Abstract
We aimed to systematically study the effect of prosthetic foot mechanics on gait, to gain insight into fundamental prosthetic design principles. We varied a single parameter in isolation, the energy-storing spring in a prototype prosthetic foot, the Controlled Energy Storage and Return (CESR) foot,...
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PMID: 21708509
PDF is available here.
Abstract
We find that the system can behave as a particle diode for both overdamped and underdamped cases. For low frequencies, the transport from the free end to the ac acting end is prohibited, while the transport from the ac acting end to the free end is permitted. However, the polarity of the particle di...
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PMID: 21728489
PDF is available here.
Abstract
An important part of any model of vehicle crashes is the development of a procedure to estimate crash injury severity. After reviewing existing models of crash severity, this paper outlines the development of a modelling approach aimed at measuring the injury severity of people in two-vehicle road cr...
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PMID: 21376862
PDF is available here.
Abstract
We discuss available data concerning the contribution of different potential mechanisms by which tubal ligation might prevent ovarian cancer. Included were studies published in English, identified through a literature search using PubMed and EMBASE. Four main mechanisms are discussed: (a) a screenin...
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PMID: 21355863
PDF is available here.
Abstract
This study evaluated the effect of heat treatment on CrNi stainless steel orthodontic archwires. Half of forty archwires of each thickness - 0.014" (0.35 mm), 0.016" (0.40 mm), 0.018" (0.45 mm) and 0.020" (0.50 mm) (totalling 160 archwires) - were subjected to heat treatment while th...
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PMID: 21359492
PDF is available here.
Abstract
We have developed procedures for mechanical disruption of leaf tissues in order to isolate metabolically active bundle sheath strand cells and thylakoids practically free from cross-contamination coming from mesophyll cells. The procedures are described in detail together with useful practical sugge...
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PMID: 20960140
PDF is available here.
Abstract
We examined gene flow and documented spatial variation in crushing resistance in the freshwater snails Mexipyrgus churinceanus, Mexithauma quadripaludium, Nymphophilus minckleyi, and its relationship to the relative frequency of the crushing morphotype in the trophically polymorphic fish Herichthys...
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PMID: 21799865
PDF is available here.
Yoshikazu Hara,
Shu Wakino,
Yoshiyuki Tanabe,
Maki Saito,
Hirobumi Tokuyama,
Naoki Washida,
Satoru Tatematsu,
Kyoko Yoshioka,
Koichiro Homma,
Kazuhiro Hasegawa,
Hitoshi Minakuchi,
Keiko Fujimura,
Koji Hosoya,
Koichi Hayashi,
Koichi Nakayama and
Hiroshi Itoh
Abstract
We identify adipocyte signaling through the guanosine triphosphatase Rho and its effector Rho-kinase as one such mechanism. Mice fed a high-fat diet (HFD) showed increased Rho-kinase activity in adipose tissue compared to mice fed a low-fat diet. Treatment with the Rho-kinase inhibitor fasudil atten...
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PMID: 21266714
PDF is available here.
Abstract
We have batch-fabricated cantilevers with ∼100 nm diameter nickel nanorod tips and force sensitivities of a few attonewtons at 4.2 K. The magnetic nanorods were engineered to overhang the leading edge of the cantilever, and consequently the cantilevers experience what we believe is the lowest surf...
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PMID: 21082863
PDF is available here.
Abstract
We have used brownian dynamics simulations to study the dynamics of a bead-and-spring polymer subject to a flashing ratchet potential. To elucidate the role of hydrodynamic (HD) interactions, simulations were carried out for the cases where HD interactions are present and when they are absent. The a...
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PMID: 21230524
PDF is available here.
Abstract
This work aimed to identify technological steps that can increase fat hydrolysis and volatile compounds production in hard cheeses; these biochemical events have been related with improved piquant taste and development of genuine flavor during cheese ripening. For that purpose, 2 different pretreatm...
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PMID: 20854988
PDF is available here.
Abstract
Ultrafine fibers were successfully fabricated from Channel catfish skin-extracted gelatin via electrospinning (ES). Important ES parameters, such as concentration of aqueous acid and fish gelatin solutions, and electric field intensity were examined to investigate the effects on the morphology of th...
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PMID: 20600270
PDF is available here.
Abstract
Screw fixation can be extremely difficult to achieve in osteoporotic (OP) bone because of its low strength. This study determined how pullout strength is affected by placing different bone screws at varying angles in normal and OP bone models. Pullout tests of screws placed axially, and at angles to...
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PMID: 20558097
PDF is available here.
Abstract
This work deals with the fabrication and characterization of nanostructured forsterite bulk. This material may have better biocompatibility and mechanical properties than coarse grain forsterite for the development of bone tissue engineering materials. Nanostructured forsterite bulks...
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PMID: 20696418
PDF is available here.
Abstract
Significant improvement of solubilization kinetics of poorly soluble vinpocetine was obtained through a mechanochemical activation process in presence of micronized crospovidone. Drug-to-polymer weight ratio and milling time variables resulted to have statistically significant impacts on the activati...
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PMID: 20839363
PDF is available here.
Abstract
We have developed here is conceptually satisfying for flexural, and provides an easily usable tool for rational biomaterials design.
Copyright 2010 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved....
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PMID: 20542551
PDF is available here.
Abstract
Our results show that the optical tweezers may serve as a unique tool for the measurement of DEP forces in various applications....
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PMID: 20634874
PDF is available here.
Abstract
We conducted face-to-face interviews with 14 leading climate scientists, using formal methods of expert elicitation. We structured the interviews around three scenarios of radiative forcing stabilizing at different levels. All experts ranked "cloud radiative feedbacks" as contributing most to their...
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PMID: 20616045
PDF is available here.
Abstract
Our results suggest that the agreement between the two event detection methods depended on gait speed, but the differences were small. The data determined using kinematic/ultrasound-based and GRF-based methods were comparable in healthy participants.
Copyright 2010 IPEM. Published by Elsevier Ltd....
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PMID: 20226713
PDF is available here.
Abstract
We describe the design of a device that overcomes these limitations by combining material properties, new design concepts, and microtechnology. 4-hydroxybutyl acrylate (4-HBA) was used as a backbone hydrogel material, and its actuating behavior, bending force, and elasticity were extensively charact...
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PMID: 20376390
PDF is available here.
Abstract
A direct fabrication method capable of producing fully-reversible, tunable nanochannel arrays, without the use of a molding step, is described. It is based on tunnel cracking of a readily-prepared brittle layer constrained between elastomeric substrates. The resulting nanochannels have adjustable cr...
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PMID: 20517560
PDF is available here.
Abstract
We describe a method to correct the errors induced by viscous drag on the cantilever in macromolecular manipulation experiments using the atomic force microscope. The cantilever experiences a viscous drag force in these experiments because of its motion relative to the surrounding liquid. This visco...
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PMID: 20590242
PDF is available here.
Abstract
We have studied the effect of ASCs on primary tendon repair in in-vivo model. In this paper, we sought to discuss tendon tissue engineering by focusing on culture of tenocytes, biomaterials, scaffolds, mechanical loading, fibroblasts and mesenchymal stem cells and mainly on adipose derived stem cell...
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PMID: 19941450
PDF is available here.
Abstract
We examine the hypothesis that polymer-solvent interfacial free energy is adequate to describe the energetics of the collapse of a hydrophobic homopolymer chain at fixed temperature, which serves as a much simplified model for studying the hydrophobic collapse of a protein. This implies that changes...
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PMID: 20405838
PDF is available here.
Abstract
We report the step by step self-assembly from nanostructure to microstructure (bottom-up approach through X-ray diffraction (1.6 nm), small angle neutron scattering (SANS) (11.6 nm), atomic force microscopy (70 nm smaller crystallite from enlarged image and 450 nm greater crystallites), and polarizi...
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PMID: 20361786
PDF is available here.
Abstract
The mean period of follow-up was 28 months (range 20 to 38 months). All the cases obtained bone union in average 3.3 months (from 3 to 4.5 months). There were no complications such as deep infection, deep vein thrombosis, pulmonary embolism and bone nonunion. The results of clinical evaluation accor...
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PMID: 20486383
PDF is available here.
Abstract
We then aim to produce position-dependant observables such as ion-current density, beam energy distribution, and emittance for each charge states to be compared to simulations of ECR e-heating, plasma simulation, beam formation, and transport....
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PMID: 20192349
PDF is available here.
Abstract
We show that the spin-vortex-mediated stimulus creates two dramatic effects: compromised integrity of the cellular membrane, and initiation of programmed cell death. A low-frequency field of a few tens of hertz applied for only ten minutes was sufficient to achieve approximately 90% cancer-cell dest...
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PMID: 19946279
PDF is available here.
Abstract
We have computed the hydrodynamic radius Rh and intrinsic viscosity [eta] of a large number of random coil polymer models by path integration. We examine the effects of chain length, solvent quality, monomer size and shape, and chain stiffness on the approach of these transport properties to the lim...
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PMID: 20365586
PDF is available here.
Abstract
There were statistically significant differences in the failure loads of elastomerics that had not be placed in the mouth and those that had been in the mouth for 6 weeks. There were no differences in the static frictional forces produced by conventional and Super Slick ligatures either before or af...
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PMID: 19852658
PDF is available here.
Abstract
We can further understand the physical mechanisms underlying microtubule-mediated centrosome positioning. Here, we summarize how we formulated the biophysical properties of microtubules in order to construct a numerical model of centrosome positioning in Caenorhabditis elegans embryos. Microtubules...
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PMID: 20719284
PDF is available here.
Abstract
We examined whether acidic buffer sensitizes thin muscular afferents to mechanical stimulus using single-fiber recording. The EDL muscle with the common peroneal nerve attached was excised from 17-male SD rats under pentobarbital anesthesia. After identifying single thin afferent fibers, mechanical...
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PMID: 20217373
PDF is available here.
Abstract
The goal of the study is to evaluate if the use of rotary nickel-titanium (RNT) instruments, as Hedstroem files, is safe. Twelve twisted files (TF) RNT instruments size 06-25 were selected and randomly divided in 2 groups of 6 instruments each. Group A (new instruments) were used as control. Group B...
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PMID: 21169671
PDF is available here.
Abstract
We describe methods for the isolation and culture of decidual NK cells, decidual stromal cells and trophoblast cells from human first trimester tissue samples....
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PMID: 20033659
PDF is available here.
Abstract
We aimed at the synthesis of hydrophobic, melt-processable AN-based copolymers with adjustable elastic properties for preparation of model scaffolds with controlled pore geometry and size. For this purpose a series of copolymers from acrylonitrile and n-butyl acrylate (nBA) was synthesized via free...
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PMID: 20675924
PDF is available here.
Abstract
A series of polyurethane (PU) co-polymers with designable molecular weight between cross-linking dots was synthesized by a hydrogen transfer polymerization route from polyaniline (PANI), poly(ethylene glycol) (PEG), various curing agents and chain extenders using dibutyltin dilaurate as a catalyst....
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PMID: 20507713
PDF is available here.
Abstract
I was increased, as evidenced by DNA assay and histological and immunofluorescence analysis. Thus, tendon regeneration, indicated by improved mechanical and biological properties, was demonstrated, confirming the effect of mechanical stimulation. It could be concluded that the dynamic tensile stimul...
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PMID: 20507714
PDF is available here.
Abstract
We fabricated porous three-dimensional PLGA scaffolds using residence times of 1, 3, 5 and 7 days for groups 1 through 4, respectively. Degradation behavior of the scaffolds was observed for 7 weeks in phosphate-buffered saline solution (pH 7.4) at 37 degrees C. The molecular weight, glass transitio...
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PMID: 20507709
PDF is available here.
Abstract
A series of interpenetrating polymer networks (IPNs) of vinyl-terminated polyurethane (VTPU) and poly(N-isopropylacrylamide) (PNIPAAm) was prepared by free radical polymerization. The effects of IPN composition and cross-linking density on the thermo-responsive and mechanical properties have been st...
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PMID: 20507708
PDF is available here.
Abstract
Bacterial cellulose (BC)-chitosan (BCC) films made via bio-co-polymerization by Acetobacter xylinum were developed and characterized for physical and biological properties. With the incorporation of chitosan MW 3 x 10(4) and 8 x 10(4) into bacterial cellulose, the modified films (BCC-MW 30,000 and B...
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PMID: 20507705
PDF is available here.
Abstract
Five polyurethane vascular grafts with three different chemistries were investigated in terms of device function, healing characteristics and material stability in a canine abdominal aorta model for prescheduled periods of 1 and 6 months. Corvita-reinforced grafts, with walls made of poly(carbonate...
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PMID: 20507718
PDF is available here.
Abstract
These results were explained in terms of the calcium chelating and adhesive properties of PVA vehicle system. The practical implication of the results is that this method provides a simple but efficient technique for coating the fiber surface of an initially non-bioactive material with low-crystalli...
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PMID: 20507712
PDF is available here.
Abstract
The purpose of this work is to develop poly(vinyl alcohol) (PVA) hydrogels incorporating large amounts of beta-cyclodextrin (beta-CD) in order to improve ocular drug loading and to sustain drug release. First, the mono-methacrylated-beta-CD monomer (MA-beta-CD) and the methacrylated-PVA macromer (PV...
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PMID: 20507706
PDF is available here.
Abstract
In vitro osteogenesis was successfully achieved with synovium-derived mesenchymal stem cells (SMSCs), which intrinsically have a strong chondrogenic tendency, by in situ release of alendronate (AL) and dexamethasone (Dex) from poly(lactic-co-glycolic acid) (PLGA)/hydroxyapatite (HA) sintered microsp...
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PMID: 20507717
PDF is available here.
Abstract
We used electromyography to measure the activity of the jaw-closing, jaw-opening, and lip-closing muscles while healthy adults ate one mouthful of buckwheat noodles. Slurping the noodles required a longer mastication period but smaller muscle activity per movement than chewing the same samples. Tota...
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PMID: 20057146
PDF is available here.
Abstract
The textural properties of cooked rice were investigated in the presence and the absence of gum arabic (GA) and soybean soluble polysaccharide (SSPS). SSPS was more effective in increasing the hardness and in decreasing the stickiness of the rice grains than GA. For both polysaccharides, the increas...
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PMID: 20057116
PDF is available here.
Abstract
We theorized that mechanically agitating the virus-containing cell suspensions would increase the movement of viruses and target cells, resulting in increase of contact between them. Application of our mechanical agitation for transduction process has increased the absorption of retrovirus particles...
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PMID: 19937144
PDF is available here.
Abstract
We theorized that mechanically agitating the virus-containing cell suspensions would increase the movement of viruses and target cells, resulting in increase of contact between them. Application of our mechanical agitation for transduction process has increased the absorption of retrovirus particles...
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PMID: 19937144
PDF is available here.
Abstract
We theorized that mechanically agitating the virus-containing cell suspensions would increase the movement of viruses and target cells, resulting in increase of contact between them. Application of our mechanical agitation for transduction process has increased the absorption of retrovirus particles...
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PMID: 19937144
PDF is available here.
Abstract
We theorized that mechanically agitating the virus-containing cell suspensions would increase the movement of viruses and target cells, resulting in increase of contact between them. Application of our mechanical agitation for transduction process has increased the absorption of retrovirus particles...
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PMID: 19937144
PDF is available here.
Abstract
We theorized that mechanically agitating the virus-containing cell suspensions would increase the movement of viruses and target cells, resulting in increase of contact between them. Application of our mechanical agitation for transduction process has increased the absorption of retrovirus particles...
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PMID: 19937144
PDF is available here.
Abstract
We theorized that mechanically agitating the virus-containing cell suspensions would increase the movement of viruses and target cells, resulting in increase of contact between them. Application of our mechanical agitation for transduction process has increased the absorption of retrovirus particles...
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PMID: 19937144
PDF is available here.
Abstract
Altering the shape and properties of a material through external factors such as heat, light, pressure, pH, electric or magnetic fields, or the introduction of a guest molecule, is an attractive prospect. In this Perspective, piezochromic luminescent materials - which change the colour of their lumin...
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PMID: 21378953
PDF is available here.
Abstract
We have generated scaffolds that are elastic to approximate soft tissue mechanical properties, are nanofibrous to mimic fibrous nature of extracellular matrix (ECM), have aligned structure to guide cellular alignment, and are capable of releasing insulin-like growth factor (IGF-1) to administrate ce...
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PMID: 19689108
PDF is available here.
Abstract
We analyzed the mechanical properties of transected sciatic nerves repaired with epineural application of ethyl-cyanoacrylate and the short term consequences of cyanoacrylate application on impulse conduction. Results showed that nerves coapted with ethyl-cyanoacrylate were capable of bearing in viv...
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PMID: 18570316
PDF is available here.
Abstract
Polyimides have been widely used for biosensor encapsulation and more recently as substrates for neural implants. They have excellent thermal stability, high chemical resistance, and can be prepared as thin, flexible films. Photosensitive polyimides present similar physical properties to polyimides,...
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PMID: 18563817
PDF is available here.
Abstract
The viscoelastic properties of confined polymer solutions are probed by particle-tracking microrheology. The mean squared displacement of spherical probe particles embedded in the solution and the storage and loss moduli of the system are measured as the level of confinement is increased. It is foun...
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PMID: 19594126
PDF is available here.
Abstract
We present and discuss the evolution in the use of MEMS and NEMS, which are basically cantilever-type sensors, as good analytical tools for a wide variety of applications. We discuss the analytical features and the practical potential of micro(nano)-cantilever sensors, which combine the synergetic a...
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PMID: 19562189
PDF is available here.