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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Viruses (17):
Recent article
Viruses
Abstract
Swimming in ocean water, including ocean water at beaches not impacted by known point sources of pollution, is an increasing health concern. This study was an initial evaluation of the presence of indicator microbes and pathogens and the association among the indicator microbes, pathogens, and envir...
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PMID: 19966020
PDF is available here.
PDF is available here.
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Biochemical Society transactions (38)Pt 1 2010
Abstract
We summarize the current knowledge of the activity of resveratrol against viral infection and describe the possible molecular pathways through which resveratrol exerts its antiviral activity....
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PMID: 20074034
PDF is available here.
PDF is available here.
Biochemical Society transactions (38)Pt 1 2010
Abstract
Proteases play a key role in various pathological processes and several protease inhibitors are already available for treatment. DUBs (deubiquitinating enzymes) constitute one of the largest classes of human proteases and are key effectors of the ubiquitin-proteasome system. This pathway regulating...
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PMID: 20074048
PDF is available here.
PDF is available here.
Abstract
We present a comprehensive survey of reprogramming approaches focusing on gene-delivery systems used for generation of iPS cells from somatic cells, categorize gene-delivery vectors, and discuss their advantages and limitations for somatic cell reprogramming. We include pertinent literature publishe...
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PMID: 20088717
PDF is available here.
PDF is available here.
Abstract
In recent years, the development of powerful viral gene transfer techniques has greatly facilitated the study of gene function. This review summarises some of the viral delivery systems routinely used to mediate gene transfer into cell lines, primary cell cultures and in whole animal models. The sys...
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PMID: 19830583
PDF is available here.
PDF is available here.
Abstract
We have found to be particularly useful in our gene therapy research. An overriding guiding concept that has emerged in the development of synthetic nanodelivery systems is the idea to develop formulations and structures that mimic viruses, whilst retaining the safety elements of synthetic, non-vira...
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PMID: 20127400
PDF is available here.
PDF is available here.
Abstract
Water Research (44)4 2010
Abstract
An empirical formula was developed for determining the vulnerability of unconfined sandy aquifers to virus contamination, expressed as a dimensionless setback distance r(s)(*). The formula can be used to calculate the setback distance required for the protection of drinking water production wells ag...
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PMID: 20110099
PDF is available here.
PDF is available here.
Abstract
We identified the WD repeat protein WDR5 as a VISA-associated protein. WDR5 was recruited to VISA in a viral infection dependent manner. Viral infection also caused translocation of WDR5 from the nucleus to mitochondria. Knockdown of WDR5 impaired the formation of virus-induced VISA-associated compl...
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PMID: 20080758
PDF is available here.
PDF is available here.
Acta Virologica (54)2 2010
Abstract
Over 100 years viruses have fascinated scientists around the world. Although biologists, chemists, physicians, veterinarians, and even physicists attempted to elucidate the nature of viruses, the question still remains "Are viruses alive?" Different theories have aimed at unifying our views of virol...
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PMID: 20545437
PDF is available here.
PDF is available here.
Abstract
We have recently characterized that influenza A virus blocks autophagosome degradation via its matrix protein 2. Matrix protein 2 seems to achieve this macroautophagy inhibition not by its well-characterized proton channel function, but possibly due to its binding to Atg6/Beclin 1, thereby enhancing...
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PMID: 20009549
PDF is available here.
PDF is available here.
Abstract
Respiratory viruses are a constant concern for all demographics. Examples include established viruses such as respiratory syncytial virus (RSV), the leading cause of respiratory infection in infants and young children, and emerging viruses such as severe acute respiratory syndrome (SARS), which reac...
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PMID: 20201109
PDF is available here.
PDF is available here.
Abstract
We found that by using "universal" primers and a single-step PCR diagnostic test, it was difficult to distinguish between non-infective forms of the virus and active IHHNV. Detection of IHHNV was more accurate when we used two alternative molecular strategies, namely 1) single-step PCR amplification...
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PMID: 20957606
PDF is available here.
PDF is available here.
Abstract
We gain greater insight into the interrelationship of viruses and the immune system. Viral-vector vaccines remain the best means to induce cellular immunity and are now showing promise for the induction of strong humoral responses. The potential benefits for global health that are offered by this fi...
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PMID: 19966816
PDF is available here.
PDF is available here.
Human Antibodies (19)1 2010
Abstract
IVIG can be prepared from fractionation of normal human plasma and it is used as a therapeutic drug for treatment of various diseases. IVIG has been for some time the high-growth product within the plasma derived products, at both a global and a national country level. Fractionation was performed ac...
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PMID: 20555125
PDF is available here.
PDF is available here.
Abstract
We initially introduce all possible types of DRV liposomes (in respect to the encapsulated molecule characteristics and/or their applications in therapeutics) and discuss in detail the preparation methodologies for each type....
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PMID: 20072872
PDF is available here.
PDF is available here.
Abstract
Our results show that when targeting two complementary antiviral mechanisms, strongly additive effects could be observed....
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PMID: 20054100
PDF is available here.
PDF is available here.
Abstract
There is growing awareness of the health implications of fact that infectious agents often do not act independently; rather their disease potential is mediated in diverse and significant ways by their relationships with other pathogens. Pathogen-pathogen interaction (PPI), for exampl...
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PMID: 21178409
PDF is available here.
PDF is available here.
Virology Journal (7)1 2010
Abstract
I interferons (IFN-alpha/beta) in biological samples. The amount of IFN is either determined via its ability to suppress a sensitive indicator virus, by an IFN-responding reporter cell line, or by ELISA. These assays however are either time-consuming and lack convenient readouts, or they are rather...
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PMID: 20187932
PDF is available here.
PDF is available here.
Abstract
Abstract
Sewage sludge and treated wastewater when contaminated with enteric virus and discharged into the environment, could pose a human health risk. The aim of study was to verify the presence and viability of enteric viruses in sewage sludge and treated wastewater at a local sewage plant in Florianopolis...
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PMID: 20107281
PDF is available here.
PDF is available here.
Abstract
The 2009 Viral Clearance Symposium (Indianapolis, IN, USA) was held to interactively discuss methods for virus removal and inactivation during biopharmaceutical manufacture. Its origin was the result of worldwide regulatory and industry recognition that challenges, gaps, and opportun...
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PMID: 21516942
PDF is available here.
PDF is available here.
BMC Plant Biology (10) 2010
Abstract
We found that plant miRNAs target plant viruses more efficiently than any other sequences, but also, miRNAs can either preferentially target plant-infecting viruses or target any virus without preference.
Our results show a strong potential for antiviral activity of plant miRNAs and suggest that the...
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PMID: 20594353
PDF is available here.
PDF is available here.
Abstract
TLRs (Toll-like receptors), NLRs (Nod-like proteins) and RLRs (RIG-like receptors), pathogens sensors of innate immunity conference organized by EuroSciCon hosted a large group of scientists from across Europe. The Chairs hoped the meeting would "provide an overview of these three families of recept...
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PMID: 20021301
PDF is available here.
PDF is available here.
Abstract
We investigated more than 460 primate cell lines for Epstein-Barr (EBV), hepatitis B (HBV), hepatitis C (HCV), human immunodeficiency virus type 1 (HIV-1), human T-cell leukemia/lymphoma virus I and II (HTLV-I/-II), and squirrel monkey retrovirus (SMRV) infections for risk assessment. None of the ce...
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PMID: 20454443
PDF is available here.
PDF is available here.