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Virus Diseases (19)
Articles on Virus Diseases
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Immunity and immunopathology to viruses: what decides the outcome?
Nat Rev Immunol 10(7):514-26 (2010) PMID 20577268
We focus on host factors that influence the outcome of viral infection, including genetic susceptibility, the age of the host when infected, the dose and route of infection, the induction of anti-inflammatory cells and proteins, as well as the presence of concurrent infections and past exposure to c... -
Equine disease surveillance, January to March 2010.
Vet Rec 166(26):808-11 (2010) PMID 20581357
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A randomized controlled trial of low-dose recombinant human interferons @a-2b nasal spray to prevent acute viral respiratory infections in m...
Vaccine 28(28):7 (2010) PMID 20394720
We performed this randomized controlled trial. The results showed that application of the rIFNalpha-2b nasal spray had the benefits in prevention of infections caused by influenza A virus, influenza B virus parainfluenza viruses 1-3 and adenovirus species B. However, no benefit was seen in preventin... -
An update on management of severe acute infectious gastroenteritis in children.
Expert Rev Anti Infect Ther 8(6):671-82 (2010) PMID 20521895
We will consider severe acute infectious gastroenteritis as follows: watery diarrhea accompanied by, or at high risk for, moderate to severe dehydration due to abrupt onset of vomiting that reduces oral intake, and/or frequent emission of liquid stools, or moderate to severe dysenteric/bloody diarrh... -
Effect of surfactants, temperature, and sonication on the virucidal activity of polyhexamethylene biguanide against the bacteriophage MS2
Am J Infect Control 38(5):6 (2010) PMID 20006410
Temperature had a key role in increasing significantly the virucidal activity of VANTOCIL TG, reducing virus concentration by 4-log(10) within 10 minutes at 40 degrees C. The high temperature was linked to a reduction of viral aggregates despite the exposure to the biguanide. In addition, the viral... -
Potential solutions to problems posed by the offspring sex ratios of people with parasitic and viral infections.
Folia Parasitol (Praha) 57(2):114-20 (2010) PMID 20608473
I have hypothesized that mammalian offspring sex ratios (proportions male at birth) are partially controlled by the hormone levels of both parents around the time of conception. Recently data have been published (privately) which impugn suggestions of mine (based on that hypothesis) relating to the... -
Cross-priming in health and disease.
Nat Rev Immunol 10(6):403-14 (2010) PMID 20498667
We have only recently gained insight into the underlying cellular and molecular mechanisms, and we are just beginning to understand its physiological importance in health and disease. Here we summarize current concepts on the cross-talk between the immune cells involved in CTL cross-priming and on i... -
Molecular diagnosis of respiratory viruses.
Future Microbiol 5(6):901-16 (2010) PMID 20521935
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Recognising and managing Guillain-Barré syndrome.
Emerg Nurse 18(3):27-30 (2010) PMID 20608399
Guillain-Barré syndrome, a randomly acquired inflammatory condition that can lead to progressive muscle weakness and paralysis, is a rare presentation in emergency departments, and differentiating its early stages from common viral illnesses can be difficult. Emergency practitioners should be aware... -
The novel applications of the quantitative analysis of neutrophil cell surface FcgammaRI (CD64) to the diagnosis of infectious and inflammat...
Curr Opin Infect Dis 23(3):268-74 (2010) PMID 20407370
It is shown here that although the high number of FcgammaRI on neutrophils is a sensitive marker of bacterial infection, it is highly expressed also in DNA virus infections. As a consequence, neutrophil FcgammaRI cannot be used in distinguishing between bacterial and viral infections. It is also cle...