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Molecular cloning and sequencing of cDNA encoding urinary stone protein, which is identical to osteopontin.
K K Kohri, Y Y Suzuki, K K Yoshida, K K Yamamoto, N N Amasaki, T T Yamate, T T Umekawa, M M Iguchi, H H Sinohara and T T Kurita
Biochem Biophys Res Commun 184(2):859-64 (1992)
PMID 1575754
We have sequenced a cDNA of urinary stone protein. cDNA sequences show complete homology between urinary stone protein and human osteopontin (bone sialoprotein) (nucleotides 265-886 and 1183-1424). Osteopontin is a recently discovered bone matrix protein which has been implicated in mediating mineral formation within bone extracellular matrix. This result shows that osteopontin is presumably involved in stone formation as stone matrix.
DOI:
Version: za2963e q8zab q8zba q8zcb q8zd9 q8zea q8zf2 q8zg1
DOI:
Version: za2963e q8zab q8zba q8zcb q8zd9 q8zea q8zf2 q8zg1