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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Antineoplastic Protocols (1):
Recent article
Antineoplastic Protocols
Abstract
We discussed the usefulness and feasibility of current chemotherapy protocols for urological cancers including renal cell carcinoma, urothelial cancer, prostate cancer and testicular cancer. (1) Renal cell carcinoma : Although molecular targeted therapy is now becoming a standard therapy for metasta...
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PMID: 21586888
PDF is available here.
PDF is available here.
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Abstract
Leukemia & Lymphoma (51)4 2010
Abstract
Leukemia & Lymphoma (51)4 2010
Abstract
The diagnostic value of JAK2 mutational analysis in myeloproliferative neoplasms (MPN) is now well established and endorsed by the World Health Organization classification system for hematologic malignancies. The current review is focused on the prognostic impact and therapeutic relevance of JAK2 an...
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PMID: 20214447
PDF is available here.
PDF is available here.
Abstract
Anti-Cancer Drugs (21)3 2010
Abstract
We found that gemcitabine alone can activate nuclear factor kappaB (NF-kappaB) in osteosarcoma, suggesting the potential mechanism of acquired chemoresistance. In contrast, genistein reversed the cancer's resistance to gemcitabine through the downregulation of NF-kappaB activity and the suppression...
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PMID: 20038829
PDF is available here.
PDF is available here.
Abstract
As a safe way to manage cancer chemotherapy, a regimen registration system of chemotherapies was started in our hospital in April of 2007. Only chemotherapies registered in the regimen system can be conducted. Beginning in July of 2007, to assure safer chemotherapy, a standard clinical value of labo...
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PMID: 20154504
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
European Spine Journal (19)2 2010
Abstract
Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the cl...
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PMID: 20039084
PDF is available here.
PDF is available here.
Abstract
Inherited defects in components of the nonhomologous end-joining DNA repair mechanism produce a T-B-NK+ severe combined immunodeficiency disease (SCID) characterized by heightened sensitivity to ionizing radiation. Patients with the radiosensitive form of SCID may also have increased short- and long...
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PMID: 20113890
PDF is available here.
PDF is available here.
Acta Cytologica (54)4 2010
Primary serous peritoneal carcinoma presenting first on a routine papanicolaou smear: a case report.
Abstract
BACKGROUND: Primary peritoneal carcinoma (PPC) is a relatively uncommon malignancy, and its presentation is similar to that of advanced ovarian serous carcinoma. There have been afew case reports in which the malignant cells from PPC were discovered from routine Papanicolaou (Pap) smears. CASE: In 2...
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PMID: 20715668
PDF is available here.
PDF is available here.
Abstract
The influence of the number of apheresis-stimulation-infusion(s) cycles, and the time in culture before the infusion (one vs. two weeks), on the generation of tumor antigen-specific cytotoxic T-lymphocytes (CTL) was investigated in a phase I/II clinical adoptive immunotherapy trial. Two previously t...
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PMID: 20653425
PDF is available here.
PDF is available here.
Abstract
We develop an optimization algorithm to inversely determine the optimum heating patterns induced by multiple nanoparticle injections in tumor models with irregular geometries. The injection site locations, thermal properties of tumor and tissue, and local blood perfusion rates are used as inputs to...
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PMID: 19670098
PDF is available here.
PDF is available here.
Stomatologiia (88)3 2009
Abstract
Urgent need in methodology of information estimation for true clinical decision taking gave powerful impulse for evidence based medicine concept development that appeared at the end of 80th years. Proved efficacy and safety, optimal correlation of the indices were the stages of the methods and means...
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PMID: 19692943
PDF is available here.
PDF is available here.
Abstract
Obesity is a common complication of treatment for some childhood cancers, particularly acute lymphoblastic leukaemia (ALL) and craniopharyngioma. Evidence-based guidance is available for the general paediatric population on the diagnosis, aetiology, consequences, prevention and treatment of obesity,...
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PMID: 19293603
PDF is available here.
PDF is available here.
Abstract
We provide a comprehensive appraisal of the way in which oncogenes and tumour suppressor genes regulate autophagy. In addition, we address the current evidence from human cancer and animal models that has aided our understanding of the role of autophagy in tumour progression. Finally, the potential...
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PMID: 19951459
PDF is available here.
PDF is available here.
Human Reproduction (23)10 2008
Abstract
These data indicate a high awareness of the potential adverse effects of therapy on fertility among UK paediatric oncologists. High referral rates for older boys indicate that current guidelines are followed, but there is a need for fertility preservation techniques for girls and younger boys....
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PMID: 18614615
PDF is available here.
PDF is available here.
Abstract
The significance of histological diagnosis was retrospectively investigated in the treatment of 79 consecutive patients with pineal region tumours. Histological diagnoses were consistent with clinical diagnoses in 38 out of 39 patients with germ cell tumours and in all eight patients with non-germ c...
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PMID: 18617412
PDF is available here.
PDF is available here.
American Journal of Health-System Pharmacy (65)11 Suppl 4 2008
Abstract
PURPOSE: The results of clinical trials that led to modern first- and second-line chemotherapeutic regimens for metastatic colorectal cancer, including studies of recently introduced monoclonal antibody products that target vascular endothelial growth factor (VEGF) and epidermal growth factor recept...
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PMID: 18499885
PDF is available here.
PDF is available here.
Abstract
Accurate anatomical localization of functional abnormalities obtained with the use of positron emission tomography (PET) is known to be problematic. Although tracers such as (18)F-fluorodeoxyglucose ((18)F-FDG) visualize certain normal anatomical structures, the spatial resolution is generally inade...
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PMID: 18396176
PDF is available here.
PDF is available here.
Abstract
Concurrent and adjuvant TMZ was associated with improved survival compared to adjuvant TMZ alone, highlighting the potentiation of radiation effect by temozolomide in the clinical setting....
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PMID: 18231723
PDF is available here.
PDF is available here.
Abstract
The role of the pathologist has been fundamental in the progress of the treatment of paediatric renal tumours. There are different philosophies in the treatment of these tumours, and there have been many recent advances in the areas of chemotherapy, identification of new entities, prognostic histolo...
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PMID: 18203043
PDF is available here.
PDF is available here.
Abstract
I of this two part article. Part II reviews the preclinical tests and shelf-life testing that are required using drug eluting stents and drug eluting beads as examples. Regulatory considerations and ways to simplify development are also examined....
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PMID: 18557409
PDF is available here.
PDF is available here.
Journal of Immunotherapy (31)9 2008
Abstract
We used VSV-G pseudotype third generation lentiviral vectors harboring specific antitumor T-cell receptor (TCR) to establish clinical-scale lentiviral transduction of peripheral blood lymphocyte (PBL). Spinoculation (1000g, 32 degrees C for 2 h) in the presence of protamine sulfate represents the mo...
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PMID: 18833004
PDF is available here.
PDF is available here.
Abstract
39% of patients (95% CI, 32% - 48%) thought cancer treatment strengthened bones or did not know, and 39% (95% CI, 32% - 48%) either answered that osteoporosis almost never occurred in men or did not know. The mean correct score on the modified Osteoporosis Knowledge Assessment Tool was 6.7 (95% CI,...
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PMID: 18457782
PDF is available here.
PDF is available here.
Paediatric Drugs (10)2 2008
Abstract
The Ewing sarcoma family of tumors (ESFT) is one of the most common groups of malignancies arising in children, adolescents, and young adults up to approximately 25 years of age. It comprises Ewing sarcoma arising from bone and extraosseous Ewing sarcoma arising from soft tissues (which includes per...
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PMID: 18345719
PDF is available here.
PDF is available here.
BMC Cancer (8)1 2008
Abstract
Concerning the parameters nodal involvement, lymphovascular invasion, extracapsular spread and extension of the irradiated region the three treatment groups were significantly imbalanced. The other parameters, e.g. age, pathological tumor stage, grading and receptor status were homogeneously distrib...
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PMID: 18433485
PDF is available here.
PDF is available here.
Medical Dosimetry (33)3 2008
Abstract
We confirm the feasibility of intensity modulated radiotherapy (IMRT) to include treatment of the pelvic nodes (PN) while escalating the dose to the prostate. Data were obtained from 35 consecutive patients with prostate cancer with > or =15% risk of PN involvement. Patients received an initial boos...
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PMID: 18674682
PDF is available here.
PDF is available here.
Medical Dosimetry (33)3 2008
Abstract
The influence of Pro-Qura-generated plans vs. community-generated plans on postprostate brachytherapy dosimetric quality was compared. In the Pro-Qura database, 2933 postplans were evaluated from 57 institutions. A total of 1803 plans were generated by Pro-Qura and 1130 by community institutions. Io...
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PMID: 18674685
PDF is available here.
PDF is available here.
Medical Dosimetry (33)3 2008
Abstract
We found that setting rotational tolerances will depend on which Arm of the protocol the patient is, and how well the initial plan meets the protocol objectives. In general, we conclude that for rotations about the AP axis, no tolerance level is required; however, cases presenting extreme rotations...
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PMID: 18674684
PDF is available here.
PDF is available here.
Medical Dosimetry (33)3 2008
Abstract
The aim of this study was to develop a technique for axillary radiotherapy that minimizes the risk of radiation-induced damage to the surrounding normal tissue (i.e., arm, shoulder, lung, esophagus, and spinal cord) while keeping the risk of a nodal recurrence to a minimum. A planning study was perf...
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PMID: 18674683
PDF is available here.
PDF is available here.
Abstract
We describe a case of primary duodenal MALT lymphoma that was resistant to Helicobacter pylon (H. pylori) eradication and regressed after chemotherapy with cyclophosphamide, vincristine, and prednisolone (CVP). A 71-year-old woman was referred to our department because of epigastric pain and dyspeps...
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PMID: 18309692
PDF is available here.
PDF is available here.
Abstract
Multiple myeloma must be distinguished from monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and several other closely related plasma-cell disorders. In recent years, new systems have emerged for diagnosis, staging, and risk stratification of myeloma. The...
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PMID: 18070712
PDF is available here.
PDF is available here.
Hawaii medical journal (66)10 2007
Abstract
Hepato-gastroenterology (54)76 2007
Abstract
The DPD activity in the tumor may be a useful indicator for selecting patients likely respond to 5'-DFUR together with MMC as adjuvant chemotherapy. If tumor DPD is high, we had better select a different anticancer drug....
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PMID: 17629045
PDF is available here.
PDF is available here.
Abstract
Abstract
We succeeded in reaching consensus throughout The Netherlands on a protocol to screen cancer survivors on late cancer treatment effects. This protocol is now in use by all Dutch outpatient clinics and warrants that the screening of cancer survivors is consistent across The Netherlands. The screening...
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PMID: 16533618
PDF is available here.
PDF is available here.
Oral Oncology (43)3 2007
Abstract
We created a database of those genes newly expressed at 2 weeks and evaluated their potential significance relative to toxicity, by canonical pathway analysis, compilation of regional networks around focus genes, and development of a model globalizing the individual functional networks. There was st...
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PMID: 16920386
PDF is available here.
PDF is available here.
Abstract
We have designed a typical right oropharynx target volume in an anthropomorphic head and neck phantom. Three different treatment techniques have been used to optimally treat this target, including bilateral static fields, eight-field IMRT and helical tomotherapy. The phantom was immobilized in a sta...
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PMID: 17264375
PDF is available here.
PDF is available here.
Abstract
The five-year event-free survival of nearly 80% in childhood acute lymphoblastic leukemia (ALL) achieved in the 1990 s attested to the effectiveness of risk-directed therapy developed through well-designed clinical trials by 4 groups in clinical study, containing CCLSG, TCCSG, KYCCSG and JACLS. Japa...
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PMID: 17301519
PDF is available here.
PDF is available here.
Abstract
Ewing sarcoma is the second most frequent primary bone cancer affecting children or young adults. Advances in molecular biology have revealed common chromosomal translocations such as EWS-FLI 1 among Ewing sarcoma and related diseases such as primitive neuroectodermal tumor (PNET), so these are cons...
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PMID: 17301523
PDF is available here.
PDF is available here.
Abstract
The annual incident rate of pediatric acute myeloid leukemia (AML) is now 10 per million in Japan, against 5 to 9 per million in the USA and Europe. Overall long-term survival has now been achieved for more than 50% of pediatric patients with AML in the USA and in Europe. The prognostic factors of p...
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PMID: 17301520
PDF is available here.
PDF is available here.
Abstract
Pediatric Neurosurgery (43)2 2007
Abstract
Post-treatment, 3 group 1 and 12 group 2 patients manifested residual tumors. The pathological diagnosis in group 1 patients was mature teratoma, pineal cyst, and fibrous tissue with calcification; in group 2 it was yolk sac tumor (n = 1), immature teratoma (n = 3), mature teratoma (n = 4), and necr...
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PMID: 17337917
PDF is available here.
PDF is available here.
BMC Cancer (7)1 2007
Abstract
BACKGROUND: Adjuvant chemotherapy has been proven to be beneficial for patients with early stage non-small cell lung cancer. However, toxicity and insufficient dose delivery have been critical issues with the chemotherapy used. Doublet regimens with pemetrexed, a multi-target folate inhibitor, and p...
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PMID: 17488518
PDF is available here.
PDF is available here.
Value in Health (10)5 2007
Abstract
Switching postmenopausal early-stage breast cancer patients to exemestane after 2 to 3 years of tamoxifen appears to be a cost-effective treatment strategy versus completing a 5-year course of tamoxifen....
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PMID: 17888101
PDF is available here.
PDF is available here.
Voprosy onkologii (53)1 2007
Abstract
Voprosy onkologii (53)1 2007
Abstract
Voprosy onkologii (53)1 2007
Abstract
A group of 87 patients with primary Hodgkin's disease involving the lungs and/or pleura was selected by means of radiological screening. Specific changes in the lungs and/or pleura appeared in the younger cohort 5.7 months (1-24 months) after first signs development, which presented mainly as nodula...
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PMID: 17649741
PDF is available here.
PDF is available here.