Abstract
We describe our experiences, investigations and collaboration studies of avian influenza (H5N1) in Vietnam in association of our cooperative study of pandemic (H1N1) 2009 in Mexico. Effective treatment methods for critical illness due to influenza will be discussed from medical, regional and global...
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PMID: 20845757
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Abstract
These results suggested that rHuGM-CSF might be an effective and potential protection for H1N1 influenza virus-induced pneumonia.
Copyright 2010 Elsevier Ltd. All rights reserved....
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PMID: 20427198
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Abstract
We assumed that a rare HCMV and M. pneumoniae coinfection was the aetiology of the fulminant pneumonia. Under broad antibiotic and antiviral treatment, the situation of the patient improved only very slowly....
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PMID: 20466842
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Douglas H Esposito,
Tracie J Gardner,
Eileen Schneider,
Lauren J Stockman,
Jacqueline E Tate,
Catherine A Panozzo,
Cheryl L Robbins,
Sue A Jenkerson,
Lorita Thomas,
Colleen M Watson,
Aaron T Curns,
Dean D Erdman,
Xiaoyan Lu,
Theresa Cromeans,
Mary Westcott,
Catherine Humphries,
Jayme Ballantyne,
Gayle E Fischer,
Joseph B McLaughlin,
Gregory Armstrong and
Larry J Anderson
Abstract
During a community outbreak in Alaska, HAdV-14 appeared to have spread mostly among close contacts and not widely in the community. Demographic characteristics and illness patterns among the case patients were similar to those observed in other recent outbreaks of HAdV-14 infection in the United Sta...
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PMID: 20533881
PDF is available here.
Abstract
We retrospectively assessed HRCT images of 5 patients (all male patients, age range 39-70 years; mean 62 years) with HSV pneumonia. The specific pathological findings that allowed for a definite diagnosis of HSV pneumonia included the presence of intranuclear inclusion bodies on haematoxylin and eos...
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PMID: 20442279
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J S Nguyen-Van-Tam,
P J M Openshaw,
A Hashim,
E M Gadd,
W S Lim,
M G Semple,
R C Read,
B L Taylor,
S J Brett,
J McMenamin,
J E Enstone,
C Armstrong,
K G Nicholson and
Influenza Clinical Information Network (FLU-CIN)
Abstract
Pandemic H1N1 infection causes disease requiring hospitalisation of previously fit individuals as well as those with underlying conditions. An abnormal chest x-ray or a raised CRP level, especially in patients who are recorded as obese or who have pulmonary conditions other than asthma or COPD, indi...
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PMID: 20627925
PDF is available here.
Abstract
In June 2000, 21 adult harbor seals Phoca vitulina richardsii were found dead along a localized section of the central California coast. Necropsy of 5 fresh carcasses revealed pulmonary congestion, consolidation, and hemorrhage. Histopathological changes in lungs from 2 of these seals included a nec...
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PMID: 20662367
PDF is available here.
Abstract
We first demonstrated that human catalase could attenuate acute oxidative injury in lung tissues following influenza-induced pneumonia. Mice were infected with influenza virus H1N1 (FM1 strain) and treated with recombinant human catalase (50,000 U/kg) by inhalation. The survival time and survival ra...
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PMID: 19957025
PDF is available here.
Abstract
A new pandemic influenza A (H1N1) virus has emerged and rapidly spread throughout the world. The clinical and pathological findings associated with severe illness in Pandemic (H1N1) 2009 and the risk factors are similar to the high pathogenic avian influenza (H5N1). The effective treatment methods f...
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PMID: 20848860
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Abstract
In mid-May 2007, a respiratory disease outbreak associated with adenovirus, serotype B14 (Ad14), was recognized at a large military basic training facility in Texas. The affected population was highly mobile; after the 6-week basic training course, trainees immediately dispersed to advanced training...
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PMID: 20409365
PDF is available here.
Abstract
A novel swine-origin H1N1 influenza A virus has been identified as the cause of the 2009 influenza pandemic in humans. Since then, infections with the pandemic (H1N1) 2009 influenza virus have been documented in a number of animal species. The first known cases of lethal respiratory disease associat...
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PMID: 20382823
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Abstract
An H3N8 influenza virus closely related to equine influenza virus was identified in racing greyhound dogs with respiratory disease in 2004 and subsequently identified in shelter and pet dogs. Pathologic findings in dogs spontaneously infected with canine influenza virus were compared with lesions in...
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PMID: 20351357
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Abstract
In experiment 1, BRSV challenge resulted in severe respiratory tract disease with low arterial partial pressures of oxygen and lung lesions in most calves from all groups. Maximum change in rectal temperature was significantly greater in seropositive IN vaccinated calves, compared with seronegative...
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PMID: 20433400
PDF is available here.
Abstract
We have used BMT in mice and murine gammaherpesvirus, gammaHV-68, to study the efficacy of adaptive immune responses post-BMT. Five weeks posttransplant, mice have fully reconstituted their hematopoietic lineages in both the lung and periphery. When challenged with virus, however, BMT mice have a re...
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PMID: 20348421
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Abstract
Clinical displays of influenza and influenzal pneumonia, and also main principles antiviral and antibacterial therapy with use Ingavirin are described.
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PMID: 20564947
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Abstract
We describe the clinical course of pneumonia in patients hospitalized with 2009 H1N1 in Korea from August to mid-October 2009. Of 351 patients with a confirmed 2009 H1N1 infection, a total of 17 patients with pneumonia were admitted to an acute care unit. More than half of the patients were between...
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PMID: 20222847
PDF is available here.
Abstract
We hope to offer some insight into potential pitfalls and problems that may be experienced by other centers and provide some potential approaches to addressing these issues....
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PMID: 20101177
PDF is available here.
Abstract
Influenza is a seasonal viral infection associated with significant morbidity and mortality. In 2009, a novel H1N1 influenza A virus emerged and has been classified as a pandemic. In contrast to seasonal influenza, severe disease from pandemic H1N1 seems concentrated in older children and young adul...
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PMID: 19935413
PDF is available here.
Jia-jun Sun,
Chen Li,
Da-wei Wu,
Chen-hua Li,
Wei-hua Qin,
Ya-lin Li,
Qing-yue Liu,
Jin-xiu Li,
Yu-gang Zou,
Dong-qinga Huang,
Jian-jun Xie and
En-jie Li
Abstract
To investigate the clinical feature, treatment and outcome of respiratory failure in patients with 2009 influenza A H1N1 infection in critically ill adults.
A prospective observational study of 18 patients with respiratory failure suffering from 2009 influenza A H1N1 infection admitted between Novem...
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PMID: 20367906
PDF is available here.
Abstract
To study the effect of extracorporeal membrane oxygenation (ECMO) in patients suffering from severe pneumonia complicating influenza A H1N1 by putting lungs in rest to protect the latter.
Five patients with severe pneumonia following influenza A H1N1 were treated with ECMO and different modes of mec...
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PMID: 20367904
PDF is available here.
Abstract
We report the case of a female patient who was admitted after an elective surgery of rectal tumor with suspected bronchoaspiration during anesthetic induction. The patient presented persistent fever despite broad spectrum antibiotic treatment. All cultures were negative for bacterial growth. The che...
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PMID: 20156709
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Abstract
We studied 46 patients with VZV pneumonia, 21 men and 25 women, with a mean age 36 +/-11 y. A contact with an index case was observed in 57%, 76 were active smokers, 6.5% consumed drugs and 2 women were pregnant. The symptoms were: fever (83%), cough (83%), dyspnoea (63%), pleuritic pain (70%), and...
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PMID: 20055724
PDF is available here.
Abstract
We describe the case of a young patient who showed dyspnoea, fever and rapid radiological progression and was simultaneously diagnosed with AEP and 2009 influenza A (H1N1) infection, which was diagnosed by using bronchoalveolar lavage (BAL). We suggest that 2009 influenza A (H1N1) virus should be co...
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PMID: 20335299
PDF is available here.
W Abdullah Brooks,
Doli Goswami,
Mustafizur Rahman,
Kamrun Nahar,
Alicia M Fry,
Amanda Balish,
Nadia Iftekharuddin,
Tasnim Azim,
Xiyan Xu,
Alexander Klimov,
Joseph Bresee,
Carolyn Bridges and
Stephen Luby
Abstract
Influenza is a major contributor to childhood pneumonia both through high influenza infection incidence and high pneumonia prevalence among infected children. Its contribution to early childhood pneumonia appears under-appreciated in high pneumonia-endemic tropical settings. Influenza vaccine trials...
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PMID: 20190613
PDF is available here.
Abstract
We have reviewed the current literature on the impact of viruses in lower respiratory tract infections to elucidate the role of viruses in the pathogenesis of lower respiratory tract infections. The preceding parts of this series provided an introduction to the frequently found viruses, pathogenesis...
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PMID: 20143283
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Alejandro Gómez-Gómez,
Martin Magaña-Aquino,
Christian Garcia-Sepúlveda,
Uciel R Ochoa-Pérez,
Reynaldo Falcón-Escobedo,
Andreu Comas-García,
Saray Aranda-Romo,
Hugo I Contreras-Treviño,
Paulina V Jimenéz-Rico,
Mario A Banda-Barbosa,
Félix Dominguez-Paulin,
J Mario Bernal-Blanco,
Luis F Peréz-González and
Daniel E Noyola
Abstract
We describe the clinical characteristics and outcomes of adults hospitalized with pneumonia during the pandemic (H1N1) 2009 outbreak. Patients admitted to a general hospital in San Luis Potosí, Mexico, from April 10 through May 11, 2009, suspected to have influenza virus-associated pneumonia were e...
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PMID: 20031039
PDF is available here.
Abstract
We retrospectively reviewed the background, clinical features, blood tests, and complications in the 720 children seen for acute respiratory tract infection from July 2004 to December 2005. Of these, 75 (10.5%) were diagnosed with pneumonia due to respiratory syncytial virus (RSV) and 19 (2.6%) with...
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PMID: 20170013
PDF is available here.
Abstract
Heterodirectional changes were found in the parameters of the blood prooxidant and antioxidant systems in bacterial and viral pneumonias. There was a regular and significant increase in MDA levels, spontaneous HCT test, and erythrocyte catalase. At the same tine, CP activity depending on the etiolog...
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PMID: 20564921
PDF is available here.
Abstract
Among 109 individuals with swine flu influenza, 67% have not complicated clinical manifestation and they recovered during 3-4 days. Eight patients developed ARDS and one of them died. Test PCR for influenza A/H1N1 was the basis in diagnostics procedures of the new pandemic influenza confirmation. Os...
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PMID: 20499654
PDF is available here.
Abstract
We observed bacterial superinfections associated with swine flu, ARDS and shock syndrome, secondary bacterial pneumonia and neurological complications. Severe hypoxemia, multilobar pneumonia, and dramatic signs and symptoms progression, were reported in 8 individuals. All patients required admission...
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PMID: 20499655
PDF is available here.
Abstract
Varicella (chickenpox) is a common contagious infection of childhood, with fewer than 2% of the cases occurring in adults. Since the early 1980s the incidence of chickenpox in adults has been increasing and only 7% of them are seronegative for Varicella zoster antibodies. Pneumonia, although rare, i...
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PMID: 20635064
PDF is available here.
Abstract
Being infected with RSV was associated with a more severe clinical presentation of pneumonia, longer illness duration, and increased risk of treatment failure. The severity of RSV infection was age related, infants being more severely affected....
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PMID: 19935451
PDF is available here.
Abstract
The study of the antiviral activity of Russian anti-influenza agents in the cultured MDCK cells demonstrated that arbidol and ribavirin inhibited the reproduction of various influenza A virus strains, including rimantadine- and ozeltamivir-resistant variants, as well as influenza B viruses (IC50 2-8...
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PMID: 20608077
PDF is available here.
Abstract
1. Coronavirus (CoV)-HKU1 accounts for 2.4% of community-acquired pneumonia. 2. Clinical features alone cannot differentiate this entity from other community-acquired pneumonia. 3. Further studies are needed to understand the significance of CoV-HKU1 in upper respiratory tract infection and its pote...
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PMID: 20393227
PDF is available here.
Abstract
We present a case of ARDS secondary to infection with the influenza A (H1N1) virus. The influenza A (H1N1) virus caused a global pandemia 91 years ago, with sporadic outbreaks afterward. The new influenza A pandemia was transmitted from swine to humans. Infection by the influenza A (H1N1) virus can...
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PMID: 19854543
PDF is available here.
Abstract
Adenovirus, a frequent cause of mild respiratory disease in military trainees, can result in severe manifestations when outbreaks are caused by novel viral strains for which there is little pre-existing immunity. Twenty-five basic military trainees (BMTs) were hospitalized with adenovirus pneumonia...
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PMID: 20055071
PDF is available here.
Abstract
The blood prooxidant and antioxidant systems were studied in 165 patients with pneumonia of bacterial and viral etiologies over time. There was a regular and significant increase in the levels of malondialdehyde, spontaneous nitroblue tetrasolium test, and catalase in the red blood cells; in paralle...
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PMID: 20030264
PDF is available here.
Abstract
The use of a comprehensive diagnostic panel for respiratory viral infections may be useful to clarify the epidemiology and clinical impact of viral pathogens in hospitalized adult patients. The occurrence of multiple infections is a common finding and results should be interpreted taking into accoun...
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PMID: 19910888
PDF is available here.
Abstract
Community-acquired pneumonia is a common disease worldwide, with considerable morbidity and mortality. In the United States, pneumonia complicates 0.5 to 1.5 per 1,000 pregnancies. Physiologic adaptations in the respiratory and immunologic systems may increase susceptibility to pulmonary infections...
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PMID: 19888052
PDF is available here.
Abstract
We also address the types of pneumonia caused by hantaviruses, metapneumoviruses and rhinoviruses....
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PMID: 19820817
PDF is available here.
Abstract
The lower respiratory tract of patients affected by COPD is constantly colonized by pathogenic microrganisms such as H. influenzae, M. catarrhalis and S. pneumoniae. Role of bacterial colonization of big and small airways in patients affected by COPD is still unclear but it is likely to play a role...
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PMID: 19696555
PDF is available here.
Abstract
Compared with model group, medium and high dosages of Tankejing Dry Powder inhaler could modulate the expression of NF-kappaB, reduce the level of TNF-alpha, IL-beta, IL-6 in lung tissue (P < 0.05), and reduce the lung index and the death number of animals within 14 days (P < 0.05). CONCLUSION: Tank...
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PMID: 19873739
PDF is available here.
Abstract
We present an immunocompetent woman with viral pneumonia who developed painful linear fissures on the back of the tongue suggestive of herpetic geometric glossitis. The diagnosis was confirmed by both biopsy specimen and immunohistochemistry. As in other cases, the patient promptly responded to trea...
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PMID: 19539852
PDF is available here.
Abstract
In the period of 45-72 day after renal transplantation, 36 cases were found to have significantly lower number of CD4(+)T cells than that before operation. Of the 133 recipients, 12(9.0%, 12/133) had severe pneumonia, during 58-118 days after operation, including 7 with acute respiratory distress sy...
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PMID: 19726354
PDF is available here.
Abstract
Following importations of cases from Mexico and the United States, by 11 May, United Kingdom surveillance activities had detected a total of 65 individuals with confirmed infections caused by the new influenza A(H1N1) virus. The infections were mainly in young people and younger adults and they spre...
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PMID: 19442403
PDF is available here.
Abstract
The purpose of this study was to determine the association between common clinical features in general practice, and chest radiographic findings among children with suspected bacterial or viral pneumonia. The study was prospective hospital-based carried out in Northern Thailand, from 2000 to 2001. O...
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PMID: 19842444
PDF is available here.