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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Tablets (1):
Recent article
Tablets
Abstract
This study was aimed at improving the mucoadhesive properties of carboxymethyl dextran by the covalent attachment of cysteine. Mediated by a carbodiimide, l-cysteine was covalently attached to the polymer. The resulting CMD-cysteine conjugate (CMD-(273) conjugate) displayed 273+/-20 micromol thiol g...
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PMID: 20117156
PDF is available here.
PDF is available here.
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Analytica Chimica Acta (668)1 2010
Abstract
This work presents novel approach in low-pressure chromatography flow systems--two-column Sequential Injection Chromatography (2-C SIC) and its comparison with gradient elution chromatography on the same instrument. The system was equipped with two different chromatographic columns (connected to sel...
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PMID: 20457303
PDF is available here.
PDF is available here.
Abstract
Oralair Birch is a dissolving tablet being developed for sublingual immunotherapy (SLIT) of allergic rhinitis caused by birch pollen allergy. Oralair Birch is being developed by Stallergenes SA and Canadian licensee Paladin Labs Inc. Oralair Birch is a recombinant protein that is synthesized from th...
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PMID: 20419605
PDF is available here.
PDF is available here.
Clinical Nephrology (73)5 2010
Abstract
Co-administration of lanthanum with meal resulted in a smaller increase in serum P, compared with meal alone (p < 0.05). The smaller increase in serum P was similar for both chewed and crushed lanthanum. The amount of P excreted and FePi were also lower when chewed or crushed lanthanum was administe...
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PMID: 20420797
PDF is available here.
PDF is available here.
Abstract
We obtained the following pharmacokinetic parameters: AUC(0-inf) 63,418.31 +/- 22,141.69 and 67,094.70 +/- 22,487.2 ngh/ml; AUC0-24: 30,421.02 +/- 9,964.0 and 30,489.35 +/- 9,407.17, ng x h/ml; tmax: 2.77 +/- 1.76 and 1.95 +/- 1.89 h; C(max): 2,143.33 +/- 724.26 and 2,262.51 +/- 751.12 ng/ml, for A...
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PMID: 20420791
PDF is available here.
PDF is available here.
Abstract
This single-dose study found that both 250-mg immediate-release tablets of lysine clonixinate met the Mexican regulatory criteria for bioequivalence in these volunteers....
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PMID: 20420792
PDF is available here.
PDF is available here.
Abstract
We reviewed Grazax, a sublingual tablet containing standardised allergen extract of grass pollen.1 At the time, this product was licensed for the treatment of adults with proven grass-pollen-induced rhinitis and conjunctivitis (hay fever). However, we were not convinced that the effect on rhinoconju...
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PMID: 20447981
PDF is available here.
PDF is available here.
Abstract
A rapid reverse-phase HPLC method with evaporative light scattering detection (ELSD) was developed for the determination of forskolin in weight loss multi-herbals products. The analysis was performed by water-acetonitrile gradient elution at a temperature of 40 degrees C and a flow rate of 1.0 mL/mi...
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PMID: 20503921
PDF is available here.
PDF is available here.
Abstract
An unknown impurity (degradation product) present at a level below 0.1% in the initial sample was increased to 0.25% in 50 degrees C 3 M stability samples of lamivudine, zidovudine and nevirapine tablets for oral suspension, as detected by gradient reverse phase HPLC. This degradation product was is...
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PMID: 20503923
PDF is available here.
PDF is available here.
Abstract
Polyethylene glycols (PEGs) are well known as excipients in tablet dosage formulations. PEGs are generally known to be inert and have very few interactions with other components in the solid dosage forms. However, the physical nature of PEGs and how they affect the disintegration of tablets is not v...
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PMID: 20503926
PDF is available here.
PDF is available here.
YAKUGAKU ZASSHI (130)5 2010
Abstract
A well known superdisintegrant like croscarmellose sodium or crospovidone loses their quick disintegration property when compressed at more than 4 kg tablet crushing strength (TCS). Therefore, the objective of the present work was to develop a disintegrating system that could be used for preparing f...
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PMID: 20460872
PDF is available here.
PDF is available here.
Abstract
In this study, oral sustained release mucoadhesive nystatin tablets were developed to increase nystatin contact time with the oral cavity and mask its unpleasant taste.
The best formulation studied included sustained release agents and it was submitted to physical-mechanical characterization, taste...
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PMID: 19954405
PDF is available here.
PDF is available here.
Journal of Urology (183)5 2010
Abstract
All phytotherapeutic agents for benign prostatic hyperplasia in this study tested negative for alpha-blockers and 5alpha-reductase inhibitors. Inconsistent results in trials using phytotherapeutic agents are probably not explained by the presence of standard pharmaceuticals.
2010 American Urological...
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PMID: 20303529
PDF is available here.
PDF is available here.
Abstract
DPSGC 25 mg and 50 mg were more rapidly and consistently absorbed than diclofenac potassium 50-mg comparator tablets. The C(max) of DPSGC 25 mg was equivalent to the 50-mg diclofenac potassium comparator tablet. These characteristics may be beneficial when fast, consistent drug absorption is needed....
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PMID: 20187842
PDF is available here.
PDF is available here.
Abstract
Aprela, in development by Pfizer Inc, is a once-daily, orally administered, tissue-selective estrogen complex that contains the selective estrogen receptor modulator bazedoxifene (BZA) and conjugated equine estrogens (CE). Aprela was designed as an alternative to combination estrogen and progestin t...
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PMID: 20336595
PDF is available here.
PDF is available here.
Abstract
We performed serum pharmacokinetic studies in patients with multiple sclerosis after a single oral dose of 1200 mg lipoic acid. Patients received one of the three different racemic formulations randomly: tablet (Formulation A) and capsules (Formulations B and C). Mice pharmacokinetic studies were pe...
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PMID: 20150394
PDF is available here.
PDF is available here.
Psychopharmacology (209)3 2010
Abstract
Abstract
Compared with that in the control group, systolic blood pressure, diastolic blood pressure, mean arterial pressure of SHR decreased significantly in all the three administration groups (P < 0.01). Heart rates of nifedipine group was faster than other groups (P < 0.05). In combination group, contents...
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PMID: 20575395
PDF is available here.
PDF is available here.
Abstract
The demand for mouth dissolving tablets has been growing during the last decade especially for elderly and children who have swallowing difficulties. Etoricoxib is a new non-steroidal anti-inflammatory drug (NSAID) with selective cox-2 inhibitory activity, selective inhibition of cox-2 provides anti...
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PMID: 20363696
PDF is available here.
PDF is available here.
Abstract
Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulatio...
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PMID: 20363705
PDF is available here.
PDF is available here.
Abstract
The in-vitro characteristics of these formulations demonstrated a controlled release profile in both media but with different characteristics, as in Formulation 3 where faster dissolution profile obtained in water but slower one in pH 6.8 buffer. In-vivo the pharmacokinetic profile of these formulat...
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PMID: 20353746
PDF is available here.
PDF is available here.
Abstract
A simple, sensitive and specific LC-ESI/MS method was developed for the determination of pimozide in human plasma. Pimozide and cinnarizine (internal standard) were isolated from plasma samples by liquid-liquid extraction. The chromatographic separation was accomplished on a Thermo Hypersil-HyPURITY...
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PMID: 19969437
PDF is available here.
PDF is available here.
Anodic voltammetry of zolmitriptan at boron-doped diamond electrode and its analytical applications.
Abstract
The electrooxidative behavior and determination of zolmitriptan at a boron-doped diamond electrode were investigated using cyclic, linear sweep, differential pulse and square wave voltammetric techniques. Zolmitriptan undergoes irreversible oxidation at a peak potential of about +0.9 V (vs Ag/AgCl/3...
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PMID: 20432618
PDF is available here.
PDF is available here.
Abstract
The aim of this paper is the modification of the release behaviour of hydrophilic HPMC-based matrices of different substitution degree (E4M, F4M, K4M) by the introduction of a new inert polymeric excipient hydroxypropylcellulose-methyl methacrylate (HCMMA) at different proportions (75:25, 50:50 and...
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PMID: 19969052
PDF is available here.
PDF is available here.
Abstract
Modified lactoses are widely used as filler-binders in direct compression of tablets. Until today, little about the compaction behaviour of anhydrous alpha-lactose is known. In this study, a new method to prepare anhydrous alpha-lactose from alpha-lactose monohydrate by desiccation with heated ethan...
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PMID: 20005927
PDF is available here.
PDF is available here.