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DNA Virus Infections (9):
Recent article
DNA Virus Infections
Abstract
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Abstract
We identify a central role for AIM2 in regulating caspase-1-dependent maturation of IL-1beta and IL-18, as well as pyroptosis, in response to synthetic double-stranded DNA. AIM2 was essential for inflammasome activation in response to Francisella tularensis, vaccinia virus and mouse cytomegalovirus...
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PMID: 20351692
PDF is available here.
PDF is available here.
Abstract
To investigate the prevalence of transfusion-transmitted virus (TTV) and human papillomavirus (HPV) co-infection in cervical smears of patients with cervical lesions in littoral of Zhejiang province and analysis of transmitted route.
Nested polymerase chain reaction (nPCR) was established. TTV DNA w...
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PMID: 21110428
PDF is available here.
PDF is available here.
Journal of Fish Diseases (33)2 2010
Abstract
Viruses in three genera of the family Iridoviridae (iridoviruses) affect finfish. Ranaviruses and megalocytiviruses are recently emerged pathogens. Both cause severe systemic disease, occur globally and affect a diversity of hosts. In contrast, lymphocystiviruses cause superficial le...
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PMID: 20050967
PDF is available here.
PDF is available here.
Abstract
Our results also show that WSSV found in Bahia and Santa Catarina very likely originated from different sources of contamination....
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PMID: 20225670
PDF is available here.
PDF is available here.
Bratislavske lekarske listy (111)12 2010
Impact of TTV and SENV infection in chronic hepatitis B or C on liver histology and therapy outcome.
Abstract
We have found 9 and 3 SENV positive (p < 0.05) and 18 and 28 TTV positive patients, respectively (not significant). However 11 of 32 biopsy samples obtained in the responder's group and 19 of 31 in non-responders were TTV positive (p < 0.05). No similar differences were observed among 23 chronic hep...
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PMID: 21384729
PDF is available here.
PDF is available here.
Abstract
Chronic intestinal pseudo-obstruction (CIPO), one of the most severe gastrointestinal motility disorders, is a condition characterized by a clinical picture mimicking small bowel occlusion with related symptoms and signs in the absence of demonstrable mechanical obstruction. Analysis of full-thickne...
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PMID: 20172270
PDF is available here.
PDF is available here.
Journal of General Virology (91)Pt 1 2010
Abstract
We named them chimpanzee stool-associated circular viruses (ChiSCV). Further metagenomic studies of animal samples will greatly increase our knowledge of viral diversity and evolution....
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PMID: 19759238
PDF is available here.
PDF is available here.
Abstract
We know, this is the first report of a ranaviral infection affecting aquatic organisms in Brazil. Additionally, our results suggest that American bullfrogs may have served as a vector of transmission of this virus, which highlights the potential threat of amphibian translocation in the world distrib...
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PMID: 20066953
PDF is available here.
PDF is available here.
Abstract
Ranaviruses are known to cause mortality in a variety of anuran species and have the potential to significantly impact wild and captive frog populations. In this study, 16 captive frogs and toads from the Louisville Zoological Garden were examined for the presence of ranavirus; this group included 1...
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PMID: 19746873
PDF is available here.
PDF is available here.
Abstract
We used the expression of proinflammatory cytokines (IFN-gamma and IL-12p40) and production of nitric oxide (NO) as indicators to evaluate the involvement of the signaling cascades in the activation of HD11 cells by BV. Western blot analysis revealed that ERK1/2, p38 MAPK and JNK were phosphorylated...
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PMID: 19303463
PDF is available here.
PDF is available here.
Abstract
We used the expression of proinflammatory cytokines (IFN-gamma and IL-12p40) and production of nitric oxide (NO) as indicators to evaluate the involvement of the signaling cascades in the activation of HD11 cells by BV. Western blot analysis revealed that ERK1/2, p38 MAPK and JNK were phosphorylated...
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PMID: 19303463
PDF is available here.
PDF is available here.
Abstract
We estimated mortality and examined size distribution, condition, and biomass following the outbreak. Boat-mounted electrofishing was used to collect largemouth bass for a mark-recapture population estimate and other population metrics. Fish samples were examined for evidence of LMBV, other infectio...
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PMID: 19617487
PDF is available here.
PDF is available here.
Abstract
Currently, the origin of autoimmune diseases is considered to be multifactorial. Genetic predisposition, immune system malfunction or even backfire, hormonal regulation, and environmental factors, i.e. infections, all play important roles in the pathogenesis of autoimmune diseases such as the antiph...
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PMID: 19089659
PDF is available here.
PDF is available here.
Theriogenology (71)9 2009
Abstract
Routes of swine torque teno virus (TTV) transmission have been minimally investigated in the pig population. Current knowledge suggests the faecal-oral route as the most probable way of viral dissemination. Other transmission routes, such as mother-to-infant, have been studied in humans, but no info...
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PMID: 19249089
PDF is available here.
PDF is available here.
Abstract
We collected tissue samples from 2003 to 2006 in 4 geographically separated tiger salamander Ambystoma tigrinum nebulosum host populations on the Kaibab Plateau in northern Arizona. We tested for Ambystoma tigrinum virus (ATV), a lethal ranavirus of tiger salamanders, calculated ATV prevalence for e...
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PMID: 19593927
PDF is available here.
PDF is available here.
Abstract
A survey for the amphibian pathogens ranavirus and Batrachochytrium dendrobatidis (Bd) was conducted in Denmark during August and September 2008. The public was encouraged via the media to register unusual mortalities in a web-based survey. All members of the public that registered cases were interv...
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PMID: 19593928
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe the pathology, isolation and characterisation of a virus responsible for an outbreak of a systemic haemorrhagic disease causing high mortality in tadpoles of the common midwife toad Alytes obstetricans in the 'Picos de Europa' National Park in northern Spain. The virus, provisionally des...
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PMID: 19476279
PDF is available here.
PDF is available here.
Abstract
These results were used to guide a statewide fish stocking strategy aimed at preventing the spread of LMBV in Texas and to contribute to a nationwide effort to understand this virus and its effects on largemouth bass fisheries....
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PMID: 19485124
PDF is available here.
PDF is available here.
Abstract
We examined the effects of the herbicide atrazine and the insecticide chlorpyrifos on the susceptibility of tiger salamander larvae, Ambystoma tigrinum, to a viral pathogen, Ambystoma tigrinum virus (ATV). Environmentally relevant concentrations of atrazine (0, 20, 200 microg/L) and chlorpyrifos (0,...
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PMID: 19415385
PDF is available here.
PDF is available here.
Abstract
We examined the effects of the herbicide atrazine and the insecticide chlorpyrifos on the susceptibility of tiger salamander larvae, Ambystoma tigrinum, to a viral pathogen, Ambystoma tigrinum virus (ATV). Environmentally relevant concentrations of atrazine (0, 20, 200 microg/L) and chlorpyrifos (0,...
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PMID: 19415385
PDF is available here.
PDF is available here.
Abstract
We examined the effects of the herbicide atrazine and the insecticide chlorpyrifos on the susceptibility of tiger salamander larvae, Ambystoma tigrinum, to a viral pathogen, Ambystoma tigrinum virus (ATV). Environmentally relevant concentrations of atrazine (0, 20, 200 microg/L) and chlorpyrifos (0,...
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PMID: 19415385
PDF is available here.
PDF is available here.
Abstract
We isolated the full-length cDNAs of the mandarin fish (Siniperca chuatsi) alpha inhibitor of NF-kappaB (ScIkappaBalpha) and p65 NF-kappaB (Scp65). Multiple sequence alignments showed that the amino acid sequences of both ScIkappaBalpha and Scp65 contain conserved domains similar to those of mammali...
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PMID: 19340946
PDF is available here.
PDF is available here.
Abstract
In order to study the pathogenicity of ranaviruses to a wild European freshwater fish species, pike Esox lucius fry were challenged with the following Ranavirus isolates: epizootic haematopoietic necrosis virus (EHNV), European sheatfish virus (ESV), European catfish virus (ECV), pike-perch iridovir...
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PMID: 19402450
PDF is available here.
PDF is available here.
Journal of Fish Diseases (32)2 2009
Abstract
Immunohistochemistry (IHC) and in situ hybridization (ISH) techniques have been used for the detection of lymphocystis disease virus (LCDV) in formalin-fixed, paraffin-embedded tissues from gilt-head seabream, Sparus aurata L. Diseased and recovered fish from the same population were analysed. IHC w...
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PMID: 18803582
PDF is available here.
PDF is available here.
Archives of Virology (154)8 2009
Abstract
Sera from 15 patients coinfected with TTV and HIV-1, collected before and at two times after introduction of highly active anti-retroviral therapy (HAART), were tested for TTV load and the presence of the five highly divergent TTV phylogenetic groups. Seven patients showed a 1-5 log TTV load decreas...
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PMID: 19585076
PDF is available here.
PDF is available here.
Abstract
In our study, multiplex PCR based detection system was found useful in detecting opportunistic viruses in HIV infected individuals. Though EBV is the most prevalent opportunistic viral infection among HIV infected individuals, there was no significant association between EBV load, CD4+ T cell counts...
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PMID: 19584500
PDF is available here.
PDF is available here.
Abstract
VP37 has been successfully expressed in E. coli. VP37 interacted with shrimp cells. SIGNIFICANCE AND IMPACT OF THE STUDY: The results suggest that rVP37 has a potential application in prevention of virus infection....
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PMID: 19018966
PDF is available here.
PDF is available here.
Abstract
Since 1997, groups of novel nonenveloped DNA viruses with a circular, single-stranded (negative sense) DNA genome of 3.6-3.9 kb, 3.2 kb, or 2.8-2.9 kb in size have been discovered and designated Torque teno virus (TTV), Torque teno midi virus (TTMDV), and Torque teno mini virus (TTMV), respectively,...
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PMID: 19230554
PDF is available here.
PDF is available here.
Abstract
Many features of the Torque teno virus and the other anelloviruses (AVs) that have been identified after this virus was discovered in 1997 remain elusive. The immunobiology of the AVs is no exception. However, evidence is progressively accumulating that at least some AVs have an interesting interpla...
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PMID: 19230558
PDF is available here.
PDF is available here.
Abstract
A role for the ubiquitous Torque teno (TT) viruses in the pathogenesis of disease has not been resolved. In vivo and in vitro intragenomic rearrangement of TT virus genomes has been demonstrated. Replication in cell culture of a subviral molecule (411 bp) occurs through oligomerisation of RNA transc...
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PMID: 19230559
PDF is available here.
PDF is available here.
Abstract
Torque teno (TT) viruses have been more frequently reported in malignant biopsies when compared to normal control tissue. The possible contribution of TT virus infection to human carcinogenesis or the potential oncolytic functions of these virus infections are being discussed based on available expe...
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PMID: 19230560
PDF is available here.
PDF is available here.
Abstract
Abstract
Infection with TT virus (Torque teno virus, TTV), a small, nonenveloped virus with a circular, single-stranded DNA genome classified in the floating genus Anellovirus, is not restricted to humans. Using highly conserved primers derived from the untranslated region of the human TTV genome, a variety...
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PMID: 19230556
PDF is available here.
PDF is available here.
Abstract
The host cells and the events in the cells during Torque teno (TT) virus infection are at present unknown. Replicating TT virus DNA has been detected in liver, in peripheral blood mononuclear cells (PBMC), and in bone marrow. By alternative splicing this small virus generates three mRNA species, fro...
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PMID: 19230557
PDF is available here.
PDF is available here.
Abstract
To determine whether genogroup 1 porcine torque teno virus (g1-TTV) can potentiate clinical disease associated with porcine circovirus type 2 (PCV2).
33 gnotobiotic baby pigs.
Pigs were allocated into 7 groups: group A, 5 uninoculated control pigs from...
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PMID: 19046008
PDF is available here.
PDF is available here.
Abstract
To determine whether genogroup 1 porcine torque teno virus (g1-TTV) can potentiate clinical disease associated with porcine circovirus type 2 (PCV2).
33 gnotobiotic baby pigs.
Pigs were allocated into 7 groups: group A, 5 uninoculated control pigs from...
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PMID: 19046008
PDF is available here.
PDF is available here.
Acta Paediatrica (97)12 2008
TT virus prevalence, viral loads and genotypic variability in saliva from healthy Japanese children.
Abstract
TTV DNA was detected in 6, 34 and 90% of children aged 1, 4 and 42 months, respectively, and in 84% of adults. Comparable levels of TTV DNA were detected in pairs of saliva and PBMC. TTV loads in saliva were much higher in children than in adults. G3 was the most common genogroup in all age groups....
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PMID: 18671690
PDF is available here.
PDF is available here.
Conservation Biology (22)6 2008
Abstract
We screened tiger salamanders involved in the bait trade in the western United States for both ranaviruses and Bd with polymerase chain reaction and used oral reports from bait shops and ranavirus DNA sequences from infected bait salamanders to determine how these animals and their pathogens are mov...
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PMID: 18717688
PDF is available here.
PDF is available here.
Abstract
TTV infections are more frequent in infants and young children exposed to often contacts with medical environment, children from poor social conditions and with chronic diseases in near family....
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PMID: 19205375
PDF is available here.
PDF is available here.
Abstract
Torque teno virus (TTV) belongs to the floating genus of Anellovirus. It was discovered in a human patient, and later it was also found in animals including pigs. The aim of this study was to investigate the presence and estimate the prevalence of swine TTV in Hungarian pig herds for the first time,...
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PMID: 19149109
PDF is available here.
PDF is available here.
Journal of Hepatology (49)6 2008
Abstract
There is no reason to withhold HCV therapy in HIV infected patients who have access to HAART, because of occult HBV, GBV-C or SEN-V co-infections....
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PMID: 18752863
PDF is available here.
PDF is available here.
Abstract
SENV DNA was detected in 8 of 67 (12%) HIV/HCV coinfected patients, in 9 of 77 (11.7%) HIV monoinfected patients, in 21 of 95 (22%) HCV monoinfected patients, and 12 of 122 (9.8%) healthy blood donors. HIV monoinfected patients showed the highest mean SENV H DNA level. The mean SENV H DNA was signif...
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PMID: 19073384
PDF is available here.
PDF is available here.
Abstract
A diverse class of proteins called lectins plays a major role in shrimp innate immunity. In this study, the cDNA encoding a C-type lectin of Penaeus monodon (PmLT) was cloned, and its potential role examined. Despite the low overall amino acid sequence identity with other animal lectins, PmLT includ...
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PMID: 18793643
PDF is available here.
PDF is available here.
Abstract
TTV-DNA was detected in 137 of 513 (26.7%) patients with liver diseases and 38 of 65 (58.5%) patients with chronic renal failure. TTV was also detected in 27% of healthy controls. The sequence analysis of the PCR product from 10 randomly selected cases failed to show a significant sequence divergenc...
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PMID: 18932284
PDF is available here.
PDF is available here.
Abstract
We investigate what role MAVS may play in apoptosis. Induction of cell death led to the rapid cleavage of MAVS, resulting in its release from the outer mitochondrial membrane. This cleavage is blocked in cells incubated with proteasome or caspase inhibitors. Transfection of synthetic viral dsRNA and...
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PMID: 18692023
PDF is available here.
PDF is available here.
Transplant International (21)10 2008
Abstract
Few studies have been performed on the prevalence of Torque Teno Virus (TTV) infection in liver transplant (LT) recipients. The aim of this study was to assess the prevalence, viremia and genogroup pattern of TTV among LT patients and to ascertain whether TTV causes liver damage in liver transplante...
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PMID: 18564988
PDF is available here.
PDF is available here.
Environmental Microbiology (10)10 2008
Abstract
The concept of polymicrobial disease is well accepted in human and veterinary medicine but has received very little attention in the field of aquaculture. This study was conducted to investigate the synergistic effect of white spot syndrome virus (WSSV) and Vibrio campbellii on development of diseas...
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PMID: 18616551
PDF is available here.
PDF is available here.
Abstract
These results suggest that certain amphibians and chelonians are infected with a similar virus and that different viruses exist among different chelonians. Amphibians may serve as a reservoir host for susceptible chelonians. This report also demonstrated that significant disease associated with Rana...
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PMID: 18957641
PDF is available here.
PDF is available here.
Virus Research (137)1 2008
Abstract
We have emphasized the many similarities between human anellovirus and avian circoviruses and the cell and tissue types infected by these pathogens. We have done this in order to explore whether knowledge acquired from natural and experimental avian infections could reflect and be extrapolated to th...
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PMID: 18656506
PDF is available here.
PDF is available here.
Abstract
We reported two C1q-like cDNAs from mandarin fish (Siniperca chuatsi), mC1q-like-1 (mC1qL1) and mC1q-like-2 (mC1qL2). The full-length cDNA of mC1qL1was 990bp, containing a 71bp 5'-untranslated region (UTR), an open reading frame (ORF) of 723bp, and a 196bp long 3'-UTR. mC1qL2 cDNA was 1193bp, contai...
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PMID: 18571244
PDF is available here.
PDF is available here.
Abstract
A cytopathological methodology was used to analyze infection by Bombyx mori multiple nucleopolyhedrovirus (BmMNPV), a geographic isolate of the family Baculoviridae, in the caterpillar testes of the B. mori. Japanese B. mori strain caterpillar, fifth instar, were inoculated with BmMNPV and their tes...
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PMID: 18590914
PDF is available here.
PDF is available here.
Journal of General Virology (89)Pt 9 2008
Abstract
A combined functional investigation on the four per os infectivity factors (PIFs) of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (HearNPV) was conducted in this study. HearNPV bacmids with deletions of p74 (Ha20), pif1 (Ha111), pif2 (Ha132) and pif3 (Ha98) were constructed individu...
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PMID: 18753243
PDF is available here.
PDF is available here.
Journal of Immunotherapy (31)7 2008
Abstract
We now describe a modified rapid selection method for production and characterization of CD4 and CD8 T cells specific for cytomegalovirus, Epstein-Barr virus, and adenovirus in a single infusate. We use Ad5f35-pp65/latent membrane protein 2 vectors in a single procedure over a 48-hour time period an...
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PMID: 18600178
PDF is available here.
PDF is available here.
Abstract
DNA virus score (DNAVS) point, which incorporates quantitative analysis of CD64 on neutrophils and total and differential count of leukocytes, varied between 0 and 8, and displayed 95% sensitivity and 100% specificity in distinguishing between dsDNA and ssRNA virus infections [average (S.D.); DNAVS...
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PMID: 18499515
PDF is available here.
PDF is available here.
Abstract
Foremost among the newly described antiviral agents that may be developed into drugs are, for the treatment of human papilloma virus (HPV) infections, cPrPMEDAP; for the treatment of herpes simplex virus (HSV) infections, BAY 57-1293; for the treatment of varicella-zoster virus (VZV) infections, FV-...
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PMID: 18764719
PDF is available here.
PDF is available here.
Abstract
Four species (Dendrobates auratus, Phyllobates terribilis, Pyxicephalus adspersus, and Rhacophorus dennysi) of captive anurans with a clinical history of lethargy and inappetence were found dead and were submitted for necropsy. Gross lesions included irregular patches of sloughed skin and rare derma...
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PMID: 18817009
PDF is available here.
PDF is available here.
Veterinary Journal (177)3 2008
Abstract
During an on-going amphibian ecology study, a free-ranging American bullfrog (Rana catesbeiana) metamorph was captured in a pitfall trap adjacent to a constructed farm pond at the Plateau Research and Education Center (PREC) on the Cumberland Plateau near Crossville, Tennessee, USA. Grossly, the rig...
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PMID: 17604194
PDF is available here.
PDF is available here.
Abstract
Respiratory viruses are important human pathogens, affecting both healthy individuals and immunocompromised patients. In the past decade several new human respiratory viruses have been described, some of which have the potential to start an epidemic. At the same time, influenza A viruses continue to...
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PMID: 18666032
PDF is available here.
PDF is available here.