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Chemotherapy, Adjuvant (0):
Recent article
Chemotherapy, Adjuvant
Abstract
To ascertain if breast cancer subtypes had prognostic effect on breast cancer specific survival, distant metastases and local relapse rates in women affected by early stage breast cancer.
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PMID: 21824742
PDF is available here.
PDF is available here.
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Abstract
To evaluate the feasability of immediate breast reconstruction (IBR) following mastectomy after neoadjuvant chemotherapy (NACT) and radiation therapy (RT) for operable invasive breast cancer (OIBC), in terms of incidence of local complications, locoregional control and survival.
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PMID: 21843920
PDF is available here.
PDF is available here.
Abstract
To describe surgical outcomes in patients with HER2-positive locally advanced (LABC) or inflammatory breast cancer (IBC) participating in the NeOAdjuvant Herceptin (NOAH) study (ISRCTN86043495).
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PMID: 21843921
PDF is available here.
PDF is available here.
New England Journal of Medicine (365)14 2011
Abstract
We wanted to evaluate the efficacy and safety of a new nonanthracycline regimen with trastuzumab.
We randomly assigned 3222 women with HER2-positive early-stage breast cancer to receive doxorubicin and cyclophosphamide followed by docetaxel every 3 weeks (AC-T), the same regimen plus...
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PMID: 21991949
PDF is available here.
PDF is available here.
Medicinski pregled (64)3-4 2011
Abstract
The aim of this study was to show whether immunotherapy should be administered in patients with renal cell carcinoma after radical nephrectomy in N0 and N1 stage of disease. The research was conducted in 60 patients with renal adenocarcinoma after radical nephrectomy. The study group included two sub...
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PMID: 21905595
PDF is available here.
PDF is available here.
Abstract
We report that functional hemodynamic and metabolic information acquired using a noninvasive optical imaging method on the first day after neoadjuvant chemotherapy treatment can discriminate nonresponding from responding patients. Diffuse optical spectroscopic imaging was used to measure absolute co...
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PMID: 21852577
PDF is available here.
PDF is available here.
Abstract
Two-thirds of women who are newly diagnosed with invasive epithelial ovarian cancer present with stage III or IV disease.The preferred initial treatment has traditionally consisted of primary surgical debulking followed by platinum-based chemotherapy. However, recent data suggesting...
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PMID: 22010391
PDF is available here.
PDF is available here.
Abstract
We screened 240 sera from 64 patients with primary breast cancer. This unique longitudinal sample material was collected from each patient between 0 and 36 mo after the primary operation. The velocity for each serum protein was determined by comparing the samples collected at the primary operation a...
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PMID: 21844363
PDF is available here.
PDF is available here.
Abstract
We report our technique that uses adjunctive intraoperative injection of sodium morrhuate, 5%, under direct visualization into lymphangioma channels prior to excision. We believe that in the hands of experienced orbital surgeons, and with appropriate preoperative evaluation and careful surgical tech...
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PMID: 21825192
PDF is available here.
PDF is available here.
Abstract
Two phase 3 studies evaluated the efficacy and safety of rosiglitazone (RSG), a type 2 diabetes treatment, in an extended release (RSG XR) form as adjunctive therapy to ongoing acetylcholine esterase inhibitor (AChEI) treatment in AD (REFLECT-2, adjunctive to donepezil; REFLECT-3, to...
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PMID: 21592048
PDF is available here.
PDF is available here.
Abstract
We reported a 34 years old caucasian woman with acute renal failure and hypercalcemia as onset of splenic lymphoma in absence of abnormal levels of serum vitamin D and PTHrP. Because of dramatic recovery of renal function and hypercalcemia after splenectomy, we can speculate that main mechanism of h...
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PMID: 21780556
PDF is available here.
PDF is available here.
Abstract
Alloplastic breast reconstruction necessitating postmastectomy radiotherapy (PMRT) is at increased risk for complications such as capsular contracture, infection, extrusion, and poor cosmetic results. However, often the indication for PMRT is not decided until a permanent histological examination wit...
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PMID: 21780554
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
To evaluate the role of enbloc resection on the oncological outcome of patients with Ewing's sarcoma of the mobile spine treated with systemic multiagent chemotherapy combined with radiation therapy. While the role of chemotherapy and radiation therapy is well known and accepted in the treatment of E...
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PMID: 21780553
PDF is available here.
PDF is available here.
Abstract
This multicenter, open-label, single-arm, Phase II study assessed the efficacy of a neoadjuvant chemotherapy with docetaxel (75 mg/m(2) q3w) followed by 5-fluorouracil 500 mg/m(2), epirubicin 100 mg/m(2) and cyclophosphamide 500 mg/m(2) q3w in patients with early-stage breast cancer.
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PMID: 21719750
PDF is available here.
PDF is available here.
Abstract
We evaluated our long-term experience with chemoradiation therapy (CRT) for bladder preservation....
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PMID: 21616918
PDF is available here.
PDF is available here.
Presse Medicale (40)11 2011
Abstract
Twenty cases were collected. The mean age was 61.25 years. Skin invasion by tumor was found in all patients, and it was the reason for consultation. It was a cutaneous involvement at the nipple and areola (17 cases) and at the periareolar skin (three cases). The clinical appearance of skin involveme...
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PMID: 21684107
PDF is available here.
PDF is available here.
Oral Oncology (47)7 2011
Abstract
To retrospectively review the diagnosis and treatment outcomes of 21 diagnosed with synovial sarcoma (SS) extending to skull base region and identify prognostic factors for local recurrence and distant metastasis. The clinical and pathological records of 21 synovial sarcoma cases inv...
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PMID: 21641853
PDF is available here.
PDF is available here.
Abstract
: Daily chest radiation schedules can be cumbersome for some patients and could also delay the administration of higher, systemic doses of chemotherapy.
: Thirty-six patients with advanced non-small cell lung cancer (stages IIIB and IV) were treated using a once weekl...
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PMID: 21613934
PDF is available here.
PDF is available here.
Abstract
Male breast cancer is a rare entity. Statistics suggest the female:male ratio is100:1. Male breast cancer is most frequent in elderly patients, but it can occur at any age. The mean age of the onset of the disease is 10 years later in males compared to female patients. Here, the authors review the pr...
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PMID: 21672681
PDF is available here.
PDF is available here.
Minerva ginecologica (63)3 2011
Abstract
Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, but based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy....
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PMID: 21654611
PDF is available here.
PDF is available here.
Progrès en Urologie (21)6 2011
Abstract
Bladder cancer represents for man the second genitourinary cancer after prostate cancer. Urothelial carcinoma is the most predominant histological type. In up to 70% of the cases, the diagnosis of bladder cancer is performed at early stages (Ta-T1). In this situation, the treatment of the disease is...
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PMID: 21620296
PDF is available here.
PDF is available here.
Abstract
The ideal treatment of patients with "borderline resectable pancreatic tumors (BRTs)" needs to be established. Current protocols advise neoadjuvant chemo(radio)therapy, although some patients may appear to have BRT on preoperative imaging and a complete resection may be achieved with...
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PMID: 21669578
PDF is available here.
PDF is available here.
Abstract
We review criteria for transplantation, the types, indications, and role of locoregional therapy in treating the cancer and in downstaging for possible later transplantation. We also summarize the contribution of immunosuppression and adjuvant chemotherapy in the management and prevention of HCC rec...
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PMID: 21669564
PDF is available here.
PDF is available here.
Abstract
The management of metastatic disease in pancreatic endocrine tumors (PETs) demands a multidisciplinary approach and the cooperation of several medical specialties. The role of surgery is critical, even when a radical excision cannot always be achieved.
A PubMed search...
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PMID: 21669565
PDF is available here.
PDF is available here.
Abstract
The indication of neoadjuvant chemotherapy has been recently extended; it is now applied not only in locally advanced breast cancer but in primarily resecable tumours as well, in order to promote breast conservation. Based on recent clinical results, the reconsideration of traditional lymph node diss...
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PMID: 21655472
PDF is available here.
PDF is available here.
New England Journal of Medicine (364)21 2011
Abstract
Abstract
We sought to determine the safety and utility of restaging mediastinoscopy before surgical resection....
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PMID: 21616475
PDF is available here.
PDF is available here.
Abstract
Surgical intervention after chemoradiation for locoregionally advanced non-small cell lung cancer (NSCLC) is controversial. This study evaluated patient survival after neoadjuvant chemoradiation and anatomic pulmonary resections for locoregionally advanced NSCLC.
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PMID: 21620372
PDF is available here.
PDF is available here.
Abstract
This study was designed to assess the treatment of patients in whom a second primary lung cancer developed after the resection of primary lung cancer.
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PMID: 21600562
PDF is available here.
PDF is available here.
Annales de Dermatologie et de Vénéréologie (138)5 Suppl 1 2011
Abstract
Abstract
Gene expression analysis is a valuable tool for determining the risk of disease recurrence and overall survival of an individual patient with breast cancer. The purpose of this study was to create and validate a robust prognostic algorithm and implement it within an online analysis e...
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PMID: 21458382
PDF is available here.
PDF is available here.
Journal of Immunotherapy (34)4 2011
Abstract
We evaluated HRQoL using the European Organization for Research and Treatment of Cancer Quality of Life Core 30 questionnaire at baseline and after 3, 6, and 12 months of IFN-α treatment in 282 patients. Nine of 15 subscales showed significant poorer results after 3 months of adjuvant IFN treatment...
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PMID: 21499123
PDF is available here.
PDF is available here.
Abstract
To review the Stanford University experience with total skin electron-beam therapy (TSEBT) of 30 Gy or greater as monotherapy in patients with mycosis fungoides (MF) and compare with subgroups receiving adjuvant nitrogen mustard (HN2), and further update our experience with repeated courses of TSEBT....
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PMID: 21576575
PDF is available here.
PDF is available here.
Clinical Cancer Research (17)12 2011
Abstract
The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, irinotecan and temozolomide for the treatment of newly diagnosed glioblastoma has moderate toxicity and may improve efficacy compared with historical controls. The results from phase III trials are re...
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PMID: 21531816
PDF is available here.
PDF is available here.
Abstract
Neoadjuvant therapy has been used to improve survival in operable pancreatic cancer. The authors' objective was to compare long-term outcomes in patients receiving neoadjuvant versus adjuvant therapy for resectable pancreatic adenocarcinoma.
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PMID: 21523715
PDF is available here.
PDF is available here.
Orvosi Hetilap (152)18 2011
Abstract
Exploration of construction, function and interaction of human growth hormone and growth hormone receptor in details resulted in the innovation of the new growth hormone receptor antagonist, pegvisomant. Pegvisomant with different mechanism of action extended the tools of medical management of acrome...
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PMID: 21498159
PDF is available here.
PDF is available here.
Abstract
Abstract
This article discusses data from 3 randomized phase 3 trials, supporting a role for surgery in glioblastoma.
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PMID: 21479583
PDF is available here.
PDF is available here.
Abstract
Estrogen receptor (ER) and progesterone receptor (PR) are important prognostic and predictive biomarkers in breast cancer. Patients with tumors positive for either receptor are generally considered hormone receptor-positive for treatment decisions. However, some data suggest that patients with ER(+)...
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PMID: 21472707
PDF is available here.
PDF is available here.
Abstract
A 48-year-old woman presented with a 15-cm diameter tumor in her left breast with fixation to the chest wall and palpable axillary lymph nodes. Pathology study showed pure-type mucinous carcinoma. Pretreatment staging investigations showed multiple lung metastases, which resulted in...
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PMID: 21519998
PDF is available here.
PDF is available here.
Abstract
We performed Shouldice repair for bilateral inguinal hernias to prevent radiation injury to the fixed small intestines. Later our patient received 55 Gy of radiation therapy and two series of Carboplatin chemotherapy. Following radio-chemotherapy our patient did not developed radiation enteritis. In...
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PMID: 21504858
PDF is available here.
PDF is available here.
Abstract
To examine the safety of sorafenib combined with standard adjuvant treatment in patients with node-positive or otherwise high-risk breast cancer.
Eligibility: mastectomy/breast-conserving surgery; axillary node assessment for stage I/II/IIIA/IIIC (T1-3, N3a only) brea...
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PMID: 21558987
PDF is available here.
PDF is available here.
Abstract
We evaluated the outcomes of these therapeutic options in the treatment of FIGO stage III and IV ovarian cancers with intraperitoneal dissemination....
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PMID: 21498987
PDF is available here.
PDF is available here.
Abstract
To investigate the influence of comorbidities on treatment modalities of colorectal cancer according to the age of patients and French recommendations.
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PMID: 21438864
PDF is available here.
PDF is available here.
Presse Medicale (40)4 Pt 1 2011
Abstract
The objectives of perioperative treatments in non-small cell lung cancer (NSCLC) are to reduce the risk of recurrence, by the early destruction of micrometastases. Data from the literature have been used to precise their indications and modalities. However, for each patient, the decision of a periope...
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PMID: 21420825
PDF is available here.
PDF is available here.
Abstract
We suggest that contralateral level IV dissection is not necessary in patients with cN0 hypopharyngeal squamous cell carcinoma (HPSCC). Objectives: Elective treatment of neck nodes is very important in the management of cN0 HPSCC. A selective neck dissection neck level II to IV (SND II-IV) is widely...
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PMID: 21395474
PDF is available here.
PDF is available here.
Abstract
Presse Medicale (40)4 Pt 1 2011
Abstract
Bronchioloalveolar carcinoma (BAC) is a primary pulmonary adenocarcinoma (ADC) developped from the terminal respiratory unit. Its restrictive definition adopted by the 1999 WHO pathological classification needs a complete tumor resection to exclude any signs of histological invasion. Although IIIB-IV...
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PMID: 21419590
PDF is available here.
PDF is available here.
Abstract
The current study was conducted to compare simultaneously obtained bone marrow (BM) cytogenetics (CTG), peripheral blood (PB) and BM fluorescence in situ hybridization (FISH), and quantitative real-time polymerase chain reaction (Q-PCR) for BCR-ABL1 in monitoring response to treatment with tyrosine k...
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PMID: 21381013
PDF is available here.
PDF is available here.
Abstract
Abstract
Serial monitoring of changes in AFP levels during the treatment, especially perioperative changes, may help identify favorable and poor responders to chemotherapy. Alternative treatment, such as liver transplantation, should be considered for poor responders. Pediatr Blood Cancer © 2011 Wiley-Liss,...
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PMID: 21370433
PDF is available here.
PDF is available here.
Magyar Onkológia (55)1 2011
Abstract
In several large adjuvant clinical trials it has been demonstrated that substitution (eventually addition) of aromatase inhibitors (AIs) provides an improved outcome of endocrine-sensitive breast cancer over tamoxifen alone. Nevertheless, arthralgia induced by the AIs is one of the most frequent side...
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PMID: 21617789
PDF is available here.
PDF is available here.
Abstract
We report a case of a 29-year-old woman patient with primary breast carcinoma and high grade astrocytoma subsequently developed. The woman was treated by mastectomy and 20 months post-diagnosis of the cancer she exhibited a transient facial paralysis. Magnetic resonance imaging (MRI) revealed two cr...
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PMID: 21528782
PDF is available here.
PDF is available here.
Progrès en Urologie (21 Suppl 2) 2011
Abstract
We can sometimes discuss, at an individual level, a bladder conservative strategy with an intensive surveillance....
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PMID: 21397826
PDF is available here.
PDF is available here.
Abstract
Pancreatic endocrine tumors (PETs) are characterized by the presence of hormone syndromes. Reports focusing on calcitonin-secreting PET (CTsPETs) are very rare. This study aimed to define a CTsPET-associated syndrome in regard to chemical, anatomical, and developmental aspects.
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PMID: 21178652
PDF is available here.
PDF is available here.
Clinical Cancer Research (17)8 2011
Abstract
Changes in tumor metabolism from positron emission tomography (PET) in locally advanced breast cancer (LABC) patients treated with neoadjuvant chemotherapy (NC) are predictive of pathologic response. Serial dynamic [(18)F]-FDG (fluorodeoxyglucose) PET scans were used to compare kinetic parameters wit...
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PMID: 21364034
PDF is available here.
PDF is available here.
Abstract
We report the outcome and safety of a risk-adapted strategy by the Hellenic Cooperative Oncology Group....
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PMID: 19362863
PDF is available here.
PDF is available here.
Abstract
Signet ring cell carcinoma of the ampulla of Vater is a rare entity and less than 20 cases have been described in the literature. We report the cases of two patients with this disease and provide a literature review of previous studies.
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PMID: 21376425
PDF is available here.
PDF is available here.