Dae-Hyeong DH Kim,
Nanshu N Lu,
Rui R Ma,
Yun-Soung YS Kim,
Rak-Hwan RH Kim,
Shuodao S Wang,
Jian J Wu,
Sang Min SM Won,
Hu H Tao,
Ahmad A Islam,
Ki Jun KJ Yu,
Tae-il TI Kim,
Raeed R Chowdhury,
Ming M Ying,
Lizhi L Xu,
Ming M Li,
Hyun-Joong HJ Chung,
Hohyun H Keum,
Martin M McCormick,
Ping P Liu,
Yong-Wei YW Zhang,
Fiorenzo G FG Omenetto,
Yonggang Y Huang,
Todd T Coleman and
John A JA Rogers
Abstract
We describe systems incorporating electrophysiological, temperature, and strain sensors, as well as transistors, light-emitting diodes, photodetectors, radio frequency inductors, capacitors, oscillators, and rectifying diodes. Solar cells and wireless coils provide options for power supply. We used...
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PMID: 21836009
PDF is available here.
Abstract
The main aim of present investigation was to develop sustained release matrix tablets of Gliclazide using fruit mucilage from the plant Ficus glomerata. Varying ratios of drug and polymer viz. 1:0.25, 1:0.5, 1:0.75, 1:1.0 and 1:1.25 were selected for the study. The flow properties of powdered mucilag...
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PMID: 21715275
PDF is available here.
Abstract
Two series of poly(ether-ester)-based bis-functional macromers terminated with acrylate groups and a well-defined number of ester bonds were synthesized. One series had a chain of 1, 3 or 5 ester bonds at both ends of the central poly(ethylene glycol) block (molecular weight, about 1...
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PMID: 21095246
PDF is available here.
Abstract
The development of suitable biomimetic three-dimensional scaffolds is a fundamental requirement of tissue engineering. This paper presents the first successful attempt to obtain electrospun gelatin nanofibers cross-linked with a low toxicity agent, genipin, and able to retain the ori...
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PMID: 21095244
PDF is available here.
Abstract
We developed microfibrous scaffolds made from blends of PGS and poly(ε-caprolactone) (PCL) using a standard electrospinning set-up. At a given PGS:PCL ratio, higher voltage resulted in significantly smaller fibre diameters (reduced from ∼4 µm to 2.8 µm; p < 0.05). Further increase in voltage re...
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PMID: 20669260
PDF is available here.
Abstract
To analyze the distribution of stresses at the bond interface of Molloplast-B soft-liner attached to PMMA acrylic surface of different geometries (smooth and rough) and at different load-application distances by 3D-FEA modeling of typical shear-bond test. Methodology Three-dimensional finite element...
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PMID: 21354607
PDF is available here.
Abstract
To investigate the mechanical properties of injection-molded thermoplastic denture base resins.
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PMID: 20873995
PDF is available here.
Abstract
The paper compares the compressibility of two directly compressible isomalts, galenIQ 720 and galenIQ721, using the energy evaluation of the compaction process by means of the force--displacement profiles. It evaluates the energies for friction, energies accumulated by the tablet, energy of decompres...
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PMID: 21648171
PDF is available here.
Abstract
Poly(lactide-co-glycolide) (PLGA) beads have been widely studied as a potential drug/protein carrier. The main shortcomings of PLGA beads are that they lack bioactivity and controllable drug-delivery ability, and their acidic degradation by-products can lead to pH decrease in the vic...
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PMID: 21210517
PDF is available here.
Abstract
Synthetic implant materials often lack of the anisotropic mechanical properties and cell-interactive surface which are shown by natural tissues. For example, engineered vascular grafts need to be developed to address the mechanical and biological problems associated with the graft ma...
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PMID: 21210507
PDF is available here.
Abstract
Based on the universal laws of mechanics and physical chemistry, physiology build mechanical models of teeth, which allowed to explain the role of mastication in the mechanism of demineralization and remineralization of hard tissues of teeth and asymmetry of erasing their working surfaces. In the pro...
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PMID: 21716242
PDF is available here.
Abstract
We describe how cell-seeded Type-I collagen gels can be adapted to provide powerful 3D models to support a wide range of research applications where cell/substrate alignment, density, stiffness/compliance, and strain are critical factors. In their fully hydrated form, rectangular collagen gels can b...
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PMID: 21042973
PDF is available here.
Abstract
We have synthesized a hydrophilic biodegradable polymer, designated poly(glucose malate)methacrylate (PGMma), which is composed of glucose and malic acid, commonly found in the human metabolic system. This polymer is made photocrosslinkable by the incorporation of methacrylate groups. The resulting...
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PMID: 20647064
PDF is available here.
Abstract
Repair of load-bearing defects resulting from disease or trauma remains a critical barrier for bone tissue engineering. Calcium phosphate (CaP) scaffolds are among the most extensively studied for this application. However, CaPs are reportedly too weak for use in such defects and, th...
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PMID: 20655397
PDF is available here.
Abstract
We have developed a synthetic vascular conduit for small-diameter applications. We show that tropoelastin enhances endothelial cell attachment (threefold vs. control) and proliferation by 54.7 ± 1.1% (3 days vs. control). Tropoelastin, when presented as a monomer and when cross-linked into syntheti...
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PMID: 20656079
PDF is available here.
Abstract
Biological scaffolds used in tissue engineering are incorporated in vivo by a process of cellular in-growth, followed by host-mediated degradation and replacement of these scaffolds, in which phagocytic cells from the monocyte/macrophage cell lineage play a key role. The chemical deg...
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PMID: 20709200
PDF is available here.
Abstract
A periodontal membrane with a graded structure allows tailoring of the layer properties to design a material system that will retain its physical, chemical and mechanical characteristics for a period long enough to optimize periodontal regeneration. In this work a novel functionally...
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PMID: 20801241
PDF is available here.
Abstract
Polymeric endoaortic paving (PEAP) is a process by which a polymer is endovascularly delivered and thermoformed to coat or "pave" the lumen of the aorta. This method may offer an improvement to conventional endoaortic therapy in allowing conformal graft application with reduced risk...
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PMID: 20832506
PDF is available here.
Abstract
We present the focused development of a novel structure that combines the biomimetic properties of nanofibers with the robust mechanical aspects of the sintered microsphere scaffold to produce a composite scaffold that demonstrates an ability to mimic the mechanical environment of trabecular bone wh...
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PMID: 20878987
PDF is available here.
Abstract
Our objective was to investigate the properties of a three-dimensional silk sericin and PVA scaffold with and without glycerin and genipin at various concentrations. SEM showed that adding glycerin into scaffold gave better uniformity and porosity. Smaller pore sizes and better uniformity were found...
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PMID: 20804781
PDF is available here.
Abstract
Bionanocomposites formed by combining biodegradable polymers and nanosized osteoconductive inorganic solids have been regarded as promising biomimetic systems which possess much improved structural and functional properties for bone tissue regeneration. In this study three-dimensiona...
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PMID: 20601244
PDF is available here.
Abstract
These results suggest the presence of multiple mechanisms as causes for increasing hydrogel modulus with freeze-thaw cycling, including hydrogen bonding between amorphous and/or crystalline regions, and the formation of highly concentrated regions of mostly amorphous PVA chains. It is possible that...
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PMID: 20601243
PDF is available here.
Abstract
We performed serial MPM and mechanical tests on acellular and cellularized (normal human lung fibroblasts) collagen hydrogels, before and after glutaraldehyde crosslinking. Following gel contraction over 16 days, cellularized collagen gel content approached that of native connective tissues (∼200...
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PMID: 20620246
PDF is available here.
Abstract
We show that despite the highly ordered structure and tacticity-dependent nature of hydrogen-bonded supramolecular polymers, the bioactivity of these polymers can be tuned through composite preparation with bioceramics. These novel supramolecular composites combine the superior processability of sup...
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PMID: 20574978
PDF is available here.
Abstract
We thus assess the potential of decellularized porcine myocardium as a scaffold for thick cardiac patch tissue engineering. Myocardial sections with 2-mm thickness were decellularized using 0.1% sodium dodecyl sulfate and then reseeded with differentiated bone marrow mononuclear cells. We found that...
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PMID: 20694977
PDF is available here.
Abstract
Mechanical stiffness is a fundamental parameter in the rational design of composites for bone tissue engineering in that it affects both the mechanical stability and the osteo-regeneration process at the fracture site. A mathematical model is presented for predicting the effective Yo...
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PMID: 20346422
PDF is available here.
Abstract
The cross-sectional design has a greater impact than taper or size of the instrument on the stresses developed in the instrument under either torsion or bending. Certain cross-sectional configurations are prone to fracture by excess torsional stresses.
Copyright 2010 American Association of Endodo...
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PMID: 20647104
PDF is available here.
Abstract
The two simulated conditions highlighted the different mechanical properties of the files; the SystemGT showed slightly better performances under flexural solicitation, whereas the Protaper presented better behavior under torsion solicitations.
Copyright 2010 American Association of Endodontists. P...
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PMID: 20647101
PDF is available here.
Abstract
Spiders and silkworms generate silk protein fibers that embody strength and beauty. Orb webs are fascinating feats of bioengineering in nature, displaying magnificent architectures while providing essential survival utility for spiders. The unusual combination of high strength and extensibility is a...
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PMID: 20671180
PDF is available here.
Abstract
Phosphate-based glasses (PGs) and their composites are of interest as bone repair and tissue engineering scaffolds due to the totally degradable nature of the materials. This study has investigated the effect of Si and Fe on the properties of PG particulate-filled polycaprolactone (P...
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PMID: 20206722
PDF is available here.
Abstract
Phosphate-based glasses (PGs) and their composites are of interest as bone repair and tissue engineering scaffolds due to the totally degradable nature of the materials. This study has investigated the effect of Si and Fe on the properties of PG particulate-filled polycaprolactone (P...
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PMID: 20206722
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Thin-film membranes consisting of nanoparticles are of interest in applications ranging from nanosieves to electric, magnetic, or photonic devices and sensors. However, the fabrication of large-scale membranes in a simple but controlled way has remained a challenge, due to the limite...
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PMID: 20521265
PDF is available here.
Abstract
Over the past decade, it has been increasingly recognized that both chemical and mechanical properties of scaffolds influence neural cell behavior, ranging from growth to differentiation to migration. However, mechanical properties are difficult to control for in the design of scaffo...
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PMID: 20401966
PDF is available here.
Abstract
The aim of this study is to determine some physical and mechanical properties of Paulownia tomentosa wood grown in Turkey. The samples trees harvested from Kargi in Corum. Physical properties including air-dry density oven-dry density basic density swelling, shrinkage and oven-dry and air-dry therma...
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PMID: 21047010
PDF is available here.
Abstract
Magnesium alloys have attracted increasing interest in the past years due to their potential as implant materials. This interest is based on the fact that magnesium and its alloys are degradable during their time of service in the human body. Moreover magnesium alloys offer a property profile that i...
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PMID: 19788945
PDF is available here.
Abstract
We describe the production of scaffold-free stiff cartilaginous tissue of pig and human, using allogeneic serum and growth factors. The tissue was formed in a mold using chondrocytes recovered from alginate bead culture and maintained in a medium with transforming growth factor-beta and several othe...
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PMID: 19938962
PDF is available here.
Abstract
Creating autologous tissues with on-demand and native-like biomechanical properties is the ultimate challenge in functional heart valve tissue engineering. A promising approach toward this goal is to induce development of native-like tissue structure in vitro by mimicking the diastol...
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PMID: 20001249
PDF is available here.
Abstract
Our VE's permeability to (14)C-urea was significantly similar to porcine bladder, and characterization of the mechanical properties indicated that our tissue could be suitable for grafting since its ultimate tensile strength compares favorably with a native porcine bladder.
The const...
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PMID: 20014996
PDF is available here.
Abstract
Wild tall wheatgrass (Lophopyrum elongatum L., 2x = 14) is an important resource for improving bread wheat (Titicum aestivum L.), including HMW-GS and LMW-GS relevant to end-use quality of the wheat flour. A set of 14 distinct sequences were amplified from the genomic DNA of the tall wheatgrass, usi...
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PMID: 19484339
PDF is available here.
Abstract
Mechanical fractionation and aqueous or aqueous/organic two-phase partition approaches were applied for extraction and separation of extracellular terpenoid hydrocarbons from Botryococcus braunii var. Showa. A direct spectrophotometric method was devised for the quantitation of botryococcene and ass...
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PMID: 20005092
PDF is available here.
Abstract
The demand for mouth dissolving tablets has been growing during the last decade especially for elderly and children who have swallowing difficulties. Etoricoxib is a new non-steroidal anti-inflammatory drug (NSAID) with selective cox-2 inhibitory activity, selective inhibition of cox-2 provides anti...
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PMID: 20363696
PDF is available here.
Abstract
Ophthalmic delivery systems such as ocular inserts are useful strategies to improve the ocular bioavailability of topically administered drugs. In the present study polyvinyl alcohol and sodium carboxymethylcellulose based ocular inserts were prepared by solution casting for sustained drug delivery...
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PMID: 19900594
PDF is available here.
Abstract
We have developed novel poly(diol citrate) elastomers, which are capable of providing localized and sustained release of nitric oxide (NO). The elastomer prepolymer was obtained by condensation of citric acid, 1,8-octanediol, and N,N'-bis(2-hydroxyethyl)ethylenediamine at 130 degrees C for 40 min. F...
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PMID: 19569216
PDF is available here.
Abstract
We consider dextrin a promising biomaterial for biomedical applications, namely for controlled release....
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PMID: 19569221
PDF is available here.
Abstract
We review these strategies and describe applications of them in systems ranging from electronic eyeball cameras to deformable light-emitting displays. We conclude with some perspectives on routes to commercialization, new device opportunities, and remaining challenges for research....
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PMID: 20339064
PDF is available here.
Abstract
We report here two self-replicating peptide-derived macrocycles that emerge from a small dynamic combinatorial library and compete for a common feedstock. Replication is driven by nanostructure formation, resulting from the assembly of the peptides into fibers held together by beta sheets. Which of...
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PMID: 20299594
PDF is available here.
Abstract
Collagen-based vascular substitutes represent in VTE a valid alternative for the replacement of diseased small-calibre blood vessels. In this study, collagen gel-based scaffolds were crosslinked combining modulation of pH and UV-C radiation. The effects on the mechanical properties,...
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PMID: 19946859
PDF is available here.
Abstract
Two ready-to-eat minced fish products from hake were developed, their proximate composition and fatty acid profiles determined and their quality changes followed during 3.5 months under refrigeration at 2 ± 1 °C and 10 ± 1 °C. These products contain dietary fiber and are innovati...
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PMID: 21339119
PDF is available here.