Abstract
Evidence supporting the use of bioprostheses for heart valve replacement in young adults is accumulating. However, reoperation data, which may help guide clinical decision making in young patients, remains poorly defined in the literature.
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PMID: 21911822
PDF is available here.
Abstract
This study assessed outcomes of individuals with advanced cancer who required admission to an intensive care unit (ICU) after referral for an early clinical trial because they did not respond to conventional therapy.
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PMID: 21844494
PDF is available here.
Abstract
Patients with head and neck cancer (HNC) are at high risk of death resulting from noncancer causes and second malignancies (ie, competing mortality). Variation in competing mortality risk complicates individual treatment choices and design and interpretation of clinical studies.
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PMID: 21844503
PDF is available here.
Abstract
The RenalGuard System, which creates high urine output and fluid balancing, may be beneficial in preventing contrast-induced acute kidney injury.
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PMID: 21844075
PDF is available here.
Abstract
To investigate the frequency, phenomenology, and associated risk factors of REM sleep behavior disorder (RBD) in Parkinson disease (PD).
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PMID: 21832215
PDF is available here.
H H Jacobi,
P P Bauer,
P P Giunti,
R R Labrum,
M G MG Sweeney,
P P Charles,
A A Dürr,
C C Marelli,
C C Globas,
C C Linnemann,
L L Schöls,
M M Rakowicz,
R R Rola,
E E Zdzienicka,
T T Schmitz-Hübsch,
R R Fancellu,
C C Mariotti,
C C Tomasello,
L L Baliko,
B B Melegh,
A A Filla,
C C Rinaldi,
B P BP van de Warrenburg,
C C P CC Verstappen,
S S Szymanski,
J J Berciano,
J J Infante,
D D Timmann,
S S Boesch,
S S Hering,
C C Depondt,
M M Pandolfo,
J-S JS Kang,
S S Ratzka,
J J Schulz,
S S Tezenas du Montcel and
T T Klockgether
Abstract
We initiated the EUROSCA natural history study, a multicentric longitudinal cohort study of 526 patients with SCA1, SCA2, SCA3, or SCA6. We report the results of the 1- and 2-year follow-up visits....
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PMID: 21832228
PDF is available here.
Abstract
Prospective studies on the role of psychosocial factors in heart failure development are virtually nonexistent. The authors aimed to address the effect of psychosocial factors on the risk of heart failure hospitalization in men and women free of cardiovascular disease. In 1991-1993, the 8,670 partici...
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PMID: 21821541
PDF is available here.
Abstract
Nuclei of oculogyric nerves (principal oculomotor nucleus, trochlear nucleus and abducens nucleus) are densely vascularized brainstem structures. The aim of this study was to determine quantitative characteristics of the vascular network of these nuclei.
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PMID: 21905589
PDF is available here.
Abstract
The exacerbation of chronic obstructive pulmonary disease is most often induced by an infection of bacterial origin in over 50% of the cases (or mixed bacterial and viral infection). This study was aimed at evaluating clinical effects of antibiotics co-amoxiclav. Amoxiicillin with clavulanic acid in...
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PMID: 21905596
PDF is available here.
Abstract
In many developing countries and in countries in transition, an increased incidence of cerebrovascular disease has been observed. The aim of this study was to determine the influence of acute and chronic stress on the development of acute brain stroke and its relapse.
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PMID: 21905593
PDF is available here.
Abstract
Studies of Helicobater pylori infection rate among population of North-western federal district including St. Petersburg in 2007 - 2009.
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PMID: 21913398
PDF is available here.
Abstract
Frequency of occurrence detection of C4A and C4B complement system deficiency in patients with chronic gastrointestinal tract (GIT) diseases including gastric ulcer (GU) and duodenal ulcer (DU).
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PMID: 21913394
PDF is available here.
Abstract
Participation in physical activity (PA) and healthy nutrition are important factors that affects muscle and bone strength and the resultant functioning in the activities of daily living (ADL) skills including the overall quality of life (QoL) of geriatric individuals. However, the relationships betwe...
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PMID: 21913535
PDF is available here.
R G RG Miller,
D H DH Moore,
D A DA Forshew,
J S JS Katz,
R J RJ Barohn,
M M Valan,
M B MB Bromberg,
K L KL Goslin,
M C MC Graves,
L F LF McCluskey,
A L AL McVey,
T T Mozaffar,
J M JM Florence,
A A Pestronk,
M M Ross,
E P EP Simpson,
S H SH Appel and
Abstract
To use a historical placebo control design to determine whether lithium carbonate slows progression of amyotrophic lateral sclerosis (ALS).
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PMID: 21813790
PDF is available here.
N Nohata,
T Hanazawa,
N Kikkawa,
D Sakurai,
L Fujimura,
T Chiyomaru,
K Kawakami,
H Yoshino,
H Enokida,
M Nakagawa,
A Katayama,
Y Harabuchi,
Y Okamoto and
N Seki
Abstract
We found that miR-874 was significantly reduced in cancer cells. We focused on the functional significance of miR-874 in cancer cells and identification of miR-874-regulated novel cancer networks in MSSCC.
We used PCR-based methods to investigate the downregulated miRNAs in clinical...
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PMID: 21847129
PDF is available here.
Abstract
An 87-year-old man was found loss of consciousness after falling. He was found in a state of shock. Computed tomography showed rupture of aneurysm of the ascending aorta and aortic arch with acute aortic dissection. Echocardiography revealed aortic valve regurgitation and cardiac tam...
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PMID: 21899133
PDF is available here.
Karsten Suhre,
So-Youn Shin,
Ann-Kristin Petersen,
Robert P Mohney,
David Meredith,
Brigitte Wägele,
Elisabeth Altmaier,
CARDIoGRAM,
Panos Deloukas,
Jeanette Erdmann,
Elin Grundberg,
Christopher J Hammond,
Martin Hrabé de Angelis,
Gabi Kastenmüller,
Anna Köttgen,
Florian Kronenberg,
Massimo Mangino,
Christa Meisinger,
Thomas Meitinger,
Hans-Werner Mewes,
Michael V Milburn,
Cornelia Prehn,
Johannes Raffler,
Janina S Ried,
Werner Römisch-Margl,
Nilesh J Samani,
Kerrin S Small,
H-Erich Wichmann,
Guangju Zhai,
Thomas Illig,
Tim D Spector,
Jerzy Adamski,
Nicole Soranzo,
Christian Gieger,
Themistocles L Assimes,
Panos Deloukas,
Jeanette Erdmann,
Hilma Holm,
Sekar Kathiresan,
Inke R König,
Ruth McPherson,
Muredach P Reilly,
Robert Roberts,
Nilesh J Samani,
Heribert Schunkert and
Alexandre F R Stewart
Abstract
We report a comprehensive analysis of genotype-dependent metabolic phenotypes using a GWAS with non-targeted metabolomics. We identified 37 genetic loci associated with blood metabolite concentrations, of which 25 show effect sizes that are unusually high for GWAS and account for 10-60% differences...
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PMID: 21886157
PDF is available here.
Simon S Le Hello,
Rene S RS Hendriksen,
Benoît B Doublet,
Ian I Fisher,
Eva Møller EM Nielsen,
Jean M JM Whichard,
Brahim B Bouchrif,
Kayode K Fashae,
Sophie A SA Granier,
Nathalie N Jourdan-Da Silva,
Axel A Cloeckaert,
E John EJ Threlfall,
Frederick J FJ Angulo,
Frank M FM Aarestrup,
John J Wain and
François-Xavier FX Weill
Abstract
(See the editorial commentary by Hedberg, on pages 665-6.) National Salmonella surveillance systems from France, England and Wales, Denmark, and the United States identified the recent emergence of multidrug-resistant isolates of Salmonella enterica serotype Kentucky displaying high-level resistance...
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PMID: 21813512
PDF is available here.
Abstract
With all time-stable influences controlled, pain is positively related to symptoms of depression, although this relationship is substantially reduced in comparison with a model in which all time-stable confounds are not held constant. Mastery does not mediate this relationship because pain is not si...
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PMID: 21808069
PDF is available here.
Abstract
We enrolled all 132 patients undergoing hypercoagulability testing with positive LA results and in whom APC-R (with factor V-deficient plasma) was performed during a 2.5-year period. Among 121 patients without factor V Leiden, 24.0% had acquired APC-R; retrospective and prospective (mean follow-up,...
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PMID: 21846908
PDF is available here.