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Phase I/II trial of adding semisynthetic homoharringtonine in chronic myeloid leukemia patients who have achieved partial or complete cytogenetic response on imatinib.

David D Marin, Jaspal S JS Kaeda, Catharina C Andreasson, Sue M SM Saunders, Marco M Bua, Eduardo E Olavarria, John M JM Goldman, and Jane F JF Apperley

Cancer 103(9):1850-5 (2005) PMID 15786422

A Phase I/II study was designed to show whether the addition of semisynthetic homoharringtonine (sHHT) would reduce the level of residual disease in patients with Ph-positive chronic myeloid leukemia who appeared to have achieved a suboptimal response to imatinib alone.

DOI: 10.1002/cncr.20975
Version: za2963e q8zaa q8zbd q8zc5 q8zd5 q8ze5 q8zfa q8zg5

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