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Directly Observed Therapy (0):
Recent article
Directly Observed Therapy
Abstract
UNIMMAP triggered the same hemoglobin dose response with half the amount of iron as provided by IFA treatment. The benefit of iron supplements in nonanemic women is unclear. Despite micronutrient supplementation, anemia remained highly prevalent during gestation, partly because of physiologic hemodi...
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PMID: 21367950
PDF is available here.
PDF is available here.
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Abstract
Abstract
Patients receiving DOTS undergo periodic follow-up sputum examination, which aids in monitoring response to treatment. Continued or new smear positivity at follow up examination entails extension of intensive phase or change in treatment category and the need for culture and drug susceptibility test....
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PMID: 21644391
PDF is available here.
PDF is available here.
Abstract
The aim of tuberculosis treatment is to cure the individual patient with antituberculosis drugs (ATT) in a short time without emergence of drug resistance. The anti tuberculosis drugs are selected in a combination to attack all the subpopulations of tubercle bacilli with first line drugs which includ...
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PMID: 21049292
PDF is available here.
PDF is available here.
Abstract
Tuberculosis (TB) is a major health problem in Nigeria. The country is currently fourth among the 22 high-burden countries (HBCs) of the world, with an incident of all new cases of 311/100,000 population per year out of which 137/100,000 population are smear positive and prevalence o...
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PMID: 21834257
PDF is available here.
PDF is available here.
Abstract
Abstract
To summarise the effectiveness of adding supervised exercises to conventional treatment compared with conventional treatment alone in patients with acute lateral ankle sprains.
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PMID: 20978065
PDF is available here.
PDF is available here.
Abstract
Abstract
Multi Drug Resistant Tuberculosis (MDR-TB) and Extensively Drug Resistant Tuberculosis (XDR-TB) are posing a threat to the control of tuberculosis. The first WHO-IUATLD antituberculosis drug resistance surveillance carried out in 1994 in 35 countries reported the median prevalence of primary and acq...
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PMID: 21141336
PDF is available here.
PDF is available here.
Southern Medical Journal (103)9 2010
Abstract
Five secondary TB cases were associated with the index case. Of 369 contacts of the index case, 189 (51%) were evaluated. Of those, 97 (51%) had positive tuberculin skin test (TST) results, 79 (81%) began therapy for latent TB infection (LTBI), and 38 (48%) completed LTBI therapy. CONCLUSION: Despit...
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PMID: 20689483
PDF is available here.
PDF is available here.
Abstract
We assessed the quality of TB care delivery in Afar Region of Ethiopia.
A descriptive cross sectional health institution based survey with both semi-structured and structured questionnaires was employed. A mix of complementary techniques was administered Data were collected between 5th February and...
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PMID: 21073080
PDF is available here.
PDF is available here.
Abstract
Abstract
Tools for effective TB control have been available for years. Case finding, active medications, case management and directly observed therapy are the foundations for the management of TB. The current TB epidemic, centered in resource-limited settings is fueled by the HIV-1 epidemic. Lack of ability...
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PMID: 20586565
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)6 2010
Abstract
Inadequate adherence to therapy is not an uncommon problem in the management of chronic asthma. Insufficient information, unmet expectations and medication side effects are all important factors that contribute to poor adherence to therapy. In addition to optimal patient education, the use of asthma...
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PMID: 20512754
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)6 2010
Abstract
We present several examples from clinical practice and the literature. Anticipation, recognition and appropriate countermeasures are important elements for the prevention of non compliance, which may target the pharmacotherapy itself, the patient, or the health system providing the therapeutic frame...
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PMID: 20512751
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)6 2010
Abstract
To attain optimal therapeutic effects, a drug must reach its target structure in sufficiently high concentrations for a sufficiently long time. Lacking or insufficient response may be due to insufficient drug concentrations. It may be caused either by non compliance of the patient or by reduced abso...
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PMID: 20512752
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)6 2010
Abstract
We present factors associated with medication non adherence using the five adherence dimensions suggested by the World Health Organization as well as the subjective appraisal regarding medication intake of the patient as suggested by the National Institute of Health and Clinical Excellence in the UK...
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PMID: 20512748
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)6 2010
Abstract
Improving patient compliance poses a daily challenge to all healthcare professionals, and especially to the patients, who must accept the need for drug treatment, come to terms with the selected medication and, finally, integrate it into their daily life - at most, this can represent a lifelong nece...
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PMID: 20512750
PDF is available here.
PDF is available here.
Therapeutische Umschau (67)6 2010
Abstract
Ambulatory pharmacotherapy is marked by many deviations, mostly downward, in drug dosing from prescribed instructions. Soundly compiled dosing histories date from 1977, based on electronic time-stamping of medication 'events': package entry times, done first with eyedrop dispensers for glaucoma drug...
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PMID: 20512749
PDF is available here.
PDF is available here.
Abstract
We performed a meta-analysis and systematic review to assess the effect of DOT-HAART on adherence and virologic and immunologic response.
We performed a comprehensive search through August 2009 to identify peer-reviewed controlled studies that involved outpatient DOT-HAART among adults and reported...
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PMID: 20375848
PDF is available here.
PDF is available here.
Abstract
Despite being free of charge, treatment adherence to 7-day primaquine for the radical cure of Plasmodium vivax was estimated at 62.2% among patients along the Iquitos-Nauta road in the Peruvian Amazon. The principal reason for non-adherence was the perceived adverse effects related to local humoral...
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PMID: 20519594
PDF is available here.
PDF is available here.
Abstract
We aimed to evaluate the incremental cost-effectiveness of engaging private practitioners (PPs) to refer tuberculosis (TB) suspects to public health centers in Jogjakarta, Indonesia. Effectiveness was assessed for TB suspects notified between May 2004 and April 2005. Private practitioners referred 1...
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PMID: 20519613
PDF is available here.
PDF is available here.
Pediatrics (125)6 2010
Abstract
Antibiotic prescribing patterns for the treatment of S aureus infections have changed significantly during the past decade, reflecting the emergence of community-associated MRSA. Clindamycin is now the most commonly prescribed antibiotic for S aureus infections among hospitalized children. The subst...
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PMID: 20478934
PDF is available here.
PDF is available here.
Abstract
This study had as objective to analyze the strengths and weaknesses of the Directly Supervised Treatment strategy (DOTS) from the view of patients and workers from the North, West and East Health Departments of São Paulo. The analysis of the statements was based on the Social Determination Theory o...
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PMID: 20642060
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
To compare tuberculosis cure rates among patients supervised by household members or health care workers.
Prospective cohort study of 171 patients treated by the program in Vitoria, Southeastern Brazil, from 2004 to 2007. Each patient was followed-up for six months until the end of the treatment. Of...
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PMID: 20339634
PDF is available here.
PDF is available here.
Abstract
Tuberculosis has re-emerged as a public health concern in high-income countries in the last few decades. The European region accounts for only 5% of world TB cases. The incidence of new TB cases in Europe varies from very low rates in Scandinavian countries (six to eight cases/100,00...
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PMID: 20406085
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Enhancing financial resources for TB control and effective involvement of human resources are crucial to achieving success with the DOTS strategy in rural China....
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PMID: 20202302
PDF is available here.
PDF is available here.
The Nurse Practitioner (35)3 2010
Abstract
Abstract
Abstract
Our experience suggests that m-DOT services could be implemented widely and are acceptable if delivered with adequate attention to coordination, provision of a broad set of interventions, shifting tasks to less-specialised workers and integration within the health system. m-DOT programmes should uti...
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PMID: 20390497
PDF is available here.
PDF is available here.
Abstract
We investigated the emergence and evolution of drug-resistant tuberculosis (TB) in an HIV co-infected population at a South African gold mine with a well-functioning TB control program. Of 128 patients with drug-resistant TB diagnosed during January 2003-November 2005, a total of 77 had multidrug-re...
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PMID: 20113557
PDF is available here.
PDF is available here.
Abstract
From November 2000 to December 2004, respectively 339 and 311 pulmonary TB cases were enrolled and 1003 and 960 household were identified in DOTS and DOTS-A communities. Among contacts from DOTS-A communities, 26 (4%) had active TB diagnosed and treated, 429 (61.3%) had LTBI detected and 258 (60.1%)...
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PMID: 20074412
PDF is available here.
PDF is available here.
Abstract
Our data indicated that DNA sequencing of specific codons of the rpoB gene should be effective for predicting RMP resistance and MDR-TB in rural China....
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PMID: 20074413
PDF is available here.
PDF is available here.
Abstract
Culture and drug susceptibility testing results of 2816 tuberculosis (TB) patients from across India who had failed repeated treatments from 2001 to 2004 were retrospectively analysed at the Tuberculosis Research Centre, Chennai. Of 1498 (53%) identified as having multidrug-resistant TB (MDR-TB), 67...
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PMID: 20074419
PDF is available here.
PDF is available here.
Abstract
Over a 15-year period, 18 TB cases in Alberta and multiple cases in the Northwest Territories were determined to be due to the same strain. One patient was diagnosed at death; all others completed directly-observed therapy (DOT). Case-level analysis revealed that patients were highly mobile with tra...
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PMID: 20737810
PDF is available here.
PDF is available here.
Abstract
This observational cohort study was conducted among HIV-infected, antiretroviral therapy (ART) naive children in Phnom Penh, Cambodia, to evaluate the feasibility and efficacy of highly active antiretroviral therapy (HAART) delivered using a modified directly observed therapy (MDOT) protocol. From Au...
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PMID: 20578491
PDF is available here.
PDF is available here.
Tuberkuloz ve toraks (58)1 2010
Abstract
Directly observation therapy (DOT) has been accepted as the basic method for controlling tuberculosis. The present study aimed to determine the risk factors that affect sputum culture conversion rate in the DOT managed and non-DOT managed hospitalized patients. The study was included 50 cases with p...
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PMID: 20517728
PDF is available here.
PDF is available here.
Integration of informal medical practitioners in DOTS implementation to improve case detection rate.
Abstract
Out of 64 health care providers there were a drop out of 6 leaving 58 informal registered medical practitioners (36 homeopathic/22 Hakims) who referred 54 cases, of these 16 cases were actual suspects. Two out of these 16 (12.5%) were Tuberculosis positive. One was Sputum D/S positive and the other...
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PMID: 20055277
PDF is available here.
PDF is available here.
Abstract
INTRODUCTION: Tuberculosis (TB) remains a major public health problem in the Western Pacific Region. More than 20% of the global burden of TB is found in the Region. In 2007, the latest year for which data is available, there were an estimated 1.9 million incident cases (109 per 100,000 population)....
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PMID: 20143671
PDF is available here.
PDF is available here.
Abstract
Multi-drug resistant (MDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least two anti-tubercular drugs Isoniazid and Rifampicin. Recent surveillance data have revealed that prevalence of the drug resistant tuberculosis has risen to th...
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PMID: 21209520
PDF is available here.
PDF is available here.
Malaria Journal (9) 2010
Abstract
Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug and adherenc...
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PMID: 21040545
PDF is available here.
PDF is available here.
Food and nutrition bulletin (30)4 Suppl 2009
Abstract
Multivitamin supplementation use among pregnant women is as effective as iron-folic acid in improving anemia status and appears to have other benefits for maternal and child nutritional status....
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PMID: 20120790
PDF is available here.
PDF is available here.
Abstract
We started cooperation between Higashihiroshima Medical Center and Onomichi Medical Association to provide better medical care for tuberculosis patients through LCP. The request of health care workers for LCP by questionnaire study were i) schedule of laboratory examination to check adverse reaction...
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PMID: 20077860
PDF is available here.
PDF is available here.
Abstract
Abstract
The results showed that the intervention had a significant impact on the understanding of disease and its management (X(2) =11.842 p<0.05), DOTS and increased awareness (X(2) =17.289 p<0.05, X(2) =10.461 p<0.05), knowing the side effects of anti-TB drugs (X(2) =10.157 p<0.05), the meaning of resista...
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PMID: 20037616
PDF is available here.
PDF is available here.
Abstract
Abstract
In areas hyperendemic for TB, DOTS should be prioritized for groups at greater risk of treatment abandonment or death, and the investigation of TB contacts should be intensified....
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PMID: 19918633
PDF is available here.
PDF is available here.
Abstract
Mean age was 10.8 years (median age 12.2 years) with more females (51.9%) than males (48.1%) chi1(2) = 0.15; P = 0.698 (NS). In the age group of 0-5, 6-10 and 11-14 years, there were 15.1%, 30.2% and 54.7% patients respectively. Fever was the commonest symptom (98.1%) followed by cough (77.4%) and c...
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PMID: 20469730
PDF is available here.
PDF is available here.
Abstract
Between January 2002 to December 2006, 130 patients initiated treatment, of whom 24 died. Among rest 106 patients, 63 (59%) patients could be traced: 51 were currently alive while 12 had died. The 51 alive patients had completed a mean (+/- S.D.) post treatment period of 24 +/- 14.7 months ranging f...
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PMID: 20469732
PDF is available here.
PDF is available here.
Abstract
Abstract
Perianal tuberculosis, without the presence of any previous or active pulmonary infection, is extremely rare. A wide range of differential diagnosis for perianal ulcers might be one reason for a possible delay in establishing this diagnosis.
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PMID: 20469737
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
In subjects aged >or=10 years, the 2007 prevalence of radiographic PTB was 6.3% (95%CI 5.5-7.1), bacteriologically confirmed PTB was 6.6 per 1000 (95%CI 5.1-8.1) and sputum smear-positive PTB was 2.6/1000 (95%CI 1.7-3.6). For the total population, the corresponding estimates were respectively 4.7%,...
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PMID: 19793426
PDF is available here.
PDF is available here.
Abstract
Age above 40 years is a significant risk factor for death in patients of tuberculosis. There was a significant difference in survival curves of the three DOTS categories and age groups....
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PMID: 19584488
PDF is available here.
PDF is available here.