Abstract
Polidocanol sclerotherapy for hydrocele or spermatocele combines high efficiency with low morbidity, but the optimal dose is not known. We compared the efficacy and morbidity of 2 or 4 ml polidocanol sclerotherapy for hydrocele or spermatocele.
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PMID: 21849198
PDF is available here.
David W Kimberlin,
Richard J Whitley,
Wen Wan,
Dwight A Powell,
Gregory Storch,
Amina Ahmed,
April Palmer,
Pablo J Sánchez,
Richard F Jacobs,
John S Bradley,
Joan L Robinson,
Mark Shelton,
Penelope H Dennehy,
Charles Leach,
Mobeen Rathore,
Nazha Abughali,
Peter Wright,
Lisa M Frenkel,
Rebecca C Brady,
Russell Van Dyke,
Leonard B Weiner,
Judith Guzman-Cottrill,
Carol A McCarthy,
Jill Griffin,
Penelope Jester,
Misty Parker,
Fred D Lakeman,
Huichien Kuo,
Choo Hyung Lee,
Gretchen A Cloud and
National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group
Abstract
We enrolled neonates with HSV disease in two parallel, identical, double-blind, placebo-controlled studies. Neonates with central nervous system (CNS) involvement were enrolled in one study, and neonates with skin, eye, and mouth involvement only were enrolled in the other. After completing a regime...
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PMID: 21991950
PDF is available here.
Paul O'Connor,
Jerry S Wolinsky,
Christian Confavreux,
Giancarlo Comi,
Ludwig Kappos,
Tomas P Olsson,
Hadj Benzerdjeb,
Philippe Truffinet,
Lin Wang,
Aaron Miller,
Mark S Freedman and
TEMSO Trial Group
Abstract
We concluded a randomized trial involving 1088 patients with multiple sclerosis, 18 to 55 years of age, with a score of 0 to 5.5 on the Expanded Disability Status Scale and at least one relapse in the previous year or at least two relapses in the previous 2 years. Patients were randomly assigned (in...
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PMID: 21991951
PDF is available here.
Abstract
We report on a challenging case of percutaneous epicardial ablation of an epicardial accessory pathway located at right atrial appendage in a 28-year-old man with Wolff-Parkinson-White syndrome, who had a prior history of unsuccessful endocardial ablation. Percutaneous epicardial ablation may be a v...
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PMID: 21983769
PDF is available here.
Abstract
Multiple episodes of DILI in association with different drugs occur infrequently. In each individual, the type of injury was similar during the two DILI episodes, regardless of the causative drug. Second episodes of DILI are more likely to be associated with features of AIH. It remains uncertain if...
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PMID: 21338638
PDF is available here.
Abstract
We enrolled 3493 infants receiving antibiotics for suspected or proven serious infection and randomly assigned them to receive two infusions of either polyvalent IgG immune globulin (at a dose of 500 mg per kilogram of body weight) or matching placebo 48 hours apart. The primary outcome was death or...
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PMID: 21962214
PDF is available here.
Abstract
Group B streptococci are an important cause of neonatal infection, and cellulitis is rarely found to be the clinical manifestation. In the present case a premature boy developed cellulitis and antibiotic sensitive group B streptococci were detected in blood culture. Despite pertinent treatment for 14...
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PMID: 21936980
PDF is available here.
Abstract
This study aimed to assess the prevalence and natural course (incidence, persistence, remission, and relapse) of insomnia comorbid with cancer during an 18-month period.
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PMID: 21825267
PDF is available here.
Abstract
Human herpes simplex 1 virus (HSV-1) is a DNA virus that has the ability to lie latent and be subsequently re-activated at any point during a patient's life. In the immunocompetent patient, resolution of clinical signs and symptoms usually occurs spontaneously after 14 days. In the immunocompromised...
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PMID: 21905349
PDF is available here.
Abstract
The aim of the present study was to evaluate the smoking relapse rate among smokers who had become abstinent during admission for acute coronary syndromes. The association between smoking relapse and mortality was also analyzed. A cohort of 1,294 consecutive active smokers who had in...
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PMID: 21741609
PDF is available here.
Abstract
We used a simplified method for incising the external oblique aponeurosis, using a modified Collin Hartmann retractor, in 14 patients for the repair of large incisional hernias. Eight women and 6 men, with a mean (± standard deviation) age of 61.9 ± 14.9 years, underwent surgery. The median transv...
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PMID: 21871977
PDF is available here.
Abstract
Anti-phospholipid syndrome (APS) is an autoimmune prothrombotic disorder characterised by the predisposition to venous and/or arterial thrombosis and obstetric morbidity. Management of APS centres on attenuating the procoagulant state whilst balancing the risks of anticoagulant thera...
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PMID: 21558021
PDF is available here.
Abstract
We included all patients with systemic autoimmune diseases in whom the indication for treatment with TPE was a flare of the disease between 1999 and 2010. The indications for treatment, complications and outcomes were obtained from review of medical records.
A total of 31 patients (1...
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PMID: 21569864
PDF is available here.
Marcella Visentini,
Serena Ludovisi,
Antonio Petrarca,
Federica Pulvirenti,
Marco Zaramella,
Monica Monti,
Valentina Conti,
Jessica Ranieri,
Stefania Colantuono,
Elisa Fognani,
Alessia Piluso,
Carmine Tinelli,
Anna Linda Zignego,
Mario U Mondelli,
Massimo Fiorilli and
Milvia Casato
Abstract
We designed a phase II single-arm two-stage study (EUDRACT n. 2008-000086-38) to evaluate the efficacy of a lower dosage of rituximab, 250mg/m(2) given twice, for refractory mixed cryoglobulinemia. We present here the preliminary results in the first 27 patients enrolled. The overall response rate i...
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PMID: 21570494
PDF is available here.
Abstract
Refractory vasculitis occurs in 4-5% of patients with anti-neutrophil cytoplasmic antibody associated vasculitis (AAV). Differences between therapies used for refractory disease are mostly reflected in the percentages of complete and partial remissions, but also in the number of seri...
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PMID: 21600312
PDF is available here.
Abstract
We have experience exciting developments regarding the approval of new treatment options but few patients are reaching sustained remission and refractory patients continue to be a problem. Thus, it is critical to understand how clinicians can decrease the risk of refractoriness by close monitoring d...
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PMID: 21570496
PDF is available here.
Abstract
Authors present a case of a 5-month-old infant, in whom following an uneventful perinatal adaptation, symptoms of recurrent respiratory infections, vomiting and growth failure developed. Based on chest X-ray, right-sided diaphragmatic hernia was suspected. However, barium swallow exa...
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PMID: 21893481
PDF is available here.
Abstract
Improved clinical symptoms and modified gene expression profile of lymphocytes reveals anti-inflammatory effect upon whole body polarized light irradiation. Orv. Hetil., 2011, 152, 1492-1499....
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PMID: 21893480
PDF is available here.
Abstract
We present a foreign body case due to iatrogenic causes which had recurrent urinary tract infections for 5-6 months and that did not respond to medical treatment....
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PMID: 22013737
PDF is available here.
Abstract
We present here a 20- year- old female with hereditary complete C4 deficiency. Renal biopsy demonstrated renal AA amyloidosis. This unique case further substantiates that deficiency of classical pathway components predisposes to the development of recurrent microbial infections and that the patients...
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PMID: 21912034
PDF is available here.
Abstract
Amyloidosis represents a heterogeneous group of disorders of protein metabolism and is characterized by deposition of fibrillar proteins in the intra- and extracellular spaces. Here, a case of generalized amyloidosis associated with neutropenia is presented. She had a medical history...
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PMID: 21912038
PDF is available here.
Abstract
We determined that if mCRC patients remain cancer-free for 28 months after curative surgery, their chance of long-term survival is significantly better....
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PMID: 21894352
PDF is available here.
Abstract
DISEASE OVERVIEW: Follicular lymphoma (FL) is generally an indolent B-cell lymphoproliferative disorder of transformed follicular center B cells. FL is characterized by diffuse lymphoadenopathy, bone marrow involvement, splenomegaly, and less commonly other extranodal sites of involv...
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PMID: 21850659
PDF is available here.
Anders A Carlsson,
Christer C Wingren,
Malin M Kristensson,
Carsten C Rose,
Mårten M Fernö,
Håkan H Olsson,
Helena H Jernström,
Sara S Ek,
Elin E Gustavsson,
Christian C Ingvar,
Mattias M Ohlsson,
Carsten C Peterson and
Carl A K CA Borrebaeck
Abstract
We screened 240 sera from 64 patients with primary breast cancer. This unique longitudinal sample material was collected from each patient between 0 and 36 mo after the primary operation. The velocity for each serum protein was determined by comparing the samples collected at the primary operation a...
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PMID: 21844363
PDF is available here.
Robert F RF Bonvini,
Aljoscha A Rastan,
Sebastian S Sixt,
Elias E Noory,
Thomas T Schwarz,
Ulrich U Frank,
Marco M Roffi,
Pierre André PA Dorsaz,
Uwe U Schwarzwälder,
Karlheinz K Bürgelin,
Roland R Macharzina and
Thomas T Zeller
Abstract
The purpose of this study was to evaluate the technical feasability, safety, and 1-year efficacy of the endovascular treatment of atherosclerotic common femoral artery (CFA) obstructions.
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PMID: 21835313
PDF is available here.
Abstract
To evaluate the efficacy, tolerability, optimal dosing, and monitoring of azathioprine in patients with neuromyelitis optica (NMO).
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PMID: 21813788
PDF is available here.
Abstract
Orthotopic-liver-transplantation (OLT) in patients with Human-Immunodeficiency-Virus infection (HIV) and end-stage-liver-disease (ESDL) is rarely reported. The purpose of this study is to describe our institutional experience on OLT for HIV positive patients.
This is...
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PMID: 21813377
PDF is available here.
Marcello M Disertori,
Federico F Lombardi,
Simona S Barlera,
Aldo Pietro AP Maggioni,
Chiara C Favero,
Maria Grazia MG Franzosi,
Donata D Lucci,
Lidia L Staszewsky,
Gianna G Fabbri,
Silvia S Quintarelli,
Leopoldo L Bianconi and
Roberto R Latini
Abstract
Atrial fibrillation (AF) is a common arrhythmia that frequently recurs after restoration of sinus rhythm. In a consistent percentage of cases, AF recurrences are asymptomatic, thus making its clinical management difficult in relation to both therapeutic efficacy and thromboembolic risk.
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PMID: 21835301
PDF is available here.
Abstract
To evaluate the efficacy of supra-Tenon capsule placement of original Molteno vs Molteno 3 tube implants (Molteno Ophthalmic, Dunedin, New Zealand) in black patients with refractory glaucoma.
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PMID: 21825182
PDF is available here.
Abstract
We present two cases of the Kounis syndrome: (i) one was misdiagnosed as acute ST elevation myocardial infarction and treated with thrombolytics; (ii) the second diagnosis was made after a recurrence two months after the first incident....
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PMID: 21894822
PDF is available here.
Abstract
Cases of filamentary keratitis that are unresponsive to conventional medical treatment methods are often encountered in the clinical setting. Here we report on cases of filamentary keratitis that showed no recurrence for long periods after performing eyelid surgery.
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PMID: 21882586
PDF is available here.
Abstract
Relapse after hematopoietic stem cell transplantation (HSCT) is a stressful event for patients and families, but provides an opportunity for education and psychosocial support. Little available research satisfies the needs of transplantation recipients at this critical time in the ca...
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PMID: 21810574
PDF is available here.
Author(s) unavailable
Abstract
Study of spread and clinical-immunologic features of chronic and recurrent infectious diseases in patients with primary headache.
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PMID: 21809647
PDF is available here.
Abstract
The patient, a 58-year-old woman, underwent a partial excision of the right breast and an axillary lymph node dissection in October 2004. The histopathological findings were: solid tubular carcinoma with metastasis to 17 axillary lymph nodes; triple negative-type breast cancer. As ad...
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PMID: 21829078
PDF is available here.
Abstract
RTX could be an alternative in the therapy of patients with IS-dependent MCD, leading to successful cessation of other IS treatment....
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PMID: 21762648
PDF is available here.
Abstract
We were unable to show a convincing functional benefit from surgery for patients with an acute rupture of the tendo Achillis compared with conservative treatment in plaster....
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PMID: 21768631
PDF is available here.
Abstract
We reviewed the outcome of distal chevron metatarsal osteotomy without tendon transfer in 19 consecutive patients (19 feet) with a hallux varus deformity following surgery for hallux valgus. All patients underwent distal chevron metatarsal osteotomy with medial displacement and a medial closing wedg...
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PMID: 21768632
PDF is available here.
Abstract
We describe 22 cases of bizarre parosteal osteochondromatous proliferation, or Nora's lesion. These are surface-based osteocartilaginous lesions typically affecting the hands and feet. All patients were identified from the records of a regional bone tumour unit and were treated between 1985 and 2009...
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PMID: 21768639
PDF is available here.
Abstract
five of seven had a complete remission of the nephrotic syndrome and two of seven had a partial response. After a mean 24-month follow-up, only one patient experienced relapse of the nephropathy. Conclusions GN with monoclonal Ig deposits can be associated with MPGN or MN, which are correlated with...
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PMID: 21700823
PDF is available here.
Abstract
We found that recurrence rates of HSPN after transplantation are lower than previously reported. The actuarial risk of graft loss from recurrence in a first graft is 7.5% at 10 years....
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PMID: 21734091
PDF is available here.
Abstract
Initial epicardial coronary flow, as assessed by the Thrombolysis in Myocardial Infarction flow grade (TFG), prior to primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) has been associated with short- and long-term mortality in randomized clinical...
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PMID: 21742106
PDF is available here.
Abstract
Ablation is more successful for patients with paroxysmal atrial fibrillation (AF1) than for those with persistent (AF2) or longstanding persistent AF (AF3). Many patients fail initial ablation and undergo repeat ablations. Little is known about repeat ablation procedure times, complications, and outc...
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PMID: 21742108
PDF is available here.
C M O'Connor,
R C Starling,
A F Hernandez,
P W Armstrong,
K Dickstein,
V Hasselblad,
G M Heizer,
M Komajda,
B M Massie,
J J V McMurray,
M S Nieminen,
C J Reist,
J L Rouleau,
K Swedberg,
K F Adams,
S D Anker,
D Atar,
A Battler,
R Botero,
N R Bohidar,
J Butler,
N Clausell,
R Corbalán,
M R Costanzo,
U Dahlstrom,
L I Deckelbaum,
R Diaz,
M E Dunlap,
J A Ezekowitz,
D Feldman,
G M Felker,
G C Fonarow,
D Gennevois,
S S Gottlieb,
J A Hill,
J E Hollander,
J G Howlett,
M P Hudson,
R D Kociol,
H Krum,
A Laucevicius,
W C Levy,
G F Méndez,
M Metra,
S Mittal,
B-H Oh,
N L Pereira,
P Ponikowski,
W H Wilson,
S Tanomsup,
J R Teerlink,
F Triposkiadis,
R W Troughton,
A A Voors,
D J Whellan,
F Zannad and
R M Califf
Abstract
We randomly assigned 7141 patients who were hospitalized with acute heart failure to receive either nesiritide or placebo for 24 to 168 hours in addition to standard care. Coprimary end points were the change in dyspnea at 6 and 24 hours, as measured on a 7-point Likert scale, and the composite end...
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PMID: 21732835
PDF is available here.