Randomized placebo-controlled trial of a flavonoid-rich plant extract-based cream in the treatment of rosacea.
J Eur Acad Dermatol Venereol 19(5):564-8 (2005) PMID 16164709
Biological research suggests that vascular changes may play a major role in rosacea pathogenesis. Chrysanthellum indicum is a plant-based extract containing a unique combination of phenylpropenoic acids, flavonoids and saponosids, and has a well-documented effect on vascular wall permeability and increase of the mechanical resistance of capillaries.
DOI: 10.1111/j.1468-3083.2005.01248.x
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