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Sorption Detoxification (5):
Recent article
Sorption Detoxification
Abstract
We examined the dynamics of TNF capture within porous, polymeric sorbent beads used in a cytokine adsorption device. We sought to quantify how perturbation of TNF oligomeric structure accelerates TNF removal within the device. TNF was incubated with 10% DMSO for 24 h, which promoted complete monomer...
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PMID: 21504054
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
We examined the dynamics of TNF capture within porous, polymeric sorbent beads used in a cytokine adsorption device. We sought to quantify how perturbation of TNF oligomeric structure accelerates TNF removal within the device. TNF was incubated with 10% DMSO for 24 h, which promoted complete monomer...
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PMID: 21504054
PDF is available here.
PDF is available here.
Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society (100)1 2011
Abstract
Acute liver failure is a life-threatening condition in the absence of liver transplantation option. The aetiology of liver failure is the most important factor determining the probability of native liver recovery and prognosis of the patient. Extracorporeal liver assist devices like MARS (Molecular A...
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PMID: 21482500
PDF is available here.
PDF is available here.
Abstract
This chapter discusses the characteristics and treatment of acute fluoride toxicity as well as the most common sources of overexposure, the doses that cause acute toxicity, and factors that can influence the clinical outcome. Cases of serious systemic toxicity and fatalities due to a...
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PMID: 21701192
PDF is available here.
PDF is available here.
Abstract
The current study was conducted to evaluate the ability of Egyptian bentonite (EB) and montmorillonite (EM) for the prevention of genotoxicity, histochemical and biochemical changes induced by aflatoxin B(1) (AFB(1)) using the micronucleus (MN) assay, chromosomal aberrations and DNA fragmentation an...
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PMID: 20817254
PDF is available here.
PDF is available here.
Public Health (124)7 2010
Abstract
There has been no proven method thus far to accelerate the clearance of potentially toxic perfluorinated compounds (PFCs) in humans. PFCs are a family of commonly used synthetic compounds with many applications, including repelling oil and stains on furniture, clothing, carpets and food packaging, a...
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PMID: 20621793
PDF is available here.
PDF is available here.
New Zealand Medical Journal (123)1317 2010
Abstract
This pattern of admissions is new to the detoxification unit, and may relate to higher codeine content in the combination product, and marketing strategies. These cases likely represent the severer end of the spectrum of codeine dependency acquired from OTC pharmacy sources. The paucity of evidence...
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PMID: 20657632
PDF is available here.
PDF is available here.
Abstract
In surviving ALF patients, the health-related quality of life after treatment was generally high and comparable to the age- and gender-matched general Finnish population. Compared to the controls, the average cost per QALY was considerably lower in the MARS group (64,732 euros vs 133,858 euros) with...
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PMID: 20458759
PDF is available here.
PDF is available here.
Abstract
We also discuss here the pathophysiological role of PEDF in this devastating disorder....
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PMID: 20236051
PDF is available here.
PDF is available here.
Abstract
One hundred and forty-nine patients with ACLF were included of which 67 (44.9%) were treated with MARS and 82 (55.1%) assigned to the control group. Mean survival was 692 days in MARS-treated patients (33% survival after 3 years) and 453 days in control patients (15% after 3 years, logrank P = 0.022...
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PMID: 19773666
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
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PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
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PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
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PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
|
PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
|
PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
|
PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
|
PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
|
PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
|
PMID: 19817727
PDF is available here.
PDF is available here.
Artificial Organs (34)2 2010
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
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PMID: 19817727
PDF is available here.
PDF is available here.
Abstract
We summarize our experience with a computational, multiscale investigation of this device's hydrodynamic functionality. 3D computational fluid dynamics models were developed for the upper-scale studies. The flow behavior in the sorbent material was either modeled as a homogeneous Darcy's flow (macro...
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PMID: 20519899
PDF is available here.
PDF is available here.
Abstract
The article providing in-depth analysis of pathogenesis of obstructive jaundice shows that this disease is manifest not only as changes at the hepatic level (cholestasis, cholehemia, cholangitis, cholangio- and lymphovenous shunts, hepatic encephalopathy) but also as marked dysbiotic...
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PMID: 21400719
PDF is available here.
PDF is available here.
Abstract
Artificial Organs (34)2 2009
Abstract
We evaluated the influence of FPSA on plasma amino acid patterns in patients with liver failure and hepatic encephalopathy. We studied nine patients with acute-on-chronic liver failure, hepatic encephalopathy, and concomitant renal failure. A single session of FPSA therapy for 5 +/- 1 h was performe...
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PMID: 19817727
PDF is available here.
PDF is available here.
Abstract
The study included 113 patients with acute liver failure (ALF), 62 with acute-on-chronic liver failure (AOCLF), 11 with graft failure (GF), and six with miscellaneous liver failure. LTX was performed for 29% of patients with ALF, 18% with AOCLF and 55% with GF. The overall 1-year survival rate was 7...
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PMID: 19554655
PDF is available here.
PDF is available here.
Klinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukrainy, Naukove tovarystvo khirurhiv Ukrainy ()5 2009
Abstract
The work objective is the results of complex treatment improvement in patients with diabetic foot syndrome. The work is based on the results of complex treatment analysis data in 32 patients suffering diabetes mellitus, complicated by diabetic foot syndrome. There was proved the efficacy of applicat...
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PMID: 19957747
PDF is available here.
PDF is available here.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology (17)5 2009
Abstract
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology (17)5 2009
Abstract
Abstract
We identified a large number of proteins removed by extracorporeal liver support system. A selective adsorption was demonstrated in a subset of proteins depending on the type of adsorber and proteins' characteristics....
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PMID: 19265403
PDF is available here.
PDF is available here.
Abstract
Abstract
Molecular recognition-based Al(3+)-imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-glutamic acid) (PHEMAGA-Al(3+)) beads were prepared to be used in selective removal of Al(3+) out of human plasma overdosed with Al(3+) cations. The PHEMAGA-Al(3+) beads were synthesized by suspension polyme...
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PMID: 19520010
PDF is available here.
PDF is available here.
Terapevticheskii arkhiv (81)12 2009
Abstract
There was a significant relationship of the levels of Ab to Cat and XO to the activity of SLE. It was shown that Ab to Cat and XO could affect the functional activity of serum enzymes. The level of Ab to CL in patients with SLE was found to depend on two parameters - the intensity of the disease and...
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PMID: 20481049
PDF is available here.
PDF is available here.
Abstract
Comprehensive analysis of criteria for the severity of clinical conditions in patients with craniocerebral injuries included characteristics of cerebrospinal fluid and lesions of hematoencephalic barrier (HEB). The study revealed the relationship between clinico-neurological conditions of the patien...
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PMID: 20000102
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
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PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
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PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Seminars In Dialysis (22)6 2009
Abstract
To regenerate dialysate in hemodialysis for kidney failure, it is necessary to remove all uremic toxins, avoid excessive removal of various electrolytes, and supply beneficial components such as bicarbonate. Surprisingly, a simple collection of components can accomplish this task ver...
|
PMID: 20017831
PDF is available here.
PDF is available here.
Abstract
A total of 38 women of reproductive age (from 20 to 45 years) with chronic inflammatory gynecological diseases including 7 with primary and 9 with secondary infertility were examined by standard clinical, instrumental, and laboratory methods. In addition, variations of such important characteristics...
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PMID: 19284115
PDF is available here.
PDF is available here.
Abstract
Analysis of experimental data about the quantitative and qualitative chemical make-up of air in the orbital station Mir and International space station (ISS) showed a permanent presence of silicon. The main source of silicon contaminants seems to be a variety of polymethyl siloxane liquids and silox...
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PMID: 19621808
PDF is available here.
PDF is available here.
Abstract
This paper presents the results of treating 8 patients with acute liver failure, by using the separation and adsorption of fractional plasma (Prometheus technology). Twenty-five procedures lasting 5-6 hours were performed. Anticoagulation with heparin was made under guidance of coagulogram parameter...
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PMID: 19514440
PDF is available here.
PDF is available here.
Abstract
Uranium(VI) sorption by two highly uranium-resistant air-borne fungi in a low-pH medium was measured by means of gamma spectrometry. Growth kinetics and stoichiometry of the two fungal species were also studied. Results show acceptable growth rates in synthetic medium with glucose and ammonia as car...
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PMID: 19149355
PDF is available here.
PDF is available here.
Metabolic Brain Disease (23)4 2008
Abstract
According to one popular theory, hepatic encephalopathy (HE) is partly caused by an imbalance in plasma amino acid levels. The Fischer's ratio between branched chain amino acids (BCAAs) and aromatic amino acids (AAAs) correlates with the degree of HE; the lower Fischer's ratio, the higher the grade...
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PMID: 18773287
PDF is available here.
PDF is available here.
Abstract
We report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus....
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PMID: 19030215
PDF is available here.
PDF is available here.
Chinese Medical Journal (121)21 2008
Abstract
MARS continues to be the most favorable extracorporeal treatment for liver support therapy in China for a wide range of conditions, including the majority of hepatitis B related liver failure conditions. The appropriate application of MARS for the right indications and stage of hepatic failure, as w...
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PMID: 19080184
PDF is available here.
PDF is available here.
Abstract
The molecular adsorbent recycling system (MARS) is now widely used in the treatment of patients with hepatic failure (HF). A great deal of interest has been directed toward its effect on clinical outcome, whereas its depurative capacity also needs attention. Bilirubin, a tightly albumin-bound toxin...
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PMID: 19009505
PDF is available here.
PDF is available here.
Nursing Management (39)9 2008
Abstract
Firm up on the facts and considerations associated with acetaminophen toxicity.
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PMID: 18779692
PDF is available here.
PDF is available here.
Abstract
Artificial Organs (32)7 2008
Abstract
New detoxification modes of treatment for liver failure that use solid adsorbents to remove toxins bound to albumin in the patient bloodstream are entering clinical evaluations, frequently in head-to-head competition. While generally effective in reducing toxin concentration beyond that obtainable b...
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PMID: 18638303
PDF is available here.
PDF is available here.
Abstract
The 56 treated AoCLF patients underwent 278 treatment sessions; 41 out of 191 procedures with MARS and 16 out of 87 procedures with prometheus, which was also applied in two cases in PNF and four in secondary liver insufficiency. The results showed that both systems accomplished a good purification...
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PMID: 18555140
PDF is available here.
PDF is available here.