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Mupapillomavirus (0)
Articles on Mupapillomavirus
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Identification of an arginine-rich motif in human papillomavirus type 1 E1;E4 protein necessary for E4-mediated inhibition of cellular DNA s...
J Virol 82(18):9056-64 (2008) PMID 18632869 PMCID 2546886
We report here that the HPV1 E4 protein, in the presence of a soluble form of the replication-licensing factor (RLF) Cdc6, inhibits initiation of cellular DNA replication in a mammalian cell-free DNA replication system. Chromatin-binding studies show that E4 blocks replication initiation in vitro by... -
Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.
Science 320(5873):230-3 (2008) PMID 18403710
Cytidine deaminases of the APOBEC3 family all have specificity for single-stranded DNA, which may become exposed during replication or transcription of double-stranded DNA. Three human APOBEC3A (hA3A), hA3B, and hA3H genes are expressed in keratinocytes and skin, leading us to determine whether gene...