxoplasmosis in three infants born to HIV infected women who had high anti-toxoplasma IgG and negative IgM during pregnancy. We briefly reviewed available literature and discussed the possible transmission mechanisms of congenital toxoplasmosis among HIV infec...
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PMID: 20563448
PDF is available here.
U M Chukwuocha,
I N S Dozie,
C O E Onwuliri,
C N Ukaga,
B E B Nwoke,
B O Nwankwo,
E A Nwoke,
J C Nwaokoro,
K S Nwoga,
O G Udujih,
C C Iwuala,
E T Ohaji,
O M Morakinyo and
B C Adindu
Abstract
This study aimed at assessing perceptions on use of ITNs in parts of the Imo River Basin, Nigeria and its implications in preventing malaria in pregnancy. Data was collected using focus group discussions, key informant interviews and structured questionnaires. Results showed high awareness on the be...
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PMID: 20695144
PDF is available here.
Abstract
Toxoplasma gondii, parvovirus B19 and cytomegalovirus cause most of the non-bacterial infections of the fetus. These infections are complicated by the fact that maternal toxoplasma and cytomegalovirus infections are almost always symptomless, which is often the case for parvovirus infections as well...
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PMID: 20405601
PDF is available here.
Abstract
In the global context of a reduction of under-five mortality, neonatal mortality is an increasingly relevant component of this mortality. Malaria in pregnancy may affect neonatal survival, though no strong evidence exists to support this association.
In the context of...
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PMID: 20195472
PDF is available here.
Abstract
Pregnant women assessed their knowledge of toxoplasmosis as least adequate, whereas midwifes, as most adequate. Pregnant women's knowledge about toxoplasmosis is poor. The group of physicians and medical students yielded evidently better score than pregnant women. There is a need for the improvement...
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PMID: 20677426
PDF is available here.
Nelly J Yatich,
Ellen Funkhouser,
John E Ehiri,
Tsiri Agbenyega,
Jonathan K Stiles,
Julian C Rayner,
Archer Turpin,
William O Ellis,
Yi Jiang,
Jonathan H Williams,
Evans Afriyie-Gwayu,
Timothy Phillips and
Pauline E Jolly
Abstract
The stillbirth rate was relatively high in this population (5%). Most of the stillbirths were fresh and 24% were macerated. When compared to women with no malaria, women with malaria had increased risk of stillbirth (OR = 1.9, 95% CI = 1.2-9.3). Other factors associated with stillbirth were severe a...
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PMID: 20379355
PDF is available here.
Abstract
We observed 173 male and 452 female patients. Seroprevalence in general population of Vojvodina was 38.1%. In male population seroprevalence was 45.7%, and in female population it was 35.2%, the difference which was statistically significant (p < 0.05). Seroprevalence increased with age and seroconv...
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PMID: 20607979
PDF is available here.
Abstract
Hydatid cystic disease is a parasitic disease primarily infesting the sheep and cattle. It is a rare condition in pregnancy with an incidence of 1/20000 pregnancies. An eighteen-year-old primigravida was evaluated due to obstructed labor. Multiple abdominal and pelvic hydatid cysts were diagnosed by...
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PMID: 21033629
PDF is available here.
Abstract
The incidences of reproductive disorders in bovine are increasing over years. This scenario is further aggravating due to more emphasis on selection and rearing of animal for specific commercial purposes which compromises livestock reproduction. Reproductive disorders like infertility and abortions...
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PMID: 20629218
PDF is available here.
Abstract
An 8-month-old boy was diagnosed with visceral leishmaniasis in the Ukraine, a non-endemic area. His mother had been treated for visceral leishmaniasis at 28-32 weeks gestation whilst working in Alicante, Spain and delivered her infant at 38 weeks gestation by elective caesarean section in Ukraine....
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PMID: 20522305
PDF is available here.
Abstract
Anti-Trypanosoma cruzi antibodies in the umbilical cord of 351 parturients in the city of Pelotas, Rio Grande do Sul were investigated to determine the prevalence of Chagas disease among pregnant women. One case was identified (0.3%), without detection of congenital transmission. This highlights the...
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PMID: 20209365
PDF is available here.
Abstract
Chagas disease, a parasitic infection with Trypanosoma cruzi, recently emerged in Europe and in Switzerland. Mother-to-child infection represents a major mode of transmission in non endemic areas. In 2008, 305 Latin American pregnant women consulting at the Geneva University Hospitals were screened...
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PMID: 19947451
PDF is available here.
Abstract
The nematode Enterobius vermicularis is normally found within the human gastrointestinal tract. Pregnant females migrate towards the anus to lay their eggs. During this nocturnal migration some worms find another adjacent orifices, most commonly the female genitourinary tract. The presented case is...
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PMID: 19902679
PDF is available here.
Abstract
We review the history of artemisinin discovery, discuss the mode of action and potential drug targets, and present strategies to elucidate resistance mechanisms....
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PMID: 19803708
PDF is available here.
Abstract
We discuss here how this burden has driven the natural selection of numerous polymorphisms in the genes encoding hemoglobin and other erythrocyte proteins and some effectors of immunity. Plasmodium falciparum, the most deadly parasite species in humans, displays a vigorous system of antigen variatio...
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PMID: 19729847
PDF is available here.
D Ouermi,
J Simpore,
A M G Belem,
D S Sanou,
D S Karou,
D Ilboudo,
C Bisseye,
S M Onadja,
V Pietra,
S Pignatelli,
C Gnoula,
J B Nikiema and
G B Kabre
Abstract
We found that HIV-seropositive status seem to be associated with great prevalence rates of both T. gondii (31.9 vs. 22.5%) and HBV (13.0 vs. 5.8%). The elevated co-infection rate in HIV-positive women suggested that they are exposed to T. gondii and HBV infections prevalently because of their immune...
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PMID: 19943453
PDF is available here.
Abstract
We investigated the tissue distribution of N. caninum in aborted bovine fetuses and dam blood samples by a nested PCR assay, and compared the nested PCR with ELISA in the diagnosis of N. caninum infection. In total, 26 aborted fetuses and 813 blood samples were collected from 8 dairy herds in Beijin...
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PMID: 19660160
PDF is available here.
Abstract
Parity was highly predictive of birth weight in the study subjects. Primigravidae and secondigravidae had a significantly lower mean birth weight (2952g) than women of higher gravidity (3214g) p-value <0.0001. Regardless of IPT administration, women who became positive for malaria infection at any p...
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PMID: 20575312
PDF is available here.
Abstract
We studied term sera from 1807 pregnancies in 1591 women for whom IgG status for cytomegalovirus, Epstein-Barr virus, herpes simplex virus type 1, herpes simplex virus type 2, and/or Toxoplasma gondii was available from prior analyses. We tested the sera (masked regarding infectious status) for auto...
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PMID: 19811261
PDF is available here.
Abstract
We tested the efficacy of azithromycin in reducing congenital transmission of T. gondii in the large vesper mouse, Calomys callosus, a rodent. Females of C callosus were inoculated perorally with 20 cysts of ME49 strain of T. gondii on the day of fertilization, and fetuses were collected from the 15...
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PMID: 20050006
PDF is available here.
Abstract
The present study assessed sensitivity and specificity of PCR targeting P30 gene in diagnosis of congenital toxoplasmosis using amniotic fluid samples. A total of 358 pregnant women in their first trimester of pregnancy, most of them were asymptomatic while the others suffered lymphadenopathy, fever...
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PMID: 19795760
PDF is available here.
Abstract
Congenital Toxoplasma gondii infection may lead to abortion, stillbirth, neonatal death as well as severe congenital toxoplasmosis in the newborn infants. No doubt, early and proper diagnosis of infection pregnant women or her baby pave the way to effective treatment and minimize complications. In t...
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PMID: 19795769
PDF is available here.
Abstract
This study was conducted between August 2007 and October 2008 to identify the sero-prevalence of Toxoplasma gondii among pregnant women of different ages and stages of gestation. Latex agglutination test was used as screening test. ELISA-IgG & IgM tests measured for the Toxo-Latex positive cases to...
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PMID: 19795746
PDF is available here.
Abstract
After controlling for gravidity and antimalarial treatment, higher levels of IgG to VSA-PAM were associated with decreased anemia at delivery (odds ratio [OR], 0.66 [95% confidence interval {CI}, 0.46-0.93]; P = .018) and were weakly associated with decreased parasitological failure (OR, 0.78 [95% C...
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PMID: 19500037
PDF is available here.
Abstract
Knowledge on malaria illness and ITNs was high with majority of pregnant women having adequate level of knowledge (86.9%). There was significant association between level of education and adequate knowledge (P-value = 0.010). Good attitude on ITNs use was low. There was no association between good a...
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PMID: 20499780
PDF is available here.
Abstract
We report a case of asymptomatic congenital toxoplasmosis following a periconceptional infection of the mother. Fetal infection is very uncommon in such a situation, and mostly associated with fetal damage. We recommend that newborns undergo postnatal screening, even after maternal periconceptional...
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PMID: 19561432
PDF is available here.
Abstract
We analysed the presence of atypical manifestations (vegetative, verrucous, crusted and lupoid) among a cohort of patients presenting to the Health Post of Corte de Pedra, Bahia, Brazil. Among 1396 patients diagnosed with ATL in 2005-2006, 35 patients (2.5%) presented with atypical manifestations of...
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PMID: 19481233
PDF is available here.
Abstract
About one-third 164 (36%) of the respondents were aware of ITN in malaria prevention, but less than a third 124 (27%) had ever used it and only 88 (19%) were currently using it, while 104 (23%) of the total respondents had a member of their household using ITN. Some of the difficulties encountered o...
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PMID: 19534367
PDF is available here.
Abstract
Co-infection with malaria and HIV in pregnant women is particularly common in sub-Saharan Africa and has serious consequences for both mother and newborn child. Numerous studies have been published on the effects in pregnancy of HIV on malaria infection and on the effects of malaria on HIV infection...
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PMID: 19460261
PDF is available here.
Abstract
In the absence of prompt and efficacious treatment, malaria patients may progress within a few hours from having minor symptoms to severe disease and death. These last years have seen the development of several artemisinin-based combinations, new treatments for severe malaria patients, and new strat...
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PMID: 19463069
PDF is available here.
Abstract
Infections caused by Toxoplasma gondii follow, in general, a mild or asymptomatic course. However, certain individuals, such as immunocompromised patients or those undergoing immunosuppressive therapy, pregnant women, newborns and patients with chorioretinitis, an ocular forms of toxoplasmosis, are...
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PMID: 19637138
PDF is available here.
Abstract
Response rate was 100%. Twenty nine percent prevalence of malaria parasitaemia was detected, more common among primigravidae. Women with higher parity had higher frequency of anaemia in pregnancy. More than half of the pregnant women (51%) were in their second trimester at the time of booking. There...
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PMID: 19764671
PDF is available here.
Abstract
We evaluated whether reduction of maternal parasitaemia before mating has beneficial effects on pregnancy outcome. Female mice were subjected to benznidazole (Bz) treatment after infection. On day 30 of therapy, mating was assessed and pregnancy outcome was determined on day 14 of gestation. Fetal r...
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PMID: 19366478
PDF is available here.
Abstract
We performed a secondary analysis of data from a clinical trial of antibiotics to reduce chorioamnionitis. Data regarding 1,662 HIV-1-infected women with live born singleton and first-born twin infants with information regarding PM and infant HIV-1 infection status at birth were analyzed. At the tim...
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PMID: 19346367
PDF is available here.
Abstract
Between June 2006 and October 2008, the safety of artemisinins during early human pregnancy was assessed in central-eastern Sudan. Pregnant women in the first or second trimester who were attending antenatal-care clinics at the Wad Medani, Gadarif and New Halfa hospitals were interviewed. Each was a...
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PMID: 19341535
PDF is available here.
Abstract
We concluded that high T. gondii-specific IgG values were much more frequent among HIV-infected pregnant women, but it did not translate into an increased risk of maternal-fetal transmission of toxoplasmosis....
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PMID: 18855029
PDF is available here.
Abstract
We hypothesized that it might aid in clearance of IE from the placenta, thereby reducing the risk of LBW babies. To test this hypothesis, molecular genotyping was used to detect polymorphisms at codon 57 (A/C) in exon 1 of MBL2 in 401 pregnant Cameroonian women, with or without placental malaria, wh...
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PMID: 19139195
PDF is available here.
Abstract
We indirectly exposed pregnant mice to infected neighbours by housing them next to non-contagious conspecifics infected with Babesia microti. We examined the effect of this indirect immunological exposure on both the females and their adult offspring. Exposed females had higher levels of serum corti...
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PMID: 19129100
PDF is available here.
Abstract
Malaria preventive strategies in pregnancy were assessed in a health center randomized trial comparing intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) with and without community based promotional activities in rural Burkina Faso. The study involved 2,240 secundigravidae an...
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PMID: 19270299
PDF is available here.
Abstract
We conducted a Delphi survey among experts to inquire as to their opinion on controversial issues regarding T. gondii risk factors, and we compared their position with that of a group of pregnant women in order to gather data for writing information guidelines on food safety during pregnancy. Betwee...
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PMID: 19343964
PDF is available here.