Advanced search×

N-terminal pro-brain natriuretic peptide after myocardial infarction: a marker of cardio-renal function.

Andreas A Luchner, Christian C Hengstenberg, Hannelore H Löwel, Jürgen J Trawinski, Matthias M Baumann, Günter A J GA Riegger, Heribert H Schunkert, and Stephan S Holmer

Hypertension 39(1):99-104 (2002) PMID 11799086

N-terminal pro-brain natriuretic peptide (NT-proBNP) is increased early after acute myocardial infarction. We assessed the relationship of NT-proBNP with left ventricular function and mass as well as with renal function, hemodynamic, and anthropometric variables in 625 outpatients in the chronic phase after myocardial infarction and 465 siblings without infarction (control). NT-proBNP was measured by nonextracted, enzyme-linked, sandwich immunoassay. NT-proBNP was correlated with left ventricular ejection fraction, mass index, and renal function, in addition to infarction history, gender, and age, in univariate and multivariate analysis (all P<35% and concomitant renal dysfunction at a cutoff of 162 pmol/L. NT-proBNP is a biochemical marker of integrated cardio-renal function in the chronic phase after myocardial infarction and a potential diagnostic tool for the detection and exclusion of significant left ventricular dysfunction. Cutoff concentrations have to be chosen according to renal function to optimize the predictive value of NT-proBNP.

Version: za2963e q8za4 q8zb6 q8zc9 q8zd0 q8zed q8zfb q8zgb

Similar articles you may find interesting…

  1. Psychiatric disorders in temporal lobe epilepsy patients over the first year after surgical treatment
    Luis Pintor, Eva Bailles, ... Xavier Setoain

    Seizure 16(3):8 (2007) PMID 17204436

    Surgery in TLE patients does not worsen the global psychopathological status. Presurgical psychiatric morbidity was found to be related to the presence of psychiatric disorders after surgery. Specific psychiatric assessment should be made before and after surgery....
  2. [Septo-optic dysplasia--omitted interdisciplinary clinic entity: report on three patients].
    K K Podobová, H H Urbánková, ... M M Pura

    Cesk Slov Oftalmol 65(2):59-63 (2009) PMID 19408861

    On example of three patients with septo-optic dysplasia the authors present a rare clinical entity involving combined disturbances of endocrine and neurologic systems and variable expressed clinical triad: 1) pituitary aplasia/dysplasia with pituitary hormones deficiency, 2) developmental disturbanc...
  3. [The change of the anti-VEGF agent in the treatment of exceptionally active choroidal neovascular membrane in age-related macular degenerati...
    M M Hovorka

    Cesk Slov Oftalmol 66(3):142-5 (2010) PMID 21137478

    Dosing of anti-VEGF substances results from clinical trials is suitable for treatment majority of patients with choroidal neovascular membrane. Change of anti-VEGF substance is necessary for stabilisation of state on retina in some cases....