Abstract
Patients' motives for implant BR were primarily related to surgical issues, whereas women who chose DIEP-flap BR especially focussed on regaining a breast that resembles their own lost breast as well as possible. Clinical variables (such as therapeutic or prophylactic mastectomy, breast irradiation,...
|
PMID: 21514261
PDF is available here.
Abstract
The purpose of this study was to investigate the surgical management of radiation-associated cutaneous breast angiosarcoma with an emphasis on surgical margins and choice of reconstruction. Nine cases of angiosarcoma were identified in patients earlier treated with radiotherapy for b...
|
PMID: 21377947
PDF is available here.
Abstract
The purpose of this study is to assess the impact of adjuvant therapy on survival in males with non-metastatic breast cancer.
A retrospective analysis of male breast cancers treated between 1990 and 2003 was performed. Age, estrogen and progesterone receptor (ER/PgR)...
|
PMID: 21421521
PDF is available here.
Abstract
To determine the incidence of malignancy (invasive carcinoma or DCIS) in patients diagnosed with lobular neoplasia (B3) on core needle biopsy (CNB) of breast lesions by reviewing the published literature.
Medline, Embase, OVID-database and reference lists were searche...
|
PMID: 21306860
PDF is available here.
Abstract
Little is known about the use of breast MRI as a diagnostic or surveillance tool in patients after bilateral mastectomy. The objective of this study was to evaluate breast MRI after bilateral mastectomy. Participants consisted of 48 women with prior bilateral mastectomy who underwent...
|
PMID: 21337876
PDF is available here.
Abstract
We present a case of a patient with recurrent angiosarcoma, who required total anterior chest wall reconstruction. This was achieved using bilateral pedicled SEA perforator flaps for complete coverage. To our knowledge, this is the first documented case of bilateral pedicled perforator flap reconstr...
|
PMID: 21237735
PDF is available here.
Abstract
To determine the usefulness of ultrasonography in the assessment of post radiotherapy skin changes in postmastectomy breast cancer patients.
|
PMID: 21261940
PDF is available here.
Abstract
Because metaplastic carcinoma of the breast encompasses a great variety of histopathology, diagnostic challenges abound, especially within the realm of cytology. The authors compiled and studied an eight-case series comprised of metaplastic breast carcinomas and lesions initially suspicious cytologic...
|
PMID: 21244696
PDF is available here.
Abstract
The extremely low incidence of EGFR protein expression and gene amplification in Saudi breast cancer patients as compared to Western populations is most probably ethnically related as supported by our previous finding in the same cohort of a spectrum of molecular breast cancer types that is unique t...
|
PMID: 21702909
PDF is available here.
Gokulakkrishna G Subhas,
Asha J AJ Shah,
Aditya A Gupta,
Jonathan J Cook,
Linda L Dubay,
Sumet S Silapaswan,
Ramachandra R Kolachalam,
William W Kestenberg,
Lorenzo L Ferguson,
Michael J MJ Jacobs,
Yousif Y Goriel and
Vijay K VK Mittal
Abstract
We reviewed our third and fourth breast re-excision cases, with an analysis of various factors used in making this decision. A retrospective analysis identified 585 patients who underwent re-excision surgery for positive or close margins of invasive carcinoma or ductal carcinoma in situ (DCIS). Of t...
|
PMID: 21675615
PDF is available here.
Abstract
We evaluated myoepithelial cells and collagen IV, a basement membrane component, in 40 IPCs from 39 (35 female and 4 male) patients and assessed their clinical management and follow-up. The mean patient age at diagnosis was 68 years, and the mean tumor size was 1.8 cm. Thirteen cases were pure IPC,...
|
PMID: 21084964
PDF is available here.
Abstract
Variation in rates of breast reconstruction after mastectomy has raised concerns about the quality of decisions about reconstruction. The authors sought to evaluate patient decision making about reconstruction, using a validated measure of knowledge and preferences related to reconstruction.
A cross...
|
PMID: 21200195
PDF is available here.
Abstract
Reconstruction after mastectomy has become an integral part of breast cancer treatment. The effects of psychological factors on quality of life after reconstruction have been poorly investigated. The authors examined clinical and personality characteristics related to quality of life in patients rec...
|
PMID: 21200194
PDF is available here.
Abstract
Necrosis with partial loss of mastectomy flaps is an all-too-common complication of otherwise advantageous skin-sparing mastectomies. Central to the problem of predictable flap viability is the thickness of the skin flaps. Seeking a balance between the preservation of adequate flap thickness and mai...
|
PMID: 21200196
PDF is available here.
Abstract
The majority of patients with cancer use some form of complementary or alternative medicine. External qigong treatment (EQT), classified as a bioenergy therapy, is one such approach that patients combine with conventional medicine or, in some cases, use in place of conventional medic...
|
PMID: 21106615
PDF is available here.
Abstract
The aim of this study was to evaluate the efficacy and safety profile of 4 dose-dense cycles of docetaxel followed by 3 cycles of FEC100 neoadjuvant chemotherapy in patients with operable advanced breast cancer.
Women were treated by 4 cycles of 100 mg/m² docetaxel every 2 weeks, followed by 3 cycl...
|
PMID: 20042972
PDF is available here.
Abstract
This study was conducted to test the hypothesis that surgery induces changes at the expression level of genes implicated in metastasis, thus leading to accelerated postoperative metastatic tumor growth.
Surgical resection of the primary tumor is a necessary and effective treatment for breast cancer...
|
PMID: 21107114
PDF is available here.
Abstract
We report a case of recurrent breast cancer with solitary lung metastasis that has shown no recurrence with treatment by trastuzumab alone after partial resection of the right lung upper lobe. A 56-year-old woman, who presented with left breast cancer, underwent quadrantectomy and axillar lymph node...
|
PMID: 21160267
PDF is available here.
Abstract
Health care disparities have been documented in rural populations. The authors hypothesized that breast cancer patients in urban counties would have higher rates of postmastectomy breast reconstruction relative to patients in surrounding near-metro and rural counties.
The authors used the Surveillan...
|
PMID: 21124121
PDF is available here.
Abstract
Unfulfilled expectations can lead to patient dissatisfaction with surgical outcomes. Understanding expectations allows surgeons to identify those patients who hold inaccurate expectations preoperatively, and to reset those expectations through focused preoperative education. The purpose of this stud...
|
PMID: 21124122
PDF is available here.
Abstract
The postmastectomy reconstruction of large and/or ptotic breasts poses a more difficult aesthetic challenge than the reconstruction of small or moderately sized breasts because of an excessively large skin envelope in both horizontal and vertical dimensions. The Wise-pattern skin excision best addre...
|
PMID: 21124123
PDF is available here.
Abstract
We tested the hypothesis that patients who receive combined propofol/paravertebral anesthesia-analgesia (propofol/paravertebral) exhibited reduced levels of protumorigenic cytokines and matrix metalloproteinases (MMPs) and elevated levels of antitumorigenic cytokines compared with patients receiving...
|
PMID: 20975461
PDF is available here.
Abstract
Patients are surviving longer with cancer due to early detection and improvements in treatment. With longer survival, quality of life becomes very important. While improvements in treatment add years to the life of patients diagnosed with cancer, rehabilitation can add life to those years.
|
PMID: 21301657
PDF is available here.
Abstract
The first patient was a 59-year-old woman who was diagnosed with invasive scirrhous carcinoma. The tumor was estrogen receptor (ER)-positive, progesterone receptor (PgR)-positive, and human epidermal growth factor receptor 2 (HER2)-positive. The patient was treated with adjuvant chemotherapy and end...
|
PMID: 21084819
PDF is available here.
Abstract
I error of 0.017. Six milligrams per injection provided a similar contrast-to-background ratio but also a higher residual background signal.
Based on this pilot study, the authors conclude that near-infrared assessment of perforator flap breast reconstruction is feasible with a light-emitting diode-...
|
PMID: 21042103
PDF is available here.
Abstract
Nipple-sparing mastectomy is gaining widespread popularity, as it could allow improved aesthetic outcome without increasing oncologic risk. To investigate the reconstructive issues experienced with immediate implant reconstruction, the authors reviewed the cosmetic outcomes of their series.
The auth...
|
PMID: 21042102
PDF is available here.
Abstract
The demand for bilateral mastectomy and immediate breast reconstruction has increased in recent years, primarily due to the development of genetic testing. The aim of this study was to evaluate if there was a difference between anatomically shaped and round permanent expandable implants in one-stage...
|
PMID: 20639801
PDF is available here.
Abstract
The purpose of this study was to demonstrate the impact of bilateral free flap breast reconstruction on the abdominal wall. This is the second installation of a two-part series. Presented here are bilateral combinations of three techniques: the muscle-sparing free transverse rectus abdominis musculo...
|
PMID: 21042100
PDF is available here.
Abstract
We discuss current knowledge regarding the recent data of breast cancer risk, screening strategies for high-risk women and medical and surgical approaches to reduce breast cancer risk. Patients with breast cancer belong to one of three groups: a. Sporadic breast cancer (75%)--patients without family...
|
PMID: 19666246
PDF is available here.
Abstract
Gallbladder carcinoma is a common malignancy in the Indian subcontinent. It commonly metastasizes through lymphatics, direct invasion, and hematogenous spread. A common extra-abdominal site of metastasis is the lungs. Simultaneous metastasis to breast and ovary is extremely rare.
This report describ...
|
PMID: 20943468
PDF is available here.
Abstract
Time to treatment significantly increased over the study time period (mean of 21.8 days in 1998, 31.3 days in 2003, 41.1 days in 2008). In 2008, the only study year in which MRI was routinely used, patients with an MRI had a longer median time to treatment of 43 days versus 32 days for those who did...
|
PMID: 20708761
PDF is available here.
Abstract
We describe three cases with extensively pretreated advanced breast cancer developing intramedullary spinal cord metastases two of whom were receiving trastuzumab, one of whom was a male. As therapeutic advances increase overall survival for patients with metastatic breast cancer, patterns of diseas...
|
PMID: 20919834
PDF is available here.
Abstract
Clinical complete, partial and no response were observed in 13 (26%), 24 (48%) and 11 (22%) patients, respectively (overall response rate: 74%). The number of chemotherapy cycles was found to be an independent predictor of a pathologic complete response. CONCLUSION: The combination of gemcitabine-do...
|
PMID: 20944176
PDF is available here.
Susan M Domchek,
Tara M Friebel,
Christian F Singer,
D Gareth Evans,
Henry T Lynch,
Claudine Isaacs,
Judy E Garber,
Susan L Neuhausen,
Ellen Matloff,
Rosalind Eeles,
Gabriella Pichert,
Laura Van t'veer,
Nadine Tung,
Jeffrey N Weitzel,
Fergus J Couch,
Wendy S Rubinstein,
Patricia A Ganz,
Mary B Daly,
Olufunmilayo I Olopade,
Gail Tomlinson,
Joellen Schildkraut,
Joanne L Blum and
Timothy R Rebbeck
Abstract
Among a cohort of women with BRCA1 and BRCA2 mutations, the use of risk-reducing mastectomy was associated with a lower risk of breast cancer; risk-reducing salpingo-oophorectomy was associated with a lower risk of ovarian cancer, first diagnosis of breast cancer, all-cause mortality, breast cancer-...
|
PMID: 20810374
PDF is available here.
Abstract
Skin-sparing mastectomy has been associated with flap ischemia and necrosis. Current clinical methods for assessment of flap viability following mastectomy are largely subjective and lack objective data to guide intraoperative decisions. Intraoperative laser-assisted indocyanine green angiography (L...
|
PMID: 20539977
PDF is available here.
Abstract
We present a case of an otherwise healthy 37-year-old woman, a BRCA-1 gene mutation carrier, who was evaluated several months after bilateral mastectomies with deep inferior epigastric perforator (DIEP) flap breast reconstruction with open wounds on the right DIEP flap. Multiple interventions were e...
|
PMID: 20535668
PDF is available here.
Abstract
Persistent postsurgical pain (PPSP) after surgery for breast cancer has a prevalence of 20% to 52%. Neuroplastic changes may play a role in the aetiology of this pain. The principal objective of this study was to examine the relationship between acute pain after surgery for breast cancer and the lik...
|
PMID: 20639740
PDF is available here.
Abstract
The results show that survival after breast cancer surgery is significantly associated with high volume providers.
Copyright (c) 2010 Elsevier Ltd. All rights reserved....
|
PMID: 20621432
PDF is available here.
Abstract
Four thousand nine hundred fifty-five breast cancer procedures were recorded synoptically; greater than 80% of cases provincially. Method of breast cancer detection was 49%, 45% and 4% by screening radiology, patient or family, and physician, respectively. Pathologic diagnoses were via core or mammo...
|
PMID: 20609548
PDF is available here.
Abstract
An increasing number of women presenting with early stage breast cancer or a strong family history are choosing mastectomy as a therapeutic or prophylactic treatment option. In these selected patients, conservation of the nipple areolar complex is considered to improve cosmesis and body image. Incis...
|
PMID: 20606592
PDF is available here.
Abstract
Our procedure allows for a skin-sparing mastectomy (SSM type V) with immediate reconstruction, achieving a natural breast shape also in this group of patients previously excluded....
|
PMID: 20657195
PDF is available here.
Abstract
In this study, partial breast reconstruction was undertaken after breast conservation therapy using mini abdominal free flaps on both an immediate and delayed basis.Patient demographics, oncologic status, reconstructive data, and complications were collected from medical records.Twelve patients (age...
|
PMID: 20606581
PDF is available here.
Abstract
BCT was performed in 30% of patients. Isolated local recurrence rate for BCT and mastectomy was 0% and 10.6%, respectively (P = .02). Isolated regional recurrence rate for BCT and mastectomy was 1.6% and 1.4%, respectively (P = .61). Neither concomitant locoregional and distant recurrence rate (P =...
|
PMID: 20580045
PDF is available here.
Abstract
To evaluate the prognostic value of determining estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 (HER2) expression in node-positive breast cancer patients treated with mastectomy.
|
PMID: 20638197
PDF is available here.
Abstract
We identified 233,754 patients diagnosed with ductal carcinoma in situ or stage I to III unilateral breast cancer from 2000 to 2006. The proportion of women treated with mastectomy decreased from 40.8% in 2000 to 37.0% in 2006 (P < .001). These patterns were maintained across patient and tumor facto...
|
PMID: 20548000
PDF is available here.
Abstract
The number of AxLNs recovered at ALND does not appear to be affected by neoadjuvant chemotherapy. Surgeons with oncologic training appear to retrieve more AxLNs.
Copyright (c) 2010 American Cancer Society....
|
PMID: 20564124
PDF is available here.
Abstract
We earlier evaluated the relationship of 653 triple negative breast cancers (TNBC) with basal immunophenotypic expression by using antibodies to basal cytokeratins (CK5/6, CK14, CK17, 34betaE12), p63, smooth muscle actin (SMA), epidermal growth factor receptor, and CD117, and found that a triple pan...
|
PMID: 20495445
PDF is available here.
Abstract
Study findings will be useful to establish priorities in planning nursing interventions to enhance HRQOL in care of women with breast cancer. IMPLICATIONS FOR NURSING: Nursing interventions can be provided to Korean women with breast cancer who are not religious, who are older, single or widowed, or...
|
PMID: 20591793
PDF is available here.