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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Lymphoid Tissue (8):
Recent article
Lymphoid Tissue
Nature Immunology (12)7 2011
Abstract
We show that iBALT formed in mouse lungs as a consequence of pulmonary inflammation during the neonatal period. Although we found CD4(+)CD3(-) lymphoid tissue-inducer cells (LTi cells) in neonatal lungs, particularly after inflammation, iBALT was formed in mice that lacked LTi cells. Instead, we fou...
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PMID: 21666689
PDF is available here.
PDF is available here.
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Nature Immunology (12)4 2011
Abstract
We show that in contrast to T(H)17 cells, both types of RORγt+ ILCs constitutively produced most of the intestinal IL-22 and that the symbiotic microbiota repressed this function through epithelial expression of IL-25. This function was greater in the absence of adaptive immunity and was fully rest...
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PMID: 21336274
PDF is available here.
PDF is available here.
Abstract
We here present genetic data showing that concomitant ablation of MMP9 (gelatinase B) and the serine protease plasmin results in lethal inflammatory mass lesions in the colon. These lesions possessed several histological attributes that are characteristic of mucosal prolapse seen in humans, and they...
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PMID: 21123624
PDF is available here.
PDF is available here.
Abstract
Examine lymphatic malformation lymphoid aggregates for the expression of tertiary lymphoid organ markers. Determine how lymphoid aggregate density relates to lymphatic malformation clinical features.
Retrospective cohort study. Tissue and clinical data were reviewed f...
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PMID: 21688977
PDF is available here.
PDF is available here.
Abstract
We recently found, by immunohistochemical staining, that follicular helper T cells associated with neoplastic L and H cells in nodular lymphocyte predominant Hodgkin lymphoma, express CD200. Here we show that CD200 is expressed by follicular helper T cells in reactive lymphoid tissue, using single-c...
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PMID: 21164290
PDF is available here.
PDF is available here.
Microbial Pathogenesis (49)6 2010
Abstract
These results provide definitive evidence that the morphine-mediated enhancement of oral Salmonella infection is dependent on the μ-opioid receptor.
Copyright © 2010 Elsevier Ltd. All rights reserved....
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PMID: 20688146
PDF is available here.
PDF is available here.
Hospital practice (1995) (38)4 2010
Abstract
A new era in medical science has dawned with the realization of the critical role of the "forgotten organ," the enteric flora, in health and disease. Central to this beneficial interaction between the flora and humans is the manner in which the bacteria contained within the gut "talk" to the immune...
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PMID: 21068536
PDF is available here.
PDF is available here.
Biochemical Journal (432)1 2010
Abstract
We generated mice deficient in either PKD1 or PKD2 enzymatic activity, via homozygous expression of PKD1(S744A/S748A) or PKD2(S707A/S711A) 'knockin' alleles. We also examined PKD2-deficient mice generated using 'gene-trap' technology. We demonstrate that, unlike PKD1, PKD2 catalytic activity is disp...
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PMID: 20819079
PDF is available here.
PDF is available here.
Journal of Immunology (185)7 2010
Abstract
We hypothesized that LMP1-mediated activation signals cooperate with and/or amplify events that predispose individuals to development of autoimmunity. To determine which aspects of autoimmunity may be exacerbated by LMP1, we bred mCD40-LMP1tg mice to two lupus-prone strains, B6.Sle1 and B6.Sle3, and...
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PMID: 20810985
PDF is available here.
PDF is available here.
Abstract
We have demonstrated notable stability of this cell population under physiologic and inflammatory conditions. Our results suggest that self-renewal of mature T(reg) cells serves as a major mechanism of maintenance of the T(reg) cell lineage in adult mice....
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PMID: 20929851
PDF is available here.
PDF is available here.
Abstract
Distribution and characterization of interlukin-10 (IL-10)-secreting cells in lymphoid tissues of pigs naturally infected with porcine circovirus type 2 (PCV2) were evaluated in accordance with PCV2 antigen detection. After screening a total of 56 pigs showing the symptoms of postweaning multisystem...
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PMID: 20706023
PDF is available here.
PDF is available here.
Abstract
We were able to identify and measure nine distinct rhesus IFN-alpha subtypes. Furthermore, we could demonstrate that in response to oral pathogenic SIV infection, several IFN-alpha subtypes are rapidly induced in lymphoid but not at oral and gastrointestinal mucosal surfaces. Although each IFN-alpha...
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PMID: 20616742
PDF is available here.
PDF is available here.
Genetika (Moskva) (46)9 2010
Abstract
The transcriptional domain of chicken alpha-globin genes was shown to contain the non-globin coding erythroid-specific TMEM8 gene inducible upon terminal differentiation of erythroblasts. Acquirement by the chicken TMEM8 gene of the erythroid-specific expression correlates with its approachment to t...
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PMID: 21061608
PDF is available here.
PDF is available here.
Abstract
We knocked out the expression of this protein class in T-cells or macrophages of mice by targeting the removal of the selenocysteine tRNA gene using loxP-Cre technology. Mice with selenoprotein-less T-cells manifested reduced pools of mature and functional T-cells in lymphoid tissues and an impairme...
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PMID: 20576203
PDF is available here.
PDF is available here.
Journal of General Virology (91)Pt 8 2010
Abstract
We compared the timing of abnormal prion protein (PrP(Sc)) dissemination and accumulation in the organism of susceptible sheep either orally inoculated or naturally infected with classical scrapie. Both animal groups shared a similar PrP(Sc) dissemination scheme and accumulation dynamics in lymphoid...
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PMID: 20444991
PDF is available here.
PDF is available here.
Abstract
We infected Epstein-Barr virus-transformed B cells with JCV and found that the viral genome decreased >1000-fold from days 0 to 20 after infection, which concurred with the absence of viral early and late messenger RNA transcripts and proteins. However, immunofluorescent images of B cells infected w...
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PMID: 20550458
PDF is available here.
PDF is available here.
Genes and Immunity (11)5 2010
Abstract
We show how variations in the expression of a chemokine receptor and in two components in the signaling pathway, Galpha(i2) and RGS1, affect the output fidelity of the signaling pathway. Examination of B cells from mice with varying numbers of intact alleles of Ccr7, Rgs1, Gnai2, and Gnai3 provided...
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PMID: 20508603
PDF is available here.
PDF is available here.
Autoimmunity Reviews (9)9 2010
Abstract
Abnormalities of memory B cells seem to be closely involved in the pathogenesis of primary Sjögrens Syndrome (pSS) and its malignant complication, B cell lymphoma. Recent studies on B cells in pSS add to our understanding of the distinct memory B cell subsets in pSS. Reduction of pe...
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PMID: 20452465
PDF is available here.
PDF is available here.
Abstract
Topical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some success to treat skin conditions including psoriasis and vitiligo. As well as targeting inflammatory processes in the skin, topical application of...
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PMID: 20211255
PDF is available here.
PDF is available here.
Abstract
We report on 3 patients with cutaneous mycotic infections (superficial dermatophytosis, 1 patient; trichophytia, 2 patients), who on histological examination revealed dense, superficial, and deep lymphoid infiltrates admixed with variable numbers of eosinophils and with large, atypical-looking, part...
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PMID: 20442640
PDF is available here.
PDF is available here.
Abstract
Our data indicate that compartmentalisation of the MS response is dependent on the lymphatic vascularisation of each coelomic cavity, limiting the effects or consequences of any stimulating or aggressive agents, as is the case with S. mansoni infection....
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PMID: 20721487
PDF is available here.
PDF is available here.
Journal of General Virology (91)Pt 7 2010
Abstract
I FCoV, over different time periods and with or without detectable viraemia. The colon was identified as the major site of FCoV persistence and probable source for recurrent shedding, but the virus was shown also to persist in several other organs, mainly in tissue macrophages. These might represent...
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PMID: 20237226
PDF is available here.
PDF is available here.
Abstract
We demonstrate that the IL-1 receptor IL-1R1 was selectively expressed by a subpopulation of iNK cells that localized proximal to IL-1beta-producing conventional dendritic cells (cDCs) within SLT. IL-1R1(hi) iNK cells required continuous exposure to IL-1beta to retain AHR and IL-22 expression, and t...
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PMID: 20620944
PDF is available here.
PDF is available here.
Journal of Immunology (184)12 2010
Abstract
We have analyzed the genes and expressed transcripts of the four TCR chains for the first time in a cartilaginous fish, the nurse shark (Ginglymostoma cirratum). Northern blotting found TCR mRNA expression predominantly in lymphoid and mucosal tissues. Southern blotting suggested translocon-type loc...
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PMID: 20488795
PDF is available here.
PDF is available here.
Avian Diseases (54)2 2010
Abstract
To determine the expression and distribution of tegument proteins encoded by duck enteritis virus (DEV) UL51 gene in tissues of experimentally infected ducks, for the first time, an immunoperoxidase staining method to detect UL51 protein (UL51p) in paraffin-embedded tissues is reported. A rabbit ant...
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PMID: 20608544
PDF is available here.
PDF is available here.
Journal of General Virology (91)Pt 6 2010
Abstract
These results demonstrate that CWD can be transmitted by aerosol (as well as nasal) exposure and suggest that exposure via the respiratory system merits consideration for prion disease transmission and biosafety....
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PMID: 20164261
PDF is available here.
PDF is available here.
Microbial Pathogenesis (48)5 2010
Abstract
We describe a new r-BCG expressing the gene Rv1767, induced by Mycobacterium tuberculosis during its survival in human macrophages. The r-BCG elicited a specific T cells response in Balb/c mice higher than wt BCG. The r-BCG amount used to immunise mice determined diverse Th1/Th2 equilibriums, which...
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PMID: 20219669
PDF is available here.
PDF is available here.
British Journal of Nutrition (103)10 2010
Abstract
We mainly focus on the uptake and accumulation of epicatechin metabolites in lymphoid organs, including the thymus, spleen and mesenteric lymphoid nodes, as well as in the liver and testes after a diet rich in cocoa. Ten young weaned Wistar rats were fed randomly with a 10 % (w/w) cocoa diet or a co...
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PMID: 20100378
PDF is available here.
PDF is available here.
Abstract
Genetic association analysis found a strong statistically significant correlation with the LTNP phenotype (single-nucleotide polymorphism rs1048412; P = .0004), independently of HLA-A10 influence. siRNA-based functional analysis showed that ZNRD1 down-regulation by siRNA or shRNA impaired HIV-1 repl...
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PMID: 20192730
PDF is available here.
PDF is available here.
Abstract
The cystic lesions in both the HIV+ and HIV- cases were microscopically analogous. However, a marked decrease in the interfollicular CD4:CD8 ratio was observed in all HIV+ CLH cases, which was statistically significant when compared with the HIV- cases (P = .02) and cases of LESA of Sjögren syndrom...
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PMID: 20303054
PDF is available here.
PDF is available here.
Abstract
The number of LA was in tight positive correlation with the severity of inflammation (r=0.9). The number of EGFR/HGFR positive subepithelial cells was found to be significantly elevated in severe (21.6+/-2.1%/21.3+/-1.9%), moderate (14.3+/-1.7%/14.6+/-1.6%) and mild (7.2+/-1.6%/7.4+/-1.3%) inflammat...
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PMID: 20132083
PDF is available here.
PDF is available here.
Abstract
SMC may participate in the formation of tertiary lymphoid tissue in atherosclerosis by upregulation of lymphorganogenic chemokines involved in T-lymphocyte, B-lymphocyte, and macrophage/dendritic cell attraction....
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PMID: 20139367
PDF is available here.
PDF is available here.
Abstract
We show that both topical ocular administration and topical intranasal administration of a mixture of immunodominant CD4(+) T-cell epitope peptides from herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) emulsified with the CpG(2007) mucosal adjuvant are capable of inducing local (in conjunctiv...
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PMID: 20089796
PDF is available here.
PDF is available here.
Abstract
Abstract
Conjunctival M cells bind and translocate sIgA from the tear film. Topical conjunctival immunization leads to generation of antigen-specific immunoglobulins from both local and distant mucosae and in serum. Natural antibodies, present in the tear film before immunization, may have contributed to sim...
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PMID: 19892871
PDF is available here.
PDF is available here.
The identification of intestinal M cells in the sacculus rotundus and appendix of the Angora rabbit.
Abstract
The present study was aimed at the immunohistochemical demonstration of M cells, found in the follicle-associated epithelium (FAE) of the sacculus rotundus (SR) and appendix of the Angora rabbit, using anti-vimentin primary antibodies, and at the determination of certain fine structural characterist...
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PMID: 20217227
PDF is available here.
PDF is available here.
Abstract
Transfusion (50)2 2010
Abstract
In BSE-infected macaques, blood lymphocyte-associated PrP(c) fluorescence gradually increased years before the onset of clinical signs (p(F test) < 0.0001). The increase in fluorescence intensity was detectable with MoAb 12F10, whereas we failed to detect an increase with 3F4. In parallel, plasma co...
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PMID: 19843289
PDF is available here.
PDF is available here.
Abstract
Audio, Transactions of the IRE Professional Group on (78 Suppl 1) 2010
Abstract
The aim of this study was to screen for cell surface markers that could discriminate CLL-type MBL from CLL or identify CLL cases likely to have stable disease.
Six color flow cytometry was performed on CLL-type MBL (n = 94) and CLL (n = 387) at diagnosis or relapse; 39 cases had poor-risk chromosoma...
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PMID: 20839337
PDF is available here.
PDF is available here.
Abstract
An improved indirect immunoperoxidase assay (IPA) was developed to detect antigens of Duck swollen head hemorrhagic disease virus (DSHDV) in paraformaldehyde-fixed, paraffin-embedded tissues of Pekin ducks (Anas platyrhynchos). This technique used an indirect streptavidin-alkaline phosphatase labeli...
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PMID: 20093677
PDF is available here.
PDF is available here.
Abstract
We will initially focus on historical literature describing lymph node (LN) anlage development and then on the contemporary understanding of the molecular mechanisms driving LN and Peyer's patch (PP) formation. Utilizing transgenic reporters and gene knockout mice, the interplay between hematopoieti...
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PMID: 20800822
PDF is available here.
PDF is available here.
Abstract
We argue that lymphoid tissue inducer cells played a pivotal role not only in the development of organized lymphoid structures but also in the subsequent genesis of the CD4-dependent class-switched memory antibody responses that depend on an organized infrastructure to work. In this review, we conce...
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PMID: 20800820
PDF is available here.
PDF is available here.
Abstract
We argue that lymphoid tissue inducer cells played a pivotal role not only in the development of organized lymphoid structures but also in the subsequent genesis of the CD4-dependent class-switched memory antibody responses that depend on an organized infrastructure to work. In this review, we conce...
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PMID: 20800820
PDF is available here.
PDF is available here.
Current Eye Research (35)1 2010
Abstract
These results indicate that particulate antigen can be taken up by the conjunctiva and transported to the draining lymph nodes, showing that antigen does not need to access nasal-associated lymphoid tissue to induce tear IgA antibody responses....
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PMID: 20021248
PDF is available here.
PDF is available here.
Abstract
The objective of the present study was to analyse changes of morphological properties in the organs of immune and endocrine systems in subjects with opioid addiction and chronic alcoholic intoxication (CAI) based on the results of 322 autopsies. These included 190 cases of drug addiction from 0.5 to...
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PMID: 20394195
PDF is available here.
PDF is available here.
Abstract
We document a rare case of primary non-Hodgkin's lymphoma of the parotid gland arising in the background of LESA and with a rare example of transformation from low grade to high-grade B cell lymphoma of MALT type....
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PMID: 20551561
PDF is available here.
PDF is available here.
Abstract
We have addressed this obstacle by investigating VZV infection of human tissue xenografts in the severe combined immunodeficiency mouse model. In studies relevant to the pathogenesis of primary VZV infection, we have examined VZV infection of human T cell (thymus/liver) and skin xenografts. This wor...
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PMID: 20397071
PDF is available here.
PDF is available here.
Folia Biologica (Krakow) (58)1-2 2010
Abstract
Blood cell counts, differential blood cell counts and weights of the spleen and peripheral lymph nodes draining the area of lesions induced by Moloney sarcoma virus inoculation into the quadriceps shank muscles of inbred BALB/c mice were examined at various stages of tumor development and regression...
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PMID: 20420189
PDF is available here.
PDF is available here.
Abstract
We studied the effect of interleukin-1beta on functional activity of lymphoid structures in the gastrointestinal tract of rats with various behavioral parameters during stress of simultaneous immobilization and electrocutaneous stimulation. Morphofunctional characteristics of lymphoid tissue were es...
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PMID: 20396745
PDF is available here.
PDF is available here.
Mucosal Immunology (2)6 2009
Abstract
We created transgenic mice-expressing CXCL13 in intestinal epithelial cells. CXCL13 expression promoted a marked increase in the number of B cells in the lamina propria and an increase in the size and number of lymphoid follicles in the small intestine. Surprisingly, these changes were associated wi...
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PMID: 19741597
PDF is available here.
PDF is available here.
Mucosal Immunology (2)6 2009
Abstract
We observed APRIL expression, together with TACI (transmembrane activator and CAML interactor) and BCMA (B-cell maturation antigen), in gut-associated lymphoid tissue (GALT), lamina propria, and in the epithelium of stomach, small and large intestine, and rectum. However, no activation-induced cytid...
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PMID: 19741596
PDF is available here.
PDF is available here.
Mucosal Immunology (2)6 2009
Abstract
Intestinal lymphoid tissues face the challenging task of inducing adaptive immunity to pathogens, yet maintaining homeostasis with the enormous commensal microbiota. To that aim, the ancient partnership between self and flora has resulted in the generation of a unique set of lymphoid...
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PMID: 19741595
PDF is available here.
PDF is available here.
Abstract
We review the current understanding of the role of beta(7) integrins in intestinal lymphocyte trafficking and retention in health and disease....
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PMID: 19860663
PDF is available here.
PDF is available here.
Alternatives to Laboratory Animals (37 Suppl 1) 2009
Abstract
We believe the best viable option available is to use human cells and/or tissues in a functional in vitro model of human physiology. Not only will this more accurately model human diseases, it will also eliminate any ethical, moral and scientific issues involved with use of live humans and animals....
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PMID: 19807200
PDF is available here.
PDF is available here.
Abstract
We discuss six of the common entities that can present as atypical lymphoid hyperplasia and thus can mimic malignant lymphomas, with emphasis on morphologic features, immunophenotypic findings, and molecular correlates that help distinguish these disorders from neoplastic conditions. The six conditi...
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PMID: 19577167
PDF is available here.
PDF is available here.
Avian Pathology (38)4 2009
Abstract
Mortality in excess of 65% occurred in a flock of 450 canaries (Serinus canaria). Clinical signs in the canaries included severe respiratory distress, loss of feathers and/or scaly skin on the head, neck and back, anorexia, loss of weight and fluffed-up appearance of several days duration before dea...
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PMID: 19937516
PDF is available here.
PDF is available here.
Abstract
We monitored clinical, biochemical, histological and serological parameters among FIVple-positive (N=47) as compared to FIVple-negative (N=17) lions anesthetized and sampled on multiple occasions between 1999 and 2006 in Botswana. Relative to uninfected lions, FIVple-infected lions displayed a signi...
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PMID: 19464039
PDF is available here.
PDF is available here.
Abstract
A 61-year-old woman was referred to our hospital because of an abnormal chest X-ray shadow. She was diagnosed as having primary Sjögren's syndrome based on sicca syndrome, polyclonal hyper-gamma-globulinemia, and positive results for anti-Ro/SS-A and anti-La/SS-B antibodies. Her chest CT scan rev...
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PMID: 19637801
PDF is available here.
PDF is available here.
Abstract
We examined injury-elicited changes in murine ERV (MuERV) expression in lymphoid tissues and characterized biological properties of the putative MuERVs isolates. Female C57BL/6J mice were subjected to approximately 18% total-body-surface-area burn injury. Four different lymphoid tissues (blood, bone...
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PMID: 18948849
PDF is available here.
PDF is available here.