Advanced search×

[Pharmacokinetics and bioequivalence of trimebutine dispersive tablet in healthy subjects].

Yao Xue Xue Bao 39(3):208-11 (2004) PMID 15171657

To develop an HPLC-ESI-MS assay for determination of trimebutine in human plasma and to investigate the pharmacokinetics and bioequivalence of two trimebutine tablets in human.

Version: za2963e q8zaf q8zb5 q8zc1 q8zd5 q8ze5 q8zff q8zg3

Similar articles you may find interesting…

  1. Bioequivalence of an ezetimibe/simvastatin combination tablet and coadministration of ezetimibe and simvastatin as separate tablets in healt...

    Int J Clin Pharmacol Ther 44(2):83-92 (2006) PMID 16502768

    The lowest and highest dosage strengths of EZE/SIMVA tablet were bioequivalent to the individual drug components administered together. Given the exact weight multiples of the EZE/SIMVA tablet and linear pharmacokinetics of simvastatin across the marketed dose range, bioequivalence of the intermedia...
  2. A SAS/IML program for simulating pharmacokinetic data.

    Comput Methods Programs Biomed 78(1):39-60 (2005) PMID 15780889

    We designed a novel SAS/IML program to generate pharmacokinetic datasets that reflect the various kinetic, population, and study design characteristics that complicate the bioequivalence evaluation of animal health products. Developing this simulation program within SAS provides an opportunity to ut...
  3. Quantitative determination of amantadine in human plasma by liquid chromatography-mass spectrometry and the application in a bioequivalence ...

    J Pharm Biomed Anal 43(4):7 (2007) PMID 17156962

    A sensitive liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) method is developed and validated for rapid determination of amantadine in human plasma. Desloratadine was used as the internal standard (I.S.). Human plasma (0.2 mL) was first alkalified with 100 microL of sodiu...