Abstract
Three-dimensional ultrasonographic technologies may improve the pre-natal diagnosis of main stem BA....
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PMID: 20375382
PDF is available here.
Abstract
In the past decade, rapid technical developments and advancements of multidetector computed tomography (MDCT) have revolutionized the preoperative imaging evaluation of thoracic vascular and tracheobronchial anomalies and abnormalities in infants and children. Multidetector computed tomography enabl...
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PMID: 20385293
PDF is available here.
Abstract
We describe an infant of 8 months who presented with left ventricular dilation due to an extensive intralobar sequestration of the right lung. The pulmonary sequestration was associated with a patent arterial duct and a right aortic arch. Percutaneous closure of the anomalous aberrant artery feeding...
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PMID: 19788781
PDF is available here.
Abstract
Safe oral alimentation early in the postoperative period is possible with a rigorous multidisciplinary approach. To minimize complications, postoperative oral feeding should be initiated in conjunction with a speech pathologist....
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PMID: 19358199
PDF is available here.
Abstract
The DRS provides a safe effective system for imaging the equine URT during ridden exercise at speed. The abnormalities of the URT identified were similar to those observed during treadmill endoscopy studies reported in the literature. The effect of URT abnormalities on ridden speed requires further...
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PMID: 19562896
PDF is available here.
Abstract
This study validates the safety and the reliability of the DRS for imaging the equine URT during natural exercising conditions. POTENTIAL RELEVANCE: Most common causes of DO-URT can be diagnosed easily during any type of performance without a treadmill and the DRS offers a great potential for furthe...
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PMID: 19562895
PDF is available here.
Abstract
Forty-eight horses that underwent thermal cautery and 30 conservatively treated controls were included. Pretreatment earnings significantly decreased in the race immediately prior to diagnosis. A high proportion of previously raced horses returned to racing after both treatments (90-96%). Intrahorse...
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PMID: 19301584
PDF is available here.
Abstract
Twenty-two patients (78.6%) survived. Of these, 15 required NO (NO-s), and seven did not (non-NO-s). All six patients that died required NO (NO-d). RPA in the NO-d group was significantly smaller than in the NO-s or non-NO-s groups on day 0 (2.90 +/- 0.41 vs. 3.40 +/- 0.49 or 4.01 +/- 0.43; P < 0.01...
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PMID: 18985361
PDF is available here.
Abstract
Dynamic collapse of the upper respiratory tract (URT) is a common cause of poor performance in horses. These conditions occur predominantly during strenuous exercise when the URT is unable to maintain dilation in the face of high inspiratory pressures. In most cases, these disorders cannot be accura...
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PMID: 19165944
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Abstract
We report the typical ventilation abnormalities, collateral ventilation and air trapping in the affected lung segment demonstrated on xenon ventilation CT in a child with bronchial atresia....
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PMID: 18542942
PDF is available here.
Abstract
Head position affects the relationship between the hyoid apparatus and larynx preoperatively, with greatest distance occurring when the head is extended. In a flexed position, it is not possible to ascertain whether laryngeal position has changed postoperatively. CLINICAL RELEVANCE: A standardized h...
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PMID: 19134081
PDF is available here.
Abstract
Esophageal atresia, congenital diaphragmatic hernia, bronchopulmonary malformations and cystic lung diseases are the common neonatal thoracic surgical lesions encountered in practice. The availability of antenatal ultrasonography has lead to these lesions being detected before birth. Antenatal diagn...
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PMID: 19011806
PDF is available here.
Abstract
We describe a case of "topsy-turvy heart" that necessitated simultaneous left tracheobronchial repair, aortic arch reconstruction, and bronchial stenting in an 11-month-old girl. This case highlights the significant therapeutic dilemmas clinicians are faced with when dealing with conditions having a...
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PMID: 18573438
PDF is available here.
Abstract
We discuss the appropriate radiologic investigations and the necessity for surgical intervention. The possible embryogenesis is hypothesized....
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PMID: 18639672
PDF is available here.
Abstract
Thermocautery of the soft palate alone may not be the most efficacious treatment of DDSP. POTENTIAL RELEVANCE: Production of a reliable measure of racehorse performance may be possible....
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PMID: 18490236
PDF is available here.
Abstract
Horses undergoing a LTFP are as likely to race post operatively as matched controls. The procedure restores race earnings to preoperative baseline levels and to those of matched controls. POTENTIAL RELEVANCE: This study provides strong evidence supporting the use of the LTFP in racehorses. Further w...
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PMID: 18490235
PDF is available here.
Abstract
One case died from severe low cardiac output after operation. Two cases were complicated postoperatively with II degree atrial ventricular block and one with pulmonary hypertensive crisis, and all were cured after treatment. And the other patients recovered after surgery. Follow-up showed that the q...
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PMID: 18754443
PDF is available here.
Abstract
We report two cases of fetuses who presented pathological examination of the lung on the ultrasonography, at 22 weeks of gestation, suspect of prenatal bronchial atresia diagnosis. We analysed this malformation through a literature review in order to discuss differential diagnosis to be evoked, as w...
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PMID: 18417406
PDF is available here.
Abstract
Our results demonstrate that prenatal treatment with retinoic acid stimulates alveologenesis in hypoplastic lungs in CDH....
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PMID: 18358289
PDF is available here.
Abstract
Lung resection is safe and well tolerated in infancy. Surgery should be scheduled before the development of symptoms but likely after 3 months of age to improve the chances of postoperative extubation. The use of regional anesthesia may facilitate this....
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PMID: 18358290
PDF is available here.
Abstract
Our results demonstrate that prenatal treatment with RA accelerates AEC-I proliferation in the hypoplastic lung in CDH....
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PMID: 18280292
PDF is available here.
Abstract
We describe an unusual appearance seen on a ventilation-perfusion (V/Q) scan in a woman with pulmonary hypertension. Although the pulmonary hypertension was not caused by pulmonary emboli, the V/Q scan suggested several cardiac anomalies which may lead to pulmonary hypertension. Most of the cardiac...
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PMID: 19173188
PDF is available here.
Abstract
We conclude that Sandifer's syndrome is a clinical manifestation of another vagal reflex that could be termed a "vagocervical" or "esophagocervical" reflex, based on the neuroanatomical hypotheses elaborated in this paper....
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PMID: 18031943
PDF is available here.
Abstract
Almost 90% of the subjects showed 1 of the 7 types of septal deformity. There were no statistically significant differences in the incidence of their appearance among particular geographic regions. Type 3 was the most frequent type. Straight septum was twice as frequent in females than in males....
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PMID: 18314016
PDF is available here.
Abstract
We hypothesized that R-CDH and L-CDH are phenotypically and pathogenically distinct, and that the frequency of associated anomalies would differ among patients with R-CDH compared to patients with L-CDH. Using population-based data from ongoing studies in the California Birth Defects Monitoring Prog...
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PMID: 18008313
PDF is available here.
Abstract
The algorithms utilised in the diagnosis of chronic cough advocate sequential investigations and treatment trials for asthma-like syndromes, post-nasal drip and gastro-oesophageal reflux disease; however, the role of bronchoscopy is unclear. In the present authors' specialist clinic (North West Lung...
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PMID: 17928312
PDF is available here.
Abstract
We studied epidermal growth factor receptor (EGFR) and K-RAS oncogene, 2 biological markers closely associated with tumorigenesis and altered in many types of tumors, including lung carcinomas. For this purpose, we used immunohistochemistry and gene sequencing in paraffin-embedded tissue. Our result...
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PMID: 17714760
PDF is available here.
Abstract
Pulmonary hypoplasia seen in newborn rabbits after experimentally induced diaphragmatic hernia is less severe in those rabbits with concurrently made gastroschisis or tracheal ligation. From the histologic viewpoint, the effects of gastroschisis and tracheal ligation on pulmonary hypoplasia in diaph...
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PMID: 18082702
PDF is available here.
Abstract
We are reporting a case of supernumerary nostril in association with complete unilateral cleft lip without cleft palate, which happens to be the first case of its kind to be reported. Most supernumerary nostrils are situated superior to the normal nostrils and very few of them are situated at the sa...
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PMID: 18177189
PDF is available here.
Abstract
Congenital bronchial stenosis is a very uncommon condition in children. A full-term neonate showed severe respiratory distress soon after birth. Bronchoscopy and spiral computed tomography with multiplanar reconstruction disclosed a short stenosis of the left main bronchus, next to the carina, and a...
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PMID: 18022418
PDF is available here.
Abstract
I take the opportunity both to review our recent findings on lung growth and prenatal ASM, and also to discuss mechanisms by which ASM contractility can regulate growth. Finally, I will introduce some novel ideas for exploration: ASM contractility could help to schedule parturition (pulmonary partur...
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PMID: 17619196
PDF is available here.
Abstract
A girl with polydactyly has had respiratory tract problems, including atelectasis, since birth. She has a high arched palate, a tongue hamartoma and dysmorphic face. Electron microscopy of nasal and bronchial brush biopsies repeatedly revealed centriole/basal body disarray and extreme sparseness of...
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PMID: 17577347
PDF is available here.
Abstract
Long-segment tracheal stenosis in infants and small children is difficult to manage and can be life-threatening. A retrospective review of 12 patients who underwent surgery for congenital tracheal stenosis between 1996 and 2004 was conducted. The patients' median age was 3.6 months. All patients had...
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PMID: 17596659
PDF is available here.
Abstract
Today, congenital thoracic malformations (CTMs), which comprise a spectrum of anomalies rather than separate entities, are frequently detected on routine antenatal ultrasound. However, with similar appearances of different congenital lung and nonpulmonary lesions, a definitive diagnosis cannot usual...
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PMID: 17562505
PDF is available here.
Abstract
We describe a new case of pneumosinus dilatans in a 21-year-old woman. She required no treatment....
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PMID: 17580810
PDF is available here.
Abstract
Tracheal duplication is a very rare infant congenital airway anomaly. We report a bronchogenic cyst communicating with a tracheal duplication. This is the first reported case of pathologically confirmed duplication of trachea communicating with a bronchogenic cyst.
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PMID: 17336200
PDF is available here.
Abstract
Congenital malformations of the lung are rare and vary widely in their presentation and severity. The most common manifestation of the congenital cystic disease of the lung at newborn and early infancy is respiratory distress. Later on in life, cysts usually lose this compressive character and may r...
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PMID: 17337833
PDF is available here.
Abstract
Oculoauriculofrontonasal syndrome was the subset of patients with oculo-auriculo-vertebral spectrum and frontonasal malformation. Radiographic evidence of tracheal duplication was documented in a male infant with oculoauriculofrontonasal syndrome. Although previously unreported in oculoauriculofront...
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PMID: 17159514
PDF is available here.
Abstract
We report a 9-month-old female infant presenting, on the 15th day of life, left tibial agenesis with ectrodactyly, right talipes equinovarus, syndactyly of the second and the third toes of the right foot, an incomplete split right foot, left fibular hypoplasia, bronchial stenosis/hypoplasia, and coa...
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PMID: 17159515
PDF is available here.
Abstract
We report a case of anomalous right upper lobe venous drainage resulting in two right upper lobe veins draining into the azygous vein and into the confluence between superior vena cava and azygous vein, respectively. Preoperative identification of such an aberrant venous drainage is useful for avoid...
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PMID: 17126150
PDF is available here.
Abstract
We hypothesize that ASM hyperreactivity and its sequelae are based on an early developmental lesion of ASM activity in hypoplastic lung. Sprague-Dawley rats were fed 100 mg nitrofen on Day 9.5 of pregnancy to induce lung hypoplasia in offspring (controls had vehicle alone). Normal and hypoplastic lu...
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PMID: 16728706
PDF is available here.
Abstract
We report 2 cases of prenatally diagnosed congenital lobar emphysema caused by bronchial atresia at the left upper lobar bronchus. Three-dimensional computed tomography bronchoscopy was effective to demonstrate accurate anatomical changes of the bronchus....
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PMID: 17101340
PDF is available here.
Abstract
We hypothesized ASM dysfunction emerges in tandem with, and may contribute toward, the primordial lung hypoplasia that precedes experimental CDH. Spatial origin and frequency of ASM peristaltic waves were measured in normal and hypoplastic rat lungs cultured from day 13.5 of gestation (lung hypoplas...
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PMID: 16603591
PDF is available here.
Abstract
A 36-year-old woman presented with left chest pain and frequent symptoms of upper respiratory infection. Chest roentgenograms revealed a left pneumothorax and apical bulla, and hyperlucency in the left pulmonary field. She was diagnosed with congenital bronchial atresia associated with a left sponta...
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PMID: 16996962
PDF is available here.
Abstract
Helical and multidetector CT with 2D and 3D reconstructions clearly delineated the aberrant tracheobronchial and esophageal anatomy in each infant. Minimum intensity projection reformatted CT images were particularly helpful. One infant each had type I and type II tracheal agenesis. Two infants had...
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PMID: 16788813
PDF is available here.
Abstract
Endoscopy of the resting horse showed low sensitivity (0.15) in the diagnosis of dorsal displacement of the soft palate (DDSP) and palatal instability (PI). When endoscopy and reported noises were taken together there was still a 35% misdiagnosis rate. Although there was significant association betw...
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PMID: 16986599
PDF is available here.
Abstract
Dynamic collapse within the nasopharynx or larynx was confirmed in 471 of the 600 horses. Dorsal displacement of the soft palate (DDSP; 50%) and palatal instability (33%) were the disorders most frequently identified. It was concluded that deglutition is not a significant event in the triggering of...
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PMID: 16986598
PDF is available here.
Abstract
There are limited data on the correlations between arterial blood gas (ABG) values, tracheal wash (TW) cytology and upper respiratory tract (URT) abnormalities.
To identify horses with abnormal exercising ABG, and compare the proportions of horses with abnormal ABG an...
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PMID: 17402477
PDF is available here.
Abstract
The effects of nitrofen in fetal rat lungs are reversed in part by antioxidant vitamins by upregulating the expression of TTF-1, HNF-3beta, and SP-B. This approach could help to develop transplacental prenatal interventions for CDH....
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PMID: 16863852
PDF is available here.
Abstract
Epiglottis anomaly associated with Pierre Robin sequence (PRS) is a rare occurrence. To the knowledge of the authors, this is the first reported case of epiglottic anomaly associated with PRS. Doctors should remain aware of this atypical presentation in a PRS patient, and the presented case highligh...
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PMID: 16545943
PDF is available here.
Abstract
Bronchopulmonary foregut malformations are uncommon anomalies, and their association with diaphragmatic eventration is rare. This report presents 2 cases with this association. Embryologically, a simultaneous disturbance in the development of pulmonary vessels and developing esophagotracheal septum...
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PMID: 16818075
PDF is available here.
Abstract
High quality measurements of respiratory sounds during over-ground exercise can be made relatively easily. POTENTIAL RELEVANCE: The system enables measurement of respiratory sounds outside a laboratory environment creating new opportunities for scientific research and clinical assessment. The study...
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PMID: 16866198
PDF is available here.
Abstract
Epidural analgesia in children is highly effective and safe; however, it has not enjoyed great popularity in surgery that requires cardiopulmonary bypass. A major concern is the possibility of damage to blood vessels with the epidural needle or catheter and epidural hematoma formation. There seems t...
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PMID: 16719889
PDF is available here.