Abstract
We reported a 34 years old caucasian woman with acute renal failure and hypercalcemia as onset of splenic lymphoma in absence of abnormal levels of serum vitamin D and PTHrP. Because of dramatic recovery of renal function and hypercalcemia after splenectomy, we can speculate that main mechanism of h...
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PMID: 21780556
PDF is available here.
Abstract
Gastrointestinal stromal tumors (GISTs) may arise in any part of the gastrointestinal tract; extra-gastrointestinal locations are extremely rare. Only a few cases of extragastrointestinal stromal tumor arising from the pancreas were reported. None of the reports described a long-term...
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PMID: 21669581
PDF is available here.
Abstract
We report a case of 22 years old female who presented with history of 2 years abdominal pain and gradual distension. Ultrasound and computed tomography (CT) both were suggestive of splenic cyst. Laboratory tests show thrombocytopenia with platelets count of 97000 per cubic millimeter and anemia with...
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PMID: 21453626
PDF is available here.
Abstract
We report a case who was injured during a soccer game who underwent abdominal surgery. Distal subtotal pancreatectomy, splenectomy, cholecystectomy, and choledochotomy + T-tube drainage were performed. He was discharged on the postoperative seventh day without any complication....
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PMID: 21644099
PDF is available here.
Aurora Burgos AB García,
Eduardo Martín EM Arranz,
Rafael Rey RR Sanz,
Eva Marín EM Serrano,
María Dolores Martín MD Arranz,
Paloma González PG Sanz-Agero,
Elena Collantes EC Bellido,
José Juan Pozo JJ Kreilinger,
Luis Asensio LA Prianes,
Luis Alberto Mata LA Juberías,
Juan Pedro Pérez JP Robledo,
José Manuel Suárez JM Parga and
José María Segura JM Cabral
Abstract
Signet ring cell carcinoma of the ampulla of Vater is a rare entity and less than 20 cases have been described in the literature. We report the cases of two patients with this disease and provide a literature review of previous studies.
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PMID: 21376425
PDF is available here.
Abstract
To assess the outcome of giant cell hepatitis combined with autoimmune hemolytic anemia in early childhood.
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PMID: 21349541
PDF is available here.
Abstract
I and II splenic injuries that failed NOM occurred by 24 hours. Grade 3 and 4 injuries that failed NOM occurred by 150 hours. SE was protective against splenectomy (Hazard Ratio (HR) 0.18, 95% confidence interval: 0.06-0.55, P = 0.004), whereas splenic injury grades III or higher was associated with...
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PMID: 21337883
PDF is available here.
Abstract
It is difficult to treat patients with cirrhosis-associated hepatitis C with pegylated interferon (PEG-IFN) and ribavirin because of thrombocytopenia-related hypersplenism. Both safety and clinical efficacy were retrospectively analyzed for patients who underwent a laparoscopic splen...
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PMID: 21337875
PDF is available here.
Abstract
We conducted this study to quantify the burden of residual skeletal disease and to explore putative relationships between clinical, radiologic, and biochemical factors and bone sequelae associated with disability.Consecutive adult patients attending 3 referral centers in the United Kingdom were invi...
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PMID: 21200186
PDF is available here.
Abstract
The objective of this systematic review and meta-analysis was to assess the outcomes after angioembolization in blunt trauma patients with splenic injuries and to examine specifically the impact of the technique used. Studies evaluating adult trauma patients who sustained blunt splenic injuries mana...
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PMID: 21217497
PDF is available here.
Abstract
Immune thrombocytopenia (ITP) is caused by immune-mediated platelet destruction and reduced platelet production. The aim of this review article is to provide an updated overview of pathophysiology and new therapeutic modalities in ITP.
The article is based on literature identified through a non-syst...
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PMID: 21052113
PDF is available here.
Abstract
Splenic artery angioembolization (SAE) is increasingly being used as an adjunct to nonoperative management for stable patients with blunt splenic injury (BSI). However, little is known about splenic immunocompetence after SAE. This study aims at assessing splenic immunocompetence after SAE for BSI....
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PMID: 21068617
PDF is available here.
Abstract
To study the management and outcome of children with extrahepatic portal vein obstruction (EHPVO) in a whole country population.
A nationwide multicenter retrospective case series of children with EHPVO was conducted. Data on demographics, radiographic studies, laboratory workup, endoscopic and surg...
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PMID: 20954284
PDF is available here.
Abstract
Hereditary stomatocytosis (HSt) is a group of haemolytic anaemias in which the common symptom is an increased permeability of the red cell membrane for monovalent cations. HSt is diagnosed really seldom and the difficulties in diagnosing are connected to the fact that the clinical presentation of in...
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PMID: 20842826
PDF is available here.
Abstract
We investigated the involvement of stromal cell-derived factor-1 (SDF-1)/CXCR4 in EPC settlement in the spleen. EPC were cultured and characterized as previous methods. Then, 1 x 10(6) EPC were labeled with DiI-LDL and intravenously infused into C57/BL6 mice. Immunohistochemical staining showed homi...
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PMID: 20524780
PDF is available here.
Abstract
Profound hemostatic changes have been observed among thalassemic patients. Thrombin activatable fibrinolysis inhibitor (TAFI) is a newly discovered protein that potentially attenuates fibrinolysis. The authors aimed to investigate plasma level of TAFI in beta-thalassemia patients in relation to clin...
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PMID: 20670166
PDF is available here.
Abstract
The endoscopically placed tattoo was easily visible upon entering the lesser sac in all 10 patients at laparoscopy. Patients with a tattoo had a shorter operative time (median, 128.5 minutes; range, 53-180) compared with patients without a tattoo (median, 180 minutes; range, 120-240; P < .01). None...
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PMID: 20554299
PDF is available here.
Abstract
We present a case of a 60-year-old female with sarcoid reactions in the spleen identified during the consecutive diagnosis and management of ovarian, breast, and thyroid carcinomas during a period of about 2 years. The symptoms and laboratory data suggestive of systemic sarcoidosis were absent excep...
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PMID: 21319598
PDF is available here.
Abstract
We will discuss the postulated mechanisms that produce a breakdown of immunologic tolerance leading to warm AIHA including the possible roles of RBC autoantigens and the complement system, the lack of effective presentation of autoantigens, functional abnormalities of B and T cells resulting in poly...
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PMID: 20656187
PDF is available here.
Abstract
Hematoxylin-eosin staining showed irreversible necrosis in the splenic coagulation area after MW ablation. As the power was increased, long-axis diameter enlarged significantly (p<.05). Short-axis diameter also tended to increase, but there were no statistical difference (p>.05). The coagulation siz...
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PMID: 19349134
PDF is available here.
Abstract
Experimental investigation, using apparatus for hydrostream dissection of tissues, was conducted. The expediency of application of a high pressure liquid stream while performance of spleen resection in experiment was proved. The stages of the organ capsule formation and parenchyma restoration in dif...
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PMID: 20825092
PDF is available here.
Abstract
We describe computed tomography and magnetic resonance imaging findings of two cases of subdiaphragmatic intraperitoneal splenosis located along the hepatic surface, mimicking neoplastic lesions....
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PMID: 19838993
PDF is available here.
Abstract
We present the only reported case of such a complication in the state of Hawai'i and the 44th reported case in the English literature. Physicians need to be more aware of the possibility of splenic rupture following colonoscopy to avoid delay of diagnosis and treatment of this life-threatening compl...
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PMID: 20535686
PDF is available here.
Abstract
We report a case of a previously well 40-year-old man who died 5 hours after hospital admission. At autopsy Waterhouse-Friderichsen syndrome was identified and Capnocytophaga canimorsus was subsequently isolated on antemortem blood cultures. Infection of humans with this organism is most often due t...
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PMID: 20407357
PDF is available here.
Abstract
We started to treat her with S-1(100mg/day day 1-14 orally), and restaging CT showed complete regression of liver and lung metastases in August 2003. In spite her complete response(CR), we continued S-1 treatment for the successive two years. No adverse reaction to chemotherapy occurred. Although CR...
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PMID: 20567121
PDF is available here.
Abstract
We present the case of a 71-year-old lady with a long history of primary myelofibrosis, which developed multiple abdominal sclerosing extramedullary hematopoietic tumors with good clinical evolution. Nonchronic myeloid leukemia myeloproliferative neoplasm included a JAK2 mutation as part of the diag...
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PMID: 20042850
PDF is available here.
Abstract
We report two rare cases in which combined transoesophageal echocardiography and vascular ultrasound examination aided in the identification of catheter-related thrombosis in two patients suffering from splenectomy-induced thrombocytosis and antiphospholipid syndrome respectively....
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PMID: 20514974
PDF is available here.
Abstract
We report 2 cases of gallstone associated with portal cavernoma in 2 girls. The first one suffered from Evans syndrome associated with congenital immune deficiency. The portal cavernoma was discovered with gallstone after splenectomy indicated because of high steroid dependence. In the second case,...
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PMID: 20303244
PDF is available here.
Abstract
Mean age at diagnosis was 54 years. ITP was revealed by hemorrhage in 65 % of the patients. Despite very low platelet count, no life threatening hemorrhage was observed. Platelet associated antibodies were found in 66 %, usually directed against GPIIb/IIIa. Corticosteroids were used as first line tr...
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PMID: 20409619
PDF is available here.
Abstract
To investigate the predictive value of combined use of D-dimer and P-selectin for splenic or portal vein thrombosis (SPVT) after splenectomy. A prospective study was carried out in 82 patients who had undergone splenectomy for portal hypertension secondary to hepatic cirrhosis. Plasma levels D-dimer...
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PMID: 20079524
PDF is available here.
George C Velmahos,
Nikos Zacharias,
Timothy A Emhoff,
James M Feeney,
James M Hurst,
Bruce A Crookes,
David T Harrington,
Shea C Gregg,
Sheldon Brotman,
Peter A Burke,
Kimberly A Davis,
Rajan Gupta,
Robert J Winchell,
Steven Desjardins,
Reginald Alouidor,
Ronald I Gross,
Michael S Rosenblatt,
John T Schulz and
Yuchiao Chang
Abstract
Nearly two-thirds of patients with grade IV or V BSI require surgery. A grade V BSI and brain injury predict failure of NOM. This data must be taken into account when generalizations are made about the overall high success rates of NOM, which do not represent severe BSI....
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PMID: 20479344
PDF is available here.
Abstract
A 62-year-old Japanese man presented with a 1-month history of inter-digestive epigastralgia. His family history included a sister with gastric cancer. Gastroendoscopy and gastrography demonstrated a type-2 tumor in the upper region of the stomach. CT scan and fluorodeoxyglucose-positron emission to...
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PMID: 20179985
PDF is available here.
Abstract
We describe a case of severe CMV mononucleosis that was acquired naturally decades after splenectomy. Together with the 2 similar cases that we reported recently, these cases all presented as initial diagnostic challenge because of a remote history of splenectomy, a prolonged febrile illness (approx...
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PMID: 20195147
PDF is available here.
Abstract
Afghanistan is a war-ravaged country surrounded by mountainous terrain. Due to the geography and harsh living conditions, people have intermarried among tribes for centuries. The right familial combinations can cause manifestations of genetic linked diseases. Thalassemia major is one of these geneti...
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PMID: 20583458
PDF is available here.
Abstract
Major pancreatic resections can be performed safely, with acceptable morbidity and mortality and good long-term results, even in middle-volume centers. However, experience is required from the part of the operating surgeon.Abbreviations: PD - pancreatoduodenectomy, DP - distal pancreatectomy, PPPD -...
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PMID: 19940794
PDF is available here.
Abstract
We review the anaesthetic implications and outcome of the first two paediatric patients with SCD to have a laparoscopic splenectomy due to repeated splenic infarcts in the Republic of Ireland....
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PMID: 20486319
PDF is available here.
Abstract
cyclin D1+ mantle zone cells surrounding neoplastic and reactive follicles (indicative of in situ mantle cell lymphoma) and BCL2-bright, histologically nonneoplastic follicles (indicative of in situ follicular lymphoma). ImmunoFISH and microdissection and polymerase chain reaction analysis documente...
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PMID: 20231612
PDF is available here.
Abstract
We describe the first case of splenic lymphangiomatosis with rapid growth during lactation in a 35-year-old woman. We also underline the difficultly in making an accurate preoperative diagnosis, despite more modern imaging techniques. Total splenectomy was considered to be the treatment needed, both...
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PMID: 20205289
PDF is available here.
Abstract
There is paucity of data on long-term probability of remission in chronic idiopathic thrombocytopenic purpura (ITP). Aim was to study the course and factors influencing remission of chronic ITP. Chronic ITP was defined as thrombocytopenia persisting >6 months following initial diagno...
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PMID: 19908301
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.
Abstract
This study aimed to evaluate whether laparoscopic splenectomy (Lap-Sp) contributes to the completion and curability of combined peginterferon and ribavirin (peg-IFN + RIB) therapy for cirrhotic patients with pancytopenia due to hypersplenism.
From December 2004 to Sep...
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PMID: 19690915
PDF is available here.