Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Time Factors (0):
Recent article
Time Factors
Abstract
We describe the magnitude, kinetics, and nature of the virus-specific T cell response using intracellular gamma interferon (IFN-γ) staining and fluorochrome-labeled major histocompatibility complex (MHC) class I-peptide complexes. We demonstrate that influenza virus-infected patients develop recall...
|
PMID: 21917970
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
We established a new limited sampling strategy to assess CYP3A activity and evaluated the time course of reversible (voriconazole) and irreversible (ritonavir) CYP3A inhibition. In this randomized trial, two groups, each with eight healthy participants, received CYP3A inhibitors voriconazole or riton...
|
PMID: 21937987
PDF is available here.
PDF is available here.
Abstract
We studied the effect of exercise training on islet and β-cell morphology and plasma insulin and glucose, following an intraperitoneal glucose tolerance test (IPGTT) in juvenile and adult male Wistar-Kyoto rats born small. Bilateral uterine vessel ligation performed on day 18 of pregnancy resulted...
|
PMID: 21810930
PDF is available here.
PDF is available here.
Abstract
We studied the impact of early pancreas graft failure on long-term kidney and patient survival. METHODS.: We included all primary SPK transplants performed in the United States between January 1, 2000, and December 31, 2007, who had maintained kidney graft function at 90 days posttransplantation. Ka...
|
PMID: 21832957
PDF is available here.
PDF is available here.
Abstract
We show, in humans and rhesus monkeys, that a transcortical pathway through primary motor cortex (M1) resolves this ambiguity during fast feedback control. We demonstrate that single M1 neurons of behaving monkeys can integrate shoulder and elbow motion information into motor commands that appropria...
|
PMID: 21964335
PDF is available here.
PDF is available here.
Abstract
We have developed methods to coculture osteoblasts, which are the primary cell type making up bone, and endothelial cells, which form the vasculature supplying cells in the bone with oxygen and nutrients to survive on 2- and 3-D biomaterials....
|
PMID: 21042976
PDF is available here.
PDF is available here.
Abstract
We have analyzed the Society for Cardiothoracic Surgery in Great Britain and Ireland audit database to look at changes in practice over time....
|
PMID: 21924147
PDF is available here.
PDF is available here.
Abstract
We hypothesize that UCHL1 would be an effective serum biomarker for brain injury as tested in canine models of hypothermic circulatory arrest (HCA) and cardiopulmonary bypass (CPB)....
|
PMID: 21924148
PDF is available here.
PDF is available here.
Abstract
The individual benefit from cardiac resynchronisation therapy (CRT) varies largely among patients.
|
PMID: 21821856
PDF is available here.
PDF is available here.
Abstract
To assess the incidence of conduction disturbances leading to permanent pacemaker implantation (PPI) following isolated aortic valve replacement (AVR) in a large cohort of elderly patients with severe symptomatic aortic stenosis, and to determine the predictive factors and prognostic value of PPI fol...
|
PMID: 21828221
PDF is available here.
PDF is available here.
Abstract
We examined the ability of the Verigene CLO assay (Nanosphere, Northbrook, IL) to identify CYP2C19 (*)2 and (*)3 polymorphisms in 1,286 unique whole blood samples. The Verigene CLO assay accurately identified homozygous and heterozygous (*)2 and (*)3 phenotypes with a specificity of 100% and a final...
|
PMID: 21917683
PDF is available here.
PDF is available here.
Abstract
We investigated whether preoperative ingestion of a glucose solution interferes with fasting-induced protection against renal I/R injury. METHODS.: Mice were randomized into the following groups: fasted for 3 days with access to water (fasted) or a glucose solution (fasted+glc) and fed ad libitum wi...
|
PMID: 21926943
PDF is available here.
PDF is available here.
Abstract
Capsaicin β-glucoside was isolated from the feces of Helicoverpa armigera, Helicoverpa assulta, and Helicoverpa zea that fed on capsaicin-supplemented artificial diet. The chemical structure was identified by NMR spectroscopic analysis as well as by enzymatic hydrolysis. The excretion rates of the g...
|
PMID: 21928395
PDF is available here.
PDF is available here.
Abstract
We analyzed these possible confounders and their relation to overall survival....
|
PMID: 21843923
PDF is available here.
PDF is available here.
Abstract
Currently, the main hurdle in the tissue engineering field is how to provide sufficient blood supply to grafted tissue substitutes in the early post-transplanted period. For three-dimensional, cell-dense, thick tissues to survive after transplantation, treatments are required for hyp...
|
PMID: 21548841
PDF is available here.
PDF is available here.
Abstract
Recent pre-clinical and clinical studies indicate that certain exogenous stem cells and biomaterials can preserve cardiac tissue after myocardial infarction. Regarding stem cells, a growing body of data suggests that the short-term positive outcomes are mainly attributed to paracrine...
|
PMID: 21735303
PDF is available here.
PDF is available here.
Abstract
I at varying ratios. Maturation of cardiac function in embryoid bodies formed from hESCs was documented in terms of spontaneous contractile behavior and the mRNA and protein expression of cardiac markers. Hydrogel with high ECM content (75% ECM, 25% collagen, no supplemental soluble factors) increas...
|
PMID: 21744185
PDF is available here.
PDF is available here.
Abstract
We measured the effect of variations in scaffold stiffness on the expression of extracellular matrix molecules specific to the NP (proteoglycans and collagen) by native NP cells. We prepared sample discs of different concentrations of alginate (1%-6%) by two different methods, diffusion and in situ...
|
PMID: 21783128
PDF is available here.
PDF is available here.
Abstract
Tissue engineering promises to restore tissue and organ function following injury or failure by creating functional and transplantable artificial tissues. The development of artificial tissues with dimensions that exceed the diffusion limit (1-2 mm) will require nutrients and oxygen...
|
PMID: 21892744
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)10 2011
Abstract
In this study, a two-part bone tissue engineering scaffold was investigated. The scaffold consists of a solid poly(propylene fumarate) (PPF) intramedullary rod for mechanical support surrounded by a porous PPF sleeve for osseointegration and delivery of poly(dl-lactic-co-glycolic aci...
|
PMID: 21757034
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)10 2011
Abstract
These results correlate with measurements of the mechanical properties of the scaffolds, since both the ultimate tensile strength and tensile modulus of the cell seeded scaffolds had increased by the end of the culture period. This experiment demonstrates that porcine and avian collagen could be use...
|
PMID: 21723967
PDF is available here.
PDF is available here.
Abstract
Abstract
Patients undergoing elective percutaneous coronary intervention (PCI) are generally observed overnight in the hospital. The association between same-day discharge of older patients and death or readmission is unclear.
To evaluate the prevalence and outcomes of same-da...
|
PMID: 21972308
PDF is available here.
PDF is available here.
Abstract
Orvosi Hetilap (152)41 2011
Abstract
Twenty-six documents were identified: 4 in England, 2 in Finland, 9 in Germany, 6 in Hungary and 5 in Spain. Altogether 203 statements linked to references were identified: benefits of breast-feeding in general (24%), protection against infections (32%), long-term advantages like the prevention of d...
|
PMID: 21959937
PDF is available here.
PDF is available here.
Abstract
We present our early experience with an attempt to optimize extracorporeal membrane oxygenation, emphasizing reduced adjunctive mechanical ventilatory support and aggressive rehabilitation, with a goal of ambulation. This strategy has been enabled by the introduction of a dual-lumen draw and return...
|
PMID: 21924145
PDF is available here.
PDF is available here.
Abstract
We show that labile S4 complexes rearrange into stable complexes within a few minutes at 42 °C, with longer coincubation leading to an increased population of stable complexes. In contrast, prefolding the rRNA has a smaller effect on stable S4 binding. Experiments with minimal rRNA fragments show...
|
PMID: 21821049
PDF is available here.
PDF is available here.
Orvosi Hetilap (152)40 2011
Abstract
Therapeutic methotrexate serum concentrations (30-100µmol/l) were achieved in 72.5% of the cases. Repeated treatments resulted similar serum levels. Hepatotoxicity and hypoproteinemia occurred in 17% and in 48.9% of the cases. There was significant correlation between serum 7-hydroxi-methotrexate a...
|
PMID: 21945870
PDF is available here.
PDF is available here.
Abstract
We expected that a substantial proportion of patients staying in Norwegian hospitals would report postoperative pain of high intensity....
|
PMID: 21946593
PDF is available here.
PDF is available here.
Abstract
Abstract
Multiple lines of evidence from a total of six sets of safety data, with treatment for up to 5 years, including results from all adalimumab-treated patients, and a subset of patients treated with 40 mg eow dosing, did not show evidence of cumulative toxicity, and showed adverse event rates that we...
|
PMID: 21834597
PDF is available here.
PDF is available here.
New England Journal of Medicine (365)12 2011
Abstract
We hypothesized that a long interdialytic interval is associated with adverse events in patients receiving hemodialysis.
We studied 32,065 participants in the End-Stage Renal Disease Clinical Performance Measures Project, a nationally representative sample of U.S. patients receiving...
|
PMID: 21992122
PDF is available here.
PDF is available here.
Abstract
About 190,000 Germans experience a myocardial infarction each year. Of these, 25% may be eligible for an implantable cardioverter defibrillator (ICD) due to low left ventricular ejection fraction. Given the high costs of implantation, the purpose of this study was to assess the cost-effectiveness of...
|
PMID: 21914500
PDF is available here.
PDF is available here.
Abstract
Determination of the prevalence of accumulated antiretroviral drug resistance among persons infected with human immunodeficiency virus (HIV) is complicated by the lack of routine measurement in clinical care. By using data from 8 clinic-based cohorts from the North American AIDS Cohort Collaboration...
|
PMID: 21813792
PDF is available here.
PDF is available here.
Abstract
The study objective was to determine the relation of prenatal smoking exposure to the use of psychotropic medication up to young adulthood by using population-based longitudinal register data consisting of all singletons born in Finland from 1987 to 1989 (n = 175,869). Information on maternal smoking...
|
PMID: 21821539
PDF is available here.
PDF is available here.
Abstract
The authors prospectively examined the association between the Dietary Approaches to Stop Hypertension diet score, overall, animal-based, and vegetable-based low-carbohydrate-diet scores, and major plant food groups and the risk of postmenopausal breast cancer in 86,621 women in the Nurses' Health St...
|
PMID: 21832271
PDF is available here.
PDF is available here.
Abstract
We examine a scenario in which the isotopic signal, as well as the global glaciation, result from enhanced export of organic matter from the upper ocean into anoxic subsurface waters and sediments. The organic matter undergoes anoxic remineralization at depth via either sulfate- or iron-reducing bac...
|
PMID: 21825156
PDF is available here.
PDF is available here.
Abstract
Prospective studies on the role of psychosocial factors in heart failure development are virtually nonexistent. The authors aimed to address the effect of psychosocial factors on the risk of heart failure hospitalization in men and women free of cardiovascular disease. In 1991-1993, the 8,670 partici...
|
PMID: 21821541
PDF is available here.
PDF is available here.
Missouri medicine (108)4 2011
Abstract
We summarize data on the economic consequences of liver and renal allograft quality in contemporary practice. Policy makers and providers must work together to ensure that financial disincentives do not lead to wastage of lifesaving organs....
|
PMID: 21905445
PDF is available here.
PDF is available here.
Abstract
Mesothelioma is considered a signal tumor for asbestos exposure and typically occurs decades after first exposure to asbestos. Tissue analysis often indicates past exposure to mixed types of asbestos. This report describes the case of a 58-year-old man who developed mesothelioma after reported exposu...
|
PMID: 21905385
PDF is available here.
PDF is available here.
Abstract
Inhalational induction with Halothane is commonly used for anaesthesia in children. Its drawbacks include bradycardia and hypotension. Intravenous propofol has recently challenged this position.
|
PMID: 21913547
PDF is available here.
PDF is available here.
Circulation (124)11 Suppl 2011
Abstract
We previously showed that adenoviral-delivered overexpression of an endogenous inhibitor, the tissue inhibitor of metalloproteinases-3 (TIMP-3), significantly retarded intimal thickening in short-term autologous porcine arteriovenous interposition grafts (28 days). However, it is essential to determ...
|
PMID: 21911803
PDF is available here.
PDF is available here.
Circulation (124)11 Suppl 2011
Abstract
We therefore aimed to generate a hypoantigeneic hESC line with improved survival characteristics.
Using various in vivo, nonischemic, hindlimb xenotransplant models (immunocompetent and defined immunodefective mouse strains) as well as human in vitro T-cell and natural killer (NK)-ce...
|
PMID: 21911816
PDF is available here.
PDF is available here.
Abstract
In this paper, a pH-inductive protein-scaffold biosynthesis of shape-tunable crystalline gold nanoparticles at room temperature has been developed. By simple manipulation of the reaction solution's pH, anisotropic gold nanoparticles including spheres, triangles and cubes could be produced by incubati...
|
PMID: 21828895
PDF is available here.
PDF is available here.
Abstract
Varicella may have a serious and sometimes fatal course, especially in immunocompromised patients. Some patient groups may need prophylaxis after exposure to the varicella-zoster-virus. In this article we review the evidence for usefulness of prophylactic measures after such exposure.
|
PMID: 21901036
PDF is available here.
PDF is available here.
Veterinary Record (169)10 2011
Abstract
The use of injectable transponders in cattle for identification purposes, for up to 30 months, was investigated. Passive electronic transponders, encapsulated in either polymer or glass, were injected subcutaneously into either the ear base or the earlobe of 652 calves in three populations. The anima...
|
PMID: 21813580
PDF is available here.
PDF is available here.
Abstract
Extending intravenous thrombolysis to a broader patient population, clarifying the risk and benefits of intra-arterial reperfusion therapies, and further development of neuroprotective therapies were the key recommendations from STAIR VII....
|
PMID: 21852620
PDF is available here.
PDF is available here.
Abstract
We conclude that IV zanamivir as late add-on therapy has limited effectiveness. The effect of an immediate start with IV zanamivir monotherapy or in combination with other drugs need to be evaluated....
|
PMID: 21844304
PDF is available here.
PDF is available here.
Abstract
Previous studies demonstrated the effectiveness of selective σ-receptor (σR) agonists [1,3-di-o-tolylguanidine (DTG), PRE-084] as reinforcers in rats trained to self-administer cocaine. Similar to cocaine, these drugs increased nucleus accumbens shell dopamine levels, and effects of DTG, but not PR...
|
PMID: 21808192
PDF is available here.
PDF is available here.
Abstract
Salvinorin A, the main active component of Salvia divinorum, is a potent and selective κ opioid receptor agonist. Synthetic derivatives of this substance may be useful in the development of medicinal treatments for pain, mood disorders, and drug dependence. Such developments require extensive precli...
|
PMID: 21814135
PDF is available here.
PDF is available here.
Abstract
We examined four different cannabinergic aminoalkylindole ligands, including one drug (AM678=JWH018) found in herbal 'Spice' concoctions, for their ability to substitute for Δ-tetrahydrocannabinol (THC), and the ability of the cannabinoid receptor 1-selective antagonist/inverse agonist rimonabant to...
|
PMID: 21836461
PDF is available here.
PDF is available here.
Abstract
Competition theory predicts that multispecies coexistence requires that species have traits that fall on the same interspecific trade-off surface. Fossil records for mollusks, mammals, trees, and other taxa show that with rare exception, ecologically similar species have coexisted for a million years...
|
PMID: 21828992
PDF is available here.
PDF is available here.
Abstract
A study on biofilm formation was carried out using five methicillin-sensitive [MSSA] and five methicillin-resistant [MRSA] strains of S. aureus. In each group, there were four strains isolated from patients from Kinshasa (Democratic Republic of Congo, DRC) and one reference strain. All of the strains...
|
PMID: 21810033
PDF is available here.
PDF is available here.
Abstract
We could not identify any clinical difference between INT and RY after total gastrectomy 60 months after surgery. The safer and simpler RY method may be a more suitable reconstruction method than INT after total gastrectomy.
Copyright © 2011. Published by Elsevier Inc....
|
PMID: 21871978
PDF is available here.
PDF is available here.
Abstract
Complex hepatobiliary surgical procedures for benign and malignant conditions are regularly performed at tertiary academic referral centers with excellent outcomes, but whether similar surgical outcomes are achievable in community hospitals is not well documented.
Eig...
|
PMID: 21871981
PDF is available here.
PDF is available here.
Abstract
Ultralow anterior resection for mid and distal rectal cancers has been reported routinely performed using either a laparoscopic ultralow anterior resection (LAR) or laparoscopic pull-through with coloanal anastomosis (LPT). This study evaluated the postoperative and functional outcom...
|
PMID: 21871983
PDF is available here.
PDF is available here.
Abstract
Different risk-prediction models have been developed, but none is generally accepted in selecting patients for esophagectomy. This study evaluated 5 most frequently used risk-prediction models, including the American Society of Anesthesiologists, Portsmouth-modified Physiological and...
|
PMID: 21871985
PDF is available here.
PDF is available here.
Abstract
NMDA at P10-15 (the rat "infant" period) triggers the spasms significantly earlier and in greater numbers in the prenatal betamethasone-exposed brain compared to controls. Similar to human condition, the spasms occur in clusters. Repeated trigger of spasms is associated with ictal EEG electrodecr...
|
PMID: 21854372
PDF is available here.
PDF is available here.
Abstract
Background. Central nervous system (CNS) human immunodeficiency virus (HIV) infection and immune activation lead to brain injury and neurological impairment. Although HIV enters the nervous system soon after transmission, the magnitude of infection and immunoactivation within the CNS during primary...
|
PMID: 21844301
PDF is available here.
PDF is available here.
Abstract
African American ethnicity is a well-described negative predictor of treatment outcome for chronic hepatitis C (CHC); however, less is known about the influence of Hispanic and Asian ethnicity. The aim of this subanalysis of the Weight-based Dosing of PegINterferon α-2b and Ribavirin (WIN-R) study w...
|
PMID: 21836471
PDF is available here.
PDF is available here.