Abstract
We believe that knowledge on the recent progress in TH for OHCA is useful for neurosurgeons, because feedback of information obtained in the treatment of OHCA may revitalize the interest in TH for neurosurgical disorders, particularly TBI.
A review of the literature was conducted wit...
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PMID: 21300001
PDF is available here.
Abstract
We conducted a search of the CINAHL (2000 to April 2009), Medline (2000 to April 2009), Embase (2000 to April 2009) and the Cochrane Register of Controlled Trials (2000 to April 2009) databases for randomized controlled trials published in English, Spanish and Portuguese. The primary outcome measure...
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PMID: 20546353
PDF is available here.
Abstract
Inadvertent perioperative hypothermia impairs postoperative outcome in surgical patients due to ischemic myocardial events, wound infections and coagulation disorders. Body core temperature should be assessed 1-2h preoperatively and continuously during surgery. To prevent hypothermia patients and nu...
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PMID: 20232270
PDF is available here.
Abstract
We describe a case of severe accidental hypothermia (core body temperature 23.2 degrees C) successfully treated with hemodialysis in a diabetic patient with preexisting renal insufficiency. Consensus exists about cardiopulmonary bypass as the treatment of choice in cases of severe accidental hypothe...
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PMID: 20665964
PDF is available here.
Abstract
A seventy-year-old male was brought to the emergency department severely hypothermic with a core temperature of 27 degrees C. He had sustained circulation and was actively rewarmed for 6,5 hours using central veno-venous haemofiltration. The rewarming was uneventful and the patient was discharged wi...
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PMID: 20184821
PDF is available here.
Abstract
Intranasal balloon catheters can be used for therapeutic hypothermia initiation, maintenance and rewarming during CPR and after successful resuscitation in pigs....
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PMID: 19912127
PDF is available here.
Abstract
Induction of mild therapeutic hypothermia early after return of spontaneous circulation improves prognosis of cardiac arrest survivors. Rapid cooling of the patients and correct maintainance of the target therapeutic temperature followed by controlled slow rewarming can be achieved by several noninv...
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PMID: 20017438
PDF is available here.
Abstract
This study investigated whether a modified Cold Provocation Test could distinguish between 86 normal subjects and 31 patients with Raynaud's phenomenon or 59 with hand arm vibration syndrome (HAVS). Of the HAVS subjects, 56 were seen for medical reports as they were involved in litigation. Their ass...
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PMID: 19687085
PDF is available here.
Abstract
We recommend the use of charcoal heaters, chemical heating pads, or hot-water bags as effective means for treating cold patients in the field or during transport to definitive care....
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PMID: 19499476
PDF is available here.
Abstract
We report that patients with INCL have lower baseline body temperature and during general anesthesia, despite rewarming interventions, are at increased risk for hypothermia and bradycardia. This suggests a previously unknown INCL phenotype, impaired thermoregulation. Therefore, when anesthetizing th...
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PMID: 19608805
PDF is available here.
Abstract
Increasing evidence in animal models and clinical trials for stroke, hypoxic encephalopathy for children, and traumatic brain injury have shown that mild hypothermia may attenuate ischemic damage and improve neurological outcome. However, it is less clear if mild intraoperative hypothermia during va...
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PMID: 19409003
PDF is available here.
Abstract
We revisit the relatively limited literature examining the issue of hypothermia and differing rewarming rates following TBI. Considering both experimental and clinical literature, evidence is presented that the rate of posthypothermic rewarming is an important variable for influencing the protective...
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PMID: 19292695
PDF is available here.
Abstract
The association of different warming methods delayed the beginning and reduced the severity of intraoperative hypothermia, but it did not reduce the complaints of feeling cold and tremors....
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PMID: 19374216
PDF is available here.
Abstract
Moderate hypothermia followed by a rapid re-warming procedure was safe and effective in the proximal arch replacement for AAD....
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PMID: 19047777
PDF is available here.
Abstract
We report a case of a profoundly hypothermic newborn with a core temperature of 25 degrees C with a successful recovery and normal neurological outcome at 3 and 6 months. This term male infant had been exposed to a temperature of -3 degrees C for approximately 30 min. Slow re-warming, using external...
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PMID: 19006529
PDF is available here.
Abstract
Endovascular warming is safe, simple to use, and obviates the need for uncomfortably warm operating room temperatures. The Thermogard system compared favorably with conventional methods for warming during OPCAB....
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PMID: 19101312
PDF is available here.
Abstract
The efficacy of forced-air warming systems is primarily determined by the blanket. Modern power units provide sufficient heat energy to maximize the ability of the blanket to warm the patient. Optimizing blanket design by optimizing the mean temperature gradient between the blanket and the manikin (...
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PMID: 19095849
PDF is available here.
Abstract
We demonstrated that, using either a resistive heating-blanket or forced-air warming systems, patients ended surgery in mild hypothermia after elective total hip replacement, but without significant differences between these two warming devices....
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PMID: 19095850
PDF is available here.
Abstract
Central venous pressure, rewarming time, and fluid replacement volume required on the first day are predictors of postoperative course....
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PMID: 19177861
PDF is available here.
Abstract
The mean time of initiation of PPCPB after admission was 41.9 +/- 7.9 minutes. The rewarming speed was 4.0 +/- 1.5 degrees C/h. A 100% success rate was achieved after the rewarming procedure, whereas the rate of weaning from PPCPB was 91.7%. Vf during rewarming developed in one case; however, electr...
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PMID: 19077632
PDF is available here.
Abstract
Cold exposure injuries comprise nonfreezing injuries that include chilblain (aka pernio) and trench, or immersion, foot, as well as freezing injuries that affect core body tissues resulting in hypothermia of peripheral tissues, causing frostnip or frostbite. Frostbite, the most serious peripheral in...
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PMID: 19056919
PDF is available here.
Abstract
In the endovascular cooling group the target temperature was reached significantly faster (154 +/- 97 min vs. 268 +/- 95 min, p = 0.0002) and showed stable and controlled maintenance of cooling therapy (deviation from target temperature: 0.189 +/- 0.23 degrees C vs 0.596 +/- 0.61 degrees C, p = 0.00...
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PMID: 18958431
PDF is available here.
Abstract
Randomised controlled trials have demonstrated that mild hypothermia reduces mortality and morbidity in full-term neonates who experience perinatal asphyxia. Hypothermia can be applied to the head or entire body, maintaining a temperature of 33-34 degrees C for 72 hours. Treatment should be started...
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PMID: 19009805
PDF is available here.
Abstract
Hypothermia is one of the most common complications experienced by surgical patients. Better postoperative patient outcomes are achieved when normothermia is maintained. Perioperative nurses should understand how to maintain normothermia, the causes of hypothermia, and adverse patient outcomes that...
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PMID: 18819204
PDF is available here.
Abstract
The membrane OXM--1500 infant oxygenator, tested in sheep, showed adequate oxygenation capacity, CO2 removal capacity, and small alteration of haemoglobin and platelets without significant decrease of leucocytes, as expected. Heat exchanger connected to the oxygenator was efficient in temperature ch...
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PMID: 19082324
PDF is available here.
Abstract
The durations of cerebral protection (group I, 75.8 minutes, vs group II, 18.8 minutes), cardiopulmonary bypass (I, 201.2, vs II, 84.4 minutes), and overall operation (I, 425.6, vs II, 148.6 minutes) were significantly shorter in group II. In group I, 5 patients had complications of cerebral damage...
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PMID: 18692662
PDF is available here.
Abstract
A wet forced-air warming blanket is ineffective at maintaining normothermia. Once wet, the warming blanket resulted in cooling similar to the control group....
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PMID: 18422882
PDF is available here.
Abstract
We describe the use of continuous venovenous haemodialysis (CVVHD) as a rewarming method in a hypothermic, multiply injured patient. CVVHD achieved rapid rewarming and holds advantages over established rewarming methods in the trauma setting....
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PMID: 18658015
PDF is available here.
Abstract
Treatment of the hypothermic patient depends more on the clinical condition than on the core temperature. Unconscious patients need thorough investigation, and they can often be rewarmed with warm water in the pleural cavities. Cardiac arrest requires cardio pulmonary rescue until rewarming can be e...
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PMID: 18534162
PDF is available here.
James S Hutchison,
Roxanne E Ward,
Jacques Lacroix,
Paul C Hébert,
Marcia A Barnes,
Desmond J Bohn,
Peter B Dirks,
Steve Doucette,
Dean Fergusson,
Ronald Gottesman,
Ari R Joffe,
Haresh M Kirpalani,
Philippe G Meyer,
Kevin P Morris,
David Moher,
Ram N Singh,
Peter W Skippen and
Hypothermia Pediatric Head Injury Trial Investigators and the Canadian Critical Care Trials Group
Abstract
In children with severe traumatic brain injury, hypothermia therapy that is initiated within 8 hours after injury and continued for 24 hours does not improve the neurologic outcome and may increase mortality. (Current Controlled Trials number, ISRCTN77393684 [controlled-trials.com].).
Copyright 2008...
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PMID: 18525042
PDF is available here.
Abstract
Increasing evidence suggests that induction of mild hypothermia (32-35 degrees C) in the first hours after an ischaemic event can prevent or mitigate permanent injuries. This effect has been shown most clearly for postanoxic brain injury, but could also apply to other organs such as the heart and ki...
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PMID: 18539227
PDF is available here.
Abstract
The higher apoptotic rate and the absence of Akt activation of SMCs versus controls in both treatment groups may imply the potential of a lower restenosis rate, especially after two cycles of supercooling and rewarming. Further in vivo and clinical investigations are needed to confirm results of the...
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PMID: 18503909
PDF is available here.
Abstract
On the basis of a case report the prehospital management of a newborn child with deep accidental hypothermia (22oC) is discussed. The child was found in a garbage can. The continuous resuscitation during the transport into the clinic is done in an incubator and the child survives without neurologic...
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PMID: 18409118
PDF is available here.
Abstract
We have previously shown that cold-induced injury to hepatocytes and liver endothelial cells occurs predominantly via an iron-dependent pathway. However, other groups have reported evidences suggesting that Ca(2+) ions could be involved in the process of cold-induced injury of liver cells. We here a...
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PMID: 18177850
PDF is available here.
Abstract
We employed the principles of fundamental cryobiology to improve the cryopreservation protocol of a C57BL/6 mouse ES cell line by characterizing the membrane permeability characteristics and osmotic tolerance limits. These values were used to predict optimal cooling rates, warming rates, and type of...
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PMID: 18191827
PDF is available here.
Abstract
RT quantifies convective heating by blood prior to RF. Faster RT predicts greater cooling by blood during irrigated RF, a greater power requirement to reach target electrode temperature, and a higher risk of steam pops during fixed-temperature ablation. RT therefore can demonstrate the variation in...
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PMID: 18081763
PDF is available here.
Abstract
A 37-weeks pregnant woman was admitted to the accident and emergency department with hypothermia following possible drug misuse. Although her pulse and blood pressure were normal, her fetus was found to have marked bradycardia. This caused anxiety and quick transfer of the unconscious and still hypo...
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PMID: 18299376
PDF is available here.
Abstract
Survival of hypothermic avalanche victims with cardiac arrest is rare. This report describes full recovery of a 29-year-old backcountry skier completely buried for 100 min at 3.0m (9.8 ft) depth. On extrication he was unconscious, but breathing spontaneously into an air pocket; core body temperature...
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PMID: 17988783
PDF is available here.
Abstract
We report the case of a 11-year-old girl with fulminant myocarditis and cardiogenic shock who received cardiopulmonary resuscitation and extracorporeal membrane oxygenation support. During the induction of hypothermia, her rhythm degenerated into idioventricular rhythm with extremely prolonged QRS d...
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PMID: 17935857
PDF is available here.
Abstract
The combination of hypothermic (32 degrees C) CPB coupled with limited rewarming and prolonged postoperative hypothermia (35 degrees C) decreased POCD after CPB in rats....
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PMID: 18292411
PDF is available here.
Abstract
Hypothermia, a common problem for patients having surgery, adversely affects multiple organ systems and physiologic functions. Research indicates that maintaining normothermia can reduce infection rates, operative blood loss, and length of hospital stay. Often, preventing hypothermia is not a high p...
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PMID: 18262000
PDF is available here.
Abstract
We report here a patient with severe hypothermia (27 degrees C), who was successfully rewarmed by using a novel intravascular rewarming method (in combination with an airways rewarming method) through endotracheal tube.
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PMID: 18180670
PDF is available here.
Abstract
We studied changes in Ca2+ homeostasis in in situ hearts following hypothermia and rewarming. A rat model designed for studies of the intact heart in a non-arrested state during hypothermia and rewarming was used. Rats were core cooled to 15 degrees C, maintained at 15 degrees C for 4h and thereafte...
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PMID: 17983615
PDF is available here.
Abstract
Profound hypothermia is associated with high mortality and morbidity. Optimal outcomes have been reported with invasive extracorporeal warming techniques not readily available in most hospitals. Endovascular warming devices may provide a less invasive alternative. A 68-year-old woman developed profo...
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PMID: 17681640
PDF is available here.
Abstract
Cold-suppressed thermoregulatory reactions and respiration in rats in deep hypothermia (rectal body temperature (25-22 degrees C) were shown to be stimulated by injecting disodium ethylenediaminetetraacetic acid (EDTA) solution into the blood stream of cold rats at a dose of 16.5 mg/100 g (0.0045 mm...
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PMID: 18197391
PDF is available here.
Abstract
The endothelium of porcine aortic segments sustained moderate injury during the cold incubation itself, but major injury during rewarming. The addition of the iron chelator deferoxamine (1 mmol/L) significantly inhibited cold-induced endothelial cell injury irrespective of the solution used for cold...
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PMID: 18164170
PDF is available here.
Abstract
The results show that the warming of intravenous fluids by using the Hotline system prevents decreases in systemic temperatures during OPCAB surgery....
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PMID: 18249333
PDF is available here.