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Protozoan Infections (6):
Recent article
Protozoan Infections
Abstract
We evaluate the need for a holistic approach to address this issue and make recommendations for this cause.
Copyright © 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved....
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PMID: 20399129
PDF is available here.
PDF is available here.
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Abstract
To determine 1) the degree of soil contamination by parasites; 2) the prevalence of contaminated samples; 3) the overall number of parasitic forms, by distance between the collection site and the domicile; 4) the mean number of parasite forms per peri-household area; and 5) the variables associated...
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PMID: 20721441
PDF is available here.
PDF is available here.
Medicina Clínica (134)10 2010
Abstract
We examine current data on the role of iron in the struggle between host and pathogen to regulate levels of this essential element. We hope that, in the near future, treatments aimed at reducing iron overload will improve the response to current therapies, and help control infection.
Copyright 2009...
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PMID: 20044111
PDF is available here.
PDF is available here.
Abstract
This study evaluates the effects of retinol on intestinal barrier function, growth, total parasites, and Giardia spp infections in children in northeastern Brazil.
The study was a double-blind, randomized placebo-controlled trial (http://clinicaltrials.gov; register no. #NCT00133406) involving 79 ch...
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PMID: 20038852
PDF is available here.
PDF is available here.
Epidemiology and Infection (138)3 2010
Abstract
These results confirm previous findings and provide several new hypotheses on the effects of hygiene and water management on H. meleagridis and histomoniasis....
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PMID: 19664306
PDF is available here.
PDF is available here.
Acta Cytologica (54)4 2010
Abstract
Abstract
Since human intestinal parasitic infections are high in the study area, mass treatment of people with intestinal protozoans is strongly recommended, especially in the rural areas where the prevalence was very high....
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PMID: 20130377
PDF is available here.
PDF is available here.
Abstract
We need to treat increasing number of patients showing symptoms of such diseases. Unfortunately, the array of available and efficient antiparasitic drugs has been shrinking. Their efficacy decreases and quite often the side effects are serious. In this paper we would like to focus on a new promising...
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PMID: 20450003
PDF is available here.
PDF is available here.
Abstract
Abstract
We reviewed the current knowledge about DNA repair mechanisms in the most relevant human protozoan pathogens. Additionally, we described the recent advances to understand DNA repair mechanisms in Entamoeba histolytica with special emphasis in the use of genomic approaches based on bioinformatic anal...
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PMID: 19591963
PDF is available here.
PDF is available here.
Abstract
We evaluated the prevalence of enteroparasitosis in tuberculosis patients, HIV-infected and non HIV infected, and we observed the influence of helminth presence in the response to tuberculin skin test (TST) and tuberculosis clinical outcomes. From 607 clinical records reviewed, 327 individuals met t...
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PMID: 20464334
PDF is available here.
PDF is available here.
Abstract
Nitric oxide (NO) is a potent mediator with diverse roles in regulating cellular functions and signaling pathways. The NO synthase (NOS) enzyme family consists of three major isoforms, which convey variety of messages between cells, including signals for vasorelaxation, neurotransmission and cytotox...
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PMID: 20464336
PDF is available here.
PDF is available here.
Preventive Veterinary Medicine (91)2-4 2009
Abstract
Factors associated with parasitism by helminths and protozoans in 500 dogs presented to three veterinary clinics in the municipality of Rio de Janeiro from November 2003 to September 2004 were evaluated. Dogs were submitted to physical examination and owners were interviewed about the animal's manag...
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PMID: 19577316
PDF is available here.
PDF is available here.
Parasitology (93 ( Pt 2))02 2009
Abstract
Four common blood parasites belonging to the genera Babesia, Hepatozoon, Trypanosoma and Grahamella were detected in sympatric populations of Clethrionomys glareolus and Apodemus sylvaticus. Seasonal changes in the abundance of hosts and parasites were monitored in a longitudinal field survey for 18...
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PMID: 3537923
PDF is available here.
PDF is available here.
Parasitology (93 ( Pt 2))02 2009
Abstract
Changes in the response of black mollies Poecilia latipinna to infection with Ichthyophthirius multifiliis subsequent to single I. multifiliis infections were examined experimentally. Incomplete resistance to infection was established, the degree of which did not depend on the intensity of the initi...
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PMID: 3097601
PDF is available here.
PDF is available here.
Sexual Health (6)3 2009
Abstract
Direct oral-anal sexual contact is a common practice among men who have sex with men (MSM) and is implicated in the transmission of various enteric pathogens including intestinal parasites. The present study reviewed data on the sexual transmission of intestinal parasites among MSM, and highlighted...
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PMID: 19653954
PDF is available here.
PDF is available here.
Hepatitis temporally associated with an herbal supplement containing artemisinin - Washington, 2008.
Abstract
Artemisinins are a class of compounds that include artesunate, artemether, and artemisinin and have potent antimalarial activity. In combination with other drugs (artemisinin combination therapy), these compounds are the first-line treatment recommended by the World Health Organization for Plasmodiu...
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PMID: 19680221
PDF is available here.
PDF is available here.
Parasitology (85 (Pt 1))01 2009
Abstract
In mice infected with the intestinal flagellates Giardia muris or Spironucleus muris, together with the blood parasites Babesia microti or Plasmodium yoelii, there is a temporary decrease of flagellate cyst output coincident with the peak of the blood parasite infections, followed by a rapid return...
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PMID: 6214756
PDF is available here.
PDF is available here.
Parasitology (85 (Pt 1))01 2009
Abstract
The intestinal flagellates, Giardia muris and Spironucleus muris, cause similar infections in CBA mice as determined by trophozoite and cyst counts. Both parasites occur all along the small intestine with G. muris, being mainly present in the anterior part and S. muris towards the posterior. The ear...
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PMID: 6214757
PDF is available here.
PDF is available here.
Abstract
We report that while orally-administered TGF-beta1 seems to confer partial protection against murine chronic babesiosis and acute trypanosomosis, no beneficial clinical effects were observed against acute babesiosis, malaria or toxoplasmosis. Taken together, these preliminary data suggest that the s...
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PMID: 19827745
PDF is available here.
PDF is available here.
Abstract
A total of ten intestinal parasite species (five protozoan and five helminth parasite species) were present in this community and polyparasitsm was common in individuals 5-24 years of age with no gendar related differences. Most of the infections were mild. The protozoan parasites of public health s...
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PMID: 20358789
PDF is available here.
PDF is available here.
Abstract
Avian Diseases (53)2 2009
Abstract
An outbreak of systemic histomoniasis in 9-to-11-wk-old meat-type male turkeys associated with high mortality is reported. Clinical signs in turkeys included anorexia, depression, diarrhea, loss of weight, and increased mortality between 7 and 13 wk of age. Seven-week cumulative mortality in the tur...
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PMID: 19630229
PDF is available here.
PDF is available here.
Abstract
Abstract
Microbiology (155)Pt 5 2009
Abstract
myo-Inositol (inositol) is an essential nutrient that is used for building phosphatidylinositol and its derivatives in eukaryotes and even in some eubacteria such as the mycobacteria. As a consequence, fungal, protozoan and mycobacterial pathogens must be able to acquire inositol in order to prolife...
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PMID: 19383710
PDF is available here.
PDF is available here.
Cellular Microbiology (11)4 2009
Abstract
We discuss recent work that has applied 2P microscopy to study models of infection and highlight the tremendous potential that this approach has for investigating host-pathogen interactions....
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PMID: 19170686
PDF is available here.
PDF is available here.
Parasitology (94 ( Pt 2))02 2009
Abstract
An enzyme-linked immunosorbent assay (ELISA) was used to detect antibodies to Encephalitozoon cuniculi in man, using spores derived from tissue culture as antigen. Negligible cross-reactions were found with other microsporidia of vertebrate or of invertebrate origin and there was no cross-reaction w...
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PMID: 3108830
PDF is available here.
PDF is available here.
Abstract
A case-crossover study compared rainfall in the 4 weeks before drinking water related outbreaks with that in the five previous control years. This included public and private drinking water related outbreaks in England and Wales from 1910 to 1999. Of 111 outbreaks, 89 met inclusion criteria and the...
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PMID: 18957770
PDF is available here.
PDF is available here.
Current Drug Targets (10)3 2009
Abstract
Current Drug Targets (10)3 2009
Abstract
We comment about three protein targets, identified in parasite genomes, and discuss the main features that may guide future efforts for virtual screening initiatives....
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PMID: 19275556
PDF is available here.
PDF is available here.
Current Drug Targets (10)3 2009
Abstract
We present data obtained by electron microscopy approaches of different parasitic protozoa, such as Trypanosoma cruzi, Leishmania spp., Giardia lamblia and trichomonads, under the action of drugs, demonstrating that the cell architecture organization is only determined in detail at the ultrastructur...
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PMID: 19275561
PDF is available here.
PDF is available here.
Current Drug Targets (10)3 2009
Abstract
We review the current status of these research efforts to develop genomic databases for protozoan parasites, such as the apicomplexan parasites, Trypanosoma cruzi and Leishmania spp. These databases may help in the discovery and development of new drugs against parasite-mediated diseases....
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PMID: 19275560
PDF is available here.
PDF is available here.
Parasitology (90 ( Pt 1))01 2009
Abstract
Novel hydroxynaphthoquinones are reported with outstanding efficacy against Plasmodium, Eimeria and Theileria species. Biochemical evidence is presented for the selective toxicity of these compounds being due to inhibition of parasite respiratory systems.
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PMID: 3920634
PDF is available here.
PDF is available here.
Parasitology (92 ( Pt 1))01 2009
Abstract
Evidence for the presence of 11 intestinal parasites in pre-school children from 4 rural villages in Ghana was obtained from an examination of stool samples. Striking differences were detected between the prevalence of some of the 6 common infections in the 4 villages. The prevalence of Ascaris lumb...
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PMID: 3960592
PDF is available here.
PDF is available here.
Abstract
This study was carried out to determine the role of non-biting cyclorrhaphan flies as carriers of human intestinal parasites at Woreta, northwestern Ethiopia. In total, 6530 flies were collected from four breeding sites and then examined for human intestinal parasites, mainly using the formol-ether...
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PMID: 18817940
PDF is available here.
PDF is available here.
Abstract
The prevalence of multi-infections with helminthes, protozoans and Campylobacter spp. in Guatemalan children is a reflection of differences in the risk factors related to pathogen transmission.
Two hundred and eighty-nine fecal samples were collected from children of...
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PMID: 19759480
PDF is available here.
PDF is available here.
Abstract
We examine tick-borne diseases other than Lyme disease that are found in Europe; namely: anaplasmosis, relapsing fever, tularemia, tick-borne encephalitis, tick-borne babesiosis and tick-borne rickettsiosis. Each disease is broken down into a description, epidemiology, signs and symptoms, diagnosis...
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PMID: 19367099
PDF is available here.
PDF is available here.
Abstract
In order to investigate a possible link between parasites and chronic urticaria, the prevalence of intestinal protozoans in stool samples of individuals with chronic urticaria (n=55) and healthy controls (n=43) were evaluated with native lugol, formol-ethyl acetate concentration and trichrom dye, mo...
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PMID: 19598090
PDF is available here.
PDF is available here.
Abstract
Macrolides and ketolides are two families of antibiotics that share the same mechanism of action. They bind to different bases of the peptidyl transferase center of 23S RNA. The antibacterial spectrum of these drugs virtually overlaps, but dissimilarities in the affinity and number of binding sites...
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PMID: 19625112
PDF is available here.
PDF is available here.
Abstract
Diarrheal diseases due to intestinal protozoa cause significant morbidity and mortality worldwide in a variety of patient populations. New literature on key pathogens Cryptosporidium, Cyclospora, Isospora, Giardia, and Entamoeba histolytica are discussed. SUMMARY: The recent medical literature on th...
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PMID: 19119509
PDF is available here.
PDF is available here.
Abstract
We recommend that individuals co-infected should receive prompt health care to control and prevent morbidity/mortality from anemia....
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PMID: 19743795
PDF is available here.
PDF is available here.
Abstract
This study reports on the occurrence of enteroparasites based on data from an ethnographic study of food handlers in the city of Cascavel, Paraná, Brazil. Fecal material from 343 food handlers of both sexes, between 14 and 75 years of age, was analyzed using Lutz, modified Ritchie and Ziehl-Neels...
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PMID: 19229388
PDF is available here.
PDF is available here.
Abstract
Occurrences of intestinal parasitosis in Indians of the Mapuera community (Oriximiná, State of Pará, Brazil) were evaluated. Within the context of group assessment, this study makes a contribution towards adequate knowledge of this subject, which is significant from a medical-sanitary point of...
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PMID: 19684989
PDF is available here.
PDF is available here.
Abstract
The paper analyzes the epidemiological situation associated with intestinal helminthic and protozoan diseases in the Kyrgyz Republic in the past 17 years (1991-2007). The analysis suggests that parasitic diseases are of wide spread in the republic. In the structure of infectious diseases, parasitic...
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PMID: 19566060
PDF is available here.
PDF is available here.
Abstract
Parasite infections in the central nervous system (CNS) are a major cause of morbidity and mortality worldwide, second only to HIV infection. Finding appropriate therapeutic measures to control CNS parasite infections requires an understanding of the tissue-specific host response. CNS parasitic dise...
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PMID: 19688329
PDF is available here.
PDF is available here.
Abstract
Drug development for other markets has shown that proteases are druggable targets, and protease inhibitors are now licensed or in clinical development to treat hypertension, diabetes, thrombosis, osteoporosis, infectious diseases, and cancer. Several protease targets have been validated by genetic o...
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PMID: 18978536
PDF is available here.
PDF is available here.
Abstract
Tick-borne pathogens in Thailand can cause diseases that result in productivity and economic losses in the livestock sector as well as cause debilitating illnesses in humans and their companion animals. With the advent of molecular techniques, accurate identification of tick-borne pathogens and prec...
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PMID: 19062690
PDF is available here.
PDF is available here.
Abstract
Gliding motility is an essential and fascinating apicomplexan-typical adaptation to an intracellular lifestyle. Apicomplexan parasites rely on gliding motility for their migration across biological barriers and for host cell invasion and egress. This unusual substratedependent mode of locomotion inv...
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PMID: 18814681
PDF is available here.
PDF is available here.
Tropical biomedicine (25)2 2008
Abstract
Appendicitis has a worldwide prevalence and affects all age groups. The aetiology of acute appendicitis is still much debated, many factors have been implicated. The pathology is likely to be due to obstruction of the lumen of the appendix. Parasites, both helminths and protozoa have been suggested...
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PMID: 18948889
PDF is available here.
PDF is available here.
Abstract
We describe a result reproducibility assessment tool, which can form part of a broader QA program, and which is based on the blinded resubmission of selected clinical samples, using concordance between the reports of the initial and resubmitted specimen as an indicator. Specimens preserved in sodium...
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PMID: 18448690
PDF is available here.
PDF is available here.
Abstract
Intestinal parasitic infections (IPI), especially helminths, represent a major public health problem that increase iron deficiency anaemia in developing countries. This study investigated the prevalence, risk factors and nutritional consequences of IPIs in 180 adolescent girls aged 12-17 years livin...
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PMID: 18395236
PDF is available here.
PDF is available here.
Investigacion clinica (49)2 2008
Abstract
An epidemiological and molecular study on E. histolytica and E. dispar was carried out in 428 patients with gastrointestinal symptomatology of diarrhea from different health centers in Cumana, Sucre state. The samples were processed through: direct examination with 0.85% physiological saline solutio...
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PMID: 18717268
PDF is available here.
PDF is available here.
Abstract
We focus on the advances in molecular epidemiology, diagnosis and current treatment of the most prevalent parasitic infections in HIV-infected patients. Most of these parasites are protozoa, whose diagnosis at the laboratory requires some adapted technique and expertise. We highlight the importance...
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PMID: 18588498
PDF is available here.
PDF is available here.
Parassitologia (50)1-2 2008
Abstract
In the 27 Member States of the European Union, zoonotic parasites transmitted by food are circulating with different prevalence according to the country, the environmental conditions, the human behaviour, and the socio-economic level. Foodborne parasites can be divided in two main groups according t...
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PMID: 18693552
PDF is available here.
PDF is available here.
Journal of Immunology (180)9 2008
Abstract
We review the biology of IL-10, its cellular sources, and its role in viral, bacterial, and protozoal infections....
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PMID: 18424693
PDF is available here.
PDF is available here.
Abstract
The gene encoding the membrane occupation and recognition nexus protein MORN1 is conserved across the Apicomplexa. In Toxoplasma gondii, MORN1 is associated with the spindle poles, the anterior and posterior rings of the inner membrane complex (IMC). The present study examines the localization of MO...
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PMID: 18310354
PDF is available here.
PDF is available here.
Trends in Parasitology (24)4 2008
Abstract
After more than three decades of research into the development of vaccines against parasites, a substantial number of antigens have been identified that, as purified native proteins or recombinant proteins, induce some protection against the target parasite. Very few achieve a degree of efficacy lik...
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PMID: 18342573
PDF is available here.
PDF is available here.
Abstract
The manipulation of glycosylation, mainly sialylation, holds enormous potential for understanding the biological functions of glycoproteins and glycolipids to treat many diseases. The existing knowledge in the field of glycobiology is exploited by glycotherapeutics for combating protozoan diseases....
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PMID: 18473927
PDF is available here.
PDF is available here.
Abstract
This paper studied gastrointestinal parasitosis in Nalout popularity. A hospital based study was done on a total of 800 stool samples from a private laboratory in Tigi city. The results showed an overall rate of 29.6%. Of these patients, 7.59% had double or triple parasitic infections. Children were...
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PMID: 19143135
PDF is available here.
PDF is available here.