Saul A Villeda,
Jian Luo,
Kira I Mosher,
Bende Zou,
Markus Britschgi,
Gregor Bieri,
Trisha M Stan,
Nina Fainberg,
Zhaoqing Ding,
Alexander Eggel,
Kurt M Lucin,
Eva Czirr,
Jeong-Soo Park,
Sebastien Couillard-Després,
Ludwig Aigner,
Ge Li,
Elaine R Peskind,
Jeffrey A Kaye,
Joseph F Quinn,
Douglas R Galasko,
Xinmin S Xie,
Thomas A Rando and
Tony Wyss-Coray
Abstract
We show that blood-borne factors present in the systemic milieu can inhibit or promote adult neurogenesis in an age-dependent fashion in mice. Accordingly, exposing a young mouse to an old systemic environment or to plasma from old mice decreased synaptic plasticity, and impaired contextual fear con...
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PMID: 21886162
PDF is available here.
Abstract
Recreation has the potential to be an important public policy priority; however, it must be reframed to address critical policy priorities.
Copyright © 2011 Wiley Periodicals, Inc., A Wiley Company.
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PMID: 21786415
PDF is available here.
Abstract
We present a model of plasticity induction for reinforcement learning in a population of leaky integrate and fire neurons which is based on a cascade of synaptic memory traces. Each synaptic cascade correlates presynaptic input first with postsynaptic events, next with the behavioral decisions and f...
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PMID: 21738460
PDF is available here.
Abstract
Dynamic chromatin remodeling is at the heart of most biological processes including gene transcription, DNA replication and repair, cell differentiation and apoptosis. Chromatin remodeling as a result of covalent histone modifications, including histone acetylation, methylation or SU...
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PMID: 21586900
PDF is available here.
Abstract
Zebra finches produce a learned song that is rich in harmonic structure and highly stereotyped. More is generally known about how birds learn and produce this song than how they perceive it. Here, zebra finches were trained with operant techniques to discriminate changes in natural and synthetic song...
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PMID: 21568438
PDF is available here.
Abstract
To implement a Learning Bridge tool to improve educational outcomes for pharmacy students as well as for preceptors and faculty members.
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PMID: 21655400
PDF is available here.
Abstract
We report that either deafferentation or reduction of sensory input by nares occlusion significantly reduced GAD67 protein and the number of SA cells expressing GAD67. However, neither manipulation altered GAD65 protein or the number of GAD65 PG cells. These findings show that sensory experience str...
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PMID: 21276774
PDF is available here.
Abstract
We construct a simple but biologically reasonable model based on the experimental results of two frogs, extend the model to a system of three frogs, and theoretically predict the occurrence of rich synchronization phenomena, such as triphase synchronization and 1:2 antiphase synchronization. In addi...
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PMID: 21517531
PDF is available here.
Abstract
It is unknown whether surgical residents who learn minimal-access surgery skills in an unstructured environment (ie, at home), will develop a technical skill set that rivals that of those trained in the more traditional, structured learning environment.
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PMID: 21367370
PDF is available here.
Abstract
This study aimed to describe health science university students' experiences of group supervision of the bachelor's thesis. Sixty-one students responded to questions on an open data collection form, and the data were analyzed by using qualitative inductive content analysis. According to the students,...
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PMID: 21366166
PDF is available here.
Abstract
To incorporate Fink's Taxonomy of Significant Learning into a course and determine whether doing so increased students' knowledge of and interest in healthcare policy.
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PMID: 21451768
PDF is available here.
Abstract
We show how to implement ADP methods using only measured input/output data from the system. Linear dynamical systems with deterministic behavior are considered herein, which are systems of great interest in the control system community. In control system theory, these types of methods are referred t...
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PMID: 20350860
PDF is available here.
Abstract
To explore relevant between human cytomegalovirus (HCMV) infection and college students' neurobehaviors.
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PMID: 21789857
PDF is available here.
Abstract
Contemporary practices in nursing education call for changes that will assist students in understanding a complex, rapidly changing world. Narrative pedagogy is an approach that offers teachers a way to actively engage students in the process of teaching and learning. The narrative approach provides...
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PMID: 21323257
PDF is available here.
Abstract
Many nurses have difficulty learning to use the complex, non-traditional, and regularly-updated critical care equipment. Failure to use such equipment properly can seriously compromise treatment and endanger patient health and lives. New self-learning materials for novice nurses are necessary to prov...
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PMID: 21328204
PDF is available here.
Abstract
The literature continues reporting a high complication rate for carotid artery stenting (CAS) during the learning-curve phase (LCP). The aim of this study was to report a simple and reproducible method designed to improve CAS results during the LCP.
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PMID: 21224812
PDF is available here.
Abstract
We provide evidence that BLA is necessary for the synaptic strengthening occurring during memory formation in the cerebellum in rats. In the cerebellar vermis the parallel fibers (PF) to Purkinje cell (PC) synapse is potentiated one day following fear learning. Pretraining BLA inactivation impaired...
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PMID: 21304962
PDF is available here.
Abstract
We defined physiological responses in macaque somatosensory cortex during serial, matched, detection and discrimination tasks. Nonselective increases in neural responsiveness were observed during detection learning. Suppression of responses to task distractors was observed during discrimination lear...
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PMID: 21297962
PDF is available here.
Abstract
We argue that there is a need to move away from this class of model and find the principles that govern gaze allocation in a broader range of settings. We outline the major limitations of salience-based selection schemes and highlight what we have learned from studies of gaze allocation in natural v...
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PMID: 21622729
PDF is available here.
Abstract
Parkinson's disease, which affects the basal ganglia, is known to lead to various impairments of motor control. Since the basal ganglia have also been shown to be involved in learning processes, motor learning has frequently been investigated in this group of patients. However, resul...
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PMID: 21760898
PDF is available here.
Abstract
A decision is a commitment of resources under conditions of risk in expectation of the best future outcome. The smart decision is always the strategy with the best overall expected value-the best combination of facts and values. Some of the special circumstances involved in decision making are discus...
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PMID: 21739870
PDF is available here.
Abstract
We developed a MC assessment instrument to assess DMCCC of clinical psychology graduate students compared with MC-experienced psychologists. In addition, we assessed for differences between the endorsement of MC-appropriate strategies and actual use of these strategies in clinical practice, both by...
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PMID: 21341892
PDF is available here.
Abstract
Powered wheelchairs are essential for many individuals who have mobility impairments. Nevertheless, if operated improperly, the powered wheelchair poses dangers to both the user and to those in its vicinity. Thus, operating a powered wheelchair with some degree of proficiency is important for safety,...
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PMID: 21609435
PDF is available here.
Abstract
Behavior such as depression of a lever or perception of a stimulus may be strengthened by consequent behaviorally significant events (BSEs), such as reinforcers. This is the Law of Effect. As time passes since its emission, the ability for the behavior to be reinforced decreases. This is trace decay....
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PMID: 21215304
PDF is available here.
Abstract
While providers, consumers, and administrators recognize the need to attract and retain nurses, recruiting, transitioning, and retaining new graduate nurses (NGRNs) remains problematic. The first 3-12 months of NGRN employment is a perilous and stressful time, with experiences during the transition p...
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PMID: 21667675
PDF is available here.
Abstract
Research indicates that augmentative and alternative communication (AAC) approaches can be used effectively by patients and their caregivers to improve communication skills. This article highlights strategies and tools for re-establishing communication competence by considering the complexity and div...
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PMID: 21447459
PDF is available here.
Abstract
Real case studies of how nurses are improving patient care are now available to inspire others.
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PMID: 21736023
PDF is available here.
Abstract
We show that gossip does not influence only how a face is evaluated--it affects whether a face is seen in the first place. In two experiments, neutral faces were paired with negative, positive, or neutral gossip and were then presented alone in a binocular rivalry paradigm (faces were presented to o...
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PMID: 21596956
PDF is available here.
Abstract
We investigated face recognition as an ability that may mature late relative to other abilities. Using data from over 60,000 participants, we traced the ability to learn new faces from pre-adolescence through middle age. In three separate experiments, we show that face learning ability improves unti...
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PMID: 21130422
PDF is available here.
Abstract
We hypothesized that θ-rhythm modulation would also occur at subhypnotic but amnestic concentrations. Therefore, we examined the effect of three inhaled agents on properties of the θ rhythm considered critical for the formation of hippocampus-dependent memories.
We studied the effects of halothane...
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PMID: 21042201
PDF is available here.
Abstract
Self-directed learning (SDL) skills are essential for the formation and ongoing competence of today's physicians who work in the context of expanding scientific knowledge and changing health care systems. In 2007-2008, the authors developed a program to promote SDL in the Brown University Family Med...
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PMID: 20978433
PDF is available here.
Abstract
These results suggest that Gen confers protection against Ovx-induced neurodegeneration by attenuating oxidative stress, lipid peroxidation and the mitochondria-mediated apoptotic pathway in a region- and dose-dependent manner....
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PMID: 20579403
PDF is available here.
Abstract
We hypothesize that wagering and other subjective measures of awareness reflect metacognitive capacities subtended by self-developed metarepresentations that inform an agent about its own internal states. To support this idea, we present three simulations in which neural networks learn to wager on t...
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PMID: 20825936
PDF is available here.
Abstract
Quality improvement (QI) in health care involves activities ranging from enhancing personal practice to reforming the larger health care system. The Accreditation Council for Graduate Medical Education recognizes this broad definition of QI in its requirement that physicians-in-training demonstrate...
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PMID: 20881823
PDF is available here.
Abstract
Since team-based learning (TBL) was introduced as a medical education strategy in 2001, few studies have explored its impact on learning outcomes, particularly as measured by performance on examinations. Educators considering implementing TBL need evidence of its effectiveness. This study was conduc...
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PMID: 20881827
PDF is available here.
Abstract
This paper provides information about the efficacy of a tutorial training program intended to enhance elementary fifth graders' study processes and foster their deep approaches to learning. The program "Testas's (mis)adventures" consists of a set of books in which Testas, a typical student, reveals...
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PMID: 21044520
PDF is available here.
Abstract
The present work attempts to determine whether procedural learning of a semantic categorisation task is influenced by the type of semantic category of the stimuli (biological and non-biological elements). It is also an attempt to determine the effect of the stimulus presentation modality on the cate...
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PMID: 21044507
PDF is available here.
Abstract
We bear in mind that latent inhibition has been used repeatedly as an instrument to analyze the course of attentional processes in normal and pathological populations....
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PMID: 21044502
PDF is available here.
Abstract
Two experiments were used to assess the efficacy of the keyword mnemonic method in adults. In Experiment 1, immediate and delayed recall (at a one-day interval) were assessed by comparing the results obtained by a group of adults using the keyword mnemonic method in contrast to a group using the rep...
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PMID: 21044509
PDF is available here.
Abstract
In Higher Education, performance and Teaching-Learning (T-L) contexts are highly current concerns. Based on the DEDEPRO model, interdependence can be established between instructional contexts and levels of performance as they relate to the T-L process. Partitipants were 2020 pupils from two Spanish...
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PMID: 21044517
PDF is available here.
Abstract
We conclude that Broca's area is specifically involved in rule-based knowledge, and here, in an improved ability to detect syntactic violations. The results cannot be explained by better tDCS-induced working memory performance during the acquisition phase. This is the first study that demonstrates t...
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PMID: 19925194
PDF is available here.
Abstract
We propose the mediator effectiveness hypothesis, which states that more-effective mediators (that is, information linking cues to targets) are generated during practice involving tests with restudy versus during restudy only. Effective mediators must be retrievable at time of test and must elicit t...
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PMID: 20947756
PDF is available here.
Abstract
We describe the first four phases of a curriculum reform covering the three clinical years of medical school at Aarhus University. The reform intends to ease students' transition from medical school to the foundation year, increase focus on communication, create more coherence between subjects, incr...
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PMID: 21040661
PDF is available here.
Abstract
The aim of this paper is to introduce the reader to personal construct psychology as a theory to help understand the process of change in facilitative and mentoring relationships.
Continuing professional development is critical if practitioners are to keep up to date with new ideas, techniques, and...
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PMID: 20887672
PDF is available here.
Julius Cuong Pham,
Sebastiana Gianci,
James Battles,
Paula Beard,
John R Clarke,
Hilary Coates,
Liam Donaldson,
Noel Eldridge,
Martin Fletcher,
Christine A Goeschel,
Eugenie Heitmiller,
Jörgen Hensen,
Edward Kelley,
Jerod Loeb,
William Runciman,
Susan Sheridan,
Albert W Wu and
Peter J Pronovost
Abstract
BACKGROUND: Incident-reporting systems (IRS) collect snapshots of hazards, mistakes and system failures occurring in healthcare. These data repositories are a cornerstone of patient safety improvement. Compared with systems in other high-risk industries, healthcare IRS are fragmented and isolated, a...
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PMID: 20977995
PDF is available here.
Abstract
While self-assessments may not validly indicate ability, it is still critical to determine how students perceive their ability because their opinions drive their learning goals....
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PMID: 20881690
PDF is available here.