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Pathological Conditions, Signs and Symptoms (3)
Articles on Pathological Conditions, Signs and Symptoms
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A randomized investigation of methadone doses at or over 100mg/day, combined with contingency management
Drug Alcohol Depend 130(1-3):77-84 (2013) PMID 23195924 PMCID PMC3595382
Under double-blind conditions, dosages of methadone over 100mg/day, even when prescribed based on specific signs and symptoms, were not better than 100mg/day. This counterintuitive finding requires replication, but supports the need for additional controlled studies of high-dose methadone.... -
The treatment of acute gouty arthritis in complex hospitalized patients with anakinra.
Arthritis Rheum (2013) PMID 23650178
Twenty-six patients received 40 courses of anakinra therapy. In 67% of patients, pain improved significantly within 24 hours and complete resolution of signs and symptoms of gout occurred by day 5 in 72.5%. Seven patients receivedmultiple courses with no decrement in response with repeated treatment... -
Patients attended by palliative care teams: are they always comparable populations?
SpringerPlus 2(1):177 (2013) PMID 23646293
We have compared the basic epidemiological characteristics of patients attended by home palliative care teams (HPCT) in two autonomous regions of Spain. We carried out a coordinated analytical, observational and prospective study in two Spanish autonomous regions: Aragon and Catalonia. Data were kep... -
Diagnosis of Pompe Disease: Muscle Biopsy vs Blood-Based Assays.
JAMA Neurol (2013) PMID 23649721
The diagnosis of Pompe disease (acid maltase deficiency, glycogen storage disease type II) in children and adults can be challenging because of the heterogeneous clinical presentation and considerable overlap of signs and symptoms found in other neuromuscular diseases. This review ev... -
Dry Eye Syndrome, Posttraumatic Stress Disorder, and Depression in an Older Male Veteran Population.
Invest Ophthalmol Vis Sci (2013) PMID 23633658
DEQ5 scores were higher in the PTSD (mean=13.4; standard error[SE]=1.1; n=22) and depression (mean=12.0; SE=0.8; n=40) groups compared to the group without these conditions (mean=9.8; SE=0.4; n=186; p<0.01 and p=0.02, respectively). More patients in the PTSD and depression groups had severe dry eye... -
How Selective Are the New Guidelines for Treatment of Subclinical Hypothyroidism for Patients with Thyrotropin Levels At or Below 10 mIU/L?
Thyroid 23(5):562-5 (2013) PMID 23627903
According to the new ATA and AACE guidelines, L-T4 therapy would be considered for 92% of women with SCH and TSH ≤10 mIU/L.... -
Osteochondral lesions in children with juvenile idiopathic arthritis.
Pediatr Rheumatol Online J 11(1):18 (2013) PMID 23634779
Pain, and minor dysfunction of the joint are common complaints of children suffering from JIA. Earlier research has discounted the possibility of children who were not athletes presenting with this condition. However, this study demonstrates that these lesions also seem to be relatively common in pa... -
Successful early management of a female patient with a metabolic stroke due to ornithine transcarbamylase deficiency.
Pediatr Emerg Care 29(5):656-8 (2013) PMID 23640148
We report a 13-year-old girl who was diagnosed with OTC-D at the age of 3 years. On this occasion, the patient presented with vomiting, lethargy, and mental confusion. Despite biochemical parameters being within normal ranges, she was comatose within a few hours. She was promptly treated with a comb... -
Lupus enteritis: from clinical findings to therapeutic management.
Orphanet J Rare Dis 8(1):67 (2013) PMID 23642042
We report a series of 7 new patients with this rare condition who were referred to French tertiary care centers and perform a systematic literature review of SLE cases fulfilling the revised ACR criteria, with evidence for small bowel involvement, excluding those with infectious enteritis. We descri... -
Mining FDA drug labels for medical conditions.
BMC Med Inform Decis Mak 13(1):53 (2013) PMID 23617267
The results demonstrate that (1) medical conditions can be extracted from FDA drug labels with high performance; and (2) it is feasible to develop a framework for an intelligent database system....
