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Isaacs' syndrome (autoimmune neuromyotonia) in a patient with systemic lupus erythematosus.

Journal Watch (General) 32(4):757-8 (2005) PMID 15801039

Patients with systemic lupus erythematosus (SLE) often produce autoantibodies against a large number of antigens. A case of SLE is presented in which muscle twitching and muscle cramps were associated with an autoantibody directed against the voltage-gated potassium channel of peripheral nerves (Isaacs' syndrome).

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