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IgA and secretory component (SC) in the third eyelid of domestic animals: a comparative study.

T Schlegel, H Brehm, and W M Amselgruber

Vet Ophthalmol 6(2):157-61 (2003) PMID 12753619

The third eyelid of domestic animals is important for the production and distribution of tears, in removing ocular debris and in protection of the globe, and has significant immunologic functions. Although it is known that tears contain antibodies of the immunoglobulin A (IgA) isotype which are produced mainly by plasma cells of the lacrimal gland, very little is known about the antibody repertoires in the third eyelid of domestic animals. To assess whether IgA is derived from local synthesis, we analyzed the location of IgA-producing cells and the cellular distribution of secretory component (SC) in the third eyelid of domestic animals in a comparative study.

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