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Parvovirus B19 transmission by a high-purity factor VIII concentrate.

Chuan-ging CG Wu, Bobby B Mason, Julia J Jong, Dean D Erdman, Laurel L McKernan, Meredith M Oakley, Mike M Soucie, Bruce B Evatt, and Mei-ying W MY Yu

Transfusion 45(6):1003-10 (2005) PMID 15935000

Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a solvent/detergent (S/D)-treated, immunoaffinity-purified factor VIII concentrate (antihemophilic factor [human][AHF]) was investigated.

DOI: 10.1111/j.1537-2995.2005.04387.x
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