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MacroPore resorbable devices in craniofacial surgery.

Ralph E Holmes, Steven R Cohen, G Bryan Cornwall, Kevin A Thomas, Kenneth K Kleinhenz, and Miles Z Beckett

Clin Plast Surg 31(3):393-406, v (2004) PMID 15219746

Resorbable polymer implants have become a compelling option in the treatment of acquired and congenital craniofacial deformities. The resorbable polylactide (PLa) and polyglycolide (PGa) polymers in particular have demonstrated excellent safety profile sin multiple in vitro, animal, and clinical studies and are currently being used in a wide variety of craniofacial applications. In this article, the authors discuss the biomaterial properties of PLa and PGa resorbable implants and provide an overview of the use of these polymers in craniofacial surgery. They conclude by relating their experience with an ongoing clinical series using MacroPore PLDLa and FRP implants for various applications,including Le Fort osteotomies, midface/monobloc internal distraction, and craniosynostosis reconstruction.

DOI: 10.1016/j.cps.2004.03.003
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