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Hip arthroplasty for ochronosis.

Servet Kerimoglu, Cetin Onder, Osman Aynaci, and Cagatay H Malkoc

Saudi Med J 26(11):1812-4 (2005) PMID 16311673

Alkaptonuria is a metabolic disorder in which homogentisic acid oxidase is absent. Therefore, homogentisic acid accumulates in cartilage and connective tissues. We can diagnose ochronotic arthropathy, a manifestation of long standing alkaptonuria, through careful radiological, physical, and laboratory examination. In this report, we describe 4 cases of ochronotic arthropathy to which we applied cementless total hip prosthesis due to severe hip involvement.

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