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Plant Extracts (10):
Recent article
Plant Extracts
Abstract
We hypothesized that these may be putative targets for C. collinus action and we tested this by exposing rat renal brush border membrane (BBM) as well as cultured kidney cells to a boiled decoction of C. collinus. Exposure to the C. collinus decoction resulted in significant inhibition of vacuolar t...
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PMID: 21824057
PDF is available here.
PDF is available here.
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Abstract
Abstract
The cancer preventive activities of tea (Camellia sinensis, Theaceae) have been demonstrated in animal models for cancers at different organ sites and suggested by some epidemiological studies. Many mechanisms for cancer prevention have been proposed based on studies in cell lines, w...
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PMID: 21538856
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (153)19 2011
Abstract
Abstract
Abstract
We lack insight into the impact of structure and size for their capacity to affect immune responses.
This study addresses the importance of chemical structure, size, origin and presence of contaminants for the capacity of both dietary and non-food NSP to modulate DC. Of 28 NSP produc...
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PMID: 20938988
PDF is available here.
PDF is available here.
Abstract
A simple validated LC-UV method for the phytochemical analysis of four bioactive quassinoids, 13alpha(21)-epoxyeurycomanone (EP), eurycomanone (EN), 13alpha,21-dihydroeurycomanone (ED) and eurycomanol (EL) in rat plasma following oral (200 mg/kg) and intravenous administration (10 mg...
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PMID: 21485270
PDF is available here.
PDF is available here.
Abstract
Two new acyclic diterpenes, melidianolic acids A (1) and B (2), have been isolated from the bark of Aphanamixis grandifolia. Their structures were elucidated on the basis of spectroscopic and chemical methods. Melidianolic acids A (1) and B (2) showed antimalarial activity against Pl...
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PMID: 21485267
PDF is available here.
PDF is available here.
Abstract
The volatile components of both peel and juice of Japanese citrus, Kabosu (Citrus sphaerocarpa Hort. ex Tanaka) were investigated using SAFE (Solvent Assisted Flavor Evaporation) technique after solvent extraction. In this study, wine lactone, rose oxide, (2E)-4,5-epoxy-2-decenal, mi...
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PMID: 21485282
PDF is available here.
PDF is available here.
Abstract
We demonstrated here that the edible plant extract of Chrysanthemum coronarium L. (C. coronarium) remarkably activates Type-1 immunity in a Toll-like receptor (TLR)2-, TLR4-, and TLR9-dependent manner. In the present experiments, the extract of C. coronarium significantly induces interferon (IFN)-γ...
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PMID: 21144920
PDF is available here.
PDF is available here.
Abstract
Pectin-protein fraction SVC was isolated from the callus culture of the bladder campion (Silene vulgaris). The main components in it were residues of D-galacturonic acid, galactose, arabinose, rhamnose, and protein. Using ion-exchange chromatography, ultrafiltration, and acid and enzymatic hydrolysis...
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PMID: 21442925
PDF is available here.
PDF is available here.
British Journal of Nutrition (105)1 2011
Abstract
Biochemical components in alfalfa (Medicago sativa L.), such as saponins, can act as protecting factors against bio-stresses. Saponins are also antifeedants and show oral toxicity towards higher and lower animals. Changes in saponins, such as variation in the carbon skeleton, or hydrolysis of saponi...
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PMID: 20875185
PDF is available here.
PDF is available here.
British Journal of Nutrition (105)1 2011
Abstract
Ascorbic acid, and more recently, the carotenoids lutein and zeaxanthin have been shown to enhance Fe absorption. However, it is not clear whether Fe status improves when foods high in ascorbic acid and carotenoids are consumed with Fe-fortified meals. The present study aimed to investigate whether...
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PMID: 20727238
PDF is available here.
PDF is available here.
Abstract
The rising epidemic of obesity is associated with cognitive decline and is considered as one of the major risk factors for neurodegenerative diseases. Neuroinflammation is a critical component in the progression of several neurological and neurodegenerative diseases. Increased metabo...
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PMID: 21639917
PDF is available here.
PDF is available here.
Abstract
SIRT1 is a mammalian candidate molecule involved in longevity and diverse metabolic processes. The present study aimed to determine the effects of certain herbs and spices on SIRT1 expression. Human cell lines Daudi, Jurkat, U937 and K562 were cultured in RPMI-1640. Herb and spice po...
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PMID: 21573505
PDF is available here.
PDF is available here.
Abstract
We tested gene expression of PI3K, AKT1, JUN, CASP3 and DDIT3 in K562, BaF3P210(BCR-ABL) and BaF3 P210(BCR-ABLT315I) cell line treated for 6- and 12- hours with NPB001-05 and imatinib. The data indicates that NPB001-05 mediated cell death in K562 affects the function of ER stress. NPB001-05 shows an...
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PMID: 21622141
PDF is available here.
PDF is available here.
Abstract
We describe how to extract and quantify Rubisco activase content in leaf....
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PMID: 20960145
PDF is available here.
PDF is available here.
Abstract
We investigated the mechanism of the anti-allergy effect of FU. FU extract (80 mg/kg), orally administered to Sprague-Dawley (SD) rats, significantly inhibited the passive cutaneous anaphylaxis (PCA) reaction. It inhibited the compound 48/80-induced release of histamine from rat peritoneal mast cell...
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PMID: 21821956
PDF is available here.
PDF is available here.
Molecular Carcinogenesis (50)1 2011
Abstract
We find that berberine, when administered orally through the diet, inhibits in vivo tumorigenesis of both p53 expressing and p53 null lung tumor xenografts equally whether administered in its pure form or as a part of P. amurense extract. We also show that berberine induces G1 cell cycle arrest, inh...
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PMID: 21061266
PDF is available here.
PDF is available here.
Ugeskrift for laeger (172)50 2010
Abstract
Recent years have seen a rise in the demand for dermatological herbal and plant products as well as products containing chamomile. Extracts and decoctions made from this plant are often recommended by laymen for treatment of a number of skin diseases e.g. inflammation, wounds and itching. This syste...
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PMID: 21156115
PDF is available here.
PDF is available here.
Abstract
British Journal of Nutrition (104)12 2010
Abstract
High-fat or high-fat-high-sucrose diets are known to induce non-alcoholic fatty liver disease and this is emerging as one of the most common liver diseases worldwide. Some polyphenols have been reported to decrease rat hepatic lipid accumulation, in particular those extracted from red grapes such as...
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PMID: 20673376
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)12 2010
Chronic administration of Eucommia leaf stimulates metabolic function of rats across several organs.
Abstract
We used a metabolic syndrome-like rat model, produced by feeding a 35% high-fat diet (HFD), to examine potential anti-obesity and anti-metabolic syndrome effects and mechanisms of chronic administration of Eucommia leaf as an extract or green leaf powder. Eighty rats were studied for 3 months in ten...
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PMID: 20691136
PDF is available here.
PDF is available here.
Journal Of Diabetes (2)4 2010
Abstract
The present study investigated the effects of Nigella sativa aqueous extract and oil, as well as thymoquinone, on serum insulin and glucose concentrations in streptozotocin (STZ) diabetic rats.
Rats were divided into five experimental groups (control, untreated STZ-di...
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PMID: 20923501
PDF is available here.
PDF is available here.
Biocontrol Science (15)4 2010
Abstract
We conclude that KE possesses potent anti PRV activity, and the candidate responsible for the antiviral property was the polysaccharide fraction....
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PMID: 21212504
PDF is available here.
PDF is available here.
Biomedical Chromatography (24)12 2010
Abstract
A rapid HPLC method was developed and validated for the quantification of oxyresveratrol analog trans-2,4,3',5'-tetramethoxystilbene (oxyresveratrol tetramethyl ether, OTE) in rat plasma. Chromatographic separation was achieved on an RP-HPLC column, which was protected by a guard column through a 12...
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PMID: 21077256
PDF is available here.
PDF is available here.
Abstract
Abstract
We investigated the interaction between evodiamine and the aryl hydrocarbon receptor (AhR). Molecular modeling results revealed that evodiamine directly interacted with the AhR. Cytosolic receptor binding assay also provided the evidence that evodiamine could interact with the AhR with the K(i) valu...
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PMID: 20888792
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (152)44 2010
Abstract
Abstract
There are few true international meetings dedicated to covering multiple areas of toxicology. The XII International Congress of Toxicology (IUTOX) held from 19 to 23 July 2010 in Barcelona, Spain is one such meeting. The IUTOX is important as its emphasis is on chemical safety and integrating approa...
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PMID: 20843280
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)9 2010
Abstract
We evaluated the effects of a hexane-ethanol extract of Glycyrrhiza uralensis (HEGU), which lacks glycyrrhizin, on the metastatic characteristics of DU145 prostate cancer cells. HEGU inhibited basal and epidermal growth factor-induced cell migration, invasion and adhesion in a dose-dependent fashion...
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PMID: 20487583
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)9 2010
Abstract
These results suggest that Gen confers protection against Ovx-induced neurodegeneration by attenuating oxidative stress, lipid peroxidation and the mitochondria-mediated apoptotic pathway in a region- and dose-dependent manner....
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PMID: 20579403
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)9 2010
Abstract
We have investigated the in vitro and in vivo effects of watercress, which is a rich source of PEITC. We first demonstrated that, similar to PEITC, crude watercress extracts inhibited cancer cell growth and HIF activity in vitro. To examine the effects of dietary intake of watercress, we obtained pl...
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PMID: 20546646
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)9 2010
Abstract
We reported previously that genistein inhibited NAFLD by enhancing fatty acid catabolism. However, this molecular approach focused on hepatic metabolism. Thus, we have attempted to determine whether this anti-steatotic effect of genistein is linked to visceral adipocyte metabolism. C57BL/6J mice wer...
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PMID: 20687969
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)11 2010
[Biological treatment strategies of depression--psychopharmacology and non-pharmacological methods].
Abstract
Biological treatment procedures are based on evidence-based guidelines. According to all of them, a correct diagnosis of depression is required before starting therapy. Within recent years many different types of antidepressants have been introduced to the pharmacotherapeutic armamentarium. The "new...
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PMID: 21043020
PDF is available here.
PDF is available here.
Food & Function (1)2 2010
Abstract
We investigated the effects of tea catechins on the translocation of glucose transporter (GLUT) 4 in 3T3-L1 adipocytes. We found that the ethyl acetate fraction of green tea extract, containing abundant catechins, most decreased insulin-induced glucose uptake activity in 3T3-L1 cells. When the cells...
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PMID: 21776468
PDF is available here.
PDF is available here.
Safety and toxicological evaluation of Aflapin: a novel Boswellia-derived anti-inflammatory product.
Abstract
Boswellia serrata gum resin has been used for treatment of various ailments in different cultures for thousands of years. Aflapin(®) is a novel synergistic composition derived from B. serrata gum resin (Indian Patent Application No. 2229/CHE/2008). Aflapin is significantly better as...
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PMID: 20874664
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (152)43 2010
Abstract
Abstract
The metabolic syndrome is associated with increased risk for development of both cardiovascular disease and type 2 diabetes in humans. Because experimental data and clinical experience have shown that metabolic syndrome and caloric restriction have, at least partly, opposite pathophysiological pathw...
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PMID: 20823772
PDF is available here.
PDF is available here.
Abstract
Our results show that formulated probiotic-enriched diets can speed up the recovery of ulcerative dermatitis induced by A. hydrophila in carp....
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PMID: 21166313
PDF is available here.
PDF is available here.
Abstract
To investigate the effect of aqueous extract from Mangifera indica L. (MIE) on dextran sulfate sodium (DSS)-induced colitis in rats.
MIE (150 mg/kg) was administered in two different protocols: (1) rectally, over 7 d at the same time as DSS administration; and (2) once daily over 14 d (by oral gavag...
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PMID: 20954278
PDF is available here.
PDF is available here.
Medical Journal of Australia (193)8 2010
Abstract
We report a case of reversible complete heart block in a woman who had recently begun taking a herbal supplement containing black cohosh. We review the known side effect profile of black cohosh and its relationship to our case....
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PMID: 20955128
PDF is available here.
PDF is available here.
Cancer Biology & Therapy (10)8 2010
Abstract
We evaluate its molecular mechanism using a bioactivity-guided DLBS1425, an extract of Phaleria macrocarpa on MDA-MB-231 breast cancer cell line. DLBS1425 exhibited inhibition of proliferative, migratory and invasive potential of MDA-MB-231 in a dose-dependent manner, and significantly reduced phosp...
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PMID: 20703095
PDF is available here.
PDF is available here.
Abstract
The study aimed to evaluate the effect Echinacea extract (E) on the testicular antioxidants function in normal rats or that subjected to anti-androgenic compound, cyproterone acetate (CA). Rats were divided into 5 groups treated daily via an oral tube for two intervals 2 and 4 weeks,...
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PMID: 21319455
PDF is available here.
PDF is available here.
Abstract
A four-day static renewal acute toxicity test was performed to determine the LC(50) value of aqueous extract of Euphorbia tirucalli latex for the freshwater fish, Heteropneustes fossilis. The LC(50) values, their upper and lower confidence limits and slope functions were calculated. The LC(50) value...
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PMID: 20719388
PDF is available here.
PDF is available here.
Abstract
The present study was undertaken to investigate the effect of extracts of Schleichera oleosa (Sapindaceae) for its cytotoxic and hydroxyl radical-scavenging activities. The bark of the tree was used to prepare extracts with different solvents (i.e., hexane, chloroform, ethyl acetate, methanol, and w...
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PMID: 20545578
PDF is available here.
PDF is available here.
Mutation Research (702)1 2010
Abstract
The cytogenetic damage inflicted by the synthetic pyrethroid insecticide cypermethrin (CYP) on the bone-marrow of male white rats, as well as possible protective role of two natural elements: garlic extract (GRE, 500mg/kg) and vitamin C (VTC, 20mg/kg) against the mutagenic potential of the insectici...
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PMID: 20673810
PDF is available here.
PDF is available here.
Abstract
Two new phenolic compounds, 2,4,6-trihydroxy-5-methyl-acetophenone 2-O-beta-D-glucopyranoside (3), and benzyl alcohol 7-O-(3',4',6'-tri-O-galloyl)-beta-D-glucopyranoside (8), together with eight known phenolic compounds, were isolated from the 70% aqueous acetone extract of Eucalyptu...
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PMID: 21121264
PDF is available here.
PDF is available here.
Abstract
Cancer patients on chemotherapy treatment often seek herbal therapies and this may alter the clearance of anticancer drugs.
Many anticancer drugs are metabolized by CYPs and are substrates of P-glycoprotein, breast cancer resistance protein and multi-drug resistance proteins. CYPs and drug transport...
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PMID: 20701553
PDF is available here.
PDF is available here.
Abstract
Free radicals, in particular radical oxygen species (ROS), play an important role in the aetiology and pathogenesis of various diseases. Current research in many countries focuses on the use of local medicinal plants as a promising source of liver protective agents. This paper describes the hepatopr...
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PMID: 21121258
PDF is available here.
PDF is available here.
Abstract
Two new phenolic compounds, 2,4,6-trihydroxy-5-methyl-acetophenone 2-O-beta-D-glucopyranoside (3), and benzyl alcohol 7-O-(3',4',6'-tri-O-galloyl)-beta-D-glucopyranoside (8), together with eight known phenolic compounds, were isolated from the 70% aqueous acetone extract of Eucalyptus gomphocephala...
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PMID: 21121264
PDF is available here.
PDF is available here.
Abstract
We scored their content in extracts of ten populations of this species. Antibacterial and antifungal assays of the extracts and pure secoiridoid glycosides were performed against eight bacterial strains and five fungal species. Methanol extracts from both aerial parts and roots exhibited excellent a...
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PMID: 21121240
PDF is available here.
PDF is available here.
Abstract
Our results indicate, for the first time, that black currant skin containing an anthocyanin-rich fraction inhibits the proliferation of liver cancer cells, possibly due to additive as well as synergistic effects. This product could be useful in the prevention and treatment of human hepatocellular ca...
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PMID: 21121259
PDF is available here.
PDF is available here.
Abstract
Our results were of great interest underlying new industrial valorisation for ferns based on their broad spectrum of volatiles....
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PMID: 21121267
PDF is available here.
PDF is available here.
Annals of Pharmacotherapy (44)10 2010
Abstract
The herb Arnica montana, in topical formulations, has been reputed to decrease bruising and muscle pain. This claim has been inadequately and incompletely addressed.
To determine whether topical A. montana cream could decrease subjective leg pain following calf raises. Secondary outcomes were effect...
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PMID: 20807867
PDF is available here.
PDF is available here.
Abstract
I and II (5), agastachoside (6), apigenin-7-O-(3", 6"-di-(E) -p-coumaroyl) -beta-D-galactopyranoside (7), 5-hydroxy-3, 3', 4', 7- tetramethoxy flavone (8), 4', 5-dihydroxy-3, 3', 7-trimethoxyflavone (9), acacetin (10), crenatoside (11), isocrenatoside (12).
Compounds 1, 2, 4-7, 10 were isolated from...
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PMID: 21246823
PDF is available here.
PDF is available here.
Abstract
To compare the effects of Atractylodes lancea from different producing area on collagen-induced arthritis (CIA) in rats.
Wistar rats were induced by type II bovine collagen. CIA rats were treated daily with oral administration of A. lancea from the geo-authentic and non-authentic producing area of M...
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PMID: 21246829
PDF is available here.
PDF is available here.
Abstract
To study the chemical constituents in the roots of Indigofera pseudotinctoria.
The constituents were isolated by column chromatography and their structures were elucidated by spectroscopic methods.
Fourteen compounds were isolated from the ethanol extract of the plant and identified as maackiain (1)...
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PMID: 21246824
PDF is available here.
PDF is available here.
Abstract
Biebersteinia multifida is a common herb known in Iran. Its roots have been used locally in folk medicine of western region of Iran in the treatment of many diseases. The antioxidant activity and its inhibition of erythrocyte hemolysis were investigated.
1,1-diphenyl-2-picryl hydrazyl radical (DPPH)...
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PMID: 21222368
PDF is available here.
PDF is available here.
Pharmaceutical Biology (48)10 2010
Abstract
Extract of the calyx of Hibiscus sabdariffa Linn. (HS) (Malvaceae) has been reported to decrease fluid and food intake in lactating rats through a mechanism not yet fully understood. It has also been reported that rat pups undernourished during lactation have delayed puberty onset, suggesting a link...
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PMID: 20839905
PDF is available here.
PDF is available here.