Merit Cudkowicz,
Michael E Bozik,
Evan W Ingersoll,
Robert Miller,
Hiroshi Mitsumoto,
Jeremy Shefner,
Dan H Moore,
David Schoenfeld,
James L Mather,
Donald Archibald,
Mary Sullivan,
Craig Amburgey,
Juliet Moritz and
Valentin K Gribkoff
Abstract
We tested the putative mitochondrial modulator dexpramipexole (KNS-760704; (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine) in subjects with ALS in a two-part, double-blind safety and tolerability study, with a preliminary assessment of its effects on functional decline and mortality. In...
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PMID: 22101764
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