Abstract
Patient education and warnings have emerged as prominent interventions for improving drug safety. As part of the provision of information and guidance on safe use of drugs, patients often receive multiple pieces of written information when they obtain a prescription medication, including a Food and D...
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PMID: 21427296
PDF is available here.
Abstract
These results do not provide strong support for an association between NSAIDs and LUTS. However, the associations between over-the-counter NSAID use and certain urologic symptoms, particularly among women with arthritis, and the potential mechanisms involved should be evaluated in future studies....
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PMID: 21357657
PDF is available here.
Abstract
Lower bowel symptoms are common. A significant number of patients seek to treat their symptoms by purchasing over the counter medication.
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PMID: 21575332
PDF is available here.
Abstract
The Bradford Hill criteria represent an important tool for scientifically determining cause between environmental exposure and disease. Increased Food and Drug Administration oversight of homeopathic medications is needed to monitor the safety of these popular remedies....
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PMID: 20644061
PDF is available here.
Abstract
Most tested products had very low metal/metalloid levels (below the limit of quantification of the method), but the metal/metalloid levels in the remaining products were in the following ranges (in microg g(-1)): Pb 0.33-1.29 (6 samples), Cd 2.78 (1 sample), As 0.22 (1 sample), Hg 0.02-0.12 (24 samp...
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PMID: 20674842
PDF is available here.
Abstract
This pattern of admissions is new to the detoxification unit, and may relate to higher codeine content in the combination product, and marketing strategies. These cases likely represent the severer end of the spectrum of codeine dependency acquired from OTC pharmacy sources. The paucity of evidence...
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PMID: 20657632
PDF is available here.
Abstract
Prospective data collection is feasible in DARTNet and can enable comparative effectiveness and safety research....
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PMID: 20473193
PDF is available here.
Abstract
Both acute and overuse musculoskeletal injuries are common in adolescent athletes. Pharmacologic agents including nonsteroidal anti-inflammatory drugs, acetaminophen, and topical over-the-counter agents have been shown to be effective in controlling pain, but data regarding their efficacy in expedit...
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PMID: 20538155
PDF is available here.
Abstract
We report an unusual and emerging cause of profound hypokalaemia associated with a severe myopathy, attributable to misuse of Nurofen Plus, a readily available over-the-counter medication containing ibuprofen and codeine, and excessive ingestion of the caffeine-containing energy drink, Red Bull. The...
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PMID: 20513219
PDF is available here.
Abstract
The concordance between physician and patient report was assessed on 2702 patient-physician pairs. Agreement was excellent overall (kappa = 0.83, 95% confidence interval (CI): 0.81-0.85). Prevalences of exposure were very close between PS and PP for all classes of prescription CVDs. CONCLUSION: Usin...
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PMID: 20535758
PDF is available here.
Abstract
We focus on regulatory restrictions on Community Pharmacies and whether these have an impact on efficiency, access and equity and thus in the delivery of services community pharmacists provide to patients. Primary data collection through semi-structured interviews and secondary data collection throu...
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PMID: 20056292
PDF is available here.
Abstract
This study demonstrated that flexible dip tubes can improve the performance of many nasal sprays, and that shaking may have negative effects on spray weight uniformity....
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PMID: 19778208
PDF is available here.
Abstract
IMPORTANCE OF THE FIELD: Recurrent herpes labialis (RHL) is a significant disorder with social and health consequences that affects upwards of 20 - 40% of the adult population. Docosanol is the only FDA-approved topical agent that is available over the counter for management of RHL. Its mechanism of...
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PMID: 20210688
PDF is available here.
Abstract
Most Brazilian OTC products did not show a satisfactory efficacy against head lice. Resistance may be present. Ivermectin and coconut oil are promising compounds for topical treatment. Laboratory-based tests should be used to assess resistance patterns and to identify formulations of the active ingr...
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PMID: 20465674
PDF is available here.
Abstract
We present a case of ischemic colitis in a 42-year-old active duty service member after using the performance-enhancing supplement, NO-Xplode. In this report, we review the pharmacology of this supplement and its proposed mechanism of injury....
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PMID: 20358712
PDF is available here.
Abstract
We test how cultural and public health knowledge of antibiotics is distributed among pharmacy staff, local Mexican clients, and U.S. medical tourists in the bordertown of Nogales using a cultural consensus tool. We find that shared cultural models across these groups include public health statements...
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PMID: 20420303
PDF is available here.
Abstract
Twenty-six pharmacists participated in interviews. Safety was the over-arching consideration for pharmacists when making decisions. The subordinate themes were product, patient and professional factors. In terms of the product subordinate theme, use or consideration of evidence was secondary in the...
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PMID: 20158288
PDF is available here.
Abstract
Our results suggest that acupuncture in addition to usual care is associated with marked clinical improvement in hot flashes and menopause-related symptoms in perimenopausal or postmenopausal women....
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PMID: 19907348
PDF is available here.
Abstract
This article provides guidance and web-based resources regarding two frequent practice issues associated with medications in the workplace: dispensing of over-the-counter (OTC) medications in the occupational health setting, and the proper disposal of expired or otherwise unwanted prescription and n...
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PMID: 20180501
PDF is available here.
Abstract
The results characterize pilots as workers who are often highly motivated to consider the use of OTC medications, but who lack the knowledge, available information, and information-seeking habits to make informed decisions about OTC drug usage under the more complicated constraints of a safety-criti...
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PMID: 20131651
PDF is available here.
Abstract
We recommend that pharmacists keep individual records detailing patient experience and use of OTC medicines....
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PMID: 20873425
PDF is available here.
Abstract
We filled the same two prescriptions (prednisolone and amoxicillin) at 20 pharmacies (national grocery store chain [n = 1], regional grocery store chains [n = 4], national pharmacy chains [n = 3], national superstore chains [n = 3], and independently owned [n = 9]) across three states (Colorado,Geor...
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PMID: 20605545
PDF is available here.
Lung (188 Suppl 1)s1 2010
Abstract
As the number of published articles in the field of cough increases year on year, it is sometimes helpful to pause and review what might have passed us by. This "Clinical Year in Review" provides an opportunity to reflect on a number of important studies reported in the area of both adult and pediat...
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PMID: 19697083
PDF is available here.
Lung (188 Suppl 1)s1 2010
Abstract
Cough is a unique symptom because, unlike sneeze and other symptoms, it can be under voluntary control and this complicates clinical trials on cough medicines. All over-the-counter cough medicines (OTC) are very effective treatments because of their placebo effect. The placebo effect is enhanced by...
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PMID: 19760296
PDF is available here.
Abstract
We describe a 46-year-old African-American man who was receiving warfarin for a venous thromboembolism and experienced a decrease in his international normalized ratio (INR). No corresponding reduction had been made in his warfarin dosage, and no changes had been made in his concomitant drug therapy...
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PMID: 20030479
PDF is available here.
Abstract
This was a randomized, controlled, four-way crossover study in 45 subjects with a tendency to suffer from moderate heartburn following some meals. The study was designed to assess the time to onset of the perceived soothing and cooling effects of the alginate raft-forming products, Gaviscon Liquid (...
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PMID: 20515559
PDF is available here.
Abstract
Acetaminophen is an old and comfortable friend. In its over-the-counter forms (of which there are almost 100), it is used by millions of people for relief of pain and to treat mild fevers. When combined with an opioid as a prescription drug, it is often effective for more severe pain. Generally, for...
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PMID: 20142694
PDF is available here.
Alfonso Merante,
Pietro Gareri,
Norma Maria Marigliano,
Salvatore De Fazio,
Elvira Bonacci,
Carlo Torchia,
Gaetano Russo,
Pasquale Lacroce,
Roberto Lacava,
Alberto Castagna,
Giovambattista De Sarro and
Giovanni Ruotolo
Abstract
The present study describes a case of laxative-induced rhabdomyolysis in an elderly patient. An 87-year-old woman was hospitalized for the onset of confusion, tremors, an inability to walk, and a fever that she had been experiencing for 36 hours. She often took high dosages of lactulose and sorbitol...
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PMID: 20396636
PDF is available here.
Abstract
Consumers were generally not comfortable enough with their conventional health care providers to discuss their NHP-related ADRs. Consumers reported being more comfortable discussing NHP-related ADRs with personnel from health food stores, friends or family with whom they had developed trusted relati...
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PMID: 20184759
PDF is available here.
Abstract
Of the 682 (2.6%) subjects using nonprescription corticosteroids most were females: 471 (69%); married: 567 (83%); of low social class: 430 (63.1%); lived in the city center: 475 (69.6%). The majority (569, 83.5%) thought that corticosteroid use was safe and 463 (68.0%) did not feel guilty for using...
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PMID: 20357499
PDF is available here.
Abstract
The sample had a mean FTND score of 5.7 (SD = 2.2). About 41% smoked 11 to 20 cigarettes per day. Adolescent smokers who had used NRT were statistically but only marginally older than those who had not (15.9 vs 15.7 years; t-test= -2.60, P=0.01). FTND score, a measure of nicotine dependence, was hig...
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PMID: 20503900
PDF is available here.
Abstract
Female sexual arousal disorder (FSAD) occurs when a woman experiences distress due to the inability to attain or maintain adequate vaginal lubrication. Many treatments are still under investigation, and at this time, there are no FDA-approved medications available for the treatment of FSAD. Treatmen...
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PMID: 20949811
PDF is available here.
Abstract
Despite electronic systems designed to warn dispensing pharmacists of duplications of drug class and cumulative excessive doses, potentially toxic amounts of acetaminophen are commonly prescribed and dispensed to this population. Better systems, increased awareness, and education of patients, prescr...
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PMID: 20551297
PDF is available here.
Abstract
This analysis provides a method for educators to use when collecting curricula-refining evidence and specific findings for evaluating therapeutics curricula....
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PMID: 20221341
PDF is available here.
Abstract
OBJECTIVE: To improve student application of course content and learning in a self-care and nonprescription medications course. DESIGN: A precourse survey was administered to students to determine confidence in their ability to advise patients about nonprescription medications and to identify what t...
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PMID: 20221346
PDF is available here.
Author(s) unavailable
Abstract
When lifestyle measures and antacids are inadequate, and when no alarm symptoms are present, pantoprazole has a better risk-benefit balance than H2 receptor agonists.
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PMID: 20025090
PDF is available here.
Abstract
No statistically significant difference was found among the effects of these agents on MTT in group 1. In group 2, xylometasoline chloride, fluticasone propionate spray and sea water sprays prolonged the MTT. When the rhinomanometric scores at 150 daPa were assessed, use of xylometasoline chloride,...
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PMID: 19863321
PDF is available here.
Abstract
Orlistat's unique mechanism of action, beneficial effects on multiple co-morbidity surrogates and relatively mild adverse effect and drug interaction profile position it favorably as the first option for pharmacotherapy in comprehensive obesity management of adults and children....
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PMID: 19998527
PDF is available here.