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Eye Infections, Viral (4):
Recent article
Eye Infections, Viral
Abstract
In recent years, infectious agents have been increasingly recognised as an important pathogenetic factor for various malignant tumours of the ocular adnexa. Many of these viruses and bacteria affect the cell cycle and physiological apoptosis. Ocular adnexal lymphoma (OAL), especially extranodal marg...
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PMID: 20535664
PDF is available here.
PDF is available here.
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Abstract
We started administration of ganciclovir. There was resolution of the inflammation; however, bullous keratopathy was subsequently noted in the cornea. Additional PKP was performed with perioperative intravenous administration of ganciclovir. The failed graft obtained during the additional PKP was su...
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PMID: 20458221
PDF is available here.
PDF is available here.
Abstract
Topical CsA 1% is a safe and effective alternative treatment in patients with SEIs who do not respond to other treatment modalities or have unwanted side effects from topical steroids....
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PMID: 20458220
PDF is available here.
PDF is available here.
Abstract
Abstract
Thirty-two patients were diagnosed with acute retinal necrosis from 1998 to 2007. Twenty patients (25 eyes) had at least 1 follow-up and available medical records. Intravitreal injections of ganciclovir and/or foscarnet were administered in 11 of 25 eyes. Intravenous and oral antiviral medications w...
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PMID: 20057342
PDF is available here.
PDF is available here.
Abstract
In this largest reported series of FHC patients, we detected a strong association between FHC and intraocular antibody synthesis against rubella virus. Furthermore, in 11 patients, it was possible to confirm an additional intraocular antibody synthesis, in particular HSV. PCR-positive results in the...
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PMID: 19937050
PDF is available here.
PDF is available here.
Abstract
Optical coherence tomography patterns as predictors of visual outcome in dengue-related maculopathy.
Abstract
Mean age was 28.7 years and there were more men (53.7%). The most common visual complaints were blurring of vision (51.2%) and central scotoma (34.1%). Most patients recovered best-corrected visual acuity >20/40. Optical coherence tomography showed 3 patterns of maculopathy: 1) diffuse retinal thick...
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PMID: 20094013
PDF is available here.
PDF is available here.
Abstract
Abstract
Journal of Virology (84)1 2010
Abstract
We establish 17-beta estradiol (17-betaE) treatment of latently infected ovariectomized mice induces viral reactivation, as demonstrated by increased viral load and increased immediate-early viral gene expression in the latently infected trigeminal ganglia (TG). Interestingly, the increased HSV reac...
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PMID: 19846508
PDF is available here.
PDF is available here.
Abstract
Stress from surgery and corticosteroid usage can revitalize CMV activity. PCR and confocal microscopy are valuable for the diagnosis of CMV corneal endotheliitis....
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PMID: 20037910
PDF is available here.
PDF is available here.
Abstract
To determine the vitreous penetration of penciclovir (Denavir; GlaxoSmithKline, Philadelphia, Pennsylvania, USA) after oral administration of the prodrug famciclovir (Famvir; Novartis Pharmaceuticals Corp, East Hanover, New Jersey, USA).
Prospective interventional cas...
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PMID: 19375688
PDF is available here.
PDF is available here.
Abstract
Iris atrophy and pupillary dilation in a patient with unexplained anterior uveitis suggests the diagnosis of HSV keratouveitis....
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PMID: 19491988
PDF is available here.
PDF is available here.
Abstract
We found specific cytokine profiles for each type of uveitis, with large interindividual variations and no etiological or clinical correlations. Ocular cytokine mapping contributes to a better understanding of the physiopathology of specific forms of uveitis and provides guidance for new targeted tr...
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PMID: 19302012
PDF is available here.
PDF is available here.
Abstract
Fifty-nine per cent of the surgeons and assistants refused to wear facemasks with a visor. The incidence of blood splashes in those who participated was 45%. There was a trend for blood splashes to be more common during major surgery and during elective surgery. Surgeons and assistants were subject...
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PMID: 19405330
PDF is available here.
PDF is available here.
Abstract
We studied the presence of HPV genome in RB tumor samples from patients with unilateral tumor. Forty-four fresh RB tumor samples and 30 non-neoplastic donor retinas were analyzed for the presence of HPV 16 and 18 genome by nested and seminested polymerase chain reaction. Tumor tissue sections were a...
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PMID: 19125079
PDF is available here.
PDF is available here.
Abstract
We review sexually transmitted diseases (STD) involving the eye. Recently conjunctivitis due to Chlamydia trachomatis in children and adults is increasing, and that of Neisseria gonorrhoeae resistant to multiple antibiotics has attracted special attention in our country. Syphilis has many ocular man...
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PMID: 19177759
PDF is available here.
PDF is available here.
Abstract
There is neither an association between the severity of chickenpox and the severity of ocular involvement nor an association between the presence of a varicella eyelid rash and the development of uveitis. As the prognosis regarding sequelae of ocular involvement in varicella infection is good, only...
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PMID: 19882590
PDF is available here.
PDF is available here.
Abstract
Up to now, HPV has been blamed as the major viral pathogen in the etiopathogenesis of pterygium. The current results suggest that EBV may also be involved in the pathogenesis of pterygium, but further larger studies with larger cohorts are required to confirm this hypothesis....
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PMID: 19253231
PDF is available here.
PDF is available here.
Abstract
All SPF cats developed clinical and clinicopathologic evidence of upper respiratory tract and ocular disease only. Via PCR assay, FHV-1 DNA was detected in blood of all SPF cats at least once between 2 and 15 days after inoculation. Feline herpesvirus type 1 DNA was detected in conjunctival swabs of...
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PMID: 19119954
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
We report a case of a 48-year-old female patient, who presented with defective vision two weeks after a serology proven chikungunya infection. There was bilateral neuroretinitis with peripapillary cotton wool spots. These findings should be kept in mind as an ocular manifestation of chikungunya viru...
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PMID: 19237792
PDF is available here.
PDF is available here.
Abstract
There are no clinically detectable differences between CMV-positive and negative presumed PSS eyes. CMV-positive presumed FHI patients are more likely to be male, older at diagnosis or have nodular endothelial lesions....
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PMID: 19027423
PDF is available here.
PDF is available here.
Avian Diseases (52)4 2008
Abstract
These results enhance our understanding of the nature and pattern of MDV infection in the eye....
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PMID: 19166047
PDF is available here.
PDF is available here.
Abstract
We report a case of a 45-year old Filipino post-kidney transplant patient maintained on steroids, who presented with floaters in her left eye. Vitreous aspirate was analyzed using polymerase chain reaction (PCR) for human cytomegalovirus (HCMV) and herpes simplex virus (HSV). A distinct band (435 bp...
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PMID: 19062695
PDF is available here.
PDF is available here.
Abstract
HAART may be the cause for decline in the prevalence of ocular diseases and visual impairment in HIV/AIDS patients. CD4 count and WHO clinical stage may help predict their occurrence....
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PMID: 18952644
PDF is available here.
PDF is available here.
Abstract
In five out of seven patients unilateral ARN occurred after HE under immunocompetent conditions, and both ARN and HE were caused by the herpes simplex virus (HSV), whereas the other two patients were immunocompromised, had bilateral ARN, and both ARN and HE were caused by the varicella zoster virus...
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PMID: 18852442
PDF is available here.
PDF is available here.
Journal of Virology (82)20 2008
Abstract
We examined the effect of dendritic cells (DCs) on the level of HSV-1 latency in trigeminal ganglia (TGs) of ocularly infected BALB/c and C57BL/6 mice. We found that immunization of wild-type mice with FMS-like tyrosine kinase 3 ligand (Flt3L) DNA, which increases the number of DCs, increased the am...
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PMID: 18667491
PDF is available here.
PDF is available here.
Abstract
Abstract
The results demonstrate widespread delay in latency in HIV-positive patients, especially in those with prolonged low (below 100 cells/mm(3)) CD4 nadir counts. These findings suggest early diffuse dysfunction of the inner retina results from severe HIV disease even in the HAART era....
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PMID: 18280451
PDF is available here.
PDF is available here.
Abstract
After regional blockade of TNF-alpha in experimental HSV-1 retinitis TNF-alpha seems to possess an antiviral capacity against HSV-1 in the contralateral eye and participates in the immunopathology of HSV-1-induced acute retinitis....
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PMID: 18491128
PDF is available here.
PDF is available here.
Abstract
Rubella virus causes a distinct clinical spectrum of ocular symptoms similar to the FHU syndrome, which suggests that Rubella virus might be involved in the pathogenesis of FHU....
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PMID: 18547534
PDF is available here.
PDF is available here.
Abstract
Data from 72 LT performed in 61 patients (65 eyes) with a mean follow-up of 20.8 months (SD 23.5; range, 3-115) were analyzed. There were 33 males and 28 females with a mean age of 55.8 years (SD: 15.6; range, 20-89). Fifty-eight (80.6%) LT were autografts (40 pterygia, 12 alkali burns, 3 iatrogenic...
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PMID: 18592441
PDF is available here.
PDF is available here.
Abstract
A qualitative multiplex PCR is useful in the screening of viral infections. However, the clinical relevance of the virus infection needs to be evaluated by quantitative real-time PCR....
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PMID: 18408082
PDF is available here.
PDF is available here.
Abstract
Neonatal herpetic infection is uncommon, with an estimated incidence of 1 in 3000 to 20,000 births. Ocular involvement most commonly consists of blepharoconjunctivitis or keratitis. We present a further manifestation of congenital herpes simplex virus (HSV) 2 infection.
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PMID: 18440255
PDF is available here.
PDF is available here.
Abstract
Abstract
The term "condylomata acuminata" typically refers to anogenital warts. From the similarities between the conjunctival lesions described in this patient and typical genital warts, it is our recommendation to refer to these lesions as conjunctival condylomata acuminata. This diagnostic term connotes a...
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PMID: 18520518
PDF is available here.
PDF is available here.
Ophthalmology (115)6 2008
Abstract
Abstract
Abstract
CMV anterior uveitis is not uncommon in our immunocompetent patients and it may present as a recurrent acute or chronic inflammation, resembling PSS, herpetic anterior uveitis, or FHI....
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PMID: 18255045
PDF is available here.
PDF is available here.
Abstract
Six male and two female patients were enrolled in the study. Their ages ranged from 31 to 65 years (mean 43.6+/-13.7). None of them was reported to have any clinical evidence of chronic HCV infection before enrolment and all were negative for HCV serology. CONCLUSION: There was no association betwee...
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PMID: 17618247
PDF is available here.
PDF is available here.
Abstract
Rubeola keratitis in healthy young adults runs a benign course. Recognition of the specific to rubeola keratitis corneal target lesions could aid in the differential diagnosis and prevent the transmission of the disease....
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PMID: 18434843
PDF is available here.
PDF is available here.
Abstract
The role of human papillomavirus (HPV) infection in eye disease is controversial. However, a recent case illustrates the possible role of HPV in conjunctival squamous carcinoma and the potentially devastating effects of this disease. The development of two vaccines to prevent infection with HPV type...
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PMID: 18369059
PDF is available here.
PDF is available here.
Abstract
HSV is not associated with pterygium formation in Taiwan; the pathogenesis of pterygia is still incompletely understood....
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PMID: 18362659
PDF is available here.
PDF is available here.
Abstract
Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti (64)2 2008
Abstract
Altogether 82 samples were taken and 230 DNA analyses were performed. The DNA diagnostics proved the presence of HSV 1 DNA in 28 patients, in one case, VZV DNA was detected, and 16 patients were positive on adenoviruses. The HSV 1 positive samples were confirmed by means of in-house RealTime PCR met...
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PMID: 18419101
PDF is available here.
PDF is available here.
Abstract
Herpes Simplex Virus Type 1 (HSV-1) is a nuclear replicating enveloped virus, usually acquired through direct contact with infected lesions or body fluids (typically saliva). The prevalence of HSV-1 infection increases progressively from childhood, the seroprevalence being inversely related to socio...
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PMID: 18197856
PDF is available here.
PDF is available here.
Ophthalmology (115)2 2008
Abstract
Besides HSV and VZV, CMV must be considered as an etiologic agent in patients with corneal endotheliitis. Cytomegalovirus corneal endotheliitis may be a newly identified clinical entity of reactivated CMV in the anterior chamber of individuals free of accompanying systemic symptoms....
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PMID: 17669498
PDF is available here.
PDF is available here.
Ophthalmology (115)2 2008
Abstract
There were 9 patients with ocular lesions; 1 had nodular episcleritis, 5 presented with acute iridocyclitis, and 3 had retinitis. Four to 12 weeks before the development of ocular manifestations, all of these patients had fever. Although there were no specific changes of iridocyclitis that were diag...
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PMID: 17631967
PDF is available here.
PDF is available here.
Ophthalmology (115)2 2008
Abstract
Despite the posterior location of inflammation, aqueous analyses with PCR and GWC for HSV, VZV, CMV, and T. gondii revealed an infectious cause in 29% of patients with PU....
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PMID: 17669497
PDF is available here.
PDF is available here.
Survey of Ophthalmology (53)4 2008
Abstract
Given the fact that infectious agents contribute to around 18% of human cancers worldwide, it would seem prudent to explore their role in neoplasms of the ocular adnexa: primary malignancies of the conjunctiva, lacrimal glands, eyelids, and orbit. By elucidating the mechanisms by which infectious ag...
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PMID: 18572051
PDF is available here.
PDF is available here.
Abstract
Ophthalmologica (222)5 2008
Abstract
Ten eyes of 6 patients were studied. The mean age was 19.8 years. The mean presenting best corrected visual acuity was 6/45 (range of 6/7.5 to counting fingers). Fundus examination revealed a yellow-orange lesion at the fovea which corresponded to outer neurosensory retina disruption on OCT. Multifo...
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PMID: 18617754
PDF is available here.
PDF is available here.
Abstract
Cytomegalovirus may not be playing a significant role in causation of congenital cataract. The role of serology in identifying causative viral infection for congenital cataract needs to be re-evaluated....
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PMID: 18296799
PDF is available here.
PDF is available here.