Advanced search×

Bioequivalence of an ezetimibe/simvastatin combination tablet and coadministration of ezetimibe and simvastatin as separate tablets in healthy subjects.

Int J Clin Pharmacol Ther 44(2):83-92 (2006) PMID 16502768

To assess the bioequivalence of an ezetimibe/simvastatin (EZE/SIMVA) combination tablet compared to the coadministration of ezetimibe and simvastatin as separate tablets (EZE + SIMVA).

Version: za2963e q8zae q8zbb q8zc3 q8zd2 q8ze5 q8zf8 q8zg2

Similar articles you may find interesting…

  1. [Pharmacokinetics and bioequivalence of trimebutine dispersive tablet in healthy subjects].

    Yao Xue Xue Bao 39(3):208-11 (2004) PMID 15171657

    Calibration curve was linear over the range of 0.3 - 150 microg x L(-1). The main pharmacokinetic parameters of T1/2, Tmax and Cmax were (9.2 +/- 2.8) h, (1.0 +/- 0.3) h and (40 +/- 20) microg x L(-1) for the reference tablet; (9.2 +/- 2.3) h, (0.9 +/- 0.4) h and (41 +/- 20) microg x L(-1) for the t...
  2. Pharmacokinetics of total and unbound ertapenem in healthy elderly subjects.

    Antimicrob Agents Chemother 48(2):521-4 (2004) PMID 14742204

    Ertapenem is a new once-a-day parenteral carbapenem antimicrobial agent. The pharmacokinetics of unbound and total concentrations of ertapenem in plasma were investigated in elderly subjects and compared with historical data from young adults. In a single- and multiple-dose study, healthy elderly ma...
  3. Synergistic influence of Abcb1 and Abcc2 on disposition and sterol lowering effects of ezetimibe in rats.

    J Pharm Sci 99(1):422-9 (2010) PMID 19504475

    Pharmacokinetics of the sterol-lowering drug ezetimibe (EZ) is influenced by intestinal ABCB1 and ABCC2. This study in Lew.1W rats with "chemical" and genetic Abcb1 and Abcc2 deficiency was initiated to evaluate the individual contribution of both efflux carriers to the overall dispo...