Abstract
The presence of a cytokine storm is recognized as a condition possibly involved in the mechanism for the onset, aggravation and progression of acute encephalitis/encephalopathy. Plasma exchange and slow hemodiafiltration have been used as the means of blood purification to deal with acute encephaliti...
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PMID: 21400852
PDF is available here.
Abstract
We report the case of a 55-year-old patient with a large central Palacos embolism of the right pulmonary artery after corporectomy of the lumbar vertebrae 3 and 4 and reconstruction using autologous pelvic bone. The large Palacos embolism was removed successfully from the right pulmonary artery with...
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PMID: 20922632
PDF is available here.
Abstract
The transient systemic low perfusion that occurs during cardiovascular surgery leads to oxidative stress and the production of free radicals. A systemic increase of various markers of oxidative stress has been shown to occur during cardiopulmonary bypass (CPB). However, these markers have not been a...
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PMID: 20975766
PDF is available here.
Abstract
We reviewed the current strategies to rescue patients with severe hypoxemia. Included in these strategies are high-frequency oscillatory ventilation, airway pressure release ventilation, inhaled vasodilators, and the use of extracorporeal life support. All of these strategies are targeted at improvi...
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PMID: 20624836
PDF is available here.
Abstract
We connected our extracorporeal membrane oxygenation (ECMO) circuit to the patient. To minimize reperfusion injury, immediate cooling, arterial/venous shunting, minimal calcium, and hemodilution strategies were used. Once paCO2/pvCO2 gradients were minimized, we instituted sweep gas and gradually in...
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PMID: 21114229
PDF is available here.
Abstract
A recently completed study quantified the percent of fentanyl or morphine sulfate lost to uncoated polyvinylchloride (PVC) tubing or to one of two hollow fiber oxygenators within the extracorporeal life support (ECLS) circuit. The results demonstrated the majority of drug loss was due to adsorption...
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PMID: 21114222
PDF is available here.
Abstract
We established a porcine model of hypoxemia/acidemia without an underlying disease and further challenged the situation with an extracorporeal circuit (ECC).
Hypoxemia/acidemia were induced (3.5 h) and maintained (3 h) in anesthetized pigs (40 kg) by a stepwise reduction in oxygenation, infusion of...
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PMID: 20872349
PDF is available here.
Abstract
We describe an original modified percutaneous cannulation technique developed in our Department and we report our clinical experience and complications observed.
A Seldinger technique utilizing 3 guidewires with passage of a dilator over each guidewire was used. Two concentric pursestring sutures, p...
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PMID: 20872350
PDF is available here.
Abstract
During the last decade, minimized extracorporeal circulation (MECC) systems have shown beneficial effects to the patients over the conventional cardiopulmonary bypass (CECC) circuits. This is a prospective randomized study of 99 patients who underwent coronary artery bypass grafting (CABG) surgery,...
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PMID: 20515982
PDF is available here.
Abstract
We diagnosed right renal cancer (stage III), and he underwent radical nephrectomy and resection of tumor thrombus with extracorporeal circulation. Operative time was 9 hours. Time for extracorporeal circulation was 119 minutes, and it took 60 minutes for intraoperative balloon occlusion of descendin...
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PMID: 20715501
PDF is available here.
Abstract
We propose the term non-routine events (NREs) instead of accidents, and provide a working definition and reporting threshold for such. This paper describes the program which we developed to track perfusion NREs within the Cardiovascular Program at Children's Hospital, Boston. NREs are categorized by...
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PMID: 20648903
PDF is available here.
Abstract
Although serious accidents during extracorporeal circulation are infrequent, potential adverse events with both equipment and operation do still occur and require immediate and well-coordinated responses. Hence, perfusionists need to be well trained in both standard and emergency procedures, and thi...
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PMID: 20648899
PDF is available here.
Abstract
The TEG (kaolin) sample was not interpretable due to the heparin effect in 89 (52%) samples. There was a weak correlation between TEG (heparinase) variables and APTT, and between TEG and ACT with a stronger correlation between TEG (Maximum amplitude) and platelet count. CONCLUSION: TEG monitoring sh...
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PMID: 19674773
PDF is available here.
Abstract
Patients with end-stage heart failure have poor quality of life and a poor prognosis. These patients are usually burdened by symptoms at rest, the need for frequent hospital admissions, complex pharmacological therapies and a 1-year mortality rate of about 50%. Therapeutic options are scarce and not...
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PMID: 20550058
PDF is available here.
Abstract
While several clinical trials have suggested that leukocytapheresis (LCAP) by filtration can benefit patients with active ulcerative colitis, the mechanisms underlying these benefits are largely unknown. The aim of this study was to address the mechanisms that may underlie the therap...
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PMID: 19259814
PDF is available here.
Abstract
We addressed this issue in this study. The hypothesis was to find a higher MAP during coronary bypass grafting surgery in patients treated with MECC systems. We performed a prospective, controlled, randomized trial with 40 patients either assigned to MECC (n = 18) or CCPB (n = 22) undergoing coronar...
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PMID: 20437789
PDF is available here.
Abstract
Extracorporeal affinity adsorption treatment is a method that safely and efficiently reduces myelotoxicity associated with RIT. Extracorporeal affinity adsorption treatment allows increased administered activity without increased toxicity, with the aim of increasing the absorbed dose to the tumor. H...
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PMID: 20127949
PDF is available here.
Abstract
Extracorporeal affinity adsorption treatment can be used to reduce the toxicity associated with administration of BR96-MMAF conjugates, making it possible to increase the amount of conjugates administered. The combined treatment will be further optimized in future studies.
(c) 2010 American Cancer S...
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PMID: 20127954
PDF is available here.
Abstract
The durability of extracorporeal devices for some weeks was described in many institutional and case reports. The change in technology seems to open a new era of possibilities. Use of this new technology not only in bridge to transplant but also as a bridge to recovery in acute respiratory distress...
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PMID: 19952734
PDF is available here.
R Vicente,
A Pajares,
J L Vicente,
R Aparicio,
J M Loro,
I Moreno,
A Soria,
A López,
J Porta,
C de la Fuente,
P Herrera,
A Tur,
F Osseyran,
A Guillén,
F Martí,
J Llagunes,
E Mateo,
F Aguar,
J J Peña,
J I Marqués,
A Ripoll,
C Reina,
P Ferrandis,
V Muedra,
E Llopis,
M Cantó and
C García
Abstract
The highest mortality rate among cardiac surgery patients in postoperative critical care units in hospitals in the Community of Valencia in 2007 was in patients who underwent coronary revascularization. The most prevalent preoperative risk factor was hypertension. Cardiogenic shock and distributive...
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PMID: 20336998
PDF is available here.
Abstract
We present our experience with extracorporeal immunoglobulin (Ig) elimination by immunoadsorption (adsorbers with human Ig antibodies). Acetylcholine receptor antibodies (AChRAs) were measured during long-term monitoring (4.7 +/- 2.9 years; range 1.1-8.0). A total of 474 samples (232 pairs) were ana...
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PMID: 20300435
PDF is available here.
Abstract
We were able to significantly reduce concentrations of the proinflammatory cytokine tumor necrosis factor (TNF)-alpha from initially very high levels. Passage of blood over nonheparinized beads did not affect the TNF levels. Meanwhile, concentrations of the regulated on activation, normal T-cells ex...
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PMID: 20071911
PDF is available here.
Abstract
The present study was undertaken to investigate the structure of hospital mortality associated with surgical treatment of 166 patients presenting with thoracoabdominal aortic aneurysms. According to the findings obtained, haemorrhagic, renal, and pulmonary complications turned out to predominate in...
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PMID: 20635724
PDF is available here.
Abstract
We summarize our experience with a computational, multiscale investigation of this device's hydrodynamic functionality. 3D computational fluid dynamics models were developed for the upper-scale studies. The flow behavior in the sorbent material was either modeled as a homogeneous Darcy's flow (macro...
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PMID: 20519899
PDF is available here.
Abstract
We performed a prospective study to assess the prevalence of EA in critically ill patients and its association with organ dysfunction and outcome, as well as in septic shock. EA (EAA(TM)) was measured within 24 h from onset of refractory septic shock in an intensive care unit. Our study demonstrated...
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PMID: 20519904
PDF is available here.
Abstract
All plasma collected upon inclusions, as well as plasma from conventionally treated patients at 72 h, significantly increased apoptosis, while plasma collected from patients following PMX-B treatment induced significantly less apoptosis than time 0 or conventionally treated controls. This decreased...
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PMID: 20519900
PDF is available here.
Abstract
The different methods for anticoagulation of the extracorporeal circuit for renal replacement therapy (RRT) vary in safety profile, bleeding being the most important side effect. Avoiding severe bleeding is a key aim of RRT prescription. The present paper is a clinical review comparing regional anti...
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PMID: 20427976
PDF is available here.
Abstract
We focused on the characterization of the interactions occurring in the formation of the PMB-endotoxin complex at the molecular level. In particular, the molecular mechanics approach was used to evaluate the interaction energy and eventually the interaction force between the two molecules. PMB was f...
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PMID: 20519898
PDF is available here.
Abstract
The use of Di-2-ethylhexyl phthalate (DEHP) plasticised polyvinyl chloride (DEHPPPVC) in medical devices persists despite evidence suggesting that DEHP migration can be harmful. Researchers have shown that a simple surface sulfonation process can retard the migration of DEHP, which m...
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PMID: 20159936
PDF is available here.
Abstract
We describe the detection of postoperative neurologic complications by means of monitoring cerebral oximetry during cardiac surgery. A 54-year-old man underwent emergency surgery for aortic dissection, type A. Cerebral oximetry was monitored by near-infrared spectroscopy. At the start of total cardi...
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PMID: 20645490
PDF is available here.
Abstract
Preoperatively there where 3 patients in each of the study groups 7.5% (6/80) with severe neurological deficit. Postoperative severe neurological complications (coma, hemiparesis, hemiplegia, paraparesis or paraplegia) was recognized in 7.5% (6/80) of patients. Control group with retrograde perfusio...
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PMID: 20422817
PDF is available here.
Abstract
We present associated a case of a 65-year old patient with non-fatal ascending aortic dissection after coronary artery bypass grafting using extracorporeal circulation....
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PMID: 20131198
PDF is available here.
Abstract
The groups were similar regarding demographic and intraoperative variables, except for a greater hemodilution in the Aprotinin Group. The drug had no benefit regarding time of mechanical pulmonary ventilation, permanence in the pediatric postoperative intensive care unit (ICU) and length of hospital...
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PMID: 20305926
PDF is available here.
Abstract
This study was designed to analyze flow pattern, velocity, and strain on the aortic wall of a glass aortic arch aneurysm model during the extracorporeal circulation, and to elucidate the characteristics of flow pattern in three different aortic cannulae. Different patterns of large v...
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PMID: 19995359
PDF is available here.
Abstract
Patient characteristics and operative parameters were equal for patients in both groups. With autologous priming, a mean volume of 614.8 +/- 138.8 ml of priming solution was replaced with autologous blood. This allowed a significantly higher haematocrit value during cardiopulmonary bypass (P < 0.05)...
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PMID: 19770662
PDF is available here.
Abstract
Extracorporeal life support is becoming increasingly popular with the miniaturization of the devices necessary for cardiac and pulmonary support. In the present report, the current systems, indications for placement and limitations are reviewed.
Copyright Georg Thieme Verlag KG Stuttgart . New York....
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PMID: 20013616
PDF is available here.
Abstract
: The 2002 guidelines were widely disseminated, translated into Spanish and Portuguese, and incorporated into Society of Critical Care Medicine and AHA sanctioned recommendations. Centers that implemented the 2002 guidelines reported best practice outcomes (hospital mortality 1%-3% in previously heal...
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PMID: 19050601
PDF is available here.
Abstract
The time of CPB and aortic occlusion were 40 to 290 minutes (107 +/- 52) and 27 to 195 min (70 +/- 36 min) respectively. The endotracheal intubation durations were 5 to 21 hours (14 +/- 15) and ICU duration 11 to 183 hours (45 +/- 34). Comparing with the pre-operative echocardiographic parameters, t...
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PMID: 20137602
PDF is available here.
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
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PMID: 19817727
PDF is available here.
Abstract
A study aimed to compare the efficiency of the ozone transfer of four hydrophilic dialysis filters, and one hydrophobic gas-exchange device (GED) has been performed. Obviously, the former should be specifically used only for dialysis. Unfortunately, some clinicians incautiously use t...
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PMID: 19817737
PDF is available here.
Abstract
Today, worldwide approximately 1.5 million uremic patients owe their lives to hemodialysis. This figure will increase further by a growth rate of 6% annually reflecting a necessary increasing high interest in innovative technologies as well as in individualized therapies in this area. The main focus...
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PMID: 19807288
PDF is available here.
Abstract
The experience of patients, suffering mediastinal compression syndrome, caused by vena cava superior syndrome treatment, is presented. The types of vena cava superior affection are delineated, methods of operative treatment of patients in the clinic are depicted.
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PMID: 20458944
PDF is available here.
Abstract
The investigated bedside test is clinically feasible, simple, and can be completed within 30 minutes. Further studies are encouraged to compare this method with other tests in a larger, stratified cardiac surgery population....
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PMID: 19721398
PDF is available here.
Abstract
Lung transplantation is associated with a significant reduction in pulmonary artery pressures immediately after graft implantation. The persistence of pulmonary hypertension in the early postoperative period suggests temporal allograft dysfunction and affects the post-operative outcome....
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PMID: 19838955
PDF is available here.
Abstract
Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around...
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PMID: 19340688
PDF is available here.
Abstract
Calcium channel blockers continue to be used for the management of a wide variety of adult and pediatric conditions including hypertension, angina pectoris, atrial arrhythmias, Raynaud phenomenon, and migraine headaches. With increased use comes increased potential for misuse and abuse. This article...
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PMID: 19687715
PDF is available here.
Abstract
Fast track in cardiac surgery is not well defined. In the past early or immediate extubation was used as a marker. After cardiac surgery this parameter is not sufficient. In addition to cardiorespiratory stability, circulatory and haemostatic homeostasis are also required. Therefore the current Fast...
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PMID: 19585089
PDF is available here.
Abstract
We present the case of a patient with coarctation of the abdominal aorta associated with stenosis of the celiac trunk, the superior mesenteric and the right renal arteries. Distal aortic perfusion by extracorporeal circulation and selective right renal perfusion techniques were used during the opera...
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PMID: 18948875
PDF is available here.
Abstract
We report anesthetic management using veno-veno bypass (V-V bypass) for emergent tracheostomy in a patient with acute epiglottitis. A 72-year-old woman complained of dyspnea due to acute epiglottitis, and emergent tracheostomy was planned for her. Since physical and optical fiberscopic examinations...
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PMID: 19702219
PDF is available here.
Abstract
Extracorporeal cardiopulmonary support (ECS) of donors after cardiac death (DCD) has been shown to improve abdominal organs for transplantation. This study assesses whether pulmonary congestion occurs during ECS with the heart arrested and describes an in vivo method to assess if lungs are suitable...
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PMID: 19506464
PDF is available here.
Abstract
Since the advent of extracorporeal circulation in 1954, its technique has developed rapidly owing to the progress of technology. Although it facilitated better outcome of cardiac surgery, lack of knowledge and malpractice of extracorporeal circulation may lead to serious complications. This article...
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PMID: 20715688
PDF is available here.