Abstract
Reports of variable response to antiretroviral therapy as indicated by CD4 count has been of concern as facilities for viral load estimation/drug resistance testing is not available everywhere. Hence the present study. was done to assess the magnitude of problem in high prevalence state of Manipur a...
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PMID: 19886171
PDF is available here.
Abstract
Eosinophils have long been considered simply as effectors of adaptive immune responses during parasitic infections and inflammatory processes. Their role in allergic manifestations and mucosal responses is mediated by membrane receptors that allow them to interact with IgE and IgA antibodies. The re...
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PMID: 19718891
PDF is available here.
Abstract
In 2008, several publications have highlighted the role of climate change and globalization on the epidemiology of infectious diseases. Studies have shown the extension towards Europe of diseases such as Crimea-Congo fever (Kosovo, Turkey and Bulgaria), leismaniosis (Cyprus) and chikungunya virus in...
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PMID: 19216322
PDF is available here.
Abstract
We first describe the biology of DCs and their interactions with other cells types, paying particular attention to intestinal DCs. We, then, examine the ways in which this biology may become misdirected, resulting in inflammatory bowel disease. Finally, we discuss how DCs potentiate immune responses...
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PMID: 19121816
PDF is available here.
Abstract
During pregnancy, the mammalian endocrine system plays a leading role in maintaining the fetus, characterized by an increase in the level of hormones such as progesterone, oestradiol and some gonadotropic hormones. The immune system participates during pregnancy by self-regulating to prevent fetus r...
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PMID: 19212131
PDF is available here.
Abstract
Tropical diseases continue to cause significant health problems in developing nations. An overview of illnesses with notable cutaneous findings caused by protozoans and helminthes is provided. The role of the health care provider in disease management is described.
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PMID: 19873690
PDF is available here.
Abstract
RNA interference (RNAi) is a natural cellular process that regulates gene expression by a highly precise mechanism of sequence-directed gene silencing at the stage of translation by degrading specific messenger RNAs or blocking translation. In recent years, the use of RNAi for therapeutic applicatio...
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PMID: 19754220
PDF is available here.
Abstract
Between 2002-2009, 25 cases of non-parasytic splenic cysts were treated in the Center of General Surgery and Liver Transplantation of Fundeni Clinical Institute. Among these cases, 11 patients were approached classically (8 total splenectomie and 3 partial cystectomies) and 14 patients were operated...
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PMID: 19886050
PDF is available here.
Abstract
We found that evolutionary increases in mammalian sleep durations are strongly associated with an enhancement of immune defences as measured by the number of immune cells circulating in peripheral blood. This appeared to be a generalized relationship that could be independently detected in 4 of the...
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PMID: 19134175
PDF is available here.
Abstract
Parasites are accomplished evaders of host immunity. Their evasion strategies have shaped every facet of the immune system, driving diversity within gene families and immune gene polymorphisms within populations. New studies published recently in BMC Biology and Journal of Experimental Medicine docu...
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PMID: 19664200
PDF is available here.
Abstract
Autophagy is emerging as a central component of antimicrobial host defense against diverse viral, bacterial, and parasitic infections. In addition to pathogen degradation, autophagy has other functions during infection such as innate and adaptive immune activation. As an important host defense pathw...
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PMID: 18772897
PDF is available here.
Abstract
From January 1997 to December 2006, 568,499 person-year at risk (pyrs) and 10,037 deaths were recorded in the Manhiça DSS. 3,730 deaths with 246,658 pyrs were recorded for children under 15 years of age. Verbal autopsy interviews were conducted on 3,002 (80.4%) of these deaths. 73.6% of deaths we...
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PMID: 19236726
PDF is available here.
Abstract
We discussed how negative regulatory mechanisms of cytokine related intracellular signals attenuation are essential for ensuring and appropriate, controlled cellular immune response on parasitic infections....
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PMID: 20101583
PDF is available here.
Abstract
Though accurate prediction and high specificity and sensitivity can be achieved with several methods, the method based on hypergeometric distribution provides a significant advantage in term of positive predicting value with two to sixty folds the positive predicting values of other methods. CONCLUS...
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PMID: 19208186
PDF is available here.
Abstract
Since the advent of human immunodeficiency virus infection, with its profound and progressive effect on the cellular immune system, a group of human opportunistic pathogens has come into prominence. Opportunistic parasitic infection can cause severe morbidity and mortality. Because many of these inf...
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PMID: 19584497
PDF is available here.
Abstract
As an experimental system, Caenorhabditis elegans offers a unique opportunity to interrogate in vivo the genetic and molecular functions of human disease-related genes. For example, C. elegans has provided crucial insights into fundamental biologic processes, such as cell death and cell fate determi...
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PMID: 18852689
PDF is available here.
Abstract
Management of gastrointestinal infections according to usually mild, self-confining character is commonly based on symptoms. Specific therapy is apply in basis on clinical view and results of diagnostics
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PMID: 19899598
PDF is available here.
Abstract
Interleukin-1 is one of the most potent proinflammatory cytokines involved in many physiologically important processes both beneficial and pathological. It appears in two different forms: IL-1 alpha and IL-1 beta synthesized mainly by macrophages and monocytes. IL-1 alpha remains inside the cells an...
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PMID: 19670526
PDF is available here.