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All › Animals › Animal Population Groups › Chimera

Chimera (1)

    Articles on Chimera

    1. Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model.
      Tai T Yi, Birgit B Fogal, ... Jordan S JS Pober

      Arterioscler Thromb Vasc Biol 32(2):353-60 (2012) PMID 22053072 PMCID PMC3262100

      We have developed a model for studying this process using human materials. Human artery segments were transplanted as infrarenal aortic interposition grafts into an immunodeficient mouse host, allowed to "heal in" for 30 days, and then retransplanted into a second mouse host. To indu...
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    2. Generation of chimeric rhesus monkeys.
      Masahito M Tachibana, Michelle M Sparman, ... Shoukhrat S Mitalipov

      Cell 148(1-2):285-95 (2012) PMID 22225614

      We demonstrate that rhesus monkey embryonic stem cells (ESCs) and isolated ICMs fail to incorporate into host embryos and develop into chimeras. However, chimeric offspring were produced following aggregation of totipotent cells of the four-cell embryos. These results provide insights into the speci...
    3. Establishment and characterization of hepatocytes from an Immortomouse/SMP30/GNL knockout mouse hybrid lacking vitamin C to study vitamin C ...
      Akiko A Amano, Setsuko S Handa, ... Akihito A Ishigami

      J Biol Chem 150(6):671-8 (2011) PMID 21903636

      We previously reported the development of SMP30/GNL knockout (KO) mice unable to synthesize AA in vivo. For more efficient study of the liver's AA uptake and as yet uncharacterized efflux system, we established an immortal hepatocyte line derived from a hybrid of SMP30/GNL KO mice and Immortomice. I...
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    4. Short day-mediated cessation of growth requires the downregulation of AINTEGUMENTALIKE1 transcription factor in hybrid aspen.
      Anna A Karlberg, Laszlo L Bako, and Rishikesh P RP Bhalerao

      PLoS Genet 7(11):e1002361 (2011) PMID 22072988

      We show that the AIL1-AIL4 (AINTEGUMENTALIKE) transcription factors of the AP2 family are the downstream targets of the SD signal in the regulation of growth cessation response in hybrid aspen trees. AIL1 is expressed in the shoot apical meristem and leaf primordia, and exposure to SD signal downreg...
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    5. Hybridization experiments indicate incomplete reproductive isolating mechanism between Fasciola hepatica and Fasciola gigantica.
      T Itagaki, M Ichinomiya, ... C Carmona

      Parasitology 138(10):1278-84 (2011) PMID 21767436

      Experiments on hybridization between Fasciola hepatica and Fasciola gigantica were carried out to clarify whether a reproductive isolating mechanism appears between the two Fasciola species. Molecular evidence for hybridization was based on the DNA sequence of the internal transcribe...
    6. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
      David L DL Porter, Bruce L BL Levine, ... Carl H CH June

      N Engl J Med 365(8):725-33 (2011) PMID 21830940 PMCID PMC3387277

      We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with CD137 (a costimulatory receptor in T cells [4-1BB]) and CD3-zeta (a signal-transduction component of the T-cell antigen receptor) signaling domains. A low dose (approxima...
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    7. [2011: a wave of chimeras in England].
      Jean-Yves JY Nau

      Rev Med Suisse 7(305):1596-7 (2011) PMID 21922727

    8. Evidence for human lung stem cells.
      Yuben Y Moodley

      N Engl J Med 365(5):464; author reply 465-6 (2011) PMID 21812680

    9. Interspecies chimera between primate embryonic stem cells and mouse embryos: monkey ESCs engraft into mouse embryos, but not post-implantati...
      Calvin C Simerly, Dave D McFarland, ... Gerald G Schatten

      Stem Cell Res 7(1):28-40 (2011) PMID 21543277

      Unequivocal evidence for pluripotency in which embryonic stem cells contribute to chimeric offspring has yet to be demonstrated in human or nonhuman primates (NHPs). Here, rhesus and baboons ESCs were investigated in interspecific mouse chimera generated by aggregation or blastocyst...
    10. Electrochemical impedance determination of polychlorinated biphenyl using a pyrenecyclodextrin-decorated single-walled carbon nanotube hybri...
      Yan Wei, Ling-Tao Kong, ... Xing-Jiu Huang

      Chem Commun (Camb) 47(18):5340-2 (2011) PMID 21451857

      This work reports the first detailed study on an electrochemical impedance sensor for determination of polychlorinated biphenyl (PCB), such as 3,3',4,4'-tetrachlorobiphenyl (PCB-77), based on a single-walled carbon nanotube/pyrenecyclodextrin (SWCNT/PyCD) hybrid. © T...