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Flavonoids and isoflavonoids with antiplasmodial activities from the root bark of Erythrina abyssinica.

Abiy A Yenesew, Solomon S Derese, Beatrice B Irungu, Jacob O JO Midiwo, Norman C NC Waters, Pamela P Liyala, Hoseah H Akala, Matthias M Heydenreich, and Martin G MG Peter

Planta Med 69(7):658-61 (2003) PMID 12898424

From the root bark of Erythrina abyssinica a new pterocarpene [3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene] and a new isoflav-3-ene [7,4'-dihydroxy-2',5'-dimethoxyisoflav-3-ene] were isolated. In addition, the known compounds erycristagallin, licoagrochalcone A, octacosyl ferulate and triacontyl 4-hydroxycinnamate were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids and isoflavonoids obtained from the roots of this plant showed antiplasmodial activities.

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