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Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema.

Marcel Bonay, Anne Boutten, Véronique Leçon-Malas, Joëlle Marchal, Paul Soler, Michel Fournier, Guy Leseche, Monique Dehoux, and Bruno Crestani

BMC Pulm Med (2005) PMID 16216128 PMCID 1283976

Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte growth factors or their respective receptors, c-met and keratinocyte growth factor receptor. The aim of our study was to compare the expression of hepatocyte and keratinocyte growth factors and their receptors in lung samples from 3 groups of patients: emphysema; smokers without emphysema and non-smokers without emphysema.

DOI: 10.1186/1471-2466-5-13
Version: za2963e q8za1 q8zb8 q8zc6 q8zd9 q8zef q8zfa q8zgc
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